39 research outputs found

    Artisanal fisheries in the Solomon Islands: The Wantok paradigm in West Guadalcanal

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    Technical report of the 2018-2020 JSPS KAKENHI project 18H03427Research Category: Grant-in-Aid for Scientific Research (B)、Principal Investigator: Shoichi Kiyama (Kyoto University)Foreword [i]Acknowledgements [iv]1. Introduction [1]2. Data Collection [26]3. Socio-economic and Demographic Characteristics [38]4. Wantokism [45]5. Fishing Activities and Networks [53]6. Cooperative Behaviour and Conflict Resolution [82]7. Discussion and Future Tasks [105]Appendix A: Social Network Analysis [114]Appendix B: The Questionnaire [119]References [139

    Synthesis and Luminescence Properties of Near-Infrared N-Heterocyclic Luciferin Analogues for In Vivo Optical Imaging

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    As a means of achieving highly sensitive bioluminescence imaging of deep tissues utilizing the firefly luciferin-luciferase (L-L) reaction, we previously reported a luciferin analogue, AkaLumine, which exhibits high cell-permeability and emits near-infrared (NIR) light with high tissue-penetration by the L-L reaction. However, while AkaLumine enables us to observe targets in deep tissues, its poor solubility in aqueous media limits its utility for in vivo imaging. Herein, to address this issue, we have synthesized three AkaLumine derivatives with N-heterocyclic aromatic rings as new red luciferin analogues that have substantially higher solubility than that of AkaLumine in phosphate buffered saline solution. One of the derivatives (herein termed seMpai) exhibits an emission maximum at 675 nm upon L-L reaction with Photinus pyralis luciferase and presents an activity in mouse-tissue imaging similar to that of AkaLumine. It is hoped that seMpai will extend the application of high-sensitivity NIR bioluminescence imaging in a wide range of biomedical research fields

    Measurement of Danazol and its metabolites by automated direct assay system

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    An automated direct assay system using high performance liquid chromatography was developed for teh measurement of Danazol ; DA and its two metabolites, △(1)-2-hydroxymethylethisterone (△(1)-2-HME), and 2-hydroxymethylethisterone (2-HME), in biologi-cal fluid (human serum and ascites). Serum concentrations of these compounds were measured up to 24 h following a single oral administration of 200mg of DA to 6 females with en-dometriosis. The maximum serum concentration of DA, △(1)-2-HME and 2-HME was 208, 44 and 58ng/ml, respectively. The serum half-life of DA, △(1)-2-HME and 2-HME was 7.9, 4.3 and 4.4 h, respectively. The mean serum concentration of DA and its two metabolites at the the sampling time (2 h after oral administration of 200mg of DA every 4 weeks) hardly changed in the patients administered 400mg/day of DA over a period of 16 weeks. DA and △(1)-2-HME were detectable in ascites 2, 4 and 8 h after oral administration of 200mg of DA, and 2-HME was detectable in ascites at 4 and 8 h. This system could quantify DA and its matabolites easily and simultaneously, and was considered to be valuable in the studies on the relationship between the pharmaco-kinetics and the clinical effects of DA

    The impact of stock collapse on small-scale fishers’ behavior: Evidence from Japan

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    To implement effective resource management and development policies, understanding behavioral responses of resource users to environmental changes and incentives created by management systems is imperative. A small-scale mixed fishery in the Maizuru Bay, Japan provides a natural experiment to evaluate changes in small-scale fishersâ harvesting and targeting behavior over the years that one of the key species in the fishery experienced a collapse of the stock. Using data on individual fishers across the pre- and post-collapse periods, we find that inefficient fishers were forced to shut down or stay idle along with the collapse of the stock, and this behavior led to an increase in the overall efficiency in the production of clams. The depletion of the stock, however, imposed a natural constraint on the operation, resulting in a significant decline in the maximum production achievable by the remaining fishers. We further show that the collapse of the stock not only affected the harvesting behavior against the declining species but also led to the expansion of the fishing capacity and effort to catch other species and the development of aquaculture as an alternative form of fish production in the region.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author

    A Case of Gastric Plasmacytoma Presenting Severe Anemia

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    Mechanical Properties of Abandoned and Closed Roadways in the Kushiro Coal Mine, Japan

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    The objective of this research is to clarify the mechanical properties and self-healing ability of Excavation Damaged Zone (EDZ) around rock caverns in clastic rock. Observations of nearly 100 closed roadways up to 50 years old, which can be regarded as very severe EDZs with no initial sealability and are up to 300 m deep in clastic rock, were made at Kushiro Coal Mine, Japan, to accomplish the objective. Most old roadways were closed, though a few remain open. Closure of old roadways was mainly due to roof deflection and/or floor heave. Large plastic deformations dominated; however, severe fractures were seldom observed in closed old roadways. Rayleigh wave velocity and hydraulic conductivity in the closed old roadways were in the range of 0.3 - 1.2 km/s and 5 x 10^[-7] - 1 x 10^[-7]m/s, respectively, and those in EDZ and EdZ (Excavation disturbed Zone) around recently excavated roadways were 1.1 - 1.8 km/s and 1 x 10^[-8] - 5 x 10^[-8] m/s, respectively. The extent of EDZ around the present tailgate was in the range of 1 m to 5 m. Mechanical excavation and prevention from water are suggested as the key points for long-term maintenance of rock repositories. Pressurization from inside the cavern to decrease the permeability of EDZ is proposed for maintenance of rock repositories in medium-hard clastic rock masses at similar depths for long periods
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