The current deglaciation of the Ortles-Cevedale massif (Eastern Italian Alps): impacts, controls and degree of imbalance.

The Ortles-Cevedale is the largest glacierized mountain group of the Italian Alps hosting 112 ice bodies, with a total area of 76.8 km2. Since the 1980\u2019s, this massif is undergoing a rapid deglaciation, as most of the mountain ranges in the European Alps. The aims of this work were: i) to quantify area and volume change of the Ortles- Cevedale glacier system from the 1980s to the 2000s; ii) to improve the knowledge of factors controlling the spatial variability of the deglaciation; and iii) to assess the degree of imbalance of individual glaciers with respect to the present climate conditions. Two inventories were created, based on Landsat5 TM scenes of 20-09-1987 and 31-08-2009. Contrast-enhanced composites (bands TM5, TM4 and TM3), aerial photos and field surveys (for the most recent period) were used to correct the automatic delineation of glaciers derived from a hard classification based on a threshold applied to a TM3/TM5 ratio image. Since Landsat scenes were acquired at the end of the ablation seasons and fresh snow was absent, the accumulation areas could be roughly determined by mapping the snow covered area. This region was identified from the difference in reflectance between snow and ice in the near infrared band of Landsat (TM4), and mapped after correcting topographic effects to determine surface reflectance. The area-averaged geodetic mass budget was then calculated for the individual glaciers by differencing two Digital Terrain Models (2000s minus 1980s, derived from LiDAR and aerial photogrammetry) and combining the result with the glacier outlines. Afterwards, we examined the mass balance data using statistical analyses (Correlation matrices, Principal Component Analysis, Cluster Analysis). This allowed us highlighting clusters of glaciers, which exhibit a similar behavior, identify the outlayers and the relative influence of the factors controlling spatial variability of the mass losses. Finally, we assessed the degree of imbalance of individual glaciers by comparing the current Accumulation Area Ratios (AAR) with the balanced-budget AAR (AAR0), the latter also accounting for the debris cover of glaciers. We found that the total area loss of the Ortles-Cevedale glaciers from 1987 to 2009 amounts to 23.5 km2, i.e. 23.4% of the initial area. On the other hand, the AAR of the entire glacier system was 0.3 in both investigated years. The overall debris cover increased from 10.5% to 16.3%. The geodetic mass balance rate was -0.7 m w.e. y1(as an average on 112 ice bodies), ranging from -0.1 to -1.7 m w.e. y1. We also found that the main controls of the differing change of single glaciers are related to their hypsometry (elevation range and slope), AAR, feeding source and debris cover. Interestingly, a significant correlation was found between AAR, AAR0 and debris cover. This information was used to assess and visualize the needed additional reduction of individual glaciers to reach equilibrium with the current size of their accumulation areas. This amounts on average to a further reduction of 40% of the current areal extent of glaciers

The mass function dependence on the dynamical state of dark matter haloes

Galaxy clusters are luminous tracers of the most massive dark matter haloes in the Universe. To use them as a cosmological probe, a detailed description of the properties of dark matter haloes is required. We characterize how the dynamical state of haloes impacts the halo mass function at the high-mass end. We used the dark matter-only MultiDark suite of simulations and the high-mass objects M > 2.7e13 M/h therein. We measured mean relations of concentration, offset, and spin as a function of halo mass and redshift. We investigated the distributions around the mean relations. We measured the halo mass function as a function of offset, spin, and redshift. We formulated a generalized mass function framework that accounts for the dynamical state of the dark matter haloes. We confirm the discovery of the concentration upturn at high masses and provide a model that predicts the concentration for different values of mass and redshift with one single equation. We model the distributions around the mean concentration, offset, and spin with modified Schechter functions. The concentration of low-mass haloes shows a faster redshift evolution compared to high-mass haloes, especially in the high-concentration regime. The offset parameter is smaller at low redshift, in agreement with the relaxation of structures at recent times. The peak of its distribution shifts by a factor of 1.5 from z = 1.4 to z = 0. The individual models are combined into a comprehensive mass function model, as a function of spin and offset. Our model recovers the fiducial mass function with 3% accuracy at redshift 0 and accounts for redshift evolution up to z = 1.5. This approach accounts for the dynamical state of the halo when measuring the halo mass function. It offers a connection with dynamical selection effects in galaxy cluster observations. This is key toward precision cosmology using cluster counts as a probe.Comment: to be published in Astronomy&Astrophysic

