3,564 research outputs found

    Characteristics of a cohort of high-risk men who have sex with men on pre-exposure prophylaxis reporting transgender sexual partners.

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    Transgender people continue to be at high-risk for HIV acquisition, but little is known about the characteristics of their sexual partners. To address this gap, we examined sociodemographic and sexual characteristics of cisgender men who have sex with men (MSM) on pre-exposure prophylaxis (PrEP) reporting transgender sexual partners.A cohort of 392 MSM in southern California in a randomized clinical trial for PrEP adherence were followed from 2013 to 2016. Multivariable generalized estimating equation and logistic models identified characteristics of MSM reporting transgender sexual partners and PrEP adherence.Only 14 (4%) MSM reported having transgender sexual partners. MSM were more likely to report transgender partners if they were African American, had incident chlamydia, reported injection drug-using sexual partners, or received items for sex. Most associations remained significant in the multivariable model: African American (adjusted odds ratio [AOR] 11.20, P = .01), incident chlamydia (AOR 3.71, P = .04), and receiving items for sex (AOR 5.29, P = .04). There were no significant differences in PrEP adherence between MSM reporting transgender partners and their counterpart.MSM who report transgender sexual partners share characteristics associated with individuals with high HIV prevalence. Identifying this group distinct from larger cohorts of MSM could offer new HIV prevention opportunities for this group of MSM and the transgender community

    Improving Institutional Effectiveness: Description And Application Of An Implementation Model

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    The authors describe a model of implementation effectiveness and a description of how it was applied at the University of New England, building routine practice developmentally by paying attention to implementation climate and values fit variables

    Opening the door to greater phylogeographic inference in Southeast Asia: Comparative genomic study of five codistributed rainforest bird species using target capture and historical DNA

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    Indochina and Sundaland are biologically diverse, interconnected regions of Southeast Asia with complex geographic histories. Few studies have examined phylogeography of bird species that span the two regions because of inadequate population sampling. To determine how geographic barriers/events and disparate dispersal potential have influenced the population structure, gene flow, and demographics of species that occupy the entire area, we studied five largely codistributed rainforest bird species: Arachnothera longirostra, Irena puella, Brachypodius atriceps, Niltava grandis, and Stachyris nigriceps. We accomplished relatively thorough sampling and data collection by sequencing ultraconserved elements (UCEs) using DNA extracted from modern and older (historical) specimens. We obtained a genome-wide set of 753–4,501 variable loci and 3,919–18,472 single nucleotide polymorphisms. The formation of major within-species lineages occurred within a similar span of time (0.5–1.5 mya). Major patterns in population genetic structure are largely consistent with the dispersal potential and habitat requirements of the study species. A population break across the Isthmus of Kra was shared only by the two hill/submontane insectivores (N. grandis and S. nigriceps). Across Sundaland, there is little structure in B. atriceps, which is a eurytopic and partially frugivorous species that often utilizes forest edges. Two other eurytopic species, A. longirostra and I. puella, possess highly divergent populations in peripheral Sunda Islands (Java and/or Palawan) and India. These species probably possess intermediate dispersal abilities that allowed them to colonize new areas, and then remained largely isolated subsequently. We also observed an east–west break in Indochina that was shared by B. atriceps and S. nigriceps, species with very different habitat requirements and dispersal potential. By analyzing high-throughput DNA data, our study provides an unprecedented comparative perspective on the process of avian population divergence across Southeast Asia, a process that is determined by geography, species characteristics, and the stochastic nature of dispersal and vicariance events

    Swelling strains from density measurements

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    Water in contact with silica glass surfaces diffuses into the glass, and reacts with the silica network under hydroxyl generation. Clear evidence has been reported in the literature for a volume swelling due to the water uptake and reaction in silica. In the past, the authors showed in a couple of papers the principle effects of volume swelling by hydroxyl generation on mechanics and fracture mechanics properties. From literature data on density as a function of water content a linear dependence of the volume swelling strain with water concentration was established. This dependency will be discussed in the present report including data scatter

    Group-finding with photometric redshifts: The Photo-z Probability Peaks algorithm

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    We present a galaxy group-finding algorithm, the Photo-z Probability Peaks (P3) algorithm, optimized for locating small galaxy groups using photometric redshift data by searching for peaks in the signal-to-noise of the local overdensity of galaxies in a three-dimensional grid. This method is an improvement over similar two-dimensional matched-filter methods in reducing background contamination through the use of redshift information, allowing it to accurately detect groups at lower richness. We present the results of tests of our algorithm on galaxy catalogues from the Millennium Simulation. Using a minimum S/N of 3 for detected groups, a group aperture size of 0.25 Mpc/h, and assuming photometric redshift accuracy of sigma_z = 0.05 it attains a purity of 84% and detects ~295 groups/deg.^2 with an average group richness of 8.6 members. Assuming photometric redshift accuracy of sigma_z = 0.02, it attains a purity of 97% and detects ~143 groups/deg.^2 with an average group richness of 12.5 members. We also test our algorithm on data available for the COSMOS field and the presently-available fields from the CFHTLS-Wide survey, presenting preliminary results of this analysis.Comment: Accepted for publication by MNRAS, 16 pages, 11 color figure

