47 research outputs found

    Collaborative Business Process Management - A Literature-based Analysis of Methods for Supporting Model Understandability

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    Due to the growing amount of cooperative business scenarios, collaborative Business Process Management (cBPM) has emerged. The increased number of stakeholders with minor expertise in process modeling leads to a high relevance of model understandability in cBPM contexts. Despite extensive works in the research fields of cBPM and model understandability in BPM, there is no analysis and comprehensive overview of methods supporting process model understandability in cBPM scenarios. To address this research gap, this paper presents the results of a literature review. The paper identifies concepts for supporting model understandability in BPM, provides an overview of methods implementing these concepts, and discusses the methods’ applicability in cBPM. The four concepts process model transformation, process model visualization, process model description, and modeling support are introduced. Subsequently, 69 methods are classified and discussed in the context of cBPM. Results contribute to revealing existing academic voids and can guide practitioners in cBPM scenarios

    Will They Die Another Day? A Decision Support Perspective on Reusing Electric Vehicle Batteries

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    The diffusion of electric mobility suffers from an immature and expensive battery technology. Reusing electric vehicle batteries (EVBs) is a prospective opportunity for lowering the total costs of ownership of electric vehicles and using scarce natural resources more efficiently. However, to determine how to reuse a battery is a complex decision problem. In this study we set out to develop a design theory for a class of decision support systems (DSSs) that implement two main functions: First, a consideration set of feasible reuse scenarios is compiled based on an assess-ment of a battery’s structure and condition. Second, an offering is configured based on bun-dling batteries with customized services. We conclude with an outlook to our ongoing design science project that will, amongst others, explore to what extent systems instantiated from the design theory can remedy adverse effects caused by the ‘lemon market’ properties of the sec-ond-hand battery market

    Using a Generic Model Query Approach to Allow for Process Model Compliance Checking – An Algorithmic Perspective

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    Increased regulation forces financial companies to assure their business processes’ compliance with legal and company-internal rules. In this paper, we introduce a model-driven business process compliance checking approach. It allows for defining compliance rules and identifying their occurrences in process models based on a graph theory-based approach. We outline the challenges to be met in the conceptualization of the approach and especially its implementation through suitable algorithms. Furthermore, we present an according modeling tool and evaluate the approach against related work

    Quantification of mixture composition, liquid-phase fraction and temperature in transcritical sprays

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    How do fuel and air mix, if a liquid fuel is injected into an environment featuring pressure and temperature that exceed the critical pressure and the critical temperature of the fuel? It is subject of current discussion on whether and if so when, the fuel/air-mixture becomes supercritical or not. We here report experimental data comprising three mixture properties that are relevant for the current debate, all spatially and temporally resolved throughout the spray and injection event: The overall composition of the fuel/air-mixture, the liquid fraction of the fuel/air-mixture, and the temperature of the liquid phase. To this end, we applied Raman spectroscopy and gave special attention to the signature of the Raman OH-band of ethanol, which we used as fuel. Its signature is connected to the development of a hydrogen bonded network between the ethanol molecules and thus extremely sensitive to thermodynamic state and temperature. Measurements were carried out in a high-pressure, high-temperature combustion vessel in a pressure range of 3−8 MPa and a temperature range of 573−923 K. For the highest set temperature we found ethanol in liquid-like mixtures that exceeded the mixture critical temperature. This is an indication of the existence of a single-phase mixing path

    Exact likelihood computation in Boolean networks with probabilistic time delays, and its application in signal network reconstruction

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    Motivation: For biological pathways, it is common to measure a gene expression time series after various knockdowns of genes that are putatively involved in the process of interest. These interventional time-resolved data are most suitable for the elucidation of dynamic causal relationships in signaling networks. Even with this kind of data it is still a major and largely unsolved challenge to infer the topology and interaction logic of the underlying regulatory network. Results: In this work, we present a novel model-based approach involving Boolean networks to reconstruct small to medium-sized regulatory networks. In particular, we solve the problem of exact likelihood computation in Boolean networks with probabilistic exponential time delays. Simulations demonstrate the high accuracy of our approach. We apply our method to data of Ivanova et al. (2006), where RNA interference knockdown experiments were used to build a network of the key regulatory genes governing mouse stem cell maintenance and differentiation. In contrast to previous analyses of that data set, our method can identify feedback loops and provides new insights into the interplay of some master regulators in embryonic stem cell development. Availability and implementation: The algorithm is implemented in the statistical language R. Code and documentation are available at Bioinformatics online. Contact: [email protected] or [email protected] Supplementary information: Supplementary Materials are available at Bioinfomatics onlin

