14 research outputs found
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Exploring digital teaching tools, including the use of social media, to support teaching; perspectives of M.Pharm. students
- Publication venue
- Publication date
- 01/01/2018
- Field of study
Background: The School of Pharmacy and Medical
Sciences, University of Bradford, is keen to evaluate the
potential benefits of digital tools to enhance the teaching
and learning of all M.Pharm. students. Students are
increasingly using digital technology for both educational
and social purposes (Cheston et al., 2013). This project
explored the views of pharmacy students about digital
technology, including social media, for teaching in the
M.Pharm. programme.
Method: Convenience sampling was employed to recruit
M.Pharm. students for focus groups. Each focus group,
facilitated by student researchers with topic guide, was
audio-recorded and analysed for themes. Ethics approval
was obtained from the University.
Results: Year 2 and 3 students from two focus groups
(n1=8 (6 male), n2=10 (8 male)) identified three main
digital teaching tools used in the current programme:
Blackboard, response clickers, and iSTAN. Blackboard, a
virtual learning environment, was seen as a hub for
holding all required learning materials. However, its use
depended on internet access and some felt they would
benefit from offline use and improved compatibility with
different devices. Audience response systems and a
human patient stimulator were well received by students.
However, participants strongly felt that they were underutilised.
The main benefit of using social media for learning was
instant feedback and the encouragement of informal
discussions. Participants were not always comfortable
posting within the current digital tools used in the
programme (e.g. Blackboard) as they felt ‘monitored’.
However, participants acknowledged that information
obtained through social media might not be as reliable as
information from digital tools moderated by academics.
Interestingly, participants reported a lack of engagement
with programme specific social media pages (e.g.
Facebook page). They felt that the information provided
was aimed at qualified pharmacists, rather than current
students.
Conclusion: Participants valued accessibility, flexibility
and availability of instant feedback when using digital
tools to support their learning. They felt positive about
the digital tools used within the programme but
emphasised the need of greater integration.
References
Cheston, C.C., Flickinger, T.E. & Chisom, M.S. (2013). Social
media use in medical education: a systematic review. Academic
Medicine, 88(6), 893-90
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial
- Author
- Aamir Afridi
- Aamir Ghafoor
- Aamir Husain
- Aasia Kayani
- Aasia Kayani
- Aasim Yusuf
- Abby Harper-Payne
- Abby Oglesby
- Abdelmounem Abdo
- Abdelmounem Eltayeib Abdo
- Abdul Wahid
- Abdus Khan
- Abid Ali
- Abrar Shaikh
- Achuth Shenoy
- Adam Bailey
- Adamu Ahmed
- Adamu Samaila
- Adedayo Oluyomi Tade
- Adeel Afzal
- Adeela Irfan
- Adeeqa Aman
- Adefemi Afolabi
- Adefemi Afolabi
- Adefemi Afolabi
- Adefemi Afolabi
- Adegboyega Akere
- Adegboyega Akere
- Adeleke Adekoya
- Ademola Tolulope Adebanjo
- Adewale Aderounmu
- Adil Chang
- Adnan Amin
- Adrian Barry
- Adrian Boyle
- Adrian Cotirlet
- Adrian Stanley
- Ahmad Taj
- Ahmed Shaker
- Aijaz Ahmed
- Aiman Mushir
- Ajay Adhikaree
- Ajay Adhikaree
- Akande Ajayi
- Alan Barkun
- Alastair Stevenson
- Alexander Atiri
- Alexandra Newman
- Alison Jefferey
- Alistair McNair
- Amanda Cowton
- Amanda Whileman
- Amber Geer
- Ameet Kumar
- Aminu Nahuche
- Amir Khan
- Amjad Ali
- Amjad Hussain
- Amy Brenner
- Amy Brenner
- Anam Bangash
- Andee Zakaria
- Andrei Ragea
- Andrei Voiosu
- Andrew Allison
- Andrew Appelboam
- Andrew Brown
- Andrew Dongo
- Andrew Kinnon
- Andrew Thayne
- Andrew Veitch
- Andrew Veitch
- Andrew Veitch
- Angiy Michael
- Anna Quinn
- Anne Hayes
- Anthony Kehoe
- Anu Mitra
- Anu Mitra
- Anuj K.C.
- Arben Beqiri
- Areej Al Balkhi
- Aroudra Outtandy
- Ashraf Helmy
- Asifa Aslam
- Avril Kuhrt
- Avto Megreladze
- Aye-Aye Thi
- Azeberoje Osueni
- Baadur Mosidze
- Barbara Watkins
- Ben Rayner
- Bernadette Gallagher
- Bernard Ndungu
- Besik Melikidze
- Beverley Faulkner
- Blasi
- Bobby Wellsh
- Bobby Wellsh
- Bogdan Busuioc
- Bogdan Mateescu
- Brenner
- Brenner
- Bukola Fawole
- Bukola Fawole
- Camelia Chioncel
- Carly Swann
- Carolyn Hughes
- Carrie Demetriou
- Catherine Gilliam
- Catherine Jarvis
- Catriona Bryceland
- Charlotte Owen
- Chelci Squires
- Chigozirim Onyekpere
- Chris Gough
- Chris Macdonald
- Chris Metcalfe
- Chris Roukas
- Christiane Vorwerk
- Christine Lambe
- Christopher Ekwunife
- Christopher Hawkey
- Claire Burnett
- Claire Dowty
- Coats
- Colin Bergin
- Collette Barrow
- Conor Deasy
- Conor Deasy
- Cook
- Courtenay Howe
- Daisy Mackle
- Dalia Ahmed
- Daniel Balaban
- Daniel Gilbert
- Daniel Hetherington
- Daniel Marks
- Daniel Pearson
- Daniela Manno
- Daniela Manno
- Danielle Beaumont
- Danielle Prowse
- Daniyan Muhammad
- David Hartin
- David Henry
- David Hobday
- David I'anson
- David Yeo
- Davit Kazaishvili
- Dawn Trodd
- Diane Simpson
- Donogh Maguire
- Dorina Pestroiu Calescu
- Edith Nonyelum Okeke
- Edries Tejan
- Edward Hartley
- Elaine Hardy
- Elaine Ng
- Emma Austin
- Emma Stoddard
- Emuobor Odeghe
- Enadeghe Eghaghe
- Eni Balogun
- Essa Khan
- Fady Nagy
- Faheem Butt
- Fazal Rahman
- Felicia Onoviran
- Fionn Bellis
- Folasade Adenike Bello
- Folasade Adenike Bello
- Frank Coffey
- Funmilola Wuraola
- Gabrielle May
- Gavin Wright
- Gayle Clifford
- Geoffrey Bellhouse
- Geoffrey Bellhouse
- Georgia Bercades
- Georgina Butt
- Ghias Tayyab
- Gia Tomadze
- Gluud
- Haider Zaigham Baqai
- Hakim Miah
- Haleema Shakur-Still
- Haleema Shakur-Still
- Haleema Shakur-Still
- Hamza Arshad
- Hannah Cotton
- Haroon Zahoor
- Hearnshaw
- Heather Jarman
- Helen Sweeting
- Helio Fornieles Pérez
- Holly Maguire
- Hussein Khamis
- Hussein Khamis
- Ian Gilmore
- Ian Gilmore
- Ian Roberts
- Ian Roberts
- Ian Roberts
- Ian Roberts
- Imogen Brooks
- Imogen Skene
- Imogen Skene
- Iram Saeed
- Irshad Hussain
- Irshad Hussain
- Isobel Bradbury
- Iulia Pintilie
- Jack Cuzick
- Jackie Berry
- Jacob de Wolff
- James East
- James Gagg
- James Shutt
- James Turvill
- Jamie Barbour
- Jane Hunt
- Jane Martin
- Janet Johnstone
- Jason Kendall
- Jason Klein
- Jason Pott
- Javaria Khan
- Jayne Foot
- Jeff Keep
- Jemma Tanner
- Jennifer Small
- Jiffre Din
- Joanna Tambellini
- Joanne Thunder
- Joaquin Alvarez Gregori
- Joaquín Álvarez Gregori
- John Greenaway
- John Jones
- Jonathan Simmons
- Jonathan Simmons
- Jonathon Snook
- Jordi Margalef
- Julia Grahamslaw
- Julian Humphrey
- Julie Tregonning
- Julio Gil Onandia
- Junaid Mushtaq
- Jung Ryu
- Kate Clayton
- Katharine Ker
- Katharine Ker
- Kay Finney
- Kehinde Osisanya
- Kelly Needham
- Kelvin Voon
- Kenneth Halligan
- Kenneth Halligan
- Khairul Azis
- Khalid Mahmood Nasir
- Khalid Yahya
- Khushboo Priya
- Kiran Bal
- Kiran Javaid
- Kiran Javaid
- Kris Pillay
- Laura Carrington
- Laura Hunter
- Laura O'Rourke
- Laura Ranopa
- Lauren Frimley
- Lecker
- Lee Joon
- Lisa McClelland
- Lisa Sawers
- Lisman
- Louisa Chan
- Louisa Chan
- Louise Chandler
- Lucian Negreanu
- Lucy Jones
- Lucy Parker
- Luke Lawton
- Luke Lawton
- Lynsey Flowerdew
- Madeleine Cargill
- Maggie Bell
- Majid Soomro
- Majid Soomro
- Mandy Grocutt
- Mansoor Ahmad
- Mansoor Ul Haq
- Maqbool Reki
- Marcel Tanău
- Maria Price
- Maria Ramos
- Mariam Hassan
- Mariana Jinga
- Marion McNaught
- Marium Waqar
- Martin James
- Martin Thomas
- Mary Doona
- Marzouqah Al Anazi
- Masykurin Mafauzy
- Matthew Banks
- Matthew Reed
- Matthew Rutter
- Mazen Naga
- Mia Reid
- Miland Joshi
- Mobeen Kayani
- Mohammad Hisyam
- Mohammad Jahit
- Mohammad Khalid
- Mohammad Shukri Bin Jahit
- Mohammad Zaher
- Mohammed Abdel Monem
- Mohammed Ashfaq
- Mohsin Ali
- Monday Yilkudi
- Monica Arribas
- Monica Arribas
- Morten Draegebo
- Mostafa Saiid
- Mouzam Shaikh
- Muhammad Afzal
- Muhammad Arif Nadeem
- Muhammad Arif Nadeem
- Muhammad Imran
- Muhammad Ishfaq
- Muhammad Khurram
- Muhammad Muaaz
- Muhammad Nasir
- Muhammad Qamar
- Muhammad Shafi
- Muhammad Umar
- Muhammad Zubair
- Muhyuddin Brukan
- Mujahid Aslam
- Mumtaz Marwat
- Muttiullah Mutti
- Muttiullah Mutti
- Muttiullah Mutti
- Muttiullah Mutti
- Myles
- Myriam Benyahia
- Nadeem Iqbal
- Naeem Aslam
- Nancy Ukwu
- Natasha Christmas
- Nayia Golfi
- Nicholas Watson
- Nick Mathieu
- Nicola Haeger
- Nicola Jacques
