3,774 research outputs found

    Geoscience of Climate and Energy 12. Water Quality Issues in the Oil Sands Region of the Lower Athabasca River, Alberta

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    I summarize the controversies about industrial pollutants in freshwaters near the oil sands industrial area of Alberta, the inadequacies in environmental monitoring that have led to widespread misconceptions, and recent attempts to correct the problems.  Adequate data are available to show that mercury, other trace metals, and polycyclic aromatic compounds are being added by industry to the Athabasca river system and its watershed, although the relative contributions of industrial development and natural sources remain in question.  Recent improvements in water monitoring by Environment Canada show promise of resolving the controversies, although independent governance for Canada’s and Alberta’s water monitoring programs in the lower Athabasca River will be necessary to rebuild public confidence in the data and their interpretation by government and industry.  I document one success story in the Athabasca River: the elimination of dioxins from pulp mills in the mid-1990s has caused a consumption advisory for fish in the river to be repealed.SOMMAIREJe prĂ©sente ci-dessous un rĂ©sumĂ© des controverses concernant les polluants industriels dans les eaux douces Ă  proximitĂ© de la zone industrielle des sables bitumineux de l'Alberta, des lacunes dans la surveillance des milieux de vie Ă  l’origine d’idĂ©es fausses rĂ©pandues, et de rĂ©centes tentatives visant Ă  corriger les problĂšmes.  Des donnĂ©es adĂ©quates dĂ©montrent que l’industrie ajoute du mercure et d'autres mĂ©taux traces ainsi que des composĂ©s aromatiques polycycliques dans le systĂšme fluvial de la riviĂšre Athabasca et dans son bassin versant, bien que les contributions relatives provenant de ces activitĂ©s industrielles et de sources naturelles demeurent toujours en litige.  De rĂ©centes amĂ©liorations apportĂ©es au contrĂŽle des eaux par Environnement Canada permettent d’espĂ©rer une rĂ©solution des controverses, mais l’application d’une gouvernance indĂ©pendante des programmes de contrĂŽle de l'eau de l'Alberta du Canada dans la partie infĂ©rieure du fleuve Athabasca sera nĂ©cessaire pour rĂ©tablir la confiance de la population Ă  l’égard des donnĂ©es prĂ©sentĂ©es et de leur interprĂ©tation par le gouvernement et l'industrie.  Je dĂ©crie l’histoire d’une intervention rĂ©ussie dans la riviĂšre Athabasca, soit l'Ă©limination de dioxines provenant des usines de pĂąte du milieu des annĂ©es 1990 et qui a abouti Ă  l’abrogation d’un avis de limitation de la consommation de poisson dans la riviĂšre.DOI: http://dx.doi.org/10.12789/geocanj.2013.40.01

    Determining effects of an all weather logging road on winter woodland caribou habitat use in south-eastern Manitoba

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    The Owl Lake boreal woodland caribou population is the most southerly population in Manitoba. It is provincially ranked as a High Conservation Concern Population. Forestry operations exist in the area and there are plans for further forest harvest and renewal. The Happy Lake logging road is the only main access through the Owl Lake winter range. This logging road is currently closed to the public and access is limited to forestry operations during specific times of the year. An integrated forestry/caribou management strategy for the area provides for the maintenance of minimum areas of functional habitat. Habitat quality along the road was compared to habitat quality in the winter core use areas, within the winter range and outside the winter range. To evaluate the extent of functional habitat near the road, we conducted animal location and movement analysis using GPS data collected from January 2002 to March 2006. Habitat quality in the winter range, core use areas and along the road were assessed and found to be similar. Analysis of caribou locations and movement illustrate less use of high quality habitat adjacent to the Happy Lake Road. Loss of functional habitat is suggested to occur within 1 kilometre of the road. This potential loss of functional habitat should be incorporated into integrated forestry and caribou conservation strategies. Road management is recommended to minimize the potential sensory disturbance and associated impacts of all weather access on boreal woodland caribou

    Dicer regulates activation of the NLRP3 inflammasome

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    Inflammation plays a critical role in initiation of adaptive immunity, pathogen clearance and tissue repair. Interleukin (IL)-1ÎČ is a potent pro-inflammatory cytokine and therefore its production is tightly regulated: its secretion requires the assembly of a macromolecular protein complex, termed the inflammasome. Aberrant activation of the inflammasome has been linked to debilitating human diseases including chronic inflammatory and autoimmune diseases. Thus, there is a great interest in understanding how inflammasomes are regulated. Here we show that Dicer, an enzyme necessary for the production of mature micro-RNAs (miRNAs), is required for optimal activation of NLRP3 inflammasomes in bone marrow macrophages. Our data indicate that miRNAs may play an important role in promoting inflammasome activation

    Hydrodynamic simulations of merging clusters of galaxies

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    We present the results of high-resolution AP3M+SPH simulations of merging clusters of galaxies. We find that the compression and shocking of the core gas during a merger can lead to large increases in bolometric X-ray luminosities and emission-weighted temperatures of clusters. Cooling flows are completely disrupted during equal-mass mergers, with the mass deposition rate dropping to zero as the cores of the clusters collide. The large increase in the cooling time of the core gas strongly suggests that cooling flows will not recover from such a merger within a Hubble time. Mergers with subclumps having one eighth of the mass of the main cluster are also found to disrupt a cooling flow if the merger is head-on. However, in this case the entropy injected into the core gas is rapidly radiated away and the cooling flow restarts within a few Gyr of the merger. Mergers in which the subcluster has an impact parameter of 500 kpc do not disrupt the cooling flow, although the mass deposition rate is reduced by ∌30 per cent. Finally, we find that equal mass, off-centre mergers can effectively mix gas in the cores of clusters, while head on mergers lead to very little mixing. Gas stripped from the outer layers of subclumps results in parts of the outer layers of the main cluster being well mixed, although they have little effect on the gas in the core of the cluster. None of the mergers examined here resulted in the intracluster medium being well mixed globally

