Bringing Dying Back Home? : Northern Finns’ End-of-Life Preparations, Concerns and Care Preferences and Finnish Care Policy’s Emphasis on Care at Home

In recent years, Finnish care policy has emphasised that older people should remain at home for as long as possible. Since the final stages of life and death will theoretically happen more often in the home, it is important to identify people’s experiences and needs regarding end-of-life care and dying. The aim of this article is to provide knowledge on these questions from the perspective of the Northern Finnish people (N = 294). Statistical analysis was used with data gathered from a survey of a random sample. People’s wishes for their end-of-life place and carers and their end-of-life plans and concerns, are analysed as part of a social and cultural construction of dying and end-of-life care. The results show that people do have end-of-life concerns and that they consider end-of-life planning important but that few preparations are actually made. In many instances, home is regarded as the best place for end-of-life care and dying, but care institutions are also regarded positively. Reliance on professional care is very strong, even though people hope to receive care from family members as well. The results are discussed in the light of Finnish care policy and end-of-life culture.Peer reviewe

Kuminaöljy estää perunaruttoa

Laboratoriossa kuminaöljy esti perunaruttosienen eri kehitysvaiheiden kasvun lähes täydellisesti. Öljy vaikutti myös itse perunan kasvuun ja kehittymiseen. Öljyllä käsitellyt kasvit tuottivat runsaasti ja samankokoisia mukuloita. Yllättäen kuminaöljy näyttääkin toimivan myös systeemisesti eli se voi kulkeutua myös itse kasvin sisälle. Lisäksi saatiin viitteitä kuminaöljyn vaikutuksesta perunan geeneihin.vokKA

Regional Variation in Restorative Treatment Need among Finnish Young People

Publisher Copyright: © 2021 Saujanya Karki et al.Aim. To evaluate the regional variation in restorative treatment need among Finnish young people based on the socioeconomic factors. Materials and Methods. This cross-sectional study was conducted in 20 garrisons of the Finnish Defence Forces in January and July 2011. The study population comprised 13,819 Finnish conscripts born in the beginning of 1990s, including females. A computer-based survey was done together with clinical oral examination to gather background information, e.g., educational status. Furthermore, average annual income of the conscript's residence municipality was achieved from the Statistics of Finland. The zip code of the place of residence of each conscript was later extracted from the Mildoc® system. Georeferenced place of residence and income status were merged as information on provinces' level in a dataset. The association between the outcome variable and explanatory variables was determined by using the generalized linear mixed model, and geomaps were constructed. Results. Mean D value was 1.41 ranging from 0.89 (Kymenlaakso) to 2.33 (Kainuu). Higher education and high-income level were protective factors for restorative treatment need. Restorative treatment need was also low in those areas with high (OR: 0.70, 95% CI: 0.56-0.87) and medium (OR: 0.79, 95% CI: 0.70-0.89) yearly income compared to low yearly income. The high odds for the need of restorative treatment were discovered in Northern Ostrobothnia (OR: 2.26, 95% CI: 1.53-3.33) followed by Central Ostrobothnia (OR: 2.08, 95% CI: 1.17-3.70), Uusimaa (OR: 1.55, 95% CI: 1.16-2.08), and Central Finland (OR: 1.54, 95% CI: 1.10-2.16) compared to Varsinais-Suomi. Conclusion. In conclusion, there is a significant regional variation in restorative treatment need among Finnish young people in their twenties based on the socioeconomic factors.Peer reviewe

Symptoms and diagnostic delays in bladder cancer with high risk of recurrence : results from a prospective FinnBladder 9 trial

Purpose To investigate the symptoms and delays in the clinical pathway of bladder cancer (BC). Methods This is a substudy of a prospective, randomized, multicenter phase III study (FinnBladder 9, NCT01675219) where the efficacy of photodynamic diagnosis and 6 weekly optimized mitomycin C instillations are studied in pTa bladder cancer with high risk for recurrence. The data of presenting symptoms and critical time points were prospectively collected, and the effect of factors on delays was analyzed. Results At the time of analysis, 245 patients were randomized. Analysis included 131 patients with primary bladder cancer and their complete data. Sixty-nine percent had smoking history and 67% presented with macroscopic hematuria. Median patient delay (from symptoms to health-care contact) was 7 days. The median general practice delay (from health-care contact to urology referral) was 8 days. Median time from urology referral to cystoscopy was 23 days and from cystoscopy to TUR-BT 21 days. Total time used in the clinical pathway (from symptom to TUR-BT) was 78 days. Current and former smokers had non-significantly shorter patient-related and general practice delays compared to never smokers. TUR-BT delay was significantly shorter in patients with malignant cytology (16 days) compared to patients with benign cytology (21 days, p = 0.03). Conclusions Patient-derived delay was short and most of the delay occurred in the referral centers. The majority had macroscopic hematuria as the initial symptom. Surprisingly, current and past smokers were more prone to contact the health-care system compared to never smokers.Peer reviewe