- Nicola Palmer
- Nigel Quashi
- Nigel Trudgill
- Nigel Trudgill
- Nighat Fatima
- Nil Amri
- Nino Grubelashvili
- Nizam Hashim
- Noureen Misbah
- Oakland
- Oguamanam Okezie Enwere
- Okafor Nnaemaka
- Ola Afolabi
- Oladapo Olayemi
- Oladapo Olayemi
- Olatunji Shonoiki
- Olawale Badejo
- Olivia Boulton
- Olu Orugun
- Olufunmilayo Lesi
- Olujide Okunade
- Olukayode Arowolo
- Olusade Adetayo
- Oluwole Olaomi
- Omar Ashoush
- Omer Omer
- Paul Cumpstay
- Paul Jhalli
- Peter Swallow
- Phil Edwards
- Phil Edwards
- Philip Boger
- Philip Devereaux
- Philip Kaye
- Pinkey Sachdev
- Quratul ain Ghalib
- Rachel Atkins
- Rachel Comer
- Rachel O'Brien
- Racquel Carpio
- Radu Bogdan Mateescu
- Raghavendra Kamath
- Rajaventhan Srirajaskanthan
- Raoul Mansukhani
- Raoul Mansukhani
- Richard Gray
- Richard Jackson
- Richard Pollok
- Richard Pollok
- Rita Das
- Rizwana Chaudhri
- Rizwana Chaudhri
- Rizwana Chaudhri
- Rob Jackson
- Roberts
- Roberts
- Romaih Al-Idari
- Rosalyn Squire
- Rose Ugiagbe
- Rufina Igetei
- Ruhama Uddin
- Ruth Fazakerley
- Ruth Worner
- Ruxandra Oprita
- Saadia Noreen
- Saafan Saafan
- Saba Arshad
- Sadaf Sattar
- Saif Al-Nahhas
- Saif Al-Nahhas
- Saifullah Goraya
- Sajjad Ali
- Sajjad Yaqoob
- Saleh Channa
- Sally Beer
- Salman Azhar
- Samuel Guest
- Samuel McBride
- Samuel Olatoke
- Sana Shaikh
- Sandeep Kumar
- Sanjay Singh
- Santosh Kumar
- Sarah Hearnshaw
- Sarah Moreton
- Sarah Rounding
- Sarah Wilson
- Serag Esmat
- Sergey Kostrov
- Shafqat Iqbal
- Shahida Tarar
- Shaik Farid
- Shakur
- Shankar Baral
- Sharmeen Aslam
- Shazad Afzal
- Shehroze Khan
- Sheik Pahary
- Sheraz Saleem
- Sherbat Khan
- Shweta Gidwani
- Shyang Yee Lim
- Sian Davies
- Simon Barnes
- Simon Carley
- Simon Everett
- Simon Stanworth
- Simon Stanworth
- Simon Tucker
- Simona Bataga
- Sinead Helyar
- Sir Young Yam
- Sivakumar
- Sneha Kansagra
- Sohaib Ahmed
- Stanley
- Stephanie Bell
- Stephen Haig
- Stephen Hood
- Steve Goodacre
- Steven Barden
- Stuart Paterson
- Sue Wakeford
- Suresh David
- Susan Fowler
- Susan Thornton
- Susie Hardwick
- Syed Ahmad
- Syed Shah
- Taemi Kawahara
- Tahir Bashir
- Tahir Rizvi
- Tamar Gogichaishvili
- Tamar Gogichaishvili
- Tanveer Hussain
- Tanya de Weymarn
- Tayyab Akhter
- Tayyaba Saif
- Tazaeen Kazmi
- Tehseen Hameed
- Temitope Oke
- Thomas Bartram
- Tim Godfrey
- Timothy Coats
- Timothy Coats
- Timothy Harris
- Timothy Harris
- Timothy Harris
- Tinuola Fakoya
- Toafiq Raji
- Ton Lisman
- Tony Brady
- Tracey Johnston
- Tracey Pepple
- Tristan Dyer
- Ubedullah Bughio
- Uchenna Ijoma
- Umar Riaz
- van Leerdam
- Vania Loureiro
- Victoria Murray
- Vijay Sah
- Vijay Yadav
- Vipul Jairath
- Vipul Jairath
- Wajahat Shafi
- Wan Najmi
- Wasim Uddin
- Wojciech Sawicki
- Xin Yi
- Yasir Iqbal
- Zafar Iqbal Chaudhry
- Zakawat Rasheed
- Zeeshan Ali
- Zuhrirahimi Ramli
- Publication venue
- 'Elsevier BV'
- Publication date
- 18/06/2020
- Field of study
Background: Tranexamic acid reduces surgical bleeding and reduces death due to bleeding in patients with trauma.
Meta-analyses of small trials show that tranexamic acid might decrease deaths from gastrointestinal bleeding. We
aimed to assess the effects of tranexamic acid in patients with gastrointestinal bleeding.
Methods: We did an international, multicentre, randomised, placebo-controlled trial in 164 hospitals in 15 countries.
Patients were enrolled if the responsible clinician was uncertain whether to use tranexamic acid, were aged above the
minimum age considered an adult in their country (either aged 16 years and older or aged 18 years and older), and
had significant (defined as at risk of bleeding to death) upper or lower gastrointestinal bleeding. Patients were
randomly assigned by selection of a numbered treatment pack from a box containing eight packs that were identical
apart from the pack number. Patients received either a loading dose of 1 g tranexamic acid, which was added to
100 mL infusion bag of 0·9% sodium chloride and infused by slow intravenous injection over 10 min, followed by a
maintenance dose of 3 g tranexamic acid added to 1 L of any isotonic intravenous solution and infused at 125 mg/h
for 24 h, or placebo (sodium chloride 0·9%). Patients, caregivers, and those assessing outcomes were masked to
allocation. The primary outcome was death due to bleeding within 5 days of randomisation; analysis excluded patients
who received neither dose of the allocated treatment and those for whom outcome data on death were unavailable.
This trial was registered with Current Controlled Trials, ISRCTN11225767, and ClinicalTrials.gov, NCT01658124.
Findings: Between July 4, 2013, and June 21, 2019, we randomly allocated 12 009 patients to receive tranexamic acid
(5994, 49·9%) or matching placebo (6015, 50·1%), of whom 11 952 (99·5%) received the first dose of the allocated
treatment. Death due to bleeding within 5 days of randomisation occurred in 222 (4%) of 5956 patients in the
tranexamic acid group and in 226 (4%) of 5981 patients in the placebo group (risk ratio [RR] 0·99, 95% CI 0·82–1·18).
Arterial thromboembolic events (myocardial infarction or stroke) were similar in the tranexamic acid group and
placebo group (42 [0·7%] of 5952 vs 46 [0·8%] of 5977; 0·92; 0·60 to 1·39). Venous thromboembolic events (deep vein
thrombosis or pulmonary embolism) were higher in tranexamic acid group than in the placebo group (48 [0·8%] of
5952 vs 26 [0·4%] of 5977; RR 1·85; 95% CI 1·15 to 2·98).
Interpretation: We found that tranexamic acid did not reduce death from gastrointestinal bleeding. On the basis of our
results, tranexamic acid should not be used for the treatment of gastrointestinal bleeding outside the context of a
randomised trial
Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic
- Author
- 14 | COVIDSurg COllabOratIVe Tzovaras G. (General University Hospital of Larissa)
- Aawsaj Y.
- Abad Gurumeta A.
- Abad-Motos A.
- Abate E.
- Abbott D.
- Abdalla M.
- Abdeldayem H.
- Abdelkader Salama I.
- Abdelkarim M.
- Abdur-Rahman L.
- Abel M. K.
- Aboelkassem Ibrahim A.
- Abou Chaar M. K.
- Abreu da Silva A.
- Abubakar A.
- Acebes García F.
- Achalandabaso Boira M. Sales Mallafré R. (Hospital Universitari de Tarragona Joan XXIII)
- Acher A.
- Acrich E.
- Adamina M.
- Aderombi A.
- Adeyeye A.
- Adiamah A.
- Afonso J.
- Agapov M.
- Agnes A.
- Agostini C.
- Agresta F.
- Aguado H. (Hellín Hospital)
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- Ahmed Z.
- Ahmeidat A.
- Ahn J. H.
- Aiken T.
- Aimé A.
- Akalin M.
- Akaydin E.
- Akhtar M. A.
- Akhter Rahman M. M.
- Akin E.
- Al Awwad S.
- Al Habes H.
- Al Maadany F. S. (Al-Jalaa Hospital)
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- Al-Mohammad A.
- Alaa S.
- AlAamer O.
- Aladeojebi A.
- Alam F.
- Alawneh F. (King Hussein Cancer Center). Libya: Alkadeeki G.
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- Alhassan N.
- Ali M.
- Ali S.
- Aliyeva Z.
- Aljiffry M.
- Alma Mater Studiorum University of Bologna)
- Almeida A. C.
- Almeida J. I.
- Almeida-Reis R.
- Alnumani T. (King Fahad 16 | COVIDSurg COllabOratIVe General Hospital)
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- Alonso de la Fuente N. Jimenez Toscano M. (Hospital del Mar)
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- Alselaim N. (King Saud Bin Abdulaziz University for Health Sciences
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- Bhalla A.
- Bhangu A.
- Bhangu Aneel
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- Bianco F. (ASST Papa Giovanni XXIII – Bergamo)
- Bigelow B. (Johns Hopkins Hospital)
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- Biondi A.
- Bisagni P.
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- Campus Benjamin Franklin)
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- Capolupo G. T. Mazzotta E. (Policlinico Universitario Campus Bio Medico of Rome)
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- Cassinotti E. (Fondazione IRCCS Ca’ Granda – Ospedale Maggiore Policlinico di Milano)
- Castellammare di Stabia)
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- Cervera I.
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- Chessa A.
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- Perotto L. O.
- Perra T.
- Persiani R.
- Pertile D.
- Petrillo A.
- Petropoulos K.
- Peyroteo M.
- Pezzuto A. P.
- Peña Ros E.
- Phan D. Townend D. (Lismore Base Hospital)
- Phillips E.
- Picardo A. L.
- Pickett L. (Connolly Hospital Blanchardstown)
- Picón Rodríguez R.
- Pieniowski E. (Stockholm South General Hospital)
- Piessen G.
- Pieve Emanuele (Mi))
- Pina S.
