113 research outputs found
Relationship between seasonal weather variation and students’ academic performance in Kaduna State University, Nigeria
The study assessed the relationship between seasonal weather variation and students’ academic performance in Kaduna State University (KASU), Kaduna State, Nigeria. The study involved the two campuses of KASU in Kaduna and Kafanchan. Academic Performance data was obtained from the academic office, meteorological data was obtained from NiMET while survey data was obtained using a structured questionnaire administered to 309 randomly selected student’. Data was analyzed using descriptive statistics and the Z – test Statistic. The study found out that seasonal weather variations occur in an academic session as revealed by NiMET data (2008 - 2018) and affected the academic performance of majority of the students (180) 58.3% negatively while (129)41.7% were not affected. The study recommended that mitigation and coping measures should be instituted during the second semester which coincides with peak rainfall to reduce its negative effect on students’ academic performance and a new calendar which avoids the peak weather periods in August, January and April should be designed and utilized as soon as possible to improve students’ academic performance in KASU
Entangled-Photon Generation from Parametric Down-Conversion in Media with Inhomogeneous Nonlinearity
We develop and experimentally verify a theory of Type-II spontaneous
parametric down-conversion (SPDC) in media with inhomogeneous distributions of
second-order nonlinearity. As a special case, we explore interference effects
from SPDC generated in a cascade of two bulk crystals separated by an air gap.
The polarization quantum-interference pattern is found to vary strongly with
the spacing between the two crystals. This is found to be a cooperative effect
due to two mechanisms: the chromatic dispersion of the medium separating the
crystals and spatiotemporal effects which arise from the inclusion of
transverse wave vectors. These effects provide two concomitant avenues for
controlling the quantum state generated in SPDC. We expect these results to be
of interest for the development of quantum technologies and the generation of
SPDC in periodically varying nonlinear materials.Comment: submitted to Physical Review
29. No association between MTHFR C677T polymorphism and congenital heart disease in Saudi Arabian population
Congenital heart diseases (CHD) are the most common birth defects in the world. It is a major cause of childhood mortality and morbidity worldwide with about 7 per 1000 live birth. Studies suggest that Methylenetetrahydrofolate reductase (MTHFR) polymorphism C667T has been associated with congenital malformation; this common missense mutation in the MTHFR gene may reduce enzymatic action, and may be involved in the etiology of congenital heart defects (CHD), but the evidence remains inconclusive. The aim of this study is to determine whether this association exists in the Saudi Arabian population.MethodDNA sequencing was used to detect genotype MTHFR C677T in 75 CHD patients and 100 ethnically similar controls. The type of cardiac defect was diagnosed by cardiovascular specialist and confirmed by echocardiographic.ResultsThe distribution of the MTHFR 677C >T SNP genotypes and alleles in both CHD and control groups were 70.0% CC, 26.0% CT, 4.0% TT in cases and 70.8% CC, 25.4% CT, 3.8% TT in controls. The T allele frequency was 17.0% in cases and 16.5% in controls. The difference between genotypes and alleles was not statistically significant between controls and the CHD groups.ConclusionWe did not find sufficient evidence for an association between MTHFR C677T genotype and congenital heart disease in Saudi Arabian population. We agree that the sample size is a limitation to our above conclusions
Quantum spiral bandwidth of entangled two-photon states
We put forward the concept of quantum spiral bandwidth of the spatial mode
function of the two-photon entangled state in spontaneous parametric
downconversion. We obtain the bandwidth using the eigenstates of the orbital
angular momentum of the biphoton states, and reveal its dependence with the
length of the down converting crystal and waist of the pump beam. The
connection between the quantum spiral bandwidth and the entropy of entanglement
of the quantum state is discussed.Comment: 10 pages, 3 figure
Entanglement, Mixedness, and Spin-Flip Symmetry in Multiple-Qubit Systems
A relationship between a recently introduced multipartite entanglement
measure, state mixedness, and spin-flip symmetry is established for any finite
number of qubits. It is also shown that, within those classes of states
invariant under the spin-flip transformation, there is a complementarity
relation between multipartite entanglement and mixedness. A number of example
classes of multiple-qubit systems are studied in light of this relationship.Comment: To appear in Physical Review A; submitted 14 May 200
