Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.

Numerous genetic loci have been associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans. We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N = 74,064) and follow-up studies (N = 48,607), we identified at genome-wide significance (P = 2.7 × 10(-8) to P = 2.3 × 10(-13)) four new PP loci (at 4q12 near CHIC2, 7q22.3 near PIK3CG, 8q24.12 in NOV and 11q24.3 near ADAMTS8), two new MAP loci (3p21.31 in MAP4 and 10q25.3 near ADRB1) and one locus associated with both of these traits (2q24.3 near FIGN) that has also recently been associated with SBP in east Asians. For three of the new PP loci, the estimated effect for SBP was opposite of that for DBP, in contrast to the majority of common SBP- and DBP-associated variants, which show concordant effects on both traits. These findings suggest new genetic pathways underlying blood pressure variation, some of which may differentially influence SBP and DBP

First-generation Turkish women in the 2060 neighbourhood of Antwerp. Creating places for interpersonal connection

status: In preparatio

Action research with an artistic turn: the “Welcome (W)all – MURO” project for youth in Alta de Lisboa.

In deze ppt presentatie voor een groep studenten 'Sociaal Werk' aan de Artevelde Hogeschool, Gent, beschrijf ik het participatieve actie onderzoek project ‘Welcome (W)all- MURO’ in de wijk Alto do Lumiar. Alto do Lumiar is een precaire wijk van Lumiar, in het noorden van Lissabon. De studenten zijn op studiereis in Lissabon, onder begeleiding van docent Peter Van Mullem. Het Welcome (W)all – MURO onderzoeksproject werd ondernomen in het kader van mijn doctoraat. Onderwerp van het doctoraat is de invloed van de materiële (publieke) ruimte op interpersoonlijke (samenwerkings)processen. Het project vond plaats in de periode augustus 2016 – april 2017. Het balanceert op de grens van verschillende disciplines: sociaal werk, artistiek/ ambachtelijk werk, antropologie, geografie, sociale innovatie,…en werkt rond het concept ‘erkenning’. Een van de belangrijkste doelen van het project is het ontwikkelen van een creatieve methode die de grenzen van samenwerking aftast in een gegeven socio-ruimtelijke context. In hoeverre is samenwerken mogelijk en welke samenwerking is mogelijk bij de creatie van een participatieve publieke muurschildering met jongeren? Op welke wijzen komt erkenning van de jongere aan bod?status: publishe

Place as a ‘social connector’: the link with a collaborative art process

The Flemish landscape is evolving rapidly. Our built environment changes at an ever faster pace and our social environment is becoming more and more diverse. We live, work or study with people from completely different backgrounds, both socially and geographically. However, not everyone is capable of handling those changes positively. An upsurge of social polarization incites aggression towards what or who deviates from what is previously seen as ‘mainstream’. IM Mount Murals contributes to improving interpersonal connection in neighborhoods by applying embodied artistic experiences in the public sphere. The process aims for embodied social (self) empowerment in the public sphere. By using art as a process, it seeks to realize or deepen positive interpersonal relationships, embedded in a particular public sphere. Actively experiencing is central to the process: feeling, smelling, remembering and listening to what is going on in a place, experiencing different materials while working with them and being aware of body language that plays between participants. Herewith, the process contributes to creating appreciation for one's own environment and associated social relationships, which in turn stimulates the process of sense of place (sense of place) and sense of belonging. Both processes are considered to be important conditions for dealing with our increasingly diverse society in a respectful manner.status: publishe

The Welcome (W)all - MURO, an interview by Claquete, Lisbon (P).

The development of a PAR-inspired (participative action research) project-based method, addressed to needs or problems identified by the local youth organisation Centro Social da Musgueiro, Lumiar, Lisbon, and achieved with relatively limited time and resources. The ‘action’ involved the making of a mural in a central public place. This project not only created a prominent public artwork that is owned and loved by the local community; it also enabled children and young people to consider and express their sense of place, to experience working together with others from different backgrounds, and to make a substantive difference to the place where they lived.status: Published onlin

Observeren, reproduceren, ageren: activatie vanuit ontwerp

I am trying to get a copy of the book. Once I will have it I will introduce the pages of the interview by Annette Kuhk with myself on the Alive Architecture projects. Furthermore I will add images of the pages of the article on my work.status: publishe

Adult polyglucosan body disease masquerading as "ALS with dementia of the Alzheimer type": An exceptional phenotype in a rare pathology

We describe an exceptional clinical picture, namely, cognitive impairment of the Alzheimer disease type in a man who later developed manifestations typical of amyotrophic lateral sclerosis and who was subsequently found to have adult polyglucosan body disease (APGBD) upon postmortem neuropathologic explorations. The combined occurrence of amyotrophic lateral sclerosis and cognitive impairment of the Alzheimer disease type in APGBD has not been reported before. This case also underlines the diverse clinical presentation of this rare clinicopathologic entity (namely APGBD) and highlights the importance of recognizing the unusual association of clinical features in making the diagnosis. Copyright © 2012 by Lippincott Williams & Wilkins.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Exploring Embodied Place Attachment Through Co‐Creative Art Trajectories: The Case of Mount Murals

The built and living environment in the Flemish region in Belgium is evolving noticeably. It is densifying at an ever‐faster pace and, along the way, becoming increasingly unfamiliar to its inhabitants. Many people face profound difficulties in autonomously and positively dealing with such drastic changes, causing their feeling of home to waver. Triggered by these challenges and supported by the local authority of a Flemish town, the experimental and co‐creative art project Mount Murals set out to stimulate new embodied interactions between and among local residents of various ages and backgrounds and with their built environment. These include remembering place‐related sentiments, being aware of body language that plays between participants while co‐creating and sensing an invigorating stimulus when seeing results. Awakening intrinsic appreciation in people for their own environment and associated social relationships stimulates an inclusive dealing with estranged relationships in space. Referring to the relational neuroscience principles attachment, co‐creating and co‐regulating as a modus of relational resonating, we explore how and under which conditions Mount Murals’ co‐creative art trajectory supports an evolving embodied place attachment, an essential element of the sense of belonging, in participants. By embedding assets inherent to art creation in action research and starting with meaningful everyday objects, Mount Murals carries forward an art expression that considers the co‐creation process and its co‐creative products as equally important

General Introduction – Spatial Quality Revisited.

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