- Pinto J. Tojal A. (Centro Hospitalar Tondela-Viseu)
- Pipitone Federico N. S. (Edoardo Agnelli)
- Pisani Ceretti A. (ASST Santi Paolo E. Carlo)
- Pisanu A.
- Pizarro M. J.
- Pizzini P. (Ospedale Maggiore di Lodi)
- Pla Marti V. (Hospital Clínico Universitario de Valencia)
- Poch C.
- Pockney P. (John Hunter Hospital)
- Podda M. (Cagliari University Hospital)
- Poggioli G.
- Polydorou A.
- Popoola A. (University of Ilorin Teaching Hospital). Pakistan: Jamal A.
- Porcu A.
- Portinari M.
- Posadas-Trujillo O. E.
- Posma-Bouman L. (Slingeland Ziekenhuis)
- Potter R. (Royal Bournemouth Hospital)
- Pourcher G.
- Pozotou I.
- Praetorius C.
- Prando D.
- Presl J.
- Price C.
- Prieto Calvo M.
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- Provozina A. (Immanuel Kant Baltic Federal University
- Pruvot F. R.
- Pérez Sánchez M. A.
- Pérez-Saborido B.
- Qasem A. (Al- Basheer Hospital)
- Qatora M. S.
- Quante M.
- Qureshi A.
- Raby-Smith W.
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- Rakvin I. (Zadar General Hospital). Cyprus: Frantzeskou K.
- Ramachandran A. (Tunbridge Wells Hospital)
- Ramamoorthy 18 | COVIDSurg COllabOratIVe R.
- Ramcharan S.
- Ramesh P.
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- Rashid A. (SMHS Hospital
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- Razafindrahita J. B.
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- Rega D.
- Regional Clinical Hospital)
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- Richards T.
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- Righini E. (Azienda Unità Sanitaria Locale di Ferrara
- Riley C.
- Rimonda R.
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- Romano M.
- Romero de Diego A.
- Ronellenfitsch U. (University Hospital Halle (Saale))
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- Rottoli M.
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- Royle T.
- Rozzano (Mi) and Humanitas University
- Rubio-Perez I.
- Ruivo A.
- Ruiz Escobar A. (Infanta Leonor University Hospital)
- Ruiz Soriano M.
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- Russ J.
- Rutegård M. (Umea University Hospital). Switzerland: Arigoni M.
- Rutherford D.
- Ruzzenente A.
- Ryan M. (University Hospital Waterford/University College Cork). Italy: Macina S. (ASST Mantua)
- Ryan É. (University Hospital Galway)
- Ryska O. (Royal Lancaster Infirmary)
- Río Lafuente F. D.
- Saad M. M.
- Saafan T.
- Saavedra J.
- Sabah)
- Sabratha)
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- Sagnotta A. (Ospedale San Filippo Neri)
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- Salimoğlu S.
- Salindera S.
- Sallam I.
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- Samkari A.
- Sammarco G.
- Sammour T. (Royal Adelaide Hospital)
- Sampaio da Nóvoa Gomes Miguel I. I. (Centro Hospitalar Universitário do Algarve – Unidade de Portimão)
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- San Francisco (UCSF))
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- Sartarelli L.
- Sarveswaran J.
- Sasapu K. (Diana Princess of Wales Hospital Grimsby)
- Sasia D.
- Saudí S. (Hospital Universitario Miguel Servet)
- Sauvain M. (Pourtales Neuchatel Hospital)
- Sauvat F. (CHU Réunion). Romania: Bezede C.
- Savković N.
- Sayyed R. (Patel Hospital)
- Scabini S.
- Scalabre A. (Chu Saint Etienne)
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- Schiavo M. (Ospedale Vittorio Emanuele III – Carate Brianza)
- Schiergens T.
- Schineis C. (Charité University Medicine
- Schizas D.
- Schlesinger N.
- Schwartz P.
- Scott L. (Pinderfields Hospital)
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- Scrima O.
- Sechenov Medical State University)
- Seebah K.
- Seeliger B. (Strasbourg University Hospitals/IHU-Strasbourg)
- Seguin-Givelet A.
- Sehgal T.
- Selmani J.
- Semina E. (Moscow Research and Educational Center
- Senossi O.
- Serevina O. L.
- Serralta de Colsa D. (Infanta Sofía University Hospital)
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- Seymour Z. (Ysbyty Gwynedd). USA: Haynes A.
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- Sgrò A.
- Shah J. (North Manchester General Hospital)
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- Shaikh I.
- Shaikh S.
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- Sharma P. (Aberdeen Royal Infirmary)
- Shehata S.
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- Sheridan K.
- Sherief M.
- Sherif A. (Misr Cancer Center)
- Sherif A. E. (National Liver Institute
- Sherif G. (National Cancer Institute)
- Shokuhi P.
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- Sian T.
- Sibilla M. G.
- Sidiropoulos T.
- Silva M.
- Silva N.
- Silva R.
- Silveira Nunes I.
- Simões J. (Centro Hospitalar e Universitário de Coimbra)
- Singh A.
- Singh S. (Queen’s Hospital Romford)
- Skrovina M.
- Smith C.
- Smith H. (Bispebjerg Hospital). Egypt: Al Sayed M.
- Smith L.
- Smith. J (St James’s Hospital)
- Soares A. P.
- Soh J. Y.
- Sohrabi C.
- Solari F.
- Soriero D. (IRCCS Ospedale Policlinico San Martino)
- Sorrentino L. (Fondazione IRCCS Istituto Nazionale dei Tumori
- Sorribas Grifell M.
- Soto Montesinos C. (Fundació Althaia – Xarxa Assistencial Universitària de Manresa)
- Souadka A. (Institut National d’Oncologie
- Soulikia K.
- Sousa Fernandes M. (Hospital Beatriz Angelo)
- Sousa R. (Centro Hospitalar Universitário Lisboa Central)
- Sousa S.
- Spagni G.
- Spampinato M. G. (Vito Fazzi
- Spartalis E.
- Spencer N.
- Spiezio G. (Colorectal Surgical Oncology Unit – Istituto Nazionale Tumori Fondazione
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- Sreedharan L.
- Sriram R. K.
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- St John S.
- Stafford J. (George Eliot Hospital)
- Stavrinidou O.
- Steele C. (Sheffield Teaching Hospital NHS Foundation Trust)
- Steidle C.
- Steinke J.
- Stevens K.
- Stevenson J. (The Ottawa Hospital). Croatia: Bačić G.
- Stevic D.
- Stewart K. E.
- Stylianides N. (Manchester Royal Infirmary)
- Stylianidis G. (Evaggelismos General Hospital)
- Subhi M. T. (Alkhadra Hospital)
- Subocius A.
- Subramaniam S. (Queen Elizabeth Hospital and Universiti Malaysia Sabah
- Sundaram Venkatesan G. (Glan Clwyd Hospital)
- Suszták N. (Szent Borbála Kórház). India: Bhat G. A.
- Sutherland A. (Coffs Harbour Health Campus)
- Swinson B. (Royal Brisbane and Women’s Hospital). Austria: Messner F.
- Syed W. A. S.
- Syllaios A.
- Szatmary P.
- Szubota I. (Hospital and Oncological Centre Novy Jicin). Denmark: Ebbehøj A. L.
- Sánchez del Pueblo C.
- Sánchez Fuentes N.
- Sánchez- Pernaute A.
- Sánchez- Rubio M.
- Sánchez-García S.
- Taddei A.
- Tadic B.
- Taibi A. (Chu Limoges)
- Talal El-Abur I.
- Talwar R. (Luton and Dunstable University Hospital)
- Tammaro P.
- Tan J. A.
- Tan X. S.
- Tanal M.
- Tang A. M.
- Tanzanu M.
- Tartaglia D. (Azienda Ospedaliero Universitaria Pisana)
- Tasis N. (Athens Naval and Veterans Hospital)
- Tatar O. C.
- Tavares F.
- Tayeh S. (Homerton University Hospital)
- Tebala G. D.
- Teixeira J. (Centro Hospitalar Universitário do Algarve – Unidade de Faro)
- Teixeira M. (Centro Hospitalar do Tamega e Sousa)
- Tejero- Pintor F. J. (Hospital Universitario Río Hortega)
- Testa V. (Santa Croce E. Carle Hospital
- Tewari N. (University Hospitals Coventry and Warwickshire NHS Trusts)
- Tezas S. (Furness General Hospital)
- Thaha M.
- Thanapal M. R. (Hospital Kuala Lumpur)
- Theodosopoulos T.
- Theophilidou E. (Royal Derby Hospital)
- Thian A.
- Thomas A. (Royal Liverpool University Hospital)
- Thompson D. (Morriston Hospital Swansea)
- Thornhill M. (Dell Seton Medical Center at the University of Texas)
- Thrumurthy S. (Epsom and St Helier University Hospitals NHS Trust)
- Thulasiraman S. V.
- Timbrell S.
- Tirloni L.
- Titu S. (Prof. Dr. Ion Chiricuta Institute of Oncology). Russia: Garmanova T.
- Tonini V. (S. Orsola-Malpighi Hospital)
- Torres A. (Hospital Clínico de Madrid)
- Torres Arcos C.
- Townson A.
- Trabulsi N. (King Abdulaziz University Hospital)
- Travaglio E. (Regina Montis Regalis Hospital
- Tribillon E. (Institut Mutualiste Montsouris)
- Troncoso Pereira P. (Hospital Mateu Orfila)
- Tropeano F. P. (Federico II University Hospital)
- Trujillo Díaz J.
- Tsai L.
- Tsarkov P.
- Tsiamalou I.
- Tsiaoussis I.
- TU Dresden)
- Tucci R. (Azienda Ospedaliera Universitaria Careggi)
- Tufo A. (Ospedale del Mare)
- Tugmen C.
- Tulina I. (Clinic of Coloproctology and Minimally Invasive Surgery
- Tuncer K.
- Turnbull A. (Victoria Hospital Kirkcaldy)
- Turrado-Rodriguez V.
- Turri G. (Azienda Ospedaliera Universitaria Integrata di Verona)
- Tweedle E. (Addenbrooke’s Hospital)
- Ugarte-Sierra B. (Hospital Universitario de Galdakao)
- Uludağ S. S.
- Umair M.
- Universiti Sains Malaysia)
- University of Amsterdam)
- Università di Ferrara)
- Université Mohammed V Rabat). Netherlands: Hompes R.
- Uras C. (Acibadem Maslak Hospital)
- Urbani A. (Azienda Ospedaliero Universitaria San’anna)
- Urbieta A. (Hospital Universitario la Paz)
- Uslu G.
- Utkan N. Z.
- Uyanik M. S. (Samsun Training and Research Hospital)
- Uzunoglu F. G. (University Medical Center Hamburg–Eppendorf). Greece: Antonakis P.
