Prevalência de sobrepeso e obesidade em pacientes com Transtorno Bipolar na cidade de Salvador / Prevalence of overweight and obesity in patients with Bipolar Disorder in the city of Salvador

O objetivo foi apresentar a prevalência de sobrepeso e obesidade numa população de adultos com Transtorno Bipolar, em Salvador. Trata-se de um estudo observacional que analisou 181 pacientes, cuja prevalência conjunta de sobrepeso e obesidade foi de 67%. Sendo que homens apresentaram taxas de prevalência de sobrepeso e obesidade de 68,8%, com igual prevalência para as duas classificações e as mulheres apresentaram taxa de sobrepeso de 33,3% e obesidade de 36,7%, que somadas chegam a 70%

O cordel está na moda: a influência da Folkcomunicação nas criações da Moda contemporânea

Considerando que na sociedade contemporânea as manifestações das culturas populares estãosendo amplamente adaptadas, de modo a se tornarem produtos comercializáveis, o objetivo deste estudo propõe uma análise das adaptações e representações simbólicas da Literatura de Cordel dentro do universo comunicacional instituído pela criação de produtos ligados ao universo da Moda. É justificável investigar esse fenômeno através do olhar da Folkcomunicação, para entender os contextos e processos comunicativos que movem as reinterpretações e os significados adquiridos a partir dessa refuncionalização dos tradicionaisfolhetos nordestinos. Os estudos sobre Folkcomunicação, folkmarketing, imaginário, Literatura de Cordel e Moda fundamentam este artigo. Como objeto de estudo, verificamos cinco marcas, de diferentes regiões do país, do ramo de confecção de roupas e acessórios de Moda, que se utilizaram da Folkcomunicação para a criação de coleções de produtos mercadológicos, nos quais encontramos diferentes formas de representações do imaginário nordestino através das inspirações nos folhetos de Cordel. Observa-se que não se esgotam aspossibilidades de futuras investigações quanto ao objeto pesquisado

Social support and bipolar disorder

Background Bipolar disorder is a chronic condition that affects the functioning of its carriers in many different ways, even when treated properly. Therefore, it’s also important to identify the psychosocial aspects that could contribute to an improvement of this population’s quality of life.Objective Carry out a literature review on the role of social support in cases of bipolar disorder.Method A research on the following online databases PubMed, Lilacs and SciELO was conducted by using the keywords “social support” or “social networks” and “mood disorders” or “bipolar disorder” or “affective disorder,” with no defined timeline.Results Only 13 studies concerning the topic of social support and BD were found in the search for related articles. Generally speaking, the results show low rates of social support for BD patients.Discussion Despite the growing interest in the overall functioning of patients with bipolar disorder, studies on social support are still rare. Besides, the existing studies on the subject use different methodologies, making it difficult to establish data comparisons

The potential role of polyelectrolyte complex nanoparticles based on cashew gum, tripolyphosphate and chitosan for the loading of insulin

Polyelectrolytic complexation has stood out due to its application in the development of drug delivery systems using biopolymers as raw materials. The formation of complexes between cashew gum and chitosan can be intermediated by cross-links, mediated by the action of the sodium tripolyphosphate crosslinking agent. These polymers have been used in the nanotechnological development of formulations to protect peptide drugs, such as insulin, allowing their oral administration. In this work, we describe the development of polyelectrolytic complexes from cashew gum and chitosan as biopolymers for oral administration of insulin. The obtained complexes showed a mean particle size of 234 nm and polydispersity index of 0.2. The complexes were 234 nm in size, PDI 0.2, zeta potential 4.5 mV and 22% trapping. The obtained complexes demonstrated considerable and promising characteristics for use as oral insulin delivery systems.e Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco (FACEPE), Banco do Nordeste (grant FUNDECI/2016.0015), Portuguese Science and Technology Foundation (FCT/MCT) and from European Funds (PRODER/COMPETE) through the project UIDB/04469/2020 (strategic fund), co-financed by FEDER, under the Partnership Agreement PT2020info:eu-repo/semantics/publishedVersio

