Acute alcohol consumption is associated with increased interatrial electromechanical delay in healthy men

Background: Acute alcohol consumption can cause atrial fibrillation in patients with, and without, heart disease. Increased atrial electromechanical delay (EMD) has been associated with atrial fibrillation. We evaluated the atrial conduction properties by tissue Doppler imaging (TDI) echocardiography in healthy men following acute alcohol intake. Methods: Thirty healthy male volunteers were included in this study. Baseline ECG, heart rate, blood pressure, and TDI echocardiographic findings were compared to readings taken one hour after drinking six 12-oz cans of beer (76.8 g of ethanol). Results: Although the blood pressure and heart rate remained similar before and one hour after alcohol intake, Pmax and Pd values were significantly prolonged (114.2 &#177; 10.4 vs 100.8 &#177; 10.6, p = 0.002; 50.6 &#177; 9.6 vs 34.5 &#177; 8.8, p < 0.0001). Interatrial EMD was significantly increased after drinking alcohol compared to the baseline (19.8 &#177; 9.2 vs 14.0 &#177; 5.5 ms, p < 0.0002). Conclusions: Acute moderate alcohol intake was associated with an increased interatrial EMD obtained by TDI echocardiography. This finding may help explain how these patients express increased susceptibility to atrial fibrillation. (Cardiol J 2011; 18, 6: 682&#8211;686

SOME AZO DYES CONTAINING EUGENOL AND GUAIACOL, SYNTHESIS, ANTIOXIDANT CAPACITY, UREASE INHIBITORY PROPERTIES AND ANTI-HELICOBACTER PYLORI ACTIVITY

Sasmaz, Selami/0000-0001-5311-7550; kantar, cihan/0000-0002-5234-0782WOS: 000442387600004There are many studies about azo compounds at literature. However, antioxidant capacity, urease inhibitory and anti-Helicobacter pylori activity properties are not well known. Therefore, some azo dyes containing eugenol and guaiacol were synthesized by coupling reactions of different amines with eugenol and guaiacol, respectively. the newly synthesized compounds were screened for their antioxidant properties by employing three in vitro assays like 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay and CUPric Reducing Antioxidant Capacity (CUPRAC). All compounds were assayed for inhibitory effect against urease and Helicobacter pylori growth in vitro. These results suggest that compounds 1, 5, 6 and 7 can be novel urease inhibitory and anti-Helicobacter pylori agent.Recep Tayyip Erdogan University Scientific Research Project Units [2015.53007.102.02.02]This study was supported by the Recep Tayyip Erdogan University Scientific Research Project Units (Project No: 2015.53007.102.02.02)

A Combination of Heart Rate-Corrected QT Interval and GRACE Risk Score Better Predict Early Mortality in Patients with Non-ST Segment Elevation Acute Coronary Syndrome

Objective: This study aimed to evaluate whether the addition of heart rate-corrected QT interval prolongation to the Global Registry of Acute Coronary Events risk score improves the predictive value for early mortality in patients with non-ST segment elevation acute coronary syndrome

33 Questions about Triglycerides and Cardiovascular Effects: Expert Answers

Education professionals are concerned about the dropping levels of motivation and engagement students experience as they go through schooling. Sustained low motivation across the student population leads to increased dropout rates, which in turn leads to many detrimental consequences. The literature shows clear correlations between low self-efficacy and low motivation, alongside a lack of tools to address the problem. This thesis tested a student-centered intervention composed of a goal setting instrument, an expressive writing instrument, and several coping mechanisms. Self-efficacy was tested in eight 16-year-old Finnish students before and after the intervention using a validated self-efficacy scale. A thematic analysis was conducted to assess the importance and effects of each of the components of the intervention, and to account for external variables. All the participants showed an increase in self-efficacy after the intervention, which was attributed to be the main cause. The goal setting instrument was reported to have the strongest effect on self-efficacy, followed by the expressive writing instrument. The coping mechanisms showed null effects. The results suggest that the goal setting instrument causes new appraisals of the most influential source of self-efficacy: performance attainments. Additionally, expressive writing serves as a foundational previous step to goal setting. However, further research is required to confirm the validity of these findings. The small sample size, the strong localization, and the fact that self-efficacy is not directly observable, severely limit the results of the study. In addition, a longer study should be conducted to observe the durability of the effects of the intervention

33 Questions about Triglycerides and Cardiovascular Effects: Expert Answers

WOS: 000396440800002PubMed ID: 2844673