Intraoperative complications in kidney tumor surgery : critical grading for the European Association of Urology intraoperative adverse incident classification

Introduction The European Association of Urology committee in 2020 suggested a new classification, intraoperative adverse incident classification (EAUiaiC), to grade intraoperative adverse events (IAE) in urology. Aims We applied and validated EAUiaiC, for kidney tumor surgery. Patients and methods A retrospective multicenter study was conducted based on chart review. The study group comprised 749 radical nephrectomies (RN) and 531 partial nephrectomies (PN) performed in 12 hospitals in Finland during 2016-2017. All IAEs were centrally graded for EAUiaiC. The classification was adapted to kidney tumor surgery by the inclusion of global bleeding as a transfusion of >= 3 units of blood (Grade 2) or as >= 5 units (Grade 3), and also by the exclusion of preemptive conversions. Results A total of 110 IAEs were recorded in 13.8% of patients undergoing RN, and 40 IAEs in 6.4% of patients with PN. Overall, bleeding injuries in major vessels, unspecified origin and parenchymal organs accounted for 29.3, 24.0, and 16.0% of all IEAs, respectively. Bowel (n = 10) and ureter (n = 3) injuries were rare. There was no intraoperative mortality. IAEs were associated with increased tumor size, tumor extent, age, comorbidity scores, surgical approach and indication, postoperative Clavien-Dindo (CD) complications and longer stay in hospital. 48% of conversions were reactive with more CD-complications after reactive than preemptive conversion (43 vs. 25%). Conclusions The associations between IAEs and preoperative variables and postoperative outcome indicate good construct validity for EAUiaiC. Bleeding is the most important IAE in kidney tumor surgery and the inclusion of transfusions could provide increased objectivity.Peer reviewe

Acknowledging geodiversity in safeguarding biodiversity and human health

Our existence on Earth is founded on a vital nature, which supports human physical and mental health. However, nature is often depicted only through biodiversity, whereas geodiversity—the diversity of non-living nature—has so far been neglected. Geodiversity consists of assemblages, structures, and systems of geological, geomorphological, soil, and hydrological components that fundamentally underlie biodiversity. Biodiversity can support overall human health only with the foundation of geodiversity. Landscape characteristics, such as varying topography or bodies of water, promote aesthetic and sensory experiences and are also a product of geodiversity. In this Personal View, we introduce the concept of geodiversity as a driver for planetary health, describe its functions and services, and outline the intricate relationships between geodiversity, biodiversity, and human health. We also propose an agenda for acknowledging the importance of geodiversity in health-related research and decision making. Geodiversity is an emerging topic with untapped potential for ensuring ecosystem functionality and good living conditions for people in a time of changing environments

Report of the Selenium Working Group 2022

In Finland selenium has been added to compound fertilizers since 1984. In the background of this action were studies of the low selenium contents of domestic foods and feeds and concern about its negative effects for public health. Climatic and soil conditions increase the conversion of selenium into forms unavailable to plants and selenium fertilization is needed annually to maintain adequate selenium levels in domestic foods and feeds. During the growing season plants convert inorganic fertilizer selenium into organic selenium compounds that humans and animals can utilize more efficiently than inorganic selenium. Already in the growing season 1985 the effects of selenium supplemented fertilization were seen in domestic foods and feeds. Selenium contents increased 3–4-fold. With fertilization selenium concentrations in foods have been at adequate level to maintain the selenium adequate intake which is in accordance with recommendations. Additional selenium supplements are not needed. Selenium intake can be regulated by the amount of selenium in fertilizers (changed in 1990, 1998, 2007, 2013). Reasons behind these revisions were the changes in fertilization practises. Recent years interest towards bio-based fertilizers (BBFs) have increased due to both environmental and economic reasons. Fertilizing Products Regulation provides means for free movement of BBFs within the EU and a way to reduce EU:s dependency on imported mineral fertilizers. Due to various sources of materials for producing BBFs concentrations of selenium varies as well. However, bioavailability of selenium was poor. Changes in the selenium contents of fertilizers affect directly to the selenium intake of the population and selenium concentrations in human serum. 2010s selenium intake was about 0.08 mg/day/10 MJ and the serum selenium level 1.5 µmol/l. Both intake and serum selenium are at good and adequate level. Soluble selenium concentration in cultivated soils has remained about the same low level during the past 37 years despite annual application of selenium supplemented fertilizers. This is probably due to small annual application rates of selenium and its binding to insoluble form and thus requiring annual application to ensure adequate selenium uptake by plants. Selenium fertilization has not affected into amount of soluble selenium in cultivated soils during the 36 years of selenium fertilization. The input through fertilizers is small and during the growing season selenium is transferred into insoluble forms and binds into soil constituents. The selenium concentrations in surface waters and fishes have been at acceptable level. During floods and heavy rains soil erosion can increase selenium input somewhat, but generally selenium fertilization has not affected surface waters or any other environment. However, environmental issues should be followed regular basis