    Chandra Observation of Abell 2142: Survival of Dense Subcluster Cores in a Merger

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    We use Chandra data to map the gas temperature in the central region of the merging cluster A2142. The cluster is markedly nonisothermal; it appears that the central cooling flow has been disturbed but not destroyed by a merger. The X-ray image exhibits two sharp, bow-shaped, shock-like surface brightness edges or gas density discontinuities. However, temperature and pressure profiles across these edges indicate that these are not shock fronts. The pressure is reasonably continuous across these edges, while the entropy jumps in the opposite sense to that in a shock (i.e. the denser side of the edge has lower temperature, and hence lower entropy). Most plausibly, these edges delineate the dense subcluster cores that have survived a merger and ram pressure stripping by the surrounding shock-heated gas.Comment: Latex, 9 pages, 5 figures (including color), uses emulateapj.sty. Submitted to Ap

    Modification of pharmacokinetic and abuse-related effects of cocaine by human-derived cocaine hydrolase in monkeys

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    Although substantial research effort has focused on developing pharmacological treatments for cocaine abuse, no effective medications have been developed. Recent studies show that enzymes that metabolize cocaine in the periphery, forestalling its entry into the brain, can prevent cocaine toxicity and its behavioral effects in rodents. Here we report on effects of one such enzyme (Albu- CocH) on the pharmacokinetic and behavioral effects of cocaine in squirrel monkeys. Albu-CocH was developed from successive mutations of human butyrylcholinesterase (BChE) and has 1000- fold greater catalytic activity against cocaine than naturally occurring BChE. Pharmacokinetic studies showed that Albu-CocH (5 mg/kg) had a half-life of 56.6 hours in squirrel monkeys. In these studies, plasma levels of cocaine following i.v. 1 mg/kg cocaine were reduced two hours after administration of Albu-CocH, whereas plasma levels of the cocaine metabolite ecgonine methyl ester were increased. These effects were still evident 72 hrs following Albu-CocH administration. In behavioral experiments in monkeys, pretreatment with 5 mg/kg Albu-CocH dramatically decreased self-administration of a reinforcing dose of i.v. cocaine (30 ÎŒg/kg/ injection) for over 24 hours. Pretreatment with 5 mg/kg Albu-CocH also attenuated the reinstatement of extinguished cocaine self-administration by an i.v. priming injection of cocaine (0.1 or 0.3 mg/kg) and, in separate studies, attenuated the discriminative stimulus effects of cocaine. The ability of Albu-CocH to attenuate the abuse-related effects of cocaine in squirrel monkeys indicates that further investigation of BChE mutants as potential treatment for cocaine abuse and toxicity is warranted.This research was supported in part by the Intramural Research Program of the NIH, National Institute on Drug Abuse

    Alternative Fuel for Portland Cement Processing

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    The production of cement involves a combination of numerous raw materials, strictly monitored system processes, and temperatures on the order of 1500 °C. Immense quantities of fuel are required for the production of cement. Traditionally, energy from fossil fuels was solely relied upon for the production of cement. The overarching project objective is to evaluate the use of alternative fuels to lessen the dependence on non-renewable resources to produce portland cement. The key objective of using alternative fuels is to continue to produce high-quality cement while decreasing the use of non-renewable fuels and minimizing the impact on the environment. Burn characteristics and thermodynamic parameters were evaluated with a laboratory burn simulator under conditions that mimic those in the preheater where the fuels are brought into a cement plant. A drop-tube furnace and visualization method were developed that show potential for evaluating time- and space-resolved temperature distributions for fuel solid particles and liquid droplets undergoing combustion in various combustion atmospheres. Downdraft gasification has been explored as a means to extract chemical energy from poultry litter while limiting the throughput of potentially deleterious components with regards to use in firing a cement kiln. Results have shown that the clinkering is temperature independent, at least within the controllable temperature range. Limestone also had only a slight effect on the fusion when used to coat the pellets. However, limestone addition did display some promise in regards to chlorine capture, as ash analyses showed chlorine concentrations of more than four times greater in the limestone infused ash as compared to raw poultry litter. A reliable and convenient sampling procedure was developed to estimate the combustion quality of broiler litter that is the best compromise between convenience and reliability by means of statistical analysis. Multi-day trial burns were conducted at a full-scale cement plant with alternative fuels to examine their compatibility with the cement production process. Construction and demolition waste, woodchips, and soybean seeds were used as alternative fuels at a full-scale cement production facility. These fuels were co-fired with coal and waste plastics. The alternative fuels used in this trial accounted for 5 to 16 % of the total energy consumed during these burns. The overall performance of the portland cement produced during the various trial burns performed for practical purposes very similar to the cement produced during the control burn. The cement plant was successful in implementing alternative fuels to produce a consistent, high-quality product that increased cement performance while reducing the environmental footprint of the plant. The utilization of construction and demolition waste, woodchips and soybean seeds proved to be viable replacements for traditional fuels. The future use of these fuels depends on local availability, associated costs, and compatibility with a facilityñs production process
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