- Vaccarella G. (Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello)
- Valbuena Jabares V. (Marqués de Valdecilla University Hospital)
- Valdes- Hernandez J. (Hospital Universitario Virgen Macarena)
- Valero Soriano M. (Hospital General Reina Sofía)
- Valle Rubio A. (Getafe University Hospital)
- Valverde S. (Hospital Clinic Barcelona)
- Van den Eynde J.
- Van den Eynde R. (Uz Leuven). Bulgaria: Sokolov M. (University Hospital Alexandrovska). Canada: Boutros M.
- Varma M. (University of California
- Vasljević J.
- Vassiliu P. (Attikon University General Hospital)
- Vaz Pereira R.
- Vaz S. (Centro Hospitalar e Universitário de São João)
- Velchuru V.
- Velickovic D. (Clinic for Digestive Surgery
- Velidedeoglu M.
- Venn M. (Royal London Hospital)
- Venskutonis D. (Lithuanian University of Health Sciences Kaunas Clinical Hospital). Madagascar: Rasoaherinomenjanahary F.
- Vera Mansilla C. (Hospital Universitario Principe de Asturias)
- Verberne C. (John Radcliffe Hospital)
- Vergari R. (Ospedali Riuniti di Ancona)
- Vernon L. (Cork University Hospital)
- Vervoort D.
- Vescio G. (University ‘Magna Graecia’ of Catanzaro)
- Vezakis A. (Aretaieion Hospital)
- Videira J. F. (IPO Porto). Réunion: Kassir R.
- Vieira B. (Centro Hospitalar de Trás-Os-Montes e Alto Douro
- Vieira Caroço T. (IPO Coimbra)
- Vieira Paiva Lopes A. C. (Hospital de Torres Vedras – Centro Hospitalar do Oeste)
- Vignali A. (San Raffaele Scientific Institute
- Vigorita V. (Álvaro Cunqueiro Hospital)
- Vijayan D. (Queen Elizabeth Hospital Birmingham)
- Villalabeitia Ateca I. (Hospital Universitario Cruces)
- Vimalachandran D. (Countess of Chester Hospital)
- Viswanath Y. K. S. (James Cook University Hospital)
- Vitali A. (Ospedale San Giovanni di Dio)
- Vitone L. (Royal Blackburn Hospital)
- Vives R. V. (Bellvitge University Hospital)
- Vo U. G. (Fiona Stanley Hospital)
- Von Papen M.
- Vovola F. (Ospedali Riuniti Azienda Ospedaliera Universitaria Foggia)
- Vucic N.
- Vázquez Fernández A. (Hospital Clínico Universitario de Valladolid)
- Wadham B. (The University Hospital of South Manchester)
- Walkes K. (Queen Elizabeth Hospital). Belgium: Flamey N.
- Wani R. (Sher-I-Kashmir Institute of Medical Sciences)
- Waqar S. H. (Pakistan Institute of Medical Sciences). Poland: Major P. (Jagiellonian University Medical College). Portugal: Azevedo C.
- Warren O. (Chelsea and Westminster Hospital)
- Watson L. J. (Sunderland Royal Hospital)
- Watson N. (King’s Mill Hospital)
- Weitz J.
- Welsch T. (Carl-Gustav-Carus University Hospital
- Werner J. (LMU Klinikum Campus Innenstadt)
- Westwood E. (James Paget University NHS Foundation Trust Hospital)
- Whelan M. (Tallaght University Hospital)
- Whitmore H. (Torbay and South Devon NHS Trust)
- Wilkin R. J. W. (South Warwickshire NHS Foundation Trust)
- Wilkins A. (Hull University Teaching Hospitals NHS Trust)
- Williams G. (Royal Gwent Hospital)
- Williams K. (St George’s Hospital)
- Wilson M. (Forth Valley Royal Hospital)
- Wimmer A. (Paracelsus Medical University Salzburg). Barbados: Barker D.
- Wong M.
- Worku D. (Queens Medical Centre)
- Wullschleger M. (Gold Coast University Hospital)
- Xavier R. G.
- Xenaki S.
- Xynos E. (University Hospital of Heraklion Crete and Interclinic Hospital of Crete). Hong Kong: Futaba K.
- Yang W.
- Yassin N. (Royal Wolverhampton NHS Trust)
- Ye G.
- Yesantharao P.
- Yetkin S. G. (Sisli Hamidiye Etfal Training and Research Hospital)
- Yeşilyurt D. (University of Health Sciences Tepecik Training and Research Hospital)
- Yiallourou A. (Nicosia General Hospital). Czechia: Martinek L.
- Yıldırım A.
- Yildiz A. (Yildirim Beyazit University Yenimahalle Training and Research Hospital). Uganda: Lule H.
- Young R. (York Teaching Hospitals NHS Trust)
- Yousof E. A. (Assiut University Hospital)
- Youssef M. (Norfolk and Norwich University Hospital)
- Yurttas C. (University Hospital Tuebingen)
- Yánez C. (Royo Villanova)
- Yüksel E. (Kocaeli University Teaching Hospital)
- Zafar S. N. (University of Wisconsin)
- Zakaria A. D.
- Zakaria Z. (School of Medical Sciences and Hospital
- Zambon M. (Policlinico Umberto I Sapienza University of Rome)
- Zanus G. (Ca’ Foncello Treviso – DISCOG – Università di Padova)
- Zegarac M. (Institute for Oncology and Radiology of Serbia)
- Zelić M. (University Hospital Center Rijeka)
- Zengin A. K. (Istanbul Universty – Cerrahpaşa Medical Faculty)
- Zerbib P. (CHU Lille)
- Zervas K.
- Zese M. (Santa Maria degli Angeli Hospital ULSS 5 – Adria)
- Zhang H. (Concord Repatriation General Hospital)
- Zizzo M. (Azienda Unità Sanitaria Locale – IRCCS di Reggio Emilia)
- Zografos C. (Laiko University Hospital)
- Zorrilla Ortúzar J. (Hospital General Universitario Gregorio Marañón)
- Zourntou S. (General Hospital of Larissa ‘Koutlimpaneio and Triantafylleio’)
- Zubaidi A. M. (King Saud University). Serbia: Aleksić L.
- Ângelo M.
- Çelebi F.
- Çolak E.
- Öfner D. (Medical University of Innsbruck)
- Öhlberger L.
- Özçelık M. F.
- Öğücü H.
- Überrück L.
- Ćoza I.
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2020
- Field of study
This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic
Eco-friendly synthesis of anti-microbial and anti-fungal binary metal oxide decorated reduced graphene oxide nanocomposites with complimenting density functional studies
- Author
- Publication venue
- Elsevier
- Publication date
- 01/09/2023
- Field of study
Recently, graphene-based nanocomposites are increasingly becoming popular for a variety of biological applications, due to their extraordinary physicochemical properties. Herein, we present an eco-friendly method for the preparation of a novel nanocomposite based on reduced graphene oxide (rGO) decorated with tin oxide (SnO2) and zinc oxide (ZnO) nanoparticles. The rGO and binary metal oxides-based nanocomposite (rGO/ZnO/SnO2) with enhanced biocompatibility was prepared by using Mentha longifolia extract as a non-hazardous reducing agent. The rich polyphenolic and flavonoids contents of Mentha longifolia have functioned as potential bio-reductants, which are not only suitable for the synthesis of rGO/ZnO/SnO2, but also effectively stabilized the resulting composite. Initially, to determine the reducing ability of Mentha longifolia, the redox potential and chemical composition of green extract was investigated by cyclic voltammetry (CV) and liquid chromatography-mass spectrometry (LC-MS), respectively. On the other hand, the structural composition and morphology of the resultant composite was confirmed by X-ray diffraction (XRD), Raman spectroscopy, Fourier transform infrared spectroscopy (FT-IR) and UV–visible spectroscopy (UV), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and energy-dispersive X-ray spectroscopy (EDS). Furthermore, the biological potential of rGO/ZnO/SnO2 is determined by evaluating the antimicrobial and antifungal properties of the resulting composite against various pathogens such as, Staphylococcus aureus (SA), Candida albicans (CA) and Clostridium dificile (CD). Notably, the composite has demonstrated superior antibacterial and antifungal properties when compared to its individual counterparts including rGO, SnO2 and ZnO. Density functional calculations complement the experimental findings, as the periodic boundary conditions reveal high binding energy of −14.8 keV for the rGO/ZnO/SnO2 nanocomposite
Histomorphological studies of broiler chicken fed diets supplemented with either raw or enzyme treated dandelion leaves and fenugreek seeds
- Author
- Publication venue
- 'Veterinary World'
- Publication date
- 01/03/2016
- Field of study
Aim: Herbal plants and their derived products are extensively used particularly in many Asian, African, and other countries of the world as they are considered as ideal feed additives because of their non-residual effect and ability to influence the ecosystem of gastrointestinal microbiota in a positive way. Further, the enzymatic treatment of these herbs helps in their efficient utilization by the host. Dandelion leaves and fenugreek seeds have been reported to have positive effect in terms of improving the performance of broiler chicken, but not much literature is available regarding their effect on gut histomorphology; therefore, the present study was conducted to explore the effect of these herbs either alone or in combination with or without enzyme treatment on histomorphology of liver and small intestine of broiler chicken.
Materials and Methods: To achieve the envisaged objective, 273-day-old commercial broiler chicks were procured from a reputed source and reared together until 7 days of age. On the 7th day, the chicks were individually weighed, distributed randomly into 7 groups of 3 replicates with 13 chicks each. Birds in the control group were fed diets without additives (T1). The other six treatment groups were fed the basal diet supplemented with 0.5% dandelion leaves (T2), 1% fenugreek seeds (T3), combination of 0.5% dandelion leaves and 1% fenugreek seeds (T4), enzyme treated dandelion leaves 0.5% (T5), enzyme treated fenugreek seeds 1% (T6), and combination of enzyme treated dandelion leaves (0.5%) and (1%) fenugreek seeds (T7). The histomorphological study of liver and small intestines was conducted among different treatment groups.
Results: The results revealed the hepato-protective nature of both dandelion leaves and fenugreek seeds either alone or in combination with or without enzyme treatment when compared with the control group. Moreover, the histomorphological findings of jejunum revealed the beneficial effect of dandelion leaves, fenugreek seeds and enzymes on the intestinal mucosa in terms of cellular infiltration, architecture of villi, villus height/crypt depth ratio, thereby improving the intestinal health.
