The influence of binarity on the morpho-kinematics of planetary nebulae

The role of central star binarity in the shaping of planetary nebulae (PNe) has been the subject of much debate, with single stars believed to be incapable of producing the most highly collimated morphologies. However, observational support for binary-induced shaping has been sadly lacking. Here, we highlight the results of a continuing programme to spatio-kinematically model the morphologies of all PNe known to contain a close binary central star. Spatio-kinematical modelling is imperative for these objects, as it circumvents the degeneracy between morphology and orientation which can adversely affect determinations of morphology based on imaging alone. Furthermore, spatio-kinematical modelling accurately determines the orientation of the nebular shell, allowing the theoretically predicted perpendicular alignment, between nebular symmetry axis and binary orbital plane, to be tested. To date, every PN subjected to this investigation has displayed the predicted alignment, indicating that binarity has played an important role in the formation and evolution of these nebulae. The further results from this programme will be key, not only in determining whether binary interaction is responsible for shaping the studied PNe, but also in assessing the importance of binarity in the formation and evolution of all PNe in general.Comment: 2 pages, 2 tables, proceedings of the IAU Symposium No. 283, Planetary Nebulae: An Eye to the Futur

Efecto de la temperatura en las propiedades reológicas de la pulpa de melón (Cucumis melo)

El melón (Cucumis melo) es un fruto de alto consumo a nivel nacional, lo que le otorga una gran importancia a  su cultivo, permitiendo exportación y transformación de la materia prima, por lo cual es necesario el estudio de sus propiedades reológicas con el fin de lograr optimizar los diferentes métodos de procesamiento. El objetivo principal de esta investigación es establecer la influencia de la temperatura sobre el comportamiento reológico de la pulpa de melón, por lo cual se efectuaron curvas de flujo viscoso en estado estacionario en un rango de temperaturas que van desde los 10°C hasta los 60°C. La evaluacion de las propiedades reológicas de la pulpa se analizaron de acuerdo a la variacion de la temperatura. Las pruebas se llevaron a cabo mediante un Sistema de Reómetro Avanzado Modular Haake Mars 60. La pulpa de melón tuvo un comportamiento no Newtoniano del, tipo pseudoplástico o reofluidificante (shear thining) en todos los casos, la relación entre la viscosidad y la velocidad de deformación se ajustó al modelo de Carreau-Yasuda (R2> 0,97.). El ajuste de la ecuación de Arrhenius con los datos arrojados de la viscosidad aparente de la pulpa fue adecuado con un R2>0,92. Estos resultados describen el comportamiento de la pulpa de melón, permitiendo su uso para futuros trabajos y aplicaciones en el desarrollo de procesos de transformación de las pulpas de melón como materia prima

The Astropy Problem

The Astropy Project (http://astropy.org) is, in its own words, "a community effort to develop a single core package for Astronomy in Python and foster interoperability between Python astronomy packages." For five years this project has been managed, written, and operated as a grassroots, self-organized, almost entirely volunteer effort while the software is used by the majority of the astronomical community. Despite this, the project has always been and remains to this day effectively unfunded. Further, contributors receive little or no formal recognition for creating and supporting what is now critical software. This paper explores the problem in detail, outlines possible solutions to correct this, and presents a few suggestions on how to address the sustainability of general purpose astronomical software

Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial

Background: Short-term treatment for people with type 2 diabetes using a low dose of the selective endothelin A receptor antagonist atrasentan reduces albuminuria without causing significant sodium retention. We report the long-term effects of treatment with atrasentan on major renal outcomes. Methods: We did this double-blind, randomised, placebo-controlled trial at 689 sites in 41 countries. We enrolled adults aged 18–85 years with type 2 diabetes, estimated glomerular filtration rate (eGFR)25–75 mL/min per 1·73 m 2 of body surface area, and a urine albumin-to-creatinine ratio (UACR)of 300–5000 mg/g who had received maximum labelled or tolerated renin–angiotensin system inhibition for at least 4 weeks. Participants were given atrasentan 0·75 mg orally daily during an enrichment period before random group assignment. Those with a UACR decrease of at least 30% with no substantial fluid retention during the enrichment period (responders)were included in the double-blind treatment period. Responders were randomly assigned to receive either atrasentan 0·75 mg orally daily or placebo. All patients and investigators were masked to treatment assignment. The primary endpoint was a composite of doubling of serum creatinine (sustained for ≥30 days)or end-stage kidney disease (eGFR <15 mL/min per 1·73 m 2 sustained for ≥90 days, chronic dialysis for ≥90 days, kidney transplantation, or death from kidney failure)in the intention-to-treat population of all responders. Safety was assessed in all patients who received at least one dose of their assigned study treatment. The study is registered with ClinicalTrials.gov, number NCT01858532. Findings: Between May 17, 2013, and July 13, 2017, 11 087 patients were screened; 5117 entered the enrichment period, and 4711 completed the enrichment period. Of these, 2648 patients were responders and were randomly assigned to the atrasentan group (n=1325)or placebo group (n=1323). Median follow-up was 2·2 years (IQR 1·4–2·9). 79 (6·0%)of 1325 patients in the atrasentan group and 105 (7·9%)of 1323 in the placebo group had a primary composite renal endpoint event (hazard ratio [HR]0·65 [95% CI 0·49–0·88]; p=0·0047). Fluid retention and anaemia adverse events, which have been previously attributed to endothelin receptor antagonists, were more frequent in the atrasentan group than in the placebo group. Hospital admission for heart failure occurred in 47 (3·5%)of 1325 patients in the atrasentan group and 34 (2·6%)of 1323 patients in the placebo group (HR 1·33 [95% CI 0·85–2·07]; p=0·208). 58 (4·4%)patients in the atrasentan group and 52 (3·9%)in the placebo group died (HR 1·09 [95% CI 0·75–1·59]; p=0·65). Interpretation: Atrasentan reduced the risk of renal events in patients with diabetes and chronic kidney disease who were selected to optimise efficacy and safety. These data support a potential role for selective endothelin receptor antagonists in protecting renal function in patients with type 2 diabetes at high risk of developing end-stage kidney disease. Funding: AbbVie