Koti, hyvinvointityö ja haavoittuvuus

In this book [titled Home, welfare work and vulnerability] the authors take the reader on welfare workers’ home visits to clients in need of support in their living. Welfare workers refer to professionals in health and social care who in the book are represented among others by social workers, social care workers and nurses. The main concepts of the book are home, welfare work and vulnerability and these are contemplated from different angles. Welfare work entails encountering people who are in vulnerable situations in the midst of their everyday lives. They may need support in coping with their mental health, with physical illnesses, with the challenges of achieving sobriety and recovery or perhaps with the difficulties accompanying old age. On the one hand their ability to act is limited and weak but on the other they have many kinds of strengths and resources. The book addresses a significant turning point in welfare services and work at which the objective is defined as the right of every individual to their own home and making living at home feasible for as long as possible. In the last fifty years or so many societal factors have made possible the dismantling of institutions, the reduction of places and the shortening of stays in institutions, the further development of care in the community, the construction of small residential and care facilities and most recently the further development of services to be taken into people’s homes. The last stage of this dismantling of institutions is referred to in the book as the “home turn”. As a societal change the home turn is complex – and that is how it is approached in the book. When one’s own home is the main place in which welfare policy and work are implemented, it is important to scrutinize more closely what actually occurs there and what special issues are connected to this given context. The book offers a timely point of view on the development of welfare services and the grass-root level welfare work done in the homes. It draws on interaction research based on ethnomethodology and human geography. Research data consist of recordings of home visits, researcher’s field diaries and interviews with clients and workers. The work includes both chapters providing conceptual and theoretical overviews and empirical research on the encounters between client and worker(s) on home visits. Welfare work accomplished in people’s homes entails many tensions and ethical issues which are analysed in the book and made visible through the means of research

Individualised non-contrast MRI-based risk estimation and shared decision-making in men with a suspicion of prostate cancer : Protocol for multicentre randomised controlled trial (multi-IMPROD V.2.0)

Introduction European Association of Urology and UK National Institute for Health and Care Excellence guidelines recommend that all men with suspicions of prostate cancer should undergo prebiopsy contrast enhanced, that is, multiparametric prostate MRI. Subsequent prostate biopsies should also be performed if MRI is positive, that is, Prostate Imaging-Reporting and Data System (PI-RADS) scores 3-5. However, several retrospective post hoc analyses have shown that this approach still leads to many unnecessary biopsy procedures. For example, 88%-96% of men with PI-RADS, three findings are still diagnosed with clinically non-significant prostate cancer or no cancer at all. Methods and analysis This is a prospective, randomised, controlled, multicentre trial, being conducted in Finland, to demonstrate non-inferiority in clinically significant cancer detection rates among men undergoing prostate biopsies post-MRI and men undergoing prostate biopsies post-MRI only after a shared decision based on individualised risk estimation. Men without previous diagnosis of prostate cancer and with abnormal digital rectal examination findings and/or prostate-specific antigen between 2.5 ug/L and 20.0 ug/L are included. We aim to recruit 830 men who are randomised at a 1:1 ratio into control (all undergo biopsies after MRI) and intervention arms (the decision to perform biopsies is based on risk estimation and shared decision-making). The primary outcome of the study is the proportion of men with clinically significant prostate cancer (Gleason 4+3 prostate cancer or higher). We will also compare the overall biopsy rate, benign biopsy rate and the detection of non-significant prostate cancer between the two study groups. Ethics and dissemination The study (protocol V.2.0, 4 January 2021) was approved by the Ethics Committee of the Hospital District of Southwest Finland (IORG number: 0001744, IBR number: 00002216; trial number: 99/1801/2019). Participants are required to provide written informed consent. Full reports of this study will be submitted to peer-reviewed journals, mainly urology and radiology. Trial registration number NCT04287088; the study is registered at ClinicalTrials.gov.publishedVersionPeer reviewe