    Koi-Herpesvirus Übertragung vom Laichkarpfen zur Brut?: Untersuchungen zur Risikobewertung der Übertragung des Koi-Herpesvirus durch LaichkarpfenbestĂ€nde zur Sicherung nachhaltiger Sanierungserfolge der KHV-I in Sachsen und im Hinblick auf die Erhaltung der genetischen Vielfalt der LaichfischbestĂ€nde in Sachsen

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    Im Bericht wird bisher ungeklĂ€rten Fragen des Übertragungswegs des Koi-Herpesvirus nachgegangen. In latent infizierten LaichkarpfenbestĂ€nden, in deren Geschlechtsprodukten und in befruchteten Eiern lĂ€sst sich das Virus (KHV) nachweisen. Eine Infektion der frisch geschlĂŒpften Karpfenbrut scheint allerdings nicht zu erfolgen. BrĂŒtlinge von Laichfischen, die aus KHV-positiven BestĂ€nden stammen, haben eine höhere Resistenz gegenĂŒber einer erneuten Infektion mit dem KHV. Der Beitrag richtet sich an praktische FischzĂŒchter, FachtierĂ€rzte, Fischereiwissenschaftler und an die interessierte Öffentlichkeit. Redaktionsschluss: 31.03.202

    Life as a fortress – structure, function, and adaptive values of morphological and chemical defense in the oribatid mite Euphthiracarus reticulatus (Actinotrichida)

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    Background: Oribatid mites are among the primordial decomposer faunal elements and potential prey organisms insoil. Among their myriad morphological defenses are strong sclerotization and mineralization, cuticular tecta, and the “ptychoid” body-form, which allows to attain an encapsulated, seed-like appearance. Most oribatid mites possess a pair of exocrine glands that produce blends of hydrocarbons, terpenes, aromatics, alkaloids and cyanogenic compounds.Many species evolved “holistic” defensive strategies by combining several morphological and chemical traits. Methods: We describe the morphological and chemical bases of defense in the ptychoid oribatid Euphthiracarus reticulatus. The functional morphology was investigated with synchrotron X-ray microtomography (SRÎŒCT) and highspeed life-radiography. Gland secretions were collected from 20,000 adult specimens, purified and fractionated by preparative capillary gas chromatography (pcGC) and analyzed by gas chromatography / mass spectrometry (GC/MS), high-resolution mass spectrometry (HRMS), and nuclear magnetic resonance spectroscopy (NMR). The adaptive values of morphological and chemical defenses were estimated in bioassays against three predators: a similar-sized gamasid mite (Stratiolaelaps miles, ca. 0.8 mm, with slender chelicera for piercing membranous cuticular regions), and two larger staphylinid beetles, Stenus juno (ca. 7 mm, bearing a harpoon-like sticky labium and sickle-shaped mandibles) and Othius punctulatus (ca. 14 mm, bearing plesiomorphic chewing mandibles). Results: The secretions comprised two components: the diterpene ÎČ-springene and a novel compound with a mass of 276 g/mol – eventually elucidated as 2-(but-1-en-1-yl)-4-butylidene-3-(pent-2-en-1-yl)-pentanedial, to which we assign the trivial name ÎŽ-acaridial. Upon attacks by S. juno, E. reticulatus reacted quickly: within 150 ms from the first contact the encapsulation was almost completed – less time than the beetle needed to retract the labium and transfer the mite to the mandibles. Chemically-defended specimens of E. reticulatus effectively repelled all predators. After depletion of oil-gland reservoirs, however, O. punctulatus easily fed on the mites while S. miles and S. juno were not able to overcome the morphological barrier of strong cuticle and ptychoid body form. Conclusion: Such an effective, holistic defense strategy, involving both morphological and chemical traits, probably carries high resource-costs, but it allows adult euphthiracaroid mites to occupy an almost “enemy-free space” despite the high diversity of predators in soil

    Life as a fortress structure, function, and adaptive values of morphological and chemical defense in the oribatid mite Euphthiracarus reticulatus (Actinotrichida)

