Cloning Entangled Qubits to Scales One Can See

By amplifying photonic qubits it is possible to produce states that contain enough photons to be seen with a human eye, potentially bringing quantum effects to macroscopic scales [1]. In this paper we theoretically study quantum states obtained by amplifying one side of an entangled photon pair with different types of optical cloning machines for photonic qubits. We propose a detection scheme that involves lossy threshold detectors (such as human eye) on the amplified side and conventional photon detectors on the other side. We show that correlations obtained with such coarse-grained measurements prove the entanglement of the initial photon pair and do not prove the entanglement of the amplified state. We emphasize the importance of the detection loophole in Bell violation experiments by giving a simple preparation technique for separable states that violate a Bell inequality without closing this loophole. Finally we analyze the genuine entanglement of the amplified states and its robustness to losses before, during and after amplification.Comment: 15 pages, 9 figure

Quantum experiments with human eyes as detectors based on cloning via stimulated emission

We show theoretically that the multi-photon states obtained by cloning single-photon qubits via stimulated emission can be distinguished with the naked human eye with high efficiency and fidelity. Focusing on the "micro-macro" situation realized in a recent experiment [F. De Martini, F. Sciarrino, and C. Vitelli, Phys. Rev. Lett. 100, 253601 (2008)], where one photon from an original entangled pair is detected directly, whereas the other one is greatly amplified, we show that performing a Bell experiment with human-eye detectors for the amplified photon appears realistic, even when losses are taken into account. The great robustness of these results under photon loss leads to an apparent paradox, which we resolve by noting that the Bell violation proves the existence of entanglement before the amplification process. However, we also prove that there is genuine micro-macro entanglement even for high loss.Comment: 5 pages, 3 figure

Sildenafil dosed concomitantly with bosentan for adult pulmonary arterial hypertension in a randomized controlled trial

BACKGROUND: Few controlled clinical trials exist to support oral combination therapy in pulmonary arterial hypertension (PAH). METHODS: Patients with PAH (idiopathic [IPAH] or associated with connective tissue disease [APAH-CTD]) taking bosentan (62.5 or 125 mg twice daily at a stable dose for ≥3 months) were randomized (1:1) to sildenafil (20 mg, 3 times daily; n = 50) or placebo (n = 53). The primary endpoint was change from baseline in 6-min walk distance (6MWD) at week 12, assessed using analysis of covariance. Patients could continue in a 52-week extension study. An analysis of covariance main-effects model was used, which included categorical terms for treatment, baseline 6MWD (<325 m; ≥325 m), and baseline aetiology; sensitivity analyses were subsequently performed. RESULTS: In sildenafil versus placebo arms, week-12 6MWD increases were similar (least squares mean difference [sildenafil-placebo], -2.4 m [90% CI: -21.8 to 17.1 m]; P = 0.6); mean ± SD changes from baseline were 26.4 ± 45.7 versus 11.8 ± 57.4 m, respectively, in IPAH (65% of population) and -18.3 ± 82.0 versus 17.5 ± 59.1 m in APAH-CTD (35% of population). One-year survival was 96%; patients maintained modest 6MWD improvements. Changes in WHO functional class and Borg dyspnoea score and incidence of clinical worsening did not differ. Headache, diarrhoea, and flushing were more common with sildenafil. CONCLUSIONS: Sildenafil, in addition to stable (≥3 months) bosentan therapy, had no benefit over placebo for 12-week change from baseline in 6MWD. The influence of PAH aetiology warrants future study

Coarse Graining Makes It Hard to See Micro-Macro Entanglement

Observing quantum effects such as superpositions and entanglement in macroscopic systems requires not only a system that is well protected against environmental decoherence, but also sufficient measurement precision. Motivated by recent experiments, we study the effects of coarse-graining in photon number measurements on the observability of micro-macro entanglement that is created by greatly amplifying one photon from an entangled pair. We compare the results obtained for a unitary quantum cloner, which generates micro-macro entanglement, and for a measure-and-prepare cloner, which produces a separable micro-macro state. We show that the distance between the probability distributions of results for the two cloners approaches zero for a fixed moderate amount of coarse-graining. Proving the presence of micro-macro entanglement therefore becomes progressively harder as the system size increases.Comment: 5 pages, 3 figure

Tidally induced brown dwarf and planet formation in circumstellar discs

Most stars are born in clusters and the resulting gravitational interactions between cluster members may significantly affect the evolution of circumstellar discs and therefore the formation of planets and brown dwarfs. Recent findings suggest that tidal perturbations of typical circumstellar discs due to close encounters may inhibit rather than trigger disc fragmentation and so would seem to rule out planet formation by external tidal stimuli. However, the disc models in these calculations were restricted to disc radii of 40 AU and disc masses below 0.1 M_sun. Here we show that even modest encounters can trigger fragmentation around 100 AU in the sorts of massive (~0.5 M_sun), extended (>=100 AU) discs that are observed around young stars. Tidal perturbation alone can do this, no disc-disc collision is required. We also show that very-low-mass binary systems can form through the interaction of objects in the disc. In our computations, otherwise non-fragmenting massive discs, once perturbed, fragment into several objects between about 0.01 and 0.1 M_sun, i.e., over the whole brown dwarf mass range. Typically these orbit on highly eccentric orbits or are even ejected. While probably not suitable for the formation of Jupiter- or Neptune-type planets, our scenario provides a possible formation mechanism for brown dwarfs and very massive planets which, interestingly, leads to a mass distribution consistent with the canonical substellar IMF. As a minor outcome, a possible explanation for the origin of misaligned extrasolar planetary systems is discussed.Comment: 9 pages, 5 figures, uses emulateapj. Published in ApJ. Minor changes to match published version. For associated media files see http://www.astro.uni-bonn.de/~webaiub/english/downloads.ph