Conclusion: The dandelion leaves and fenugreek seeds have hepato-protective nature and beneficial effect on the intestinal morphology particularly when included along with enzymes in the diet of broiler chicken
Open-Circuit Fault Detection in a Multilevel Inverter Using Sub-Band Wavelet Energy
- Author
- Publication venue
- MDPI AG
- Publication date
- 01/12/2021
- Field of study
Recent research has focused on sustainable development and renewable energy resources, thus motivating nonconventional cutting-edge technology development. Multilevel inverters are cost-efficient devices with IGBT switches that can be used in ac power applications with reduced harmonics. They are widely used in the power electronics industry. However, under extreme stress, the IGBT switches can experience a fault, which can lead to undesirable operation. There is a need for a reliable system for detecting switch faults. This paper proposes a signal processing method to detect open-circuit problems in IGBT switches. Relative wavelet energy has been used as a feature for a machine learning algorithm to diagnose and classify the faulted switches. The switching sequence can be altered to restore a healthy output voltage. Inverter faults have been diagnosed by using support vector machine (SVM) and decision tree (DT), and an ensemble model based on decision tree (DT) and XG boost algorithm was developed, which yielded 92%, 88%, and 94.12% accuracy, respectively
Global economic burden of unmet surgical need for appendicitis
- Author
- A A Essam
- Abd El-Rahman Hegazy Khedr
- Abd Elkhalek Sallam
- Abd Elrahman Elshafay
- Abdalla Gamal Saad
- Abdalla Gharib
- Abdalla Kenibar
- Abdallah Salah Elsherbiny
- Abdalrahman Adel
- Abdelaziz Abdelaal
- Abdelaziz Osman Abdelaziz Elhendawy
- Abdelfatah Hussein
- Abdelkader Belkouchi
- Abdelmalek Hrora
- Abdelrahman Adelshone
- Abdelrahman Alkammash
- Abdelrahman Assal
- Abdelrahman Geuoshy
- Abdelrahman Haroun
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- S S Prasad
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- Sahlu Wondimu
- Saiba Abdul-Latif
- Said Alyacoubi
- Sakhaa Hanoun
- Saleem El-Rabaa
- Saleh A Alnuqaydan
- Saleh Alqahtani
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- Sally Elshanwany
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- Samuel Sani Ali
- Sandip Kumar
- Sandra Ahlqvist
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- Sara Kharsa
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- Sarah Abdelghany
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- Saraibrahim Ahmed
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- Shaza Rabie Mohamed
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- Shorouk El Mesery
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- Shruti Ayyar
- Shu Ning Kong
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- Stefano M M Basso
- Stefano Roncali
- Stella Binna Kim
- Sten Saar
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- Stephanie Van Straten
- Stephen Dias
- Stephen J Chapman
- Stephen Kache
- Stephen Mcaleer
- Stephen R Knight
- Stephen Tabiri
- Steponas Petrikenas
- Stuart J Fergusson
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- Sudipta Roy
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- Susan Aviles
- Susan Limache
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- Susana Yrma Aranzabal Durand
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- Swantje Kruspi
- Swapnil Roy
- Syed Abdul Wahhab Eusoffee Wan Ali
- Syed Altaf Naqvi
- Syed Asaat Ul Razi
- Sylvia Batista Lemaire
- Sylvie Mochet
- Syrine Rekhis
- T Ariani Widiastini
- Tagang Ebogo Ngwa
- Taha Yusufali
- Taher Al-Taher
- Tahir Muhammad Yaseen
- Tahir Yaseen
- Tahira Naqvi
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- Taiwo Lawal
- Tan Arulampalam
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- Tapan Kumar
- Tara Grima
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- Tarek Razek
- Tasneem Idress
- Tasnia Hamid Kanta
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- Taufiq Khan
- Tebian Hassanein Ahmed Ali
- Tessa Fautz
- Tewodros Worku
- Thamer Nouh
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- Thea Dimech
- Thelma Tembo
- Thelma Xerri
- Theodore Pezas
- Theodosios Theodosopoulos
- Thiago Fernandes Giuriato
- Thierry Alihonou
- Thomas Feidantsis
- Thomas Fozard
- Thomas G Weiser
- Thomas M Drake
- Thomas Olagboyega Olajide
- Thomas Pinkney
- Thomas Prudhomme
- Thomas Sherman
- Thomas Tetens Moe
- Thuraya Alzayat
- Thusitha Sampath Hettiarachchi
- Tien Seng Bryan Lee
- Timothy White
- Tina Gaarder
- Tobias Schuetz
- Todisoa Emmanuella Christina Tolotra
- Tolg Cecilia
- Tom Am Malik
- Tom Arthur
- Tom Falconer Hall
- Tomas Abaliksta
- Tomas Jankus
- Tomas Poškus
- Tommaso Bocchetti
- Tommaso Campagnaro
- Tommaso Fontana
- Tony Mak
- Toqa Khafagy
- Torhild Veen
- Trude Beate Wold
- Tsz-Yan Katie Chan
- Tuan Nur'Azmah Tuan Mat
- Tunde Sholadoye
- Twc Mak
- Tyler Rouse
- Tzu-Ling Chen
- Uday Muddebihal
- Ufuk Karabacak
- Ulf Gunnarsson
- Ulf Gustafsson
- Umar Muktar
- Umberto Tedeschi
- Umme Salma
- Usama Hantour
- Uthman Alamoudi
- Valdemaras Jotautas
- Valentine Parent
- Vanessa Dina Palomino Castillo
- Vanessa Msosa
- Vania Guglielmo
- Vania Silvestri
- Vasileios Despotidis
- Vasileios Kalles
- Vasiliki Soulou
- Vassilis Kalles
- Veereanna Shatkar
- Venerand Barendegere
- Veronica Grassi
- Veronica Lazzari
- Vicky Jennings
- Victor Dassah
- Victor Etwire
- Victor Kong
- Victor Manuel Quintero Riaza
- Victor Nwinee
- Victoria K Proctor
- Vijaid Upadhyaya
- Vijay Gadhvi
- Viktorija Ambrozeviciute
- Viktorija Nevieraite
- Ville Sallinen
- Vimalakanthan Thanusan
- Vincas Jonas Banaitis
- Virgilijus Beisa
- Viviana Sollazzo
- Vivien Graffieille
- Vizir Jean Paul Nsengimana
- Vladimir Khokha
- Vollmer Sebastian
- Vu Thanh Hien Le
- Vytautas Gaižauskas
- Vytautas Lipnickas
- Wahid Anwer
- Wai Cheong Soon
- Wai Him Lam
- Wairimu Ndegwa
- Waleed Thabet
- Walid Adham
- Walter Forno
- Walter Ruiz Panez
- Wan Nurul 'Ain Wan Mohd Nasir
- Wanigasekara Senanayake Mudiyanselage Kithsiri Janakantha Senanayake
- Ward Hamsho
- Wasim Dar
- Wedyan Alhazmi
- Wei Guo
- Weiguang Ho
- Weihei Dao
- Wendy Leslie Messa Aguilar
- Wennweoi Goh
- Wifanto Saditya Jeo
- Wilfredo Pino
- William Appeadu-Mensah
- William Beasley
- William Bonney
- William Hutch
- William J Lossius
- William Milligan
- Willy Alcca Ticona
- Wing Sum Li
- Witold Chachulski
- Xavier Delforge
- Xianelle Rodriguez
- Xinwei Low
- Xue Wei Chan
- Ya Theng Neo
- Yacoubou Imorou Souaibou
- Yahaya Ukwenya
- Yahya Salama
- Yaseen Rajjoub
- Yasmein Ibrahim
- Yasmin Abd-Elrasoul
- Yasmin Elfouly
- Yasmin Hegazy
- Yasmin Soliman
- Yasser Abd El Salam
- Yee Wen Tan
- Yehia Zakaria
- Yella Reddy
- Yi Koon Tan
- Yi Ting Mok
- Yih Jeng Cheong
- Yiing Yee Gan
- Yishan Der
- Yogendra Praveen Mogan
- Yomna Allam
- Yomna Hosny Asar
- Yong Yong Tew
- Yousef Abuowda
- Yousra El Shoura
- Ysabel Esthefany Alejos Bermúdez
- Yuk Hong Eric Cheung
- Yuksel Altinel
- Yung Kok Ng
- Yuri Macchitella
- Yves Aigrain
- Yücel Cengiz
- Zaher Mikwar
- Zahra Jaffry
- Zain Ali Khan
- Zainab Iftikhar
- Zaynab M Elsayed
- Zhongtao Zhang
- Zi Hao Sam
- Zigmantas Urniežius
- Zilvinas Dambrauskas
- Zineb Bentounsi
- Zygimantas Tverskis
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2022
- Field of study
Background There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
Global economic burden of unmet surgical need for appendicitis
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Mohamed
- Abbasy Jibran
- Abbo Olivier
- Abbouch Meryem
- Abd-Elmawla Manar
- Abd-Elrasoul Yasmin
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdel-Wahab Nehal Yosri Elsayed
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- AbdelFattah Ibrahim
- Abdelgelil Asmaa
- Abdelghany Sarah
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkareem Ahmed
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraheim Mohamed
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshafy Mahmoud
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulbagi Omar
- Abdulgawad Mahmoud
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abebe Nebiyou Seyoum
- Abebe Nebyou Seyoum
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboarab Aya
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R.
- Aboraya Metwally
- Aboraya Mohammad
- Abouelnasr Alaa
- Aboul-Naga Mariam Saad
- Abouzahra Amany
- Abouzaid Arwa
- Abozaid Mohamed
- Abozeid Khaled
- Abozyed Mahmoud Ahmed Fathi
- Abu-toyour Maram
- Abubakr Marwan
- Abudeeb Haytham
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abuseif Mohamed
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Nourhan
- Adams Ryan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adekoya Adeleke
- Adel Abdalrahman
- Adel Ahmed
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji O
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesuyi Abidemi
- Adeyeye Ademola
- Adham Walid
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O
- Adnan Ahmad Bin
- Adu-Aryee Niiarmah
- Afana Samah
- Afandy Ahmed
- Afifi Ahmed Mohamed
- Africa South
- Agalianos Christos
- Agarwal Arnav
- Agbedinu Kwabena
- Agius Marija
- Aglan Amro
- Aguilar Wendy Leslie Messa
- Aguilar-Jimenez Jose
- Aguilera Maria Lorena
- Aguilera Omar
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahmed Ahmed
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Emad Ali
- Ahmed Hala
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahmed Soliman Magdy
- Ahounou Ernest Yemalin Stephane
- Aigrain Yves
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi E
- Ajiboye Anthony
- Akatibo Emmanuel
- Akeel Nouf
- Akoto Elliot
- Al-Aarag Asmaa Abdel-Rahman
- Al-Azraqi Israa Abdullah Aziz
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-Faifi Jubran J
- Al-faqawi Maha
- Al-farram Hadeel
- Al-Hameedi Hasan Ismael Ibraheem
- Al-Hasani Ruqaya Kadhim Mohammed Jawad
- Al-khatib Ahmed
- Al-Mallah Abdullah
- Al-Marakby Dina
- Al-Mousa Mashael
- Al-Nahrawi Safwat
- Al-Obaedi Ossama
- Al-saqqa Sara
- Al-Saqqa Sara W
- Al-shammari Abeer
- Al-Slaibi Ibrahim
- Al-taher Taher
- Alada Muslimat
- Alahmady Omar
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Alamoudi Uthman
- Albeladi Bandar
- Albiety Adel
- Aldalaq Ahmad
- Aldhafeeri Salman
- Aledrisy Mohannad
- Alexander Philip
- Alexandre Challine
- Alfarsi Muayad Ahmed
- Alghamdi Ahmed
- Alghamdi Basim
- Alghamdi Masood
- Alghamdi Mohammed Saleh A.