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    Background Oribatid mites are among the primordial decomposer faunal elements and potential prey organisms in soil. Among their myriad morphological defenses are strong sclerotization and mineralization, cuticular tecta, and the “ptychoid” body-form, which allows to attain an encapsulated, seed-like appearance. Most oribatid mites possess a pair of exocrine glands that produce blends of hydrocarbons, terpenes, aromatics, alkaloids and cyanogenic compounds. Many species evolved “holistic” defensive strategies by combining several morphological and chemical traits. Methods We describe the morphological and chemical bases of defense in the ptychoid oribatid Euphthiracarus reticulatus. The functional morphology was investigated with synchrotron X-ray microtomography (SRCT) and high-speed life-radiography. Gland secretions were collected from 20,000 adult specimens, purified and fractionated by preparative capillary gas chromatography (pcGC) and analyzed by gas chromatography / mass spectrometry (GC/MS), high-resolution mass spectrometry (HRMS), and nuclear magnetic resonance spectroscopy (NMR). The adaptive values of morphological and chemical defenses were estimated in bioassays against three predators: a similar-sized gamasid mite (Stratiolaelaps miles, ca. 0.8 mm, with slender chelicera for piercing membranous cuticular regions), and two larger staphylinid beetles, Stenus juno (ca. 7 mm, bearing a harpoon-like sticky labium and sickle-shaped mandibles) and Othius punctulatus (ca. 14 mm, bearing plesiomorphic chewing mandibles). Results The secretions comprised two components: the diterpene -springene and a novel compound with a mass of 276 g/mol eventually elucidated as 2-(but-1-en-1-yl)-4-butylidene-3-(pent-2-en-1-yl)-pentanedial, to which we assign the trivial name -acaridial. Upon attacks by S. juno, E. reticulatus reacted quickly: within 150 ms from the first contact the encapsulation was almost completed less time than the beetle needed to retract the labium and transfer the mite to the mandibles. Chemically-defended specimens of E. reticulatus effectively repelled all predators. After depletion of oil-gland reservoirs, however, O. punctulatus easily fed on the mites while S. miles and S. juno were not able to overcome the morphological barrier of strong cuticle and ptychoid body form. Conclusion Such an effective, holistic defense strategy, involving both morphological and chemical traits, probably carries high resource-costs, but it allows adult euphthiracaroid mites to occupy an almost “enemy-free space” despite the high diversity of predators in soil.(VLID)286348

    Life as a fortress – structure, function, and adaptive values of morphological and chemical defense in the oribatid mite Euphthiracarus reticulatus (Actinotrichida)

    Get PDF
    Background: Oribatid mites are among the primordial decomposer faunal elements and potential prey organisms in soil. Among their myriad morphological defenses are strong sclerotization and mineralization, cuticular tecta, and the “ptychoid” body-form, which allows to attain an encapsulated, seed-like appearance. Most oribatid mites possess a pair of exocrine glands that produce blends of hydrocarbons, terpenes, aromatics, alkaloids and cyanogenic compounds. Many species evolved “holistic” defensive strategies by combining several morphological and chemical traits. Methods: We describe the morphological and chemical bases of defense in the ptychoid oribatid Euphthiracarus reticulatus. The functional morphology was investigated with synchrotron X-ray microtomography (SRÎŒCT) and high-speed life-radiography. Gland secretions were collected from 20,000 adult specimens, purified and fractionated by preparative capillary gas chromatography (pcGC) and analyzed by gas chromatography / mass spectrometry (GC/MS), high-resolution mass spectrometry (HRMS), and nuclear magnetic resonance spectroscopy (NMR). The adaptive values of morphological and chemical defenses were estimated in bioassays against three predators: a similar-sized gamasid mite (Stratiolaelaps miles, ca. 0.8 mm, with slender chelicera for piercing membranous cuticular regions), and two larger staphylinid beetles, Stenus juno (ca. 7 mm, bearing a harpoon-like sticky labium and sickle-shaped mandibles) and Othius punctulatus (ca. 14 mm, bearing plesiomorphic chewing mandibles). Results: The secretions comprised two components: the diterpene ÎČ-springene and a novel compound with a mass of 276 g/mol – eventually elucidated as 2-(but-1-en-1-yl)-4-butylidene-3-(pent-2-en-1-yl)-pentanedial, to which we assign the trivial name ÎŽ-acaridial. Upon attacks by S. juno, E. reticulatus reacted quickly: within 150 ms from the first contact the encapsulation was almost completed – less time than the beetle needed to retract the labium and transfer the mite to the mandibles. Chemically-defended specimens of E. reticulatus effectively repelled all predators. After depletion of oil-gland reservoirs, however, O. punctulatus easily fed on the mites while S. miles and S. juno were not able to overcome the morphological barrier of strong cuticle and ptychoid body form. Conclusion: Such an effective, holistic defense strategy, involving both morphological and chemical traits, probably carries high resource-costs, but it allows adult euphthiracaroid mites to occupy an almost “enemy-free space” despite the high diversity of predators in soil
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