    Difference in details: transfer learning case study of "cryptic" plants and moths

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    Can we classify species of very similar looking organisms quickly and accurately using only out of the box feature transfer? What if we only have small number of images? This experimental paper is part of on-going project on species recognition research and evaluates transfer learning and fine-tuning approaches on two highly specialized fine-grained datasets. The two fine-grained datasets were specifically assembled for the purpose of this research. These datasets consist of images of New Zealand native species of moths and ”cryptic” plants of Genus Corposma found also in New Zealand. We compare results from finetuning experiments with performance of transfer learning without fine-tuning. The latter results are based on features extracted from various levels of depth in the InceptionV3 network, including fully connected layers. The extracted features serve as inputs to a number of classification algorithms. We observe contrasting results for the two datasets. For the dataset of moths, the method based on features extracted from deep levels of the InceptionV3 network outperforms fine-tuning in accuracy (90.09% versus 87.18%). This is not the case for the dataset of cryptic plants (60.46% versus 74.37%). Despite both datasets being fine-grained in nature, these experimental differences could be attributed to intrinsically different morphology of organisms and warrant further investigation

    The Dark Energy Survey Data Management System

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    The Dark Energy Survey collaboration will study cosmic acceleration with a 5000 deg2 griZY survey in the southern sky over 525 nights from 2011-2016. The DES data management (DESDM) system will be used to process and archive these data and the resulting science ready data products. The DESDM system consists of an integrated archive, a processing framework, an ensemble of astronomy codes and a data access framework. We are developing the DESDM system for operation in the high performance computing (HPC) environments at NCSA and Fermilab. Operating the DESDM system in an HPC environment offers both speed and flexibility. We will employ it for our regular nightly processing needs, and for more compute-intensive tasks such as large scale image coaddition campaigns, extraction of weak lensing shear from the full survey dataset, and massive seasonal reprocessing of the DES data. Data products will be available to the Collaboration and later to the public through a virtual-observatory compatible web portal. Our approach leverages investments in publicly available HPC systems, greatly reducing hardware and maintenance costs to the project, which must deploy and maintain only the storage, database platforms and orchestration and web portal nodes that are specific to DESDM. In Fall 2007, we tested the current DESDM system on both simulated and real survey data. We used Teragrid to process 10 simulated DES nights (3TB of raw data), ingesting and calibrating approximately 250 million objects into the DES Archive database. We also used DESDM to process and calibrate over 50 nights of survey data acquired with the Mosaic2 camera. Comparison to truth tables in the case of the simulated data and internal crosschecks in the case of the real data indicate that astrometric and photometric data quality is excellent.Comment: To be published in the proceedings of the SPIE conference on Astronomical Instrumentation (held in Marseille in June 2008). This preprint is made available with the permission of SPIE. Further information together with preprint containing full quality images is available at http://desweb.cosmology.uiuc.edu/wik

    The thermodynamic balance of the Weddell Gyre

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    The thermodynamic balance of the Weddell Gyre is assessed from an inverse estimate of the circulation across the gyre's rim. The gyre experiences a weak net buoyancy gain that arises from a leading-order cancellation between two opposing contributions, linked to two cells of water mass transformation and diapycnal overturning. The lower cell involves a cooling-driven densification of 8.4 ± 2.0 Sv of Circumpolar Deep Water and Antarctic Bottom Water near the gyre's southern and western margins. The upper cell entails a freshening-driven conversion of 4.9 ± 2.0 Sv of Circumpolar Deep Water into lighter upper-ocean waters within the gyre interior. The distinct role of salinity between the two cells stems from opposing salinity changes induced by sea ice production, meteoric sources and admixture of fresh upper-ocean waters in the lower cell, which contrasts with coherent reductions in salinity associated with sea ice melting and meteoric sources in the upper cell

    Angular Distribution of Auger Electrons Emitted through the Resonant Transfer and Excitation Process Following O⁵⁺+He Collisions

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    This Letter reports the first measurements of the angular distribution of Auger electrons emitted from the decay of the (1s2s2p2)3D O4+** doubly excited state formed predominantly through resonant transfer and excitation (RTE) in collisions of 13-MeV O5+ projectiles with He. The (1s2s2p2)3D angular distribution is strongly peaked along the beam direction, in agreement with recent calculations of the RTE angle-dependent impulse approximation. Furthermore, interference effects between the RTE and the elastic target direct-ionization channels are observed
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