Wanita: Wanna Eat? Wanna Eat?

1. Far off in Spain, when you\u27re stuck on a Jane,You must dress up real prettyAnd sing her a ditty like this;Chadadee, Chadada, Chadadee. ChadadaIn Barcelony, I met a bolony who used to make me sing that wayChadadee, Chadada, Chadadee. ChadadaIt was on her that I squandered all my doughTrying to keep her well fedAll that she weighed was a half a ton or soNo wonder I was misled. CHORUSI called her my sweet WanitaWanna eat wanna eat? WanitaAll that I\u27d ever do was feed herAnd this dizzy skirt had steak for dessert,She\u27s some food assassin, WanitaI declare no one there can beat herTen meals a day it took to feed this gal of mine,She\u27s on a diet now, she\u27s only eating nineSo I said Farewell sweet Wanita Wanna eat? Wanna eat? so do I. 2. She\u27d start each meal with a plateful of vealConsomme soon would follow,And she\u27d always swallow like this:Chadadee, Chadada, Chadadee. ChadadaHer demitasse she would take in a glass and she\u27d drink it in most any key;Chadadee, Chadada, Chadadee. Chadada,Once I was happy and prosperous it\u27s trueBut little did I suspectWhat awful things this girl\u27s appetite could doMy little bankroll was wrecked. CHORUSI called her my sweet WanitaWanna eat wanna eat? WanitaWrapped in a table cloth I\u27d greet herAnd I\u27d be a wreck when I got the check,I prayed that she\u27d get indigestionBut such luck it was out of the questionThey say that nanny goats eat tomato cans and suchBut she eats lots of things that nanny goats won\u27t touchSo I said farewell sweet Wanita Wanna eat? Wanna eat? pay the check

The Grid as Organizing Principle of Space, Information, Time, and Display

Over the past several centuries, the grid has colonized nearly every aspect of human life. This text traces the development of the grid in technology and art, and links the grid’s proliferation to the rise of modern governance. The grid has become the primary tool by which government exerts social control via the production of spectacle. As such, artists have increasingly recognized the grid as a central problematic to confront rather than reiterate. Within this context, I consider two of my videos: Today’s News (2020) and Tiles (2020)

Deedle Deedle Dum

https://digitalcommons.library.umaine.edu/mmb-vp/1294/thumbnail.jp

Substrate Scope Analysis of Biocatalytic Halogenation on Complex Substrates

Malbrancheamide is a fungal natural product with significant vasorelaxation effects and potential as a cardiovascular therapeutic. The dichlorination of the indole ring is key for its biological activity, and this transformation is performed by the flavin dependent halogenase MalA. This enzyme utilizes a proposed chloramine lysine intermediate to iteratively and selectively chlorinate its natural substrate premalbrancheamide. Halogenases can provide orthogonal selectivity to many chemical methods, making them useful for pharmaceutical applications, while providing selective methods for late-stage functionalization. This investigation focuses on the substrate scope of the halogenase on complex pharmaceutically relevant substrates in collaboration with the Novartis Institutes for Biomedical Research. The bromination and chlorination reaction conditions were optimized, and the products were structurally characterized by NMR spectroscopy to gain further understanding of the versatility of the wild type enzyme and its mutants

Substrate Scope Analysis of Biocatalytic Halogenation on Complex Substrates

Malbrancheamide is a fungal natural product with significant vasorelaxation effects and potential as a cardiovascular therapeutic. The dichlorination of the indole ring is key for its biological activity, and this transformation is performed by the flavin dependent halogenase MalA. This enzyme utilizes a proposed chloramine lysine intermediate to iteratively and selectively chlorinate its natural substrate premalbrancheamide. Halogenases can provide orthogonal selectivity to many chemical methods, making them useful for pharmaceutical applications, while providing selective methods for late-stage functionalization. This investigation focuses on the substrate scope of the halogenase on complex pharmaceutically relevant substrates in collaboration with the Novartis Institutes for Biomedical Research. The bromination and chlorination reaction conditions were optimized, and the products were structurally characterized by NMR spectroscopy to gain further understanding of the versatility of the wild type enzyme and its mutants

When You\u27re Near

Illustration of man holding a woman\u27s handhttps://scholarsjunction.msstate.edu/cht-sheet-music/5521/thumbnail.jp

Deedle Deedle Dum

Large font title with dancers in backgroundhttps://scholarsjunction.msstate.edu/cht-sheet-music/12646/thumbnail.jp

Energy Harvesting with a Liquid-Metal Microfluidic Influence Machine

We describe and demonstrate a new energy harvesting technology based on a microfluidic realization of a Wimshurst influence machine. The prototype device converts the mechanical energy of a pressure-driven flow into electrical energy, using a multiphase system composed of droplets of liquid mercury surrounded by insulating oil. Electrostatic induction between adjacent metal droplets drives charge through external electrode paths, resulting in continuous charge amplification and collection. We demonstrate a power output of 4 nW from the initial prototype and present calculations suggesting that straightforward device optimization could increase the power output by more than 3 orders of magnitude. At that level the power efficiency of this energy harvesting mechanism, limited by viscous dissipation, could exceed 90%. The microfluidic context enables straightforward scaling and parallelization, as well as hydraulic matching to a variety of ambient mechanical energy sources such as human locomotion.Comment: 7 pages, 7 figure

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts