Development of an international harmonization scheme for salt water fish toxicity tests

The proceeding deterioration of the marine environment demonstrates the need and the urgency to take appropriate measures. To obtain significant results all the practical efforts made so far must be sustained by national and international conventions and wherever necessary even by more strict regulations. One of the major objectives of the administrative and scientific authorities involved is to establish an harmonized scheme for toxicity testing on marine organisms under controlled laboratory conditions, in order to make a meaningful preliminary hazard assessment for the marine environment. In this respect, and to screen out those substances, which show an immediate adverse effect, a simple, cheap and convenient toxicity test on saltwater fish is urgently needed. The state of the art in this field is, however, not developed as far as it is for freshwater species, for which standards already exist: i.e. ISO, EPA, ASTM, OECD. This paper attempts to find out which simple methods are more or leas commonly used, and if there is a trend in the development of an international harmonized toxicity- testing procedure for saltwater fishes

An integrated study of earth resources in the state of California using remote sensing techniques

The University of California has been conducting an investigation which seeks to determine the usefulness of modern remote sensing techniques for studying various components of California's earth resources complex. Most of the work has concentrated on California's water resources, but with some attention being given to other earth resources as well and to the interplay between them and California's water resources

Atomic multipole relaxation rates near surfaces

The spontaneous relaxation rates for an atom in free space and close to an absorbing surface are calculated to various orders of the electromagnetic multipole expansion. The spontaneous decay rates for dipole, quadrupole and octupole transitions are calculated in terms of their respective primitive electric multipole moments and the magnetic relaxation rate is calculated for the dipole and quadrupole transitions in terms of their respective primitive magnetic multipole moments. The theory of electromagnetic field quantization in magnetoelectric materials is used to derive general expressions for the decay rates in terms of the dyadic Green function. We focus on the decay rates in free space and near an infinite half space. For the decay of atoms near to an absorbing dielectric surface we find a hierarchy of scaling laws depending on the atom-surface distance z.Comment: Updated to journal version. 16 page

A Review of the Toxicity and Phytochemistry of Medicinal Plant Species Used by Herbalists in Treating People Living With HIV/AIDS in Uganda

Introduction: Despite concerns about toxicity, potentially harmful effects and herb-drug interactions, the use of herbal medicines remains widely practiced by people living with HIV/AIDS (PLHIV) in Uganda. Objective: The objective of the paper was to comprehensively review the literature on the toxicity and chemical composition of commonly used medicinal plant species in treating PLHIV in Uganda. Methods: We reviewed relevant articles and books published over the last sixty years on ethnobotany, antiviral/anti-HIV activity, toxicity, phytochemistry of Vachellia hockii, Albizia coriaria, Bridelia micrantha, Cryptolepis sanguinolenta, Erythrina abyssinica, Gardenia ternifolia, Gymnosporia senegalensis, Psorospermum febrifugium, Securidaca longipendunculata, Warburgia ugandensis and Zanthoxylum chalybeum and their synonyms. We searched PubMed, Web of Science, Scopus, Science Direct and Google Scholar. Discussion: Most of the plant species reviewed apart from P. febrifugium, S. longipedunculata and C. sanguinolenta lacked detailed phytochemical analyses as well as the quantification and characterization of their constituents. Crude plant extracts were the most commonly used. However, purified/single component extracts from different plant parts were also used in some studies. The U87 human glioblastoma was the most commonly used cell line. Water, ethanol, methanol and DMSO were the commonest solvents used. In some instances, isolated purified compounds/extracts such as Cryptolepine and Psorospermin were used. Conclusion: Cytotoxicity varied with cell type, solvent and extract type used making it difficult for direct comparison of the plant species. Five of the eleven plant species namely, A. coriaria, C. sanguinolenta, G. ternifolia, P. febrifugium and Z. chalybeum had no cytotoxicity studies in animal models. For the remaining six plant species, the crude aqueous and ethanol extracts were mainly used in acute oral toxicity studies in mice. Herbalists reported only A. coriaria and W. ugandensis to cause toxic side effects in humans. However, selective cytotoxic plant extracts can potentially be beneficial as anticancer or anti-tumour drugs

When, where, and why should we look for vestibular dysfunction in people with diabetes mellitus?