Guidelines for Best Practice and Quality Checking of Ortho Imagery

For almost 10 years JRC's ¿Guidelines for Best Practice and Quality Control of Ortho Imagery¿ has served as a reference document for the production of orthoimagery not only for the purposes of CAP but also for many medium-to-large scale photogrammetric applications. The aim is to provide the European Commission and the remote sensing user community with a general framework of the best approaches for quality checking of orthorectified remotely sensed imagery, and the expected best practice, required to achieve good results. Since the last major revision (2003) the document was regularly updated in order to include state-of-the-art technologies. The major revision of the document was initiated last year in order to consolidate the information that was introduced to the document in the last five years. Following the internal discussion and the outcomes of the meeting with an expert panel it was decided to adopt as possible a process-based structure instead of a more sensor-based used before and also to keep the document as much generic as possible by focusing on the core aspects of the photogrammetric process. Additionally to any structural changes in the document new information was introduced mainly concerned with image resolution and radiometry, digital airborne sensors, data fusion, mosaicking and data compression. The Guidelines of best practice is used as the base for our work on the definition of technical specifications for the orthoimagery. The scope is to establish a core set of measures to ensure sufficient image quality for the purposes of CAP and particularly for the Land Parcel Identification System (PLIS), and also to define the set of metadata necessary for data documentation and overall job tracking.JRC.G.3-Agricultur

The ROS wheel: refining ROS transcriptional footprints

In the last decade, microarray studies have delivered extensive inventories of transcriptome-wide changes in messenger RNA levels provoked by various types of oxidative stress in Arabidopsis (Arabidopsis thaliana). Previous cross-study comparisons indicated how different types of reactive oxygen species (ROS) and their subcellular accumulation sites are able to reshape the transcriptome in specific manners. However, these analyses often employed simplistic statistical frameworks that are not compatible with large-scale analyses. Here, we reanalyzed a total of 79 Affymetrix ATH1 microarray studies of redox homeostasis perturbation experiments. To create hierarchy in such a high number of transcriptomic data sets, all transcriptional profiles were clustered on the overlap extent of their differentially expressed transcripts. Subsequently, meta-analysis determined a single magnitude of differential expression across studies and identified common transcriptional footprints per cluster. The resulting transcriptional footprints revealed the regulation of various metabolic pathways and gene families. The RESPIRATORY BURST OXIDASE HOMOLOG F-mediated respiratory burst had a major impact and was a converging point among several studies. Conversely, the timing of the oxidative stress response was a determining factor in shaping different transcriptome footprints. Our study emphasizes the need to interpret transcriptomic data sets in a systematic context, where initial, specific stress triggers can converge to common, aspecific transcriptional changes. We believe that these refined transcriptional footprints provide a valuable resource for assessing the involvement of ROS in biological processes in plants

Wave Function Shredding by Sparse Quantum Barriers

We discuss a model in which a quantum particle passes through $\delta$ potentials arranged in an increasingly sparse way. For infinitely many barriers we derive conditions, expressed in terms ergodic properties of wave function phases, which ensure that the point and absolutely continuous parts are absent leaving a purely singularly continuous spectrum. For a finite number of barriers, the transmission coefficient shows extreme sensitivity to the particle momentum with fluctuation in many different scales. We discuss a potential application of this behavior for erasing the information carried by the wave function.Comment: 4 pages ReVTeX with 3 epsf figure

Belowground ectomycorrhizal communities in three Norway spruce stands with different degrees of decline in the Czech Republic

We investigated the ectomycorrhizal communities on the roots of adult trees and seedlings associated with three Norway spruce stands in the Czech Republic using morphological and molecular tools. The stands had different degrees of forest decline due to air pollution. The aims of the study were to obtain information about the belowground ectomycorrhizal community in a heavily damaged spruce forest and to assess whether missing ectomycorrhizal fungal partners could be one of the reasons for the observed lack of regeneration. The ectomycorrhizal species richness on the roots of adult trees was significantly lower in the heavily damaged site Mumlavska hora than in the other two, but less drastically so than that found in a fruitbody survey. The roots of adult trees and seedlings were fully mycorrhizal at this site although they were less species-rich. The most abundant ectomycorrhizal species on the root system of adult trees in all three forest stands was Tylospora fibrillosa, a member of the athelioid clade. It made up over 60% of root tips in Mumlavska hora and its proportion was at least twice that in the other two sites. This species was also an efficient colonizer of roots from seedlings, in particular, in the most damaged site. The different soil properties in this site may have caused the observed differences in the ectomycorrhizal species richness and composition. For example, cation exchange capacity and soil base saturation were lower and the soil more often saturated. However, the number of living trees and their defoliation status may well directly impact the ectomycorrhizal species composition by presumably affecting the amount of carbon delivered to the symbiotic fungal partners. Athelioids and thelephoroids are an important component of the belowground ectomycorrhizal community in most temperate and boreal forests, but the role they play might even be more crucial in stressed forest ecosystems. Based on our results, we suggest that factors other than missing ectomycorrhizal inoculum constrain natural regeneration in the heavily damaged site Mumlavska hor