Neuroinfection survey at a neurological ward in a Brazilian tertiary teaching hospital

OBJECTIVES: This study was undertaken to characterize the neuroinfection profile in a tertiary neurological ward. INTRODUCTION: Neuroinfection is a worldwide concern and bacterial meningitis, tetanus and cerebral malaria have been reported as the commonest causes in developing countries. METHODS: From 1999 to 2007, all patients admitted to the Neurology Ward of Hospital das Clínicas, São Paulo University School of Medicine because of neuroinfection had their medical records reviewed. Age, gender, immunological status, neurological syndrome at presentation, infectious agent and clinical outcome were recorded. RESULTS: Three hundred and seventy four cases of neuroinfectious diseases accounted for 4.2% of ward admissions and the identification of infectious agent was successful in 81% of cases. Mean age was 40.5 + 13.4 years, 63.8% were male, 19.7% were immunocompromised patients and meningoencephalitis was the most common clinical presentation despite infectious agent. Viruses and bacteria were equally responsible for 29.4% of neuroinfectious diseases; parasitic, fungal and prion infections accounted for 28%, 9.6% and 3.5% respectively. Human immunodeficiency virus (HIV), herpes simplex virus 1 (HSV1), Mycobacterium tuberculosis, Treponema pallidum, Taenia solium, Schistosoma mansoni, Cryptococcus neoformans and Histoplasma capsulatum were the more common infectious pathogens in the patients. Infection mortality rate was 14.2%, of which 62.3% occurred in immunocompetent patients. CONCLUSION: Our institution appeared to share some results with developed and developing countries. Comparison with literature may be considered as quality control to health assistance

Vocal development in a large‐scale crosslinguistic corpus

This study evaluates whether early vocalizations develop in similar ways in children across diverse cultural contexts. We analyze data from daylong audio recordings of 49 children (1–36 months) from five different language/cultural backgrounds. Citizen scientists annotated these recordings to determine if child vocalizations contained canonical transitions or not (e.g., “ba” vs. “ee”). Results revealed that the proportion of clips reported to contain canonical transitions increased with age. Furthermore, this proportion exceeded 0.15 by around 7 months, replicating and extending previous findings on canonical vocalization development but using data from the natural environments of a culturally and linguistically diverse sample. This work explores how crowdsourcing can be used to annotate corpora, helping establish developmental milestones relevant to multiple languages and cultures. Lower inter‐annotator reliability on the crowdsourcing platform, relative to more traditional in‐lab expert annotators, means that a larger number of unique annotators and/or annotations are required, and that crowdsourcing may not be a suitable method for more fine‐grained annotation decisions. Audio clips used for this project are compiled into a large‐scale infant vocalization corpus that is available for other researchers to use in future work

Elective affinities of the Protestant ethic : Weber and the chemistry of capitalism

Peer reviewedPostprin

Beyond power:unbridging Foucault and Weber

Today, very few would doubt that there are plenty of reasons to liken Weber’s and Foucault’s theories of power. Nevertheless, their respective works have divergent ethical and ontological preoccupations which should be reconsidered. This paper explores Foucault’s account of a historical episode in Discipline and Punish and Weber’s theory of life spheres, uncovering evidence that there is a need to reassess the conceptual bridges which have been built so far. The exploration reveals a radical difference between a monological theory of power (Foucault) and a multidimensional approach to power (Weber). Yet by unbridging the two thinkers and focusing on other aspects of their theories along with their ideas about power, we also find that alternative links between the two frameworks may offer a more promising critical theory

Weber and Simmel’s philosophical and political stances : a dialogue in three acts

This article is an imagined dialogue between Weber and Simmel which makes a modest use of some of the resources of theatrical play in order to provide an overall portrait of both thinkers and to bring their thought to bear on our present. The dialogue consists of three acts focused on three central problematics in as many critical moments in Weber and Simmel’s lives: Act I takes place during the preparations for the first conference of the German Sociological Association and thus deals with the constitution of sociology as a socio-cultural science. Act II takes place amidst the First World War and its theme is evidently politics. Finally, Act III, where our two characters correspond instead of maintaining a face-to-face dialogue, is situated towards the end of the war and focuses on the attitude to life and indeed to death, as Simmel’s tragic yet admirable death takes place then. A brief introduction explains how we tried to use the possibilities of the dialogical form to expound Weber’s and Simmel’s thought, to compel them to confront their own blind spots and ‘unthoughts’, as well as to explore new ways of teaching the classics and transmitting their thought

Seasonality, intensity, and duration of rainfall extremes change in a warmer climate

Precipitation extremes are expected to intensify under climate change with consequent impacts in flooding and ecosystem functioning. Here we use station data and high‐resolution simulations from the WRF convection permitting climate model (∼4 km, 1 h) over the US to assess future changes in hourly precipitation extremes. It is demonstrated that hourly precipitation extremes and storm depths are expected to intensify under climate change and what is now a 20‐year rainfall will become a 7‐year rainfall on average for ∼ 75% of gridpoints over the US. This intensification is mostly expressed as an increase in rainfall tail heaviness. Statistically significant changes in the seasonality and duration of rainfall extremes are also exhibited over ∼ 95% of the domain. Our results suggest more non‐linear future precipitation extremes with shorter spell duration that are distributed more uniformly throughout the year

Substâncias húmicas da matéria orgânica do solo em cultivo de café com enriquecimento atmosférico de CO2.

Os possíveis efeitos da mudança climática devido ao aumento da concentração de CO2 atmosférico podem alterar as aptidões agrícolas nas áreas de regiões tropicais, podendo haver redução na produtividade de determinadas culturas (Solomom et al., 2007). Pesquisa agronômica tendem a investigar o efeito aumento da concentração do CO2 para plantas, pois o CO2 constitui um substrato primário para a fotossíntese e sua elevação pode estimular a produção de biomassa pela planta, consequentemente aumentar teores de carbono orgânico do solo, o que contribui para o aumento da matéria orgânica (Hungate et al., 2009). Entretanto, a dinâmica da matéria orgânica e dos nutrientes em solo cultivado sob elevada concentração de CO2 ainda é pouco estudada e compreendida, principalmente no Brasil. Os estudos envolvendo o enriquecimento atmosférico com CO2 são relativamente novos e permitem uma ampla investigação sobre o tema. Conduzidos em diferentes países em com as mais diversas plantas, os experimentos do tipo FACE (Free-Air Carbon Dioxide Enrichment) têm se mostrado uma importante fonte de conhecimento para antecipar possíveis problemas nos sistemas ecológicos e de produção agrícola (Lenhart et al., 2016). O objetivo deste trabalho foi verificar os possíveis efeitos de enriquecimento atmosférico de CO2 através do experimento FACE com os teores de C nas substâncias húmicas da matéria orgânica do solo (MOS) nas camadas superficiais e também uma quantificação do grau de humificação da MOS