A multi-photon Stokes-parameter invariant for entangled states
We consider the Minkowskian norm of the n-photon Stokes tensor, a scalar
invariant under the group realized by the transformations of stochastic local
quantum operations and classical communications (SLOCC). This invariant is
offered as a candidate entanglement measure for n-qubit states and discussed in
relation to measures of quantum state entanglement for certain important
classes of two-qubit and three-qubit systems. This invariant can be directly
estimated via a quantum network, obviating the need to perform laborious
quantum state tomography. We also show that this invariant directly captures
the extent of entanglement purification due to SLOCC filters.Comment: 9 pages, 0 figures, Accepted for publication in Physical Review
TBCRC 002: A phase II, randomized, open-label trial of preoperative letrozole with or without bevacizumab in postmenopausal women with newly diagnosed stage 2/3 hormone receptor-positive and HER2-negative breast cancer
Background: In preclinical studies, the expression of vascular endothelial growth factor (VEGF) in hormone receptor-positive breast cancer is associated with estrogen-independent tumor growth and resistance to endocrine therapies. This study investigated whether the addition of bevacizumab, a monoclonal antibody against VEGF, to letrozole enhanced the antitumor activity of the letrozole in the preoperative setting. Methods: Postmenopausal women with newly diagnosed stage 2 or 3 estrogen and/or progesterone receptor-positive, HER2-negative breast cancer were randomly assigned (2:1) between letrozole 2.5 mg PO daily plus bevacizumab 15 mg/kg IV every 3 weeks (Let/Bev) and letrozole 2.5 mg PO daily (Let) for 24 weeks prior to definitive surgery. Primary objective was within-arm pathologic complete remission (pCR) rate. Secondary objectives were safety, objective response, and downstaging rate. Results: Seventy-five patients were randomized (Let/Bev n = 50, Let n = 25). Of the 45 patients evaluable for pathological response in the Let/Bev arm, 5 (11%; 95% CI, 3.7-24.1%) achieved pCR and 4 (9%; 95% CI, 2.5-21.2%) had microscopic residual disease; no pCRs or microscopic residual disease was seen in the Let arm (0%; 95% CI, 0-14.2%). The rates of downstaging were 44.4% (95% CI, 29.6-60.0%) and 37.5% (95% CI, 18.8-59.4%) in the Let/Bev and Let arms, respectively. Adverse events typically associated with letrozole (hot flashes, arthralgias, fatigue, myalgias) occurred in similar frequencies in the two arms. Hypertension, headache, and proteinuria were seen exclusively in the Let/Bev arm. The rates of grade 3 and 4 adverse events and discontinuation due to adverse events were 18% vs 8% and 16% vs none in the Let/Bev and Let arms, respectively. A small RNA-based classifier predictive of response to preoperative Let/Bev was developed and confirmed on an independent cohort. Conclusion: In the preoperative setting, the addition of bevacizumab to letrozole was associated with a pCR rate of 11%; no pCR was seen with letrozole alone. There was additive toxicity with the incorporation of bevacizumab. Responses to Let/Bev can be predicted from the levels of 5 small RNAs in a pretreatment biopsy. Trial registration: This trial is registered with ClinicalTrials.gov (Identifier: NCT00161291), first posted on September 12, 2005, and is completed
Evidence for a mixed mass composition at the `ankle' in the cosmic-ray spectrum
We report a first measurement for ultra-high energy cosmic rays of the
correlation between the depth of shower maximum and the signal in the water
Cherenkov stations of air-showers registered simultaneously by the fluorescence
and the surface detectors of the Pierre Auger Observatory. Such a correlation
measurement is a unique feature of a hybrid air-shower observatory with
sensitivity to both the electromagnetic and muonic components. It allows an
accurate determination of the spread of primary masses in the cosmic-ray flux.
Up till now, constraints on the spread of primary masses have been dominated by
systematic uncertainties. The present correlation measurement is not affected
by systematics in the measurement of the depth of shower maximum or the signal
in the water Cherenkov stations. The analysis relies on general characteristics
of air showers and is thus robust also with respect to uncertainties in
hadronic event generators. The observed correlation in the energy range around
the `ankle' at differs significantly from
expectations for pure primary cosmic-ray compositions. A light composition made
up of proton and helium only is equally inconsistent with observations. The
data are explained well by a mixed composition including nuclei with mass . Scenarios such as the proton dip model, with almost pure compositions, are
thus disfavoured as the sole explanation of the ultrahigh-energy cosmic-ray
flux at Earth.Comment: Published version. Added journal reference and DOI. Added Report
Numbe
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