The biochemistry of diabetes mellitus results in multi-system tissue compromise that reduces functional mobility and interferes with disease management. Sensory system compromise, such as peripheral neuropathy and retinopathy, are specific examples of tissue compromise detrimental to functional mobility. There is lack of clarity regarding if, when, and where parallel changes in the peripheral vestibular system, an additional essential sensory system for functional mobility, occur as a result of diabetes. Given the systemic nature of diabetes and the plasticity of the vestibular system, there is even less clarity regarding if potential vestibular system changes impact functional mobility in a meaningful fashion. This commentary will provide insight as to when we should employ diagnostic vestibular function tests in people with diabetes, where in the periphery we should look, and why testing may or may not matter. The commentary concludes with recommendations for future research and clinical care

Photon-Graviton Amplitudes from the Effective Action

We report on the status of an ongoing effort to calculate the complete one-loop low-energy effective actions in Einstein-Maxwell theory with a massive scalar or spinor loop, and to use them for obtaining the explicit form of the corresponding M-graviton/N-photon amplitudes. We present explicit results for the effective actions at the one-graviton four-photon level, and for the amplitudes at the one-graviton two-photon level. As expected on general grounds, these amplitudes relate in a simple way to the corresponding four-photon amplitudes. We also derive the gravitational Ward identity for the 1PI one-graviton -- N photon amplitude.Comment: 9 pages, 2 figures, talk given by C. Schubert at "Supersymmetries and Quantum Symmetries - SQS`2011", JINR Dubna, July 18 - 23, 2011 (to appear in the Proceedings

Comparative study of semiclassical approaches to quantum dynamics

Quantum states can be described equivalently by density matrices, Wigner functions or quantum tomograms. We analyze the accuracy and performance of three related semiclassical approaches to quantum dynamics, in particular with respect to their numerical implementation. As test cases, we consider the time evolution of Gaussian wave packets in different one-dimensional geometries, whereby tunneling, resonance and anharmonicity effects are taken into account. The results and methods are benchmarked against an exact quantum mechanical treatment of the system, which is based on a highly efficient Chebyshev expansion technique of the time evolution operator.Comment: 32 pages, 8 figures, corrected typos and added references; version as publishe

Oxidation and emission of methane in a monomictic lake (Rotsee, Switzerland)

The build-up of methane in the hypolimnion of the eutrophic Lake Rotsee (Lucerne, Switzerland) was monitored over a full year. Sources and sinks of methane in the water column were characterized by measuring concentrations and carbon isotopic composition. In fall, high methane concentrations (up to 1mM) were measured in the anoxic water layer. In the oxic layer, methane concentrations were much lower and the isotopic composition shifted towards heavy carbon isotopes. Methane oxidation rates peaked at the interface between oxic and anoxic water layers at around 8-10m depth. The electron balance between the oxidants oxygen, sulphate, and nitrate, and the reductants methane, sulphide and ammonium, matched very well in the chemocline during the stratified season. The profile of carbon isotopic composition of methane showed strong indications for methane oxidation at the chemocline (including the oxycline). Aerobic methane oxidizing bacteria were detected at the interface using fluorescence in situ hybridization. Sequencing the responsible organisms from DGGE bands revealed that aerobic methanotrophs type I closely related to Methylomonas were present. Sulphate consumption occurred at the sediment surface and, only towards the end of the stagnation period, matched with a zone of methane consumption. In any case, the flux of sulphate below the chemocline was not sufficient to oxidize all the methane and other oxidants like nitrate, iron or manganese are necessary for the observed methane oxidation. Although most of the methane was oxidized either aerobically or anaerobically, Lake Rotsee was still a source of methane to the atmosphere with emission rates between 0.2mgCH4m−2day−1 in February and 7mgCH4m−2day−1 in Novembe