1,095 research outputs found
Analytic solutions to the accretion of a rotating finite cloud towards a central object - II. Schwarzschild spacetime
We construct a general relativistic model for the accretion flow of a
rotating finite cloud of non-interacting particles infalling onto a
Schwarzschild black hole. The streamlines start at a spherical shell, where
boundary conditions are fixed, and are followed down to the point at which they
either cross the black hole horizon or become incorporated into an equatorial
thin disc. Analytic expressions for the streamlines and the velocity field are
given, in terms of Jacobi elliptic functions, under the assumptions of
stationarity and ballistic motion. A novel approach allows us to describe all
of the possible types of orbit with a single formula. A simple numerical scheme
is presented for calculating the density field. This model is the relativistic
generalisation of the Newtonian one developed by Mendoza, Tejeda, Nagel, 2009
and, due to its analytic nature, it can be useful in providing a benchmark for
general relativistic hydrodynamical codes and for exploring the parameter space
in applications involving accretion onto black holes when the approximations of
steady state and ballistic motion are reasonable ones.Comment: 12 pages, 6 figures, references and minor changes added to match
version accepted for publication in MNRA
De novo three-way chromosome translocation 46,XY,t(4;6;21)(p16;p21.1;q21) in a male with cleidocranial dysplasia
Cleidocranial dysplasia (CCD) is an autosomal dominant skeletal dysplasia associated with cranial, clavicular, and dental anomalies. It is caused by mutations in the RUNX2 gene, which encodes an osteoblast-specific transcription factor and maps to chromosome 6p21. We report clinical and molecular cytogenetic studies in a patient with clinical features of CCD including wormian bones, delayed fontanel closure, hypoplastic clavicles and pubic rami, and supernumerary dentition. Additional abnormalities of bone growth and connective tissue, including easy bruisability, scarring, bleeding, joint hypermobility, and developmental delay were also observed. Molecular cytogenetic studies identified a de novo apparently balanced three-way translocation 46,XY,t(4;6;21)(p16;p21.1;q21). Further mapping revealed the breakpoint on 6p21 to be ∼50 kb upstream of exon 1 of the RUNX2 gene, with RUNX2 being intact on the derivative chromosome 6. We hypothesize that the proband's CCD has arisen from disruption of the developmentally regulated gene RUNX2 at the 6p21 breakpoint, due to a position effect mutation which may have altered the expression of the gene. Further studies might unravel a new regulatory element for RUNX2
An analytic toy model for relativistic accretion in Kerr spacetime
We present a relativistic model for the stationary axisymmetric accretion
flow of a rotating cloud of non-interacting particles falling onto a Kerr black
hole. Based on a ballistic approximation, streamlines are described
analytically in terms of timelike geodesics, while a simple numerical scheme is
introduced for calculating the density field. A novel approach is presented for
describing all of the possible types of orbit by means of a single analytic
expression. This model is a useful tool for highlighting purely relativistic
signatures in the accretion flow dynamics coming from a strong gravitational
field with frame-dragging. In particular, we explore the coupling due to this
between the spin of the black hole and the angular momentum of the infalling
matter. Moreover, we demonstrate how this analytic solution may be used for
benchmarking general relativistic numerical hydrodynamics codes by comparing it
against results of smoothed particle hydrodynamics simulations for a
collapsar-like setup. These simulations are performed first for a ballistic
flow (with zero pressure) and then for a hydrodynamical one where we measure
the effects of pressure gradients on the infall, thus exploring the extent of
applicability of the ballistic approximation.Comment: 15 pages, 8 figures, references and minor changes added to match
version accepted for publication in MNRA
Inferring school district learning modalities during the COVID-19 pandemic with a hidden Markov model
In this study, learning modalities offered by public schools across the
United States were investigated to track changes in the proportion of schools
offering fully in-person, hybrid and fully remote learning over time. Learning
modalities from 14,688 unique school districts from September 2020 to June 2021
were reported by Burbio, MCH Strategic Data, the American Enterprise
Institute's Return to Learn Tracker and individual state dashboards. A model
was needed to combine and deconflict these data to provide a more complete
description of modalities nationwide.