Life in harsh environments : carabid and spider trait types and functional diversity on a debris-covered glacier and along its foreland

1. Patterns of species richness and species assemblage composition of ground-dwelling arthropods in primary successions along glacier forelands are traditionally described using a taxonomic approach. On the other hand, the functional trait approach could ensure a better characterisation of their colonisation strategies in these types of habitat. 2. The functional trait approach was applied to investigate patterns of functional diversity and life-history traits of ground beetles and spiders on an alpine debris-covered glacier and along its forefield in order to describe their colonisation strategies. 3. Ground beetles and spiders were sampled at different successional stages, representing five stages of deglaciation. 4. The results show that the studied glacier hosts ground beetle and spider assemblages that are mainly characterised by the following traits: walking colonisers, ground hunters and small-sized species. These traits are typical of species living in cold, wet, and gravelly habitats. The diversity of functional traits in spiders increased along the succession, and in both carabids and spiders, life-history traits follow the \u2018addition and persistence model\u2019. Accordingly, there is no turnover but there is an addition of new traits and a variation in their proportion within each species assemblage along the succession. The distribution of ground beetles and spiders along the glacier foreland and on the glacier seems to be driven by dispersal ability and foraging strategy. 5. The proposed functional approach improves knowledge of the adaptive strategies of ground-dwelling arthropods colonising glacier surfaces and recently deglaciated terrains, which represent landforms quickly changing due to global warming

Impact of Po Valley emissions on the highest glacier of the Eastern European Alps

Abstract. In June 2009, we conducted the first extensive glaciological survey of Alto dell'Ortles, the uppermost glacier of Mt. Ortles (3905 m a.s.l.), the highest summit of the Eastern European Alps. This section of the Alps is located in a rain shadow and is characterized by the lowest precipitation rate in the entire Alpine arc. Mt. Ortles offers a unique opportunity to test deposition mechanisms of chemical species that until now were studied only in the climatically-different western sector. We analyzed snow samples collected on Alto dell'Ortles from a 4.5 m snow-pit at 3830 m a.s.l., and we determined a large suite of trace elements and ionic compounds that comprise the atmospheric deposition over the past two years. Trace element concentrations measured in snow samples are extremely low with mean concentrations at pg g−1 levels. Only Al and Fe present median values of 1.8 and 3.3 ng g−1, with maximum concentrations of 21 and 25 ng g−1. The median crustal enrichment factor (EFc) values for Be, Rb, Sr, Ba, U, Li, Al, Ca, Cr, Mn, Fe, Co, Ga and V are lower than 10 suggesting that these elements originated mainly from soil and mineral aerosol. EFc higher than 100 are reported for Zn (118), Ag (135), Bi (185), Sb (401) and Cd (514), demonstrating the predominance of non-crustal depositions and suggesting an anthropogenic origin. Our data show that the physical stratigraphy and the chemical signals of several species were well preserved in the uppermost snow of the Alto dell'Ortles glacier. A clear seasonality emerges from the data as the summer snow is more affected by anthropogenic and marine contributions while the winter aerosol flux is dominated by crustal sources. For trace elements, the largest mean EFc seasonal variations are displayed by V (with a factor of 3.8), Sb (3.3), Cu (3.3), Pb (2.9), Bi (2.8), Cd (2.1), Zn (1.9), Ni (1.8), Ag (1.8), As (1.7) and Co (1.6). When trace species ratios in local and Po Valley emissions are compared with those in Alto dell'Ortles snow, the deposition on Mt. Ortles is clearly linked with Po Valley summer emissions. Despite climatic differences between the Eastern and Western Alps, trace element ratios from Alto dell'Ortles are comparable with those obtained from high-altitude glaciers in the Western Alps, suggesting similar sources and transport processes at seasonal time scales in these two distinct areas. In particular, the large changes in trace element concentrations both in the Eastern and Western Alps appear to be more related to the regional vertical structure of the troposphere rather than the synoptic weather patterns

