27 research outputs found

    Asteroid and comet flux in the neighborhood of the earth

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    Significant advances in the knowledge and understanding of the flux of large solid objects in the neighborhood of Earth have occurred. The best estimates of the collision rates with Earth of asteroids and comets and the corresponding production of impact craters are presented. Approximately 80 Earth-crossing asteroids were discovered through May 1988. Among 42 new Earth-crossing asteroids found in the last decade, two-thirds were discovered from observations at Palomar Observatory and 15 were discovered or independently detected in dedicated surveys with the Palomar Observatory and 15 were discovered or independently detected in dedicated surveys with the Palomar 46 cm Schmidt. Probabilities of collision with Earth have been calculated for about two-thirds of the known Earth-crossing asteroids. When multiplied by the estimated population of Earth-crossers, this yields an estimated present rate of collision about 65 pct higher than that previously reported. Spectrophotometric data obtained chiefly in the last decade show that the large majority of obvserved Earth-crossers are similar to asteroids found in the inner part of the main belt. The number of discovered Earth-crossing comets is more than 4 times greater than the number of known Earth-crossing asteroids, but reliable data on the sizes of comet nuclei are sparse. The flux of comets almost certainly was highly variable over late geologic time, owing to the random perturbation of the Oort comet cloud by stars in the solar neighborhood

    Positive Psychology in Sales: Integrating Psychological Capital

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    As positive psychology moves into the workplace, researchers have been able to demonstrate the desirable impact of positive organizational behavior. Specifically, psychological capital (PsyCap) improves employee attitudes, behaviors, and performance. Advancing PsyCap in sales research is important given the need for a comprehensive positive approach to drive sales performance, offset the high cost of salesperson turnover, improve cross-functional sales interfaces, and enrich customer relationships. The authors provide an integrative review of PsyCap, discuss its application in sales, and advance an agenda for future research. Research prescriptions are organized according to individual-level, intra-organizational, and extra-organizational outcomes pertinent to the sales field

    The majority of the CCHFV-M vaccinated mice developed both IgG1 and IgG2c responses following three vaccinations.

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    <p>Prior to challenge, CCHFV-specific antibody isotypes and the antibody avidity were examined by ELISA against the CCHF<sub>VLP</sub>. A) The CCHFV-specific IgG1 and IgG2c response in individual mice following three vaccinations. Pooled sera from IFNAR<sup>-/-</sup> and WT C57BL/6 mice vaccinated with empty vector were tested concurrently and had no detectable signal. B) The avidity of the CCHFV-specific antibody response in vaccinated mice following three vaccinations was measured. For (A) and (B) mice that died after CCHFV challenge are shown in red. *Two-way ANOVA, confidence intervals were set to 95%.</p

    <i>In vitro</i> expression of the glycoprotein genes from the CCHFV-M DNA vaccine plasmid.

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    <p>A) The total (permeabilized cells) and surface presence (non-permeabilized cells) of G<sub>C</sub> was examined 44 h after transfection of COS-7 cells with wild-type CCHFV-M, optimized CCHFV-M, or empty vector, the maximum expression was seen at 250 ng of each plasmid (shown). B) <i>In vitro</i> expression by Western blot of G<sub>N</sub> (37 kDa) and G<sub>C</sub> (75 kDa) in COS-7 cells 44 h after transfection of CCHFV-M or empty vector, 250 ng of each plasmid.</p
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