- Algohary Osama
- Alhabli Ibrahim
- Alhady Khaled
- Alhassan Basmah
- Alhazmi Wedyan
- Alhendy Mohammed
- Alherz Mohammad
- Ali Ahmad
- Ali Ahmed
- Ali Ased
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Farah Mahmoud
- Ali Hussein
- Ali Safia
- Ali Samuel Sani
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Alihonou Thierry
- Alimi Quentin
- Aliyu Halima
- Aliyu Mohammad
- Aliyu Shamsudeen
- Aljboor Khaled
- Aljiffry Murad
- Aljohani Emad
- Aljohani Saud
- Alkaaki Aroub
- Alkammash Abdelrahman
- Alkelani Muhammad
- Alkhabbaz Dalia
- Allam Meran
- Allam Mostafa
- Allam Yomna
- Allegri Andrea
- Allen John Lee Y
- Almallah Ahmad
- Almanon Christel Leanne
- Almoflihi Abdullah
- Almuallem Sultan
- Almy Jack
- Alnaby Mohamed Hassab
- Alnawam Ehab
- Alnuqaydan Saleh A.
- Alnusairat Aseel
- Alomar Ibrahim N.
- Alqahtani Enas
- Alqahtani Saleh
- Alrahawy Mahmoud
- Alrajraji Mawaddah
- Alrifaie Ahmad
- AlRowais Mohammed
- Alsaggaf Mohammed
- Alsaggaf Mohammed Ubaid
- Alser Osaid H.
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
- Altamimi Afnan
- Altamini Afnan
- Altarayra Marwa
- Althwainy Amani
- Altibi Ahmed
- Altinel Yuksel
- Altoe Fernanda
- Altwigry Abdulrahman M.
- Altwijri Abdulaziz
- Alvarez Ismael Isaac Zelada
- Alvi Abdul Rehman
- Alwafai Mohammad Ghassan
- Aly Abouelatta Khairy
- Aly Mohammed Yahia Mohamed
- Alyacoubi Said
- Alyahya Reem
- Alyami Rifan
- AlYoussef Ibrahim
- Alzahrani Ahmed
- Alzahrani Mohammed
- Alzayat Thuraya
- Aman Nowrin F.
- Amandito Radhian
- Ambrozeviciute Viktorija
- Ameen Mohamed
- Amer Mohamed A
- Amin Hager Abdul Aziz
- Amin Jasim
- Amin Shadid Al
- Amjad Mohammadasim
- Ammar Mohamed
- Ammar Mohamed Sabry
- Amoah Michael
- Amoako Joachim
- Amoako Philip Taah
- Amoako-Boateng Mabel
- Amole Isaac
- Amreia Mahmoud
- Anderson-Knight Hannah
- Andersson Linda
- Andika Ferry Fitriya Ayu
- Andreotti Dario
- Angelieri Daniele
- Anis Echaieb
- Ansaloni Luca
- Antar Sarah
- Antezana Diego
- Anthoulakis Christos
- Antoniozzi Angelo
- Anwar Abdul Wahid
- Anwar Nourhan
- Anwer Wahid
- Anyanwu Lofty-John
- Aonzo Paolo
- Appeadu-Mensah William
- Appiah Eric Kofi
- Aql Shaimaa
- Aquilino Fabrizio
- Arachchi Prasad Pitigala
- Arachchige Lalith Asanka Jayasooriya Jayasooriya
- Arafa Omar
- Arafa Sara
- Arango Maria Clara Mendoza
- Araujo Rafael
- Arcudi Claudio
- Ardley Rohan
- Arenas Andy
- Aristizã¡bal Fred Alexander Naranjo
- Arman Sam
- Armellini Andrea
- Arnaud Alexis Pierre
- Arshad Mohammad Mohsin
- Arsyad Hasbi Maulana
- Arthur Tom
- Arulampalam Tan
- Aruldas Neerav
- Asal Mohamed
- Asar Yomna Hosny
- Asare-Bediako Kwasi
- Asele Frehun Ayele
- Ashal Gehad El
- Ashour Ahmad
- Ashour Khlood
- Ashtari Morvarid
- Ashton Annelisse
- Asi Fatema
- Asilah Siti Mohd Desa
- Assal Abdelrahman
- Assouto Pamphile A
- Asturias Sabrina
- Asumah Hamza
- Ata Ahmed
- Ata Ali Amin Ahmed
- Ata Aya Yehia
- Atiyeh Anwar
- Atkins Ebenezer Takyi
- Atkinson Kieran
- Atobatele Kazeem
- Attallah Noura A.
- Attar Samaa Mahmoud Al
- Attard Myranda
- Attia Attia
- Attia Attia Mohamed
- Augestad Knut Magne
- Aung Kyaw Phyo
- Austraite Aiste
- Aviles Susan
- Avoka Anthony
- Awad Israa
- Awad Sawsan Adel
- Awuku-Asabre Joseph
- Awwad Saad Al
- Ayad Sara
- Ayandipo Omobolaji O
- Ayyar Shruti
- Aziz Dayang Nita Abdul
- Aziz Mohamed Rezal Abdul
- Aziz Nora Abdul
- Azizeldine Mohammed G.
- Azmitia José René Arévalo
- Azzie Georges
- Azzis Olivier
- Baba Suleiman
- Bachri Houda
- Badawy Mahmoud
- Badenjki Mohamed Adel
- Badr Ahmed
- Badr Mohamed Fawzy Mahrous
- Badwi Nermin M
- Badwi Nermin Mohamed
- Badwy Assmaa
- Bahar Suraya
- Baheeg Mohamad
- Bailey Karen
- Baird Alan
- Bakhaidar Mohamad
- Bakr Ahmad
- Bakry Hesham Mohammed
- Bala Miklosh
- Balalis Dimitrios
- Baldacchino Matthew
- Balducci Genoveffa
- Balila Reem Mohammed Hassan
- Balkan Ali Zeynel Abidin
- Ball Alasdair
- Ballouhey Quentin
- Balmaceda Rubén
- Balogun Fatai
- Baltrunas Robertas
- Baluch Fatima
- Bamicha Anastasia
- Bamicha Athanasia
- Banaitis Vincas Jonas
- Bandoh Dickson
- Bani-Sadar Ahmad
- Banipal Gurpreet Singh
- Baraka Heba
- Barakat Sara Abd Elmageed
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- Venskutonis Donatas
- Venugopal Caranj
- Verjee Azmina
- Vermaas Maarten
- Veronese Ezio
- Vianna Julia Guasti Pinto
- Vicario Erika
- Vida Lucian Corneliu
- Vilčinskas Mantas
- Villa Roberta
- Villalobos Santiago
- Vimalachandran Dale
- Vincent Joe
- Violi Paola
- Višinskas Petras
- Vivekanantham Sayinthen
- Vlachogiorgos Apostolos
- Vollmer Sebastian
- Voulgaris Evangelos
- Wael Noha
- Wagener Mark
- Waleed Hamza
- Walędziak Maciej
- Walsh Michael
- Waqar Muhammad
- Warda Mahmoud
- Warren Oliver
- Waterman Ade
- Watts Anna
- Weber Beatrix
- Weber Per
- Weiser Thomas G
- Wheeler James
- Whitaker John
- White Timothy
- Whitehurst Katharine
- Wiborg Joachim
- Widiastini T Ariani
- Wild Jonathan R L
- Williams Omolara
- Wilson Ling
- Wilson Michael
- Witherspoon Paul
- Wogensen Fredrik
- Woin Evelina
- Wold Trude Beate
- Wolf Bernhard
- Wondimu Sahlu
- Wondoh Paul
- Wong Chee Siong
- Wong Chui Yee
- Wong Hong Yee
- Wood Greta
- Woodward Helen
- Worku Mengistu
- Worku Tewodros
- Wredberg Cecilia
- Wright Naomi J
- Xerri Thelma
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yaseen Tahir
- Yaseen Tahir Muhammad
- Yavuz Mehmet Ali
- Ye Joselyn
- Yeang Li Jing
- Yeo Lee Shi
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yip Chingwan
- Yip Sebastian Bernardo Shu
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yong Cheryl Ou
- Yong Guo Liang
- Youssef Daniel
- Youssef Haney
- Youssef Mohamed
- Youssif Jehad Hassan
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zachariades Dimitris-Christos
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zalabia Mohamed F
- Zamarin Kresimir
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zardab Ali
- Zegarra Sergio
- Zerihun Abebe Bekele
- Zhang Zhongtao
- Zheng Fei
- Zidan Hagar
- Zidan Mohamed
- Ziff Oliver
- Zil-E-Ali Ahsan
- Zohair Ahmed
- Zuber Markus
- Zulkifli Athirah
- Žilinskas Justas
- Žilinskienė Reda
- Žiubrytė Greta
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Background There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms
- Author
- Abbas Syed Ali
- Abdalasalam Sabriya
- Abdalhadi Alaa Abdalfattah
- Abdalla Fadlalla Asgad Osman
- Abdalla Naana Reyam
- Abdalla Walaa
- Abdalrheem Almthani Hamza
- Abdalsalam Ashraf
- Abdeewi Saedah
- Abdelgaum Esraa Hassan
- Abdelghafar Yomna Ali
- Abdelhalim Mohamed
- Abdelkabir Mohammed
- Abdelrahman Mohammedahmed Manahil Omer
- Abdelrahman Israa
- Abdelrhman Abdallahrs Asia Atif
- Abdukahil Sheryl Ann
- Abdulbaqi Lamees Adil
- Abdulhamid Salaheddin
- Abdulhamid Widyan
- Abdulkadir Nurul Najmee
- Abdullah Duha Milad
- Abdulwahed Eman
- Abdunabi Rawad
- Abe Ryuzo
- Abebrese Franklina Korkor
- Abel Laurent
- Abodina Ahmed Mohammed
- Abrous Amal
- Absil Lara
- Abu Salem Talat Ahmed
- Abusalama Abdurraouf
- Abuzaid Tareg Abdallah
- Acharya Subhash
- Acker Andrew
- Adam Elisabeth
- Adem Safia
- Ademnou Manuella
- Adewhajah Francisca
- Adrião Diana
- Ads Alaa Mohamed
- Adusei Amos Amoako
- Afum-Adjei Awuah Anthony
- Agbogbatey Melvin
- Ahmed Khalil Reham Abdelhamid
- Ahmed Mohamed Abdelaziz Ali Mostafa
- Ahmed Aya Mustafa
- Ahmed Musaab Mohammed
- Ahmed Shakeel
- Ainscough Kate
- Airlangga Eka
- Aisa Tharwat
- Aisha Ali
- Aisha Bugila
- Akimoto Takako
- Akmal Ernita
- Akwani Chika
- Al Ageel Saleh
- Al Qasim Eman
- Al-Aquily Mohammed
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Al-Saba'a Yousef
- Alajeeli Ahmed
- Alali Ahmed
- Alalqam Razi
- Alameen Aliya Mohammed
- Alaraji Zainab Ahmed
- Alaraji Zinah A.