A hidden Markov model (HMM) was used to infer the most likely learning
modality for each district on a weekly basis. This method yielded higher
spatiotemporal coverage than any individual data source and higher agreement
with three of the four data sources than any other single source. The model
output revealed that the percentage of districts offering fully in-person
learning rose from 40.3% in September 2020 to 54.7% in June of 2021 with
increases across 45 states and in both urban and rural districts. This type of
probabilistic model can serve as a tool for fusion of incomplete and
contradictory data sources in support of public health surveillance and
research efforts.Comment: 25 pages, 4 figure
The Early External Cephalic Version (ECV) 2 Trial: an international multicentre randomised controlled trial of timing of ECV for breech pregnancies
gravity constrained by PPN parameters and stochastic background of gravitational waves
We analyze seven different viable -gravities towards the Solar System
tests and stochastic gravitational waves background. The aim is to achieve
experimental bounds for the theory at local and cosmological scales in order to
select models capable of addressing the accelerating cosmological expansion
without cosmological constant but evading the weak field constraints. Beside
large scale structure and galactic dynamics, these bounds can be considered
complimentary in order to select self-consistent theories of gravity working at
the infrared limit. It is demonstrated that seven viable -gravities under
consideration not only satisfy the local tests, but additionally, pass the
above PPN-and stochastic gravitational waves bounds for large classes of
parameters.Comment: 23 pages, 8 figure
Statewide Systematic Evaluation of Sudden, Unexpected Infant Death Classification: Results from a National Pilot Project
The Centers for Disease Control and Prevention funded seven states, including Kentucky, to clarify statewide death certification practices in sudden, unexpected infant death and compare state performances with national expectations. Accurate assignment of the cause and manner of death in cases of sudden, unexpected infant death is critical for accurate vital statistics data to direct limited resources to appropriate targets, and to implement optimal and safe risk reduction strategies. The primary objectives are to (1) Compare SUID death certifications recommended by the KY medical examiners with the stated cause of death text field on the hard copy death electronic death certificates and (2) Compare KY and national SUID rates. Causes of death for SUID cases recommended by the medical examiners and those appearing on the hard copy and electronic death certificates in KY were collected retrospectively for 2004 and 2005. Medical examiner recommendations were based upon a classification scheme devised by them in 2003. Coroners hard copy death certificates and the cause of death rates in KY were compared to those occurring nationally. Eleven percent of infants dying suddenly and unexpectedly did not undergo autopsy during the study interval. The KY 2003 classification scheme for SIDS is at variance with the NICHD and San Diego SIDS definitions. Significant differences in causes of death recommended by medical examiners and those appearing on the hard copy and electronic death certificates were identified. SIDS rates increased in KY in contrast to decreasing rates nationally. Nationwide adoption of a widely used SIDS definition, such as that proposed in San Diego in 2004 as well as legislation by states to ensure autopsy in all cases of sudden unexpected infant death are recommended. Medical examiners’ recommendations for cause of death should appear on death certificates. Multidisciplinary pediatric death review teams prospectively evaluating cases before death certification is recommended. Research into other jurisdictions death certification process is encouraged
Predictors of unintended pregnancy in Kersa, Eastern Ethiopia, 2010
<p>Abstract</p> <p>Background</p> <p>In Ethiopia, little is known about pregnancy among rural women. Proper maternal health care depends on clear understanding of the reproductive health situation. The objective of this study was to identify predictors of unintended pregnancy in rural eastern Ethiopia.</p> <p>Methodology</p> <p>This study was part of pregnancy surveillance at Kersa Demographic Surveillance and Health Research Center, East Ethiopia. Pregnant women were assessed whether their current pregnancy was intended or not. Data were collected by lay interviewers using uniform questionnaire. Odds Ratio, with 95% confidence interval using multiple and multinomial logistic regression were calculated to detect level of significance.</p> <p>Results</p> <p>Unintended pregnancy was reported by 27.9% (578/2072) of the study subjects. Out of which, 440 were mistimed and 138 were not wanted. Unintended pregnancy was associated with family wealth status (OR 1.47; 95% CI 1.14, 1.90), high parity (7 +) (OR 5.18; 95% CI 3.31, 8.12), and a longer estimated time to walk to the nearest health care facility (OR 2.24; 95% CI: 1.49, 3.39).</p> <p>In the multinomial regression, women from poor family reported that their pregnancy was mistimed (OR 1.69; 95% CI 1.27, 2.25). The longer estimated time (80 + minutes) to walk to the nearest health care facility influenced the occurrence of mistimed pregnancy (OR 2.58; 95% CI: 1.65, 4.02). High parity (7+) showed a strong association to mistimed and unwanted pregnancies (OR 3.11; 95% CI 1.87, 5.12) and (OR 14.34; 95% CI 5.72, 35.98), respectively.</p> <p>Conclusions</p> <p>The economy of the family, parity, and walking distance to the nearest health care institution are strong predictors of unintended pregnancy. In order to reduce the high rate of unintended pregnancy Efforts to reach rural women with family planning services should be strengthened.</p
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