High anti-SARS-CoV-2 antibody seroconversion rates before the second wave in Manaus, Brazil, and the protective effect of social behaviour measures: results from the prospective DETECTCoV-19 cohort

Background: The city of Manaus, Brazil, has seen two collapses of the health system due to the COVID-19 pandemic. We report anti-SARS-CoV-2 nucleocapsid IgG antibody seroconversion rates and associated risk factors in Manaus residents before the second wave of the epidemic in Brazil. Methods: A convenience sample of adult (aged ≥18 years) residents of Manaus was recruited through online and university website advertising into the DETECTCoV-19 study cohort. The current analysis of seroconversion included a subgroup of DETECTCoV-19 participants who had at least two serum sample collections separated by at least 4 weeks between Aug 19 and Oct 2, 2020 (visit 1), and Oct 19 and Nov 27, 2020 (visit 2). Those who reported (or had no data on) having a COVID-19 diagnosis before visit 1, and who were positive for anti-SARS-CoV-2 nucleocapsid IgG antibodies at visit 1 were excluded. Using an in-house ELISA, the reactivity index (RI; calculated as the optical density ratio of the sample to the negative control) for serum anti-SARS-CoV-2 nucleocapsid IgG antibodies was measured at both visits. We calculated the incidence of seroconversion (defined as RI values ≤1·5 at visit 1 and ≥1·5 at visit 2, and a ratio >2 between the visit 2 and visit 1 RI values) during the study period, as well as incidence rate ratios (IRRs) through cluster-corrected and adjusted Poisson regression models to analyse associations between seroconversion and variables related to sociodemographic characteristics, health access, comorbidities, COVID-19 exposure, protective behaviours, and symptoms. Findings: 2496 DETECTCoV-19 cohort participants returned for a follow-up visit between Oct 19 and Nov 27, 2020, of whom 204 reported having COVID-19 before the first visit and 24 had no data regarding previous disease status. 559 participants were seropositive for anti-SARS-CoV-2 nucleocapsid IgG antibodies at baseline. Of the remaining 1709 participants who were seronegative at baseline, 71 did not meet the criteria for seroconversion and were excluded from the analyses. Among the remaining 1638 participants who were seronegative at baseline, 214 showed seroconversion at visit 2. The seroconversion incidence was 13·06% (95% CI 11·52–14·79) overall and 6·78% (5·61–8·10) for symptomatic seroconversion, over a median follow-up period of 57 days (IQR 54–61). 48·1% of seroconversion events were estimated to be asymptomatic. The sample had higher proportions of affluent and higher-educated people than those reported for the Manaus city population. In the fully adjusted and corrected model, risk factors for seroconversion before visit 2 were having a COVID-19 case in the household (IRR 1·49 [95% CI 1·21–1·83]), not wearing a mask during contact with a person with COVID-19 (1·25 [1·09–1·45]), relaxation of physical distancing (1·31 [1·05–1·64]), and having flu-like symptoms (1·79 [1·23–2·59]) or a COVID-19 diagnosis (3·57 [2·27–5·63]) between the first and second visits, whereas working remotely was associated with lower incidence (0·74 [0·56–0·97]). Interpretation: An intense infection transmission period preceded the second wave of COVID-19 in Manaus. Several modifiable behaviours increased the risk of seroconversion, including non-compliance with non-pharmaceutical interventions measures such as not wearing a mask during contact, relaxation of protective measures, and non-remote working. Increased testing in high-transmission areas is needed to provide timely information about ongoing transmission and aid appropriate implementation of transmission mitigation measures. Funding: Ministry of Education, Brazil; Fundação de Amparo à Pesquisa do Estado do Amazonas; Pan American Health Organization (PAHO)/WHO.World Health OrganizationRevisión por pare