Resolving the circumstellar environment of the galactic B[e] supergiant atar MWC 137 from large to small scales

The Galactic object MWC 137 has been suggested to belong to the group of B[e] supergiants. However, with its large-scale optical bipolar ring nebula and high-velocity jet and knots, it is a rather atypical representative of this class. We performed multiwavelength observations spreading from the optical to the radio regimes. Based on optical imaging and long-slit spectroscopic data, we found that the northern parts of the large-scale nebula are predominantly blueshifted, while the southern regions appear mostly redshifted. We developed a geometrical model consisting of two double cones. Although various observational features can be approximated with such a scenario, the observed velocity pattern is more complex. Using near-infrared integral-field unit spectroscopy, we studied the hot molecular gas in the vicinity of the star. The emission from the hot CO gas arises in a small-scale disk revolving around the star on Keplerian orbits. Although the disk itself cannot be spatially resolved, its emission is reflected by the dust arranged in arc-like structures and the clumps surrounding MWC 137 on small scales. In the radio regime, we mapped the cold molecular gas in the outskirts of the optical nebula. We found that large amounts of cool molecular gas and warm dust embrace the optical nebula in the east, south, and west. No cold gas or dust was detected in the north and northwestern regions. Despite the new insights into the nebula kinematics gained from our studies, the real formation scenario of the large-scale nebula remains an open issue.Fil: Kraus, Michaela. Astronomický Ústav, Akademie Véd Ceské Republiky;Fil: Liimets, Tiina. Tarty Observatory, Tartumaa, Estonia;Fil: Cappa, Cristina Elisabeth. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Argentino de Radioastronomía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Argentino de Radioastronomía; ArgentinaFil: Cidale, Lydia Sonia. Universidad Nacional de la Plata. Facultad de Ciencias Astronómicas y Geofísicas; ArgentinaFil: Nickeler , Dieter H.. Astronomický Ústav, Akademie Véd Ceské Republiky;Fil: Duronea, Nicolas Urbano. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Argentino de Radioastronomía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Argentino de Radioastronomía; ArgentinaFil: Arias, Maria L.. Universidad Nacional de la Plata. Facultad de Ciencias Astronómicas y Geofísicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Astrofísica La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas. Instituto de Astrofísica la Plata; ArgentinaFil: Gunawan, Diah S.. Universidad de Valparaíso; ChileFil: Oksala, Mary E.. California Lutheran University; Estados UnidosFil: Borges Fernandes, Marcelo. Ministério de Ciencia, Tecnologia e Innovacao. Observatorio Nacional; Brasi

Report of the Topical Group on Cosmic Probes of Fundamental Physics for Snowmass 2021

Cosmic Probes of Fundamental Physics take two primary forms: Very high energy particles (cosmic rays, neutrinos, and gamma rays) and gravitational waves. Already today, these probes give access to fundamental physics not available by any other means, helping elucidate the underlying theory that completes the Standard Model. The last decade has witnessed a revolution of exciting discoveries such as the detection of high-energy neutrinos and gravitational waves. The scope for major developments in the next decades is dramatic, as we detail in this report

Report of the Topical Group on Cosmic Probes of Fundamental Physics for for Snowmass 2021

International audienceCosmic Probes of Fundamental Physics take two primary forms: Very high energy particles (cosmic rays, neutrinos, and gamma rays) and gravitational waves. Already today, these probes give access to fundamental physics not available by any other means, helping elucidate the underlying theory that completes the Standard Model. The last decade has witnessed a revolution of exciting discoveries such as the detection of high-energy neutrinos and gravitational waves. The scope for major developments in the next decades is dramatic, as we detail in this report

Report of the Topical Group on Cosmic Probes of Fundamental Physics for for Snowmass 2021

International audienceCosmic Probes of Fundamental Physics take two primary forms: Very high energy particles (cosmic rays, neutrinos, and gamma rays) and gravitational waves. Already today, these probes give access to fundamental physics not available by any other means, helping elucidate the underlying theory that completes the Standard Model. The last decade has witnessed a revolution of exciting discoveries such as the detection of high-energy neutrinos and gravitational waves. The scope for major developments in the next decades is dramatic, as we detail in this report