1,579 research outputs found
Movimientos sociales ¿realidad o ficción?
Al revisar los antecedentes y los escenariosactuales de los movimientos sociales en Colombiay el mundo, parece -alentador factor común en el desarrollo desus actividades, y es la falta de resultados detransformación social reales, concretos y permanentesen el tiempo. El movimiento socialse ha concentrado en la labor de mostraragremiación y de diseñar discursos perfectosaceptados hasta por los centros económicosy de poder, pero en la tarea de lograr transformacionesque cambien el rumbo de losacontecimientos, generando impacto social,los resultados son casi inexistentes. En estesentido, la pregunta que surge es si realmenteexisten los movimientos sociales, o son sóloproducto de una ficción que ha sido creadajustamente por las mismas élites de poderpermanente, que requieren de la revolucióny de la protesta como mecanismos para mantenerla esperanza en el pueblo, y con ella,sostener las ganas de vivir, las ganas de superaciónpersonal, y por ende, las ganas deconsumo
Fundamentals of Doing Business with Mexico: After the Exchange Control.
Abstract Forthcoming
Fundamentals of Doing Business with Mexico: After the Exchange Control.
Abstract Forthcoming
Concurrent chemo-radiotherapy following neoadjuvant chemotherapy in locally advanced breast cancer
<p>Abstract</p> <p>Background</p> <p>Despite broad advances in multimodal treatment of locally advanced breast cancer (LABC), 30 to 40% of patients develop loco-regional relapse. The aim of this study was to analyze in a retrospective manner the effectiveness of concurrent chemo-radiotherapy (CCRTh) after neoadjuvant chemotherapy (NCT) in patients with LABC.</p> <p>Methods</p> <p>One hundred twelve patients with LABC (stage IIB-IIIB) were treated with NCT (5-fluorouracil 500 mg/m<sup>2</sup>, doxorubicin 50 mg/m<sup>2</sup>, and cyclophosphamide 500 mg/m<sup>2 </sup>(FAC), or doxorubicin 50 mg/m<sup>2 </sup>and cyclophosphamide 500 mg/m<sup>2 </sup>(AC) IV in four 21-day courses) followed by CCRTh (60 Gy breast irradiation and weekly mitomycin 5 mg/m<sup>2</sup>, 5-fluorouracil 500 mg/m<sup>2</sup>, and dexamethasone 16 mg, or cisplatin 30 mg/m<sup>2</sup>, gemcitabine 100 mg/m<sup>2 </sup>and dexamethasone 16 mg), and 6–8 weeks later, surgery and two additional courses of FAC, AC, or paclitaxel 90 mg/m<sup>2 </sup>weekly for 12 weeks, and in case of estrogen-receptor positive patients, hormonal therapy.</p> <p>Results</p> <p>Stages IIB, IIIA and -B were 21.4, 42.9, and 35.7%, respectively. Pathological complete response (pCR) in the breast was 42% (95% CI, 33.2–50.5%) and, 29.5% (95% CI, 21.4–37.5%) if including both the breast and the axillary nodes. Multivariate analysis showed that the main determinant of pCR was negative estrogen-receptor status (HR = 3.8; 95% CI, 1.5–9; <it>p </it>= 0.016). The 5-year disease-free survival (DFS) was 76.9% (95% CI, 68.2–84.7%). No relationship between pCR and DFS was found. Multivariate analysis demonstrated that the main DFS determinant was clinical stage (IIB and IIIA <it>vs. </it>IIIB, HR = 3.1; 95% CI, 1.02–9.74; <it>p </it>= 0.04). Only one patient had local recurrence. Five-year overall survival was 84.2% (95% CI, 75–93.2%). The toxicity profile was acceptable.</p> <p>Conclusion</p> <p>This non-conventional multimodal treatment has good loco-regional control for LABC. Randomized clinical trials of preoperative CCRTh following chemotherapy, in patients with LABC are warranted.</p
OC5 Project Phase II: Validation of Global Loads of the DeepCwind Floating Semisubmersible Wind Turbine
This paper summarizes the findings from Phase II of the Offshore Code Comparison,
Collaboration, Continued, with Correlation project. The project is run under the
International Energy Agency Wind Research Task 30, and is focused on validating the
tools used for modeling offshore wind systems through the comparison of simulated
responses of select system designs to physical test data. Validation activities such as
these lead to improvement of offshore wind modeling tools, which will enable the
development of more innovative and cost-effective offshore wind designs. For Phase II
of the project, numerical models of the DeepCwind floating semisubmersible wind
system were validated using measurement data from a 1/50th-scale validation campaign
performed at the Maritime Research Institute Netherlands offshore wave basin.
Validation of the models was performed by comparing the calculated ultimate and
fatigue loads for eight different wave-only and combined wind/wave test cases against
the measured data, after calibration was performed using free-decay, wind-only, and
wave-only tests. The results show a decent estimation of both the ultimate and fatigue
loads for the simulated results, but with a fairly consistent underestimation in the tower
and upwind mooring line loads that can be attributed to an underestimation of waveexcitation
forces outside the linear wave-excitation region, and the presence of
broadband frequency excitation in the experimental measurements from wind.
Participant results showed varied agreement with the experimental measurements
based on the modeling approach used. Modeling attributes that enabled better
agreement included: the use of a dynamic mooring model; wave stretching, or some
other hydrodynamic modeling approach that excites frequencies outside the linear wave
region; nonlinear wave kinematics models; and unsteady aerodynamics models. Also, it
was observed that a Morison-only hydrodynamic modeling approach could create
excessive pitch excitation and resulting tower loads in some frequency bands.This work was supported by the U.S. Department of Energy under Contract No. DEAC36-
08GO28308 with the National Renewable Energy Laboratory. Some of the
funding for the work was provided by the DOE Office of Energy Efficiency and
Renewable Energy, Wind and Water Power Technologies Office
Postepizootic Persistence of Venezuelan Equine Encephalitis Virus, Venezuela
Etiologic subtype IC of virus persists, 5 years after the major 1995 epidemic
Algunas evidencias de aplicación
Libro temático especializadoLa sustentabilidad también debe aplicarse al sistema de producción, buscando impulsar transformaciones graduales de los estilos y modelos productivos tradicionales a unas de mayor eficiencia. Y donde se incorpore la dimensión ambiental y geográfico-espacial, para crear estructuras productivas más progresivas y equitativas en las sociedades. Todo esto, como alternativa para revertir las tendencias de escasez y agotamiento de los recursos naturales, así como de los desequilibrios globales, cuyos costos permean todos los tejidos humanos. De esta manera, la “sustentabilidad productiva” se concibe como la generación de bienes y servicios con ciertos estándares de calidad, bajo un esquema de eficiencia, rendimiento y de organización inclusiva e integrada, con baja presión al ambiente y uso racional de los recursos, garantizando la estadía y permanencia de los insumos y materiales en el tiempo. Desde esta perspectiva, la producción sustentable y el crecimiento de largo plazo pueden ser explicados por la capacidad que tienen las economías para generar e incorporar conocimientos y tecnologías. De ahí que, la educación y las cualificaciones del capital humano, los cambios en la organización de la producción y la calidad institucional, sean elementos nodales para avanzar en la consolidación de este ambiente productivo
Corporate social responsibility, engagement, burnout and satisfaction with life in an NGO in Colombia
La salud mental es una de las principales áreas de
interés en el marco de bienestar social y en el contexto
organizacional. En este sentido, se ha convertido en un
reto para las organizaciones no gubernamentales que
contribuyen al sector de economía de los servicios
sociales, alcanzar un equilibrio entre dos aspectos
íntimamente relacionados como lo son la salud y el
servicio a la comunidad. Este artículo tuvo como
objetivo describir la responsabilidad social corporativa,
el engagement y la satisfacción con la vida en una
muestra de 57 colaboradores de una ONG colombiana.
Los participantes completaron el Maslach Burnout
Inventory, la Escala de Satisfacción con la Vida y la
Encuesta de Adicción al Trabajo. Los resultaron
arrojaron que el engagement en el trabajo, está
directamente relacionado con actitudes positivas hacia
las tareas laborales y en la satisfacción de vida.Mental health is one of the main areas of interest within the framework of social welfare and the organizational
context. In this sense, it has become a challenge for non-governmental organizations that contribute to the
social services economy sector, striking a balance between two closely related aspects such as health and
community service. This article aimed to describe corporate social responsibility, engagement and
satisfaction with life in a sample of 57 employees of a Colombian NGO. Participants filled the Maslach Burnout
Inventory, Life Satisfaction Scale and Work Addiction Survey. The results showed that engagement at work is
directly related to positive attitudes towards work tasks and the satisfaction with life
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