- Albakry Khalid
- Albatni Safa
- Alberti Angela
- Aldabbourosama Osama
- Aldhalia Amer
- Aldoukali Abdulkarim
- Alegesan Senthilkumar
- Alessi Marta
- Alex Beatrice
- Alexandre Kévin
- Alflite Asil
- Alfoudri Huda
- Alhadad Qamrah
- Alhaddad Hoda Salem
- Alhouri Ahmad Nabil
- Alhouri Hasan
- Ali Mohammed Abdelmalek Awad
- Ali Adam
- Ali Imran
- Ali Syed Muneeb
- Alidjnou Kazali Enagnon
- Aljadi Mahmoud
- Aljamal Sarah
- Alkahlout Mohammed
- Alkaseek Akram
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Almasri Lana
- Almjersah Abdulrahman
- Alqandouz Raja Ahmed
- Alrfaea Walaa
- Alrifaee Moayad
- Alsaadi Rawan
- Alshareea Entisar
- Alshenawy Eslam
- Altaf Aneela
- Alves João
- Alves João Melo
- Alves Rita
- Alyasiri Mohammed Saleh
- Amaral Maria
- Amer Amro Essam
- Amira Nur
- Amuasi John
- Andini Roberto
- Andrejak Claire
- Angheben Andrea
- Angoulvant François
- Ankrah Sophia
- Ansari Muhammad Imran
- Ansart Séverine
- Anthonidass Sivanesen
- Antonelli Massimo
- Antunes de Brito Carlos Alexandre
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Arancibia Francisco
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Argin G.
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Ascofare Oumou Maiga
- Asensio Angel
- Ashley Elizabeth A.
- Ashraf Muhammad
- Ashraf Muhammad Sheharyar
- Asiedu-Bekoe Franklin
- Asif Namra
- Asim Mohammad
- Assi Grace
- Assie Jean Baptiste
- Asyraf Amirul
- Atangana Fouda
- Atia Ahmed
- Atif Minahel
- Atikah Ahmad Ridzuan Siti Nurul
- Atique Anika
- Atlowly Moad
- Attanyake AM Udara Lakshan
- Auchabie Johann
- Aumaitre Hugues
- Auvet Adrien
- Axelsen Eyvind W.
- Ayad Ared
- Ayadi Kamaluddin Muhammad Aisar
- Azemar Laurène
- Azizeldin Mohammed
- Azoulay Cecile
- Babatunde Hakeem
- Bach Benjamin
- Bachelet Delphine
- Badr Claudine
- Baig Nadia
- Baillie John Kenneth
- Baird J Kevin
- Bak Erica
- Bakakos Agamemnon
- Bakar Nazreen Abu
- Bakeer Hibah Bileid
- Bakri Ashraf
- Bal Andriy
- Balakrishnan Mohanaprasanth
- Bandoh Irene
- Banheiro Bruno Sarmento
- Bani-Sadr Firouzé
- Barbalho Renata
- Barbosa Nicholas Yuri
- Barclay Wendy S.
- Barnett Saef Umar
- Barnikel Michaela
- Barrasa Helena
- Barrigoto Cleide
- Bartoli Marie
- Baruch Joaquin
- Baruch Joaquín
- Basmaci Romain
- Basri Muhammad Fadhli Hassin
- Bassi Gianluigi Li
- Batool AbdAlkarim
- Battaglini Denise
- Bauer Jules
- Bautista Rincon Diego Fernando
- Beane Abigail
- Bedossa Alexandra
- Bedu-Addo Ama Kwakyewaa
- Bee Ker Hong
- Begum Husna
- Behilill Sylvie
- Beishuizen Albertus
- Bekken Gry Kloumann
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beltrão Beatriz Amorim
- Beluze Marine
- Ben Ashur Abir
- Benech Nicolas
- Benjiman Lionel Eric
- Bennett Suzanne
- Bento Luís
- Berdal Jan-Erik
- Berdeweel Lamis
- Bergeaud Delphine
- Bergin Hazel
- Bertoli Giulia
- Bertolino Lorenzo
- Bessis Simon
- Bevilcaqua Sybille
- Bezulier Karine
- Bhatt Amar
- Bhavsar Krishna
- Bianchi Isabella
- Bianco Claudia
- Bichoka Sandra
- Bidin Farah Nadiah
- Bin Kamarudin Mohd Nazlin
- Binnawara Muhannud
- Binti Mohd Yakop Siti Rohani
- Binti Zaidan Nor Zaila
- Bisoffi Zeno
- Biston Patrick
- Bitker Laurent
- Bittaye Mustapha
- Bitton Jonathan
- Blanco-Schweizer Pablo
- Blier Catherine
- Bloos Frank
- Blot Mathieu
- Boccia Filomena
- Bodenes Laetitia
- Bogaert Debby
- Boivin Anne-Hélène
- Bolanga Ariel
- Bolaños Isabela
- Bolze Pierre-Adrien
- Bompart François
- Bonifasius Aurelius
- Bonney Joe
- Borges Diogo
- Borie Raphaël
- Bosse Hans Martin
- Botelho-Nevers Elisabeth
- Bouadma Lila
- Bouchaud Olivier
- Bouchez Sabelline
- Boudoin Herwin Nanda
- Bouhour Damien
- Bouiller Kévin
- Bouillet Laurence
- Bouisse Camile
- Bountthasavong Latsaniphone
- Boureau Anne-Sophie
- Bourke John
- Bouscambert Maude
- Bousquet Aurore
- Boyer-Besseyre Marielle
- Boylan Maria
- Bozza Fernando Augusto
- Braconnier Axelle
- Braga Cynthia
- Brandenburger Timo
- Brazzi Luca
- Breen Dorothy
- Breen Patrick
- Brewster David
- Brickell Kathy
- Brien Fionnuala O.
- Broadley Tessa
- Brotherton Helen
- Browne Alex
- Brozzi Nicolas
- Brunvoll Sonja Hjellegjerde
- Brusse-Keizer Marjolein
- Bryda Petra
- Buchtele Nina
- Bugaeva Polina
- Buisson Marielle
- Buonsenso Danilo
- Burhan Erlina
- Buri Donald
- Burrell Aidan
- Bustos Ingrid G.
- Butnaru Denis
- Bævre-Jensen Roar
- Cabie André
- Cabral Susana
- Cabrita Joana
- Cabrita Joana Alves
- Caceres Eder
- Cadoz Cyril
- Callaghan Annmarie O.
- Calligy Kate
- Calvache Jose Andres
- Camões João
- Campana Valentine
- Campbell Paul
- Campisi Josie
- Canepa Cecilia
- Cantero Mireia
- Caoili Janice
- Caraux-Paz Pauline
- Cardoso Filipa
- Cardoso Filipe
- Cardoso Nelson
- Cardoso Sofia
- Carelli Simone
- Carlier Nicolas
- Carmoi Thierry
- Carney Gayle
- Carqueja Inês
- Carret Marie-Christine
- Carrier François Martin
- Carroll Ida
- Carson Gail
- Casanova Maire-Laure
- Cascão Mariana
- Casey Siobhan
- Casimiro José
- Cassandra Bailey
- Castanheira Nidyanara
- Castañeda Silvia
- Castor-Alexandre Guylaine
- Castro Ivo
- Catarino Ana
- Catherine François-Xavier
- Cattaneo Paolo
- Cavalin Roberta
- Cavalli Giulio Giovanni
- Cavayas Alexandros
- Cárcel Sheila
- Ceccato Adrian
- Ceesay Masaneh
- Cely Lina Morales
- Cerkovnik Shelby
- Cervantes-Gonzalez Minerva
- Cevik Muge
- Chair Anissa
- Chakveatze Catherine
- Chan Adrienne
- Chand Meera
- Chapplain Jean-Marc
- Charpentier Charlotte
- Chas Julie
- Chaudry Muhammad Mobin
- Chávez Iñiguez Jonathan Samuel
- Che Kamaruddin Zul Amali
- Chen Anjellica
- Chen Yih-Sharng
- Chenard Léo
- Cheng Matthew Pellan
- Cheret Antoine
- Chia Jack Song
- Chiarabini Thibault
- Chica Julian
- Chidambaram Suresh Kumar
- Chirouze Catherine
- Chiumello Davide
- Cho Sung-Min
- Choileain Orna Ni
- Cholley Bernard
- Chommanam Danoy
- Chopin Marie-Charlotte
- Chow Ting Soo
- Chow Yock Ping
- Christy Nathaniel
- Chua Hiu Jian
- Chua Jonathan
- Cidade Jose Pedro
- Cisneros Herreros José Miguel
- Citarella Barbara Wanjiru
- Citarella Barbara Wanjiru
- Ciullo Anna
- Clarke Jennifer
- Claure-Del Granado Rolando
- Clohisey Sara
- Codan Cassidy
- Cody Caitriona
- Coles Jennifer
- Coles Megan
- Colin Gwenhaël
- Collins Michael
- Combs Pamela
- Connolly Jennifer
- Connor Marie
- Conrad Anne
- Conway Elaine
- Cooke Graham S.
- Cordel Hugues
- Corley Amanda
- Cornelis Sabine
- Cornet Alexander Daniel
- Corpuz Arianne Joy
- Cortegiani Andrea
- Corvaisier Grégory
- Couffignal Camille
- Couffin-Cadiergues Sandrine
- Courtois Roxane
- Cousse Stéphanie
- Cowan Juthaporn
- Cregan Rachel
- Crowl Gloria
- Crump Jonathan
- Cruz Claudina
- Csete Marc
- Cullen Ailbhe
- Cummings Matthew
- Curley Gerard
- Curlier Elodie
- Curran Colleen
- Custodio Paula
- D'Alessandro Umberto
- D'Aragon Frédérick
- D'Ortenzio Eric
- da Silva Filipe Ana
- Da Silva Fernanda Dias
- Da Silveira Charlene
- Dabaliz Al-Awwab
- Dagens Andrew
- Dagens Andrew
- Dahl John Arne
- Dahly Darren
- Daley Peter
- Dalloul Zaina
- Dalton Heidi
- Dalton Jo
- Daly Seamus
- Damas Juliana
- Dame Joycelyn
- Damien Cammandji
- Daneman Nick
- Dantas Jorge
- de Loughry Gillian
- de Mendoza Diego
- De Montmollin Etienne
- de Piero Maria
- De Rosa Rosanna
- De Rose Cristina
- de Silva Thushan
- de Vries Peter
- Deacon Jillian
- Dean David
- Debard Alexa
- DeBenedictis Bianca
- Debray Marie-Pierre
- DeCastro Nathalie
- Dechert William
- Decours Romain
- Defous Eve
- Delacroix Isabelle
- Delamou Alexandre
- Delaveuve Eric
- Delavigne Karen
- Delfos Nathalie M.
- Deligiannis Ionna
- Dell'Amore Andrea
- Delmas Christelle
- Delobel Pierre
- Delsing Corine
- Demonchy Elisa
- Denis Emmanuelle
- Deplanque Dominique
- Depuydt Pieter
- Descamps Diane
- Desvallées Mathilde
- Devouge Eglantine Ferrand
- Dewayanti Santi
- Dhangar Pathik
- Diallo Alpha
- Diallo Souleymane Taran
- Diamantis Sylvain
- Dias André
- Diaz Juan Jose
- Diaz Priscila
- Diaz Rodrigo
- Dibba Bakary K.
- Didier Kévin
- Diehl Jean-Luc
- Dieperink Wim
- Dilanthi Priyadarshani Gamage Dona
- Dimet Jérôme
- Dinot Vincent
- Diop Fara
- Diouf Alphonsine
- Dishon Yael
- Djadda Cedric
- Djossou Félix
- Docherty Annemarie B.
- Doherty Helen
- Dominguez Carmen Infante
- Dondorp Arjen M.
- Donnelly Christl A.
- Donohue Sean
- Donohue Yoann
- Doran Peter
- Dorival Céline
- Doshi Yash
- Douangdala Phouvieng
- Douglas James Joshua
- Douma Renee
- Dournon Nathalie
- Dow Denisse Bazan
- Downey Joanne
- Downing Mark
- Drake Thomas
- Driscoll Aoife
- Duah Ibrahim Kwaku
- Dubee Vincent
- Dubos François
- Dubot-Pérès Audrey
- Ducancelle Alexandre
- Duculan Toni
- Dudman Susanne
- Duggal Abhijit
- Dunand Paul
- Dunning Jake
- Dunning Jake
- Duplaix Mathilde
- Durante-Mangoni Emanuele
- Durham Lucian
- Dussol Bertrand
- Duthoit Juliette
- Duval Xavier
- Dyrhol-Riise Anne Margarita
- Ean Sim Choon
- Ebo Ada
- Echeverria-Villalobos Marco
- Edelstein Michael
- Egan Siobhan
- Eggesbø Linn Margrete
- Ehzaz Khadeja
- Eira Carla
- Ekow Harrison Samuel Bernard
- El Sanharawi Mohammed
- El Sayed Marwan
- Elabid Mohammed
- Elagili Mohamed Bashir
- Elapavaluru Subbarao
- Elbahnasawy Mohammad
- Elboshra Sohail
- Elharrar Brigitte
- Elhefnawy Enan Abdulrahman Ahmed
- Eliza Mohamed Nik Nur
- Ellerbroek Jacobien
- Ellingjord-Dale Merete
- ELMagrahi Hamida
- Elmubark Mohammad Muatasm
- Elotmani Loubna
- Eloundou Lauren
- Eloy Philippine
- Elsayed Soliman Mohamed Osama
- Elshaikhy Basma
- Elshazly Tarek
- Elsokni Wafa
- Eltayeb Aml Ahmed
- Elyazar Iqbal
- Emad Zarief Kamel
- Embarek Hussein
- Enderle Isabelle
- Endo Tomoyuki
- Eneli Gervais
- Eng Chan Chee
- Engelmann Ilka
- Enouf Vincent
- Epaulard Olivier
- Esaadi Haneen
- Escher Martina
- Esperatti Mariano
- Esperou Hélène
- Esposito-Farese Marina
- Essaka Rachel
- Essuman Lorinda
- Estevão João
- Etienne Manuel
- Everding Anna Greti
- Evers Mirjam
- Fabre Isabelle
- Fabre Marc
- Fadera Ismaila
- Faheem Amna
- Fahy Arabella
- Fairfield Cameron J.
- Fakar Zul
- Fareed Komal
- Faria Pedro
- Farooq Ahmed
- Fateena Hanan
- Fathi Mohamed
- Fatima Salem
- Fatoni Arie Zainul
- Fatoni Arie Zainul
- Faure Karine
- Favory Raphaël
- Fayed Mohamed
- Feely Niamh
- Fernandes Henrique Mateus
- Fernandes Jorge
- Fernandes Marília Andreia
- Fernandes Marília Andreia
- Fernandes Susana
- Ferrand François-Xavier
- Ferraz Mário
- Ferrão Joana
- Ferreira Benigno
- Ferreira Bernardo
- Ferreira Isabel
- Ferreira Sílvia
- Ferriere Nicolas
- Ficko Céline
- Figueiredo-Mello Claudia
- Finlayson William
- Flament Thomas
- Fletcher Tom
- Florence Aline-Marie
- Florio Letizia Lucia
- Flynn Brigid
- Flynn Deirdre
- Foley Jean
- Fomin Victor
- Fonseca Claudio Duarte
- Fonseca Tatiana
- Fontela Patricia
- Forrest Karen
- Forson Paa Kobina
- Forsyth Simon
- Foster Denise
- Foti Giuseppe
- Fotso Berline
- Fourn Erwan
- Fowler Robert A.
- Fraher Marianne
- Franch-Llasat Diego
- França Rafael Freitas de Oliveira
- Fraser Christophe
- Fraser John F.
- Freire Marcela Vieira
- French Craig
- Friedrich Caren
- Fritz Ricardo
- Fry Stéphanie
- Fuentes Nora
- Fukuda Masahiro
- Gaborieau Valérie
- Gaci Rostane
- Gagliardi Massimo
- Gagnard Jean-Charles
- Gagneux-Brunon Amandine
- Gai Abdou
- Gaião Sérgio
- Galal Mohamed Ramadan Adham Mohamed
- Gallagher Phil
- Gamble Carrol
- Gandonniere Charlotte Salmon
- Gani Yasmin
- Garan Arthur
- Garcês Rui Caetano
- Garcia Rebekha
- Garcia-Diaz Julia
- Garcia-Gallo Esteban
- Garimella Navya
- Garot Denis
- Garrait Valérie
- Gauli Basanta
- Gavrylov Anatoliy
- Gaymard Alexandre
- Gebauer Johannes
- Geraud Eva
- Germano Nuno
- Ghemmeid Malak
- Ghisulal Praveen Kumar
- Ghosn Jade
- Giani Marco
- Gigante Tristan
- Gilroy Elaine
- Giordano Guillermo
- Girvan Michelle
- Gissot Valérie
- Giwangkancana Gezy
- Glikman Daniel
- Glybochko Petr
- Gnall Eric
- Goco Geraldine
- Goehringer François
- Goepel Siri
- Goffard Jean-Christophe
- Goh Jin Yi
- Golács Brigitta
- Golob Jonathan
- Gomez Kyle
- Gominet Marie
- Gonçalves Bronner P.
- Gonzalez Alicia
- Gordon Patricia
- Gorenne Isabelle
- Goubert Laure
- Goujard Cécile
- Goulenok Tiphaine
- Gómez-Junyent Joan
- Grable Margarite
- Graf Jeronimo
- Grandin Edward Wilson
- Granerud Beathe Kiland
- Granier Pascal
- Grasselli Giacomo
- Grazioli Lorenzo
- Green Christopher A.
- Greene Courtney
- Greenhalf William
- Greffe Segolène
- Grieco Domenico Luca
- Griffee Matthew
- Griffiths Fiona
- Grigoras Ioana
- Groenendijk Albert
- Grovogui Fassou Mathias
- Gruner Heidi
- Gu Yusing
- Guedj Jérémie
- Guego Martin
- Guerguerian Anne-Marie
- Guerreiro Daniela
- Guery Romain
- Guillaumot Anne
- Guilleminault Laurent
- Guimarães de Castro Maisa
- Guimard Thomas
- Haalboom Marieke
- Haber Daniel
- Hachemi Ali
- Haddud Abdurrahman
- Hadri Nadir
- Hafez Wael
- Haidri Fakhir Raza
- Haji Ab Rahman Ahmad Kashfi
- Hakak Sheeba
- Hall Adam
- Hall Matthew
- Hall Matthew
- Halpin Sophie
- Hamdan Shaher
- Hamdi Abdelhafeez
- Hameed Jawad
- Hamer Ansley
- Hamers Raph L.
- Hamidfar Rebecca
- Hammarström Bato
- Hammond Naomi
- Hammond Terese
- Han Lim Yuen
- Hanan Matly
- Haniffa Rashan
- Hao Kok Wei
- Hardwick Hayley
- Harrison Ewen M.
- Harrison Janet
- Hartman Alan
- Hasan Mohd Shahnaz
- Hasan Sulieman
- Hashmi Junaid
- Hashmi Madiha
- Hassan Helmi Ahmed Ayman
- Hassan Amoni
- Hassanin Ebtisam
- Hayat Muhammad
- Hayes Ailbhe
- Hays Leanne
- Heerman Jan
- Heggelund Lars
- Helmi Ahmed
- Hendry Ross
- Hennessy Martina
- Henriquez-Trujillo Aquiles Rodrigo
- Hentzien Maxime
- Hernandez Diana
- Hershey Andrew
- Hesstvedt Liv
- Hidayah Astarini
- Higgins Eibhlin
- Higgins Rupert
- Hing Nicholas Yee Liang
- Hinton Samuel
- Hiraiwa Hiroaki
- Hirkani Haider
- Hitoto Hikombo
- Ho Antonia
- Ho Yi Bin
- Hoctin Alexandre
- Hoffmann Isabelle
- Hoh Wei Han
- Hoiting Oscar
- Holt Rebecca
- Holten Aleksander Rygh
- Holter Jan Cato
- Horby Peter
- Horby Peter
- Horcajada Juan Pablo
- Houas Ikram
- Houderi Mabrouka
- Hough Catherine L.
- Houltham Stuart
- Hssain Ali Ait
- Hulot Jean-Sébastien
- Humaid Felwa Bin
- Hurd Abby
- Hussain Iqbal
- Hussein Aliae Mohamed
- Hussein Mahmