Isolation and Characterization of New 24 Microsatellite DNA Markers for Golden Cuttlefish (Sepia esculenta)

Twenty-four microsatellite DNA markers were isolated and characterized for golden cuttlefish (Sepia esculenta) from a (GT)13—enriched genomic library. Loci were tested in 48 individuals from Jiaozhou bay of China. The numbers of alleles per locus ranged from two to 25 with an average of 10.3. The observed and expected heterozygosities ranged from 0.063 to 0.896 and from 0.137 to 0.953, with averages of 0.519 and 0.633, respectively. Six loci significantly deviated from Hardy-Weinberg equilibrium after Bonferroni’s correction and no significant linkage disequilibrium between loci pairs was detected. These microsatellite markers would be useful for analyzing the population genetic structure to make conservation and management decisions for S. esculenta

An Inexact Newton-Type Method for Inverse Singular Value

In this paper, an inexact Newton-type approach is proposed for solving inverse singu- lar value problems. We show that the method converges superlinearly. This method can reduce signi¯cantly the oversolving problem of the Newton-type method and improve the e±ciency. Numerical experiments is also presented to illustrate our results

Glycyrrhizic acid-phospholipid complex: preparation process optimization and therapeutic and pharmacokinetic evaluation in rats

The purpose of the present study was to prepare glycyrrhizic acid-phospholipid complex (GL-PLC) as to improve the oral bioavailability of glycyrrhizic acid (GL), enhance the drug efficacy and reduce the side effects. The uniform experimental design approach was utilized for the process optimization in order to obtain the satisfactory complex. The results of comparison between GL-PLC and free GL indicated that the anti-inflammatory activity of the phospholipid complex was significantly higher than that of free GL at the same dose. The results of pharmacokinetic study displayed that the plasma concentration of glycyrrhetic acid, the metabolite of GL in vivo, increased after oral administration of GL-PLC. The Cmax of GL-PLC was 2.14 times higher than that of free glycyrrhizic acid, while the AUC of GL-PLC was 1.74 times higher than that of free GL. The results proved that GL-PLC improved the lipophilic property of GL, increased the bioavailability and anti-inflammatory activity.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Interdigitated Back‐Contacted Carbon Nanotube–Silicon Solar Cells

Carbon/silicon heterojunctions provide a new perspective for silicon solar cells and in particular those made from carbon nanotubes (CNTs) have already achieved industrial-level power conversion efficiency and device size when using organic passivation and a back-junction design. However, the current state of the art device geometry for silicon photovoltaics is the interdigitated back contact (IBC) cell and this has yet to be demonstrated for CNT/Si solar cells due to the complexity of fabricating the required patterns. Herein, IBC-CNT solar cells are demonstrated via the simple spin coating of a conductive hole-selective passivating film and the evaporation of buried silicon oxide/magnesium electron-selective contacts for both polarities. The CNT coverage area fraction (fCNT) and the gap between the two polarities are optimized to minimize electrical shading loss and ensure high photocarrier collection. Large-area (4.76 cm2) highly efficient (17.53%) IBC-CNT solar cells with a Voc of 651 mV and Jsc of 40.56 mA cm−2 are demonstrated and are prepared with one alignment step for the CNT/Si contact, and photolithographic-free and room-temperature processes. These performance parameters are among the best for solution-processed dopant-free IBC schemes and indicate the feasibility of using low-dimensional carbon materials in IBC solar cells

Simplified Models for LHC New Physics Searches

This document proposes a collection of simplified models relevant to the design of new-physics searches at the LHC and the characterization of their results. Both ATLAS and CMS have already presented some results in terms of simplified models, and we encourage them to continue and expand this effort, which supplements both signature-based results and benchmark model interpretations. A simplified model is defined by an effective Lagrangian describing the interactions of a small number of new particles. Simplified models can equally well be described by a small number of masses and cross-sections. These parameters are directly related to collider physics observables, making simplified models a particularly effective framework for evaluating searches and a useful starting point for characterizing positive signals of new physics. This document serves as an official summary of the results from the "Topologies for Early LHC Searches" workshop, held at SLAC in September of 2010, the purpose of which was to develop a set of representative models that can be used to cover all relevant phase space in experimental searches. Particular emphasis is placed on searches relevant for the first ~50-500 pb-1 of data and those motivated by supersymmetric models. This note largely summarizes material posted at http://lhcnewphysics.org/, which includes simplified model definitions, Monte Carlo material, and supporting contacts within the theory community. We also comment on future developments that may be useful as more data is gathered and analyzed by the experiments.Comment: 40 pages, 2 figures. This document is the official summary of results from "Topologies for Early LHC Searches" workshop (SLAC, September 2010). Supplementary material can be found at http://lhcnewphysics.or

The impact of climate change on infectious disease transmission: perceptions of CDC health professionals in Shanxi Province, China

There have been increasing concerns about the challenge of emerging and re-emerging infectious diseases due to climate change, especially in developing countries including China. Health professionals play a significant role in the battle to control and prevent infectious diseases. This study therefore aims to investigate the perceptions and attitudes of health professionals at the Centers for Disease Control and Prevention (CDC) in different levels in China, and to consider adaptation measures to deal with the challenge of climate change. In 2013, a cross-sectional questionnaire survey was undertaken among 314 staff in CDCs in Shanxi Province, China, whose routine work involves disease control and prevention. Data were analyzed using descriptive methods and logistic regression. A majority of the CDC staff were aware of the health risks from climate change, especially its impacts on infectious disease transmission in their jurisdictions, and believed climate change might bring about both temporal and spatial change in transmission patterns. It was thought that adaptation measures should be established including: strengthening/improving currently existing disease surveillance systems and vector monitoring; building CDC capacity in terms of infrastructure and in-house health professional training; development and refinement of relevant legislation, policies and guidelines; better coordination among various government departments; the involvement of the community in infectious disease interventions; and collaborative research with other institutions. This study provides a snapshot of the understanding of CDC staff regarding climate change risks relevant to infectious diseases and adaptation in China. Results may help inform future efforts to develop adaptation measures to minimize infectious disease risks due to climate change.Junni Wei, Alana Hansen, Ying Zhang, Hong Li, Qiyong Liu, Yehuan Sun, Shulian Xue, Shufang Zhao, Peng B

Precision Higgs physics at the CEPC

The discovery of the Higgs boson with its mass around 125 GeV by the ATLAS and CMS Collaborations marked the beginning of a new era in high energy physics. The Higgs boson will be the subject of extensive studies of the ongoing LHC program. At the same time, lepton collider based Higgs factories have been proposed as a possible next step beyond the LHC, with its main goal to precisely measure the properties of the Higgs boson and probe potential new physics associated with the Higgs boson. The Circular Electron Positron Collider~(CEPC) is one of such proposed Higgs factories. The CEPC is an $e^+e^-$ circular collider proposed by and to be hosted in China. Located in a tunnel of approximately 100~km in circumference, it will operate at a center-of-mass energy of 240~GeV as the Higgs factory. In this paper, we present the first estimates on the precision of the Higgs boson property measurements achievable at the CEPC and discuss implications of these measurements.Comment: 46 pages, 37 figure

An Inexact Newton-Type Method for Inverse Singular Value Problems

In this paper, an inexact Newton-type approach is proposed for solving inverse singular value problems. We show that the method converges superlinearly. This method can reduce significantly the oversolving problem of the Newton-type method and improve the efficiency. Numerical experiments is also presented to illustrate our results. Keywords. Inverse problem, singular value, Newton’s method, root-convergence rate AMS subject classifications. 15A29, 15A18, 65F15, 65F18