O Corona, where art thou? eROSITA's view of UV-optical-IR variability-selected massive black holes in low-mass galaxies

Finding massive black holes (MBHs, $M_{BH}\approx10^4-10^7 M_{\odot}$) in the nuclei of low-mass galaxies ($M_{*}\lessapprox10^{10} M_{\odot}$) is crucial to constrain seeding and growth of black holes over cosmic time, but it is particularly challenging due to their low accretion luminosities. Variability selection via long-term photometric ultraviolet, optical, or infrared (UVOIR) light curves has proved effective and identifies lower-Eddington ratios compared to broad and narrow optical spectral lines searches. In the inefficient accretion regime, X-ray and radio searches are effective, but they have been limited to small samples. Therefore, differences between selection techniques have remained uncertain. Here, we present the first large systematic investigation of the X-ray properties of a sample of known MBH candidates in dwarf galaxies. We extracted X-ray photometry and spectra of a sample of $\sim200$ UVOIR variability-selected MBHs and significantly detected 17 of them in the deepest available \emph{SRG}/eROSITA image, of which four are newly discovered X-ray sources and two are new secure MBHs. This implies that tens to hundreds of LSST MBHs will have SRG/eROSITA counterparts, depending on the seeding model adopted. Surprisingly, the stacked X-ray images of the many non-detected MBHs are incompatible with standard disk-corona relations, typical of active galactic nuclei, inferred from both the optical and radio fluxes. They are instead compatible with the X-ray emission predicted for normal galaxies. After careful consideration of potential biases, we identified that this X-ray weakness needs a physical origin. A possibility is that a canonical X-ray corona might be lacking in the majority of this population of UVOIR-variability selected low-mass galaxies or that unusual accretion modes and spectral energy distributions are in place for MBHs in dwarf galaxies.Comment: Accepted for publication in A&

The role of high-field magnetic resonance imaging in parkinsonian disorders:Pushing the boundaries forward

Historically, magnetic resonance imaging (MRI) has contributed little to the study of Parkinson's disease (PD), but modern MRI approaches have unveiled several complementary markers that are useful for research and clinical applications. Iron- and neuromelanin-sensitive MRI detect qualitative changes in the substantia nigra. Quantitative MRI markers can be derived from diffusion weighted and iron-sensitive imaging or volumetry. Functional brain alterations at rest or during task performance have been captured with functional and arterial spin labeling perfusion MRI. These markers are useful for the diagnosis of PD and atypical parkinsonism, to track disease progression from the premotor stages of these diseases and to better understand the neurobiological basis of clinical deficits. A current research goal using MRI is to generate time-dependent models of the evolution of PD biomarkers that can help understand neurodegeneration and provide reliable markers for therapeutic trials. This article reviews recent advances in MRI biomarker research at high-field (3T) and ultra high field-imaging (7T) in PD and atypical parkinsonism. © 2017 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society

Pain in Multiple System Atrophy a Systematic Review and Meta-Analysis

Background: Individuals with multiple system atrophy (MSA) often complain about pain, nonetheless this remains a poorly investigated non-motor feature of MSA. Objectives: Here, we aimed at assessing the prevalence, characteristics, and risk factors for pain in individuals with MSA. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) guidelines, we systematically screened the PubMED, Cochrane, and Web of Science databases for papers published in English until September 30, 2022, combining the following keywords: “pain,” “multiple system atrophy,” “MSA,” “olivopontocerebellar atrophy,” “OPCA,” “striatonigral degeneration,” “SND,” “Shy Drager,” and “atypical parkinsonism.”. Results: The search identified 700 records. Sixteen studies provided information on pain prevalence in cohorts of MSA individuals and were included in a qualitative assessment based on the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) tool. Thirteen studies (11 cross-sectional, two longitudinal) scored ≥14 points on QUADAS assessment and were included in a quantitative analysis, pooling data from 1236 MSA individuals. The resulting pooled prevalence of pain in MSA was 67% (95% confidence intervals [CI] = 57%–75%), and significantly higher in individuals with MSA of parkinsonian rather than cerebellar type (76% [95% CI = 63%–87%] vs. 45% [95% CI = 33%–57%], P = 0.001). Pain assessment tools and collected information were highly heterogeneous across studies. Two studies reported pain treatment strategies and found that only every second person with MSA complaining about pain had received targeted treatment. Conclusions: We found that pain is a frequent, but still under-recognized and undertreated feature of MSA. Further research is needed to improve pain detection and treatment in MSA

Development and Validation of Automated Magnetic Resonance Parkinsonism Index 2.0 to Distinguish Progressive Supranuclear Palsy-Parkinsonism From Parkinson's Disease

Background: Differentiating progressive supranuclear palsy-parkinsonism (PSP-P) from Parkinson's disease (PD) is clinically challenging. Objective: This study aimed to develop an automated Magnetic Resonance Parkinsonism Index 2.0 (MRPI 2.0) algorithm to distinguish PSP-P from PD and to validate its diagnostic performance in two large independent cohorts. Methods: We enrolled 676 participants: a training cohort (n = 346; 43 PSP-P, 194 PD, and 109 control subjects) from our center and an independent testing cohort (n = 330; 62 PSP-P, 171 PD, and 97 control subjects) from an international research group. We developed a new in-house algorithm for MRPI 2.0 calculation and assessed its performance in distinguishing PSP-P from PD and control subjects in both cohorts using receiver operating characteristic curves. Results: The automated MRPI 2.0 showed excellent performance in differentiating patients with PSP-P from patients with PD and control subjects both in the training cohort (area under the receiver operating characteristic curve [AUC] = 0.93 [95% confidence interval, 0.89–0.98] and AUC = 0.97 [0.93–1.00], respectively) and in the international testing cohort (PSP-P versus PD, AUC = 0.92 [0.87–0.97]; PSP-P versus controls, AUC = 0.94 [0.90–0.98]), suggesting the generalizability of the results. The automated MRPI 2.0 also accurately distinguished between PSP-P and PD in the early stage of the diseases (AUC = 0.91 [0.84–0.97]). A strong correlation (r = 0.91, P < 0.001) was found between automated and manual MRPI 2.0 values. Conclusions: Our study provides an automated, validated, and generalizable magnetic resonance biomarker to distinguish PSP-P from PD. The use of the automated MRPI 2.0 algorithm rather than manual measurements could be important to standardize measures in patients with PSP-P across centers, with a positive impact on multicenter studies and clinical trials involving patients from different geographic regions. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society

Diffusion tensor imaging of Parkinson's disease, multiple system atrophy and progressive supranuclear palsy: a tract-based spatial statistics study

Although often clinically indistinguishable in the early stages, Parkinson's disease (PD), Multiple System Atrophy (MSA) and Progressive Supranuclear Palsy (PSP) have distinct neuropathological changes. The aim of the current study was to identify white matter tract neurodegeneration characteristic of each of the three syndromes. Tract-based spatial statistics (TBSS) was used to perform a whole-brain automated analysis of diffusion tensor imaging (DTI) data to compare differences in fractional anisotropy (FA) and mean diffusivity (MD) between the three clinical groups and healthy control subjects. Further analyses were conducted to assess the relationship between these putative indices of white matter microstructure and clinical measures of disease severity and symptoms. In PSP, relative to controls, changes in DTI indices consistent with white matter tract degeneration were identified in the corpus callosum, corona radiata, corticospinal tract, superior longitudinal fasciculus, anterior thalamic radiation, superior cerebellar peduncle, medial lemniscus, retrolenticular and anterior limb of the internal capsule, cerebral peduncle and external capsule bilaterally, as well as the left posterior limb of the internal capsule and the right posterior thalamic radiation. MSA patients also displayed differences in the body of the corpus callosum corticospinal tract, cerebellar peduncle, medial lemniscus, anterior and superior corona radiata, posterior limb of the internal capsule external capsule and cerebral peduncle bilaterally, as well as the left anterior limb of the internal capsule and the left anterior thalamic radiation. No significant white matter abnormalities were observed in the PD group. Across groups, MD correlated positively with disease severity in all major white matter tracts. These results show widespread changes in white matter tracts in both PSP and MSA patients, even at a mid-point in the disease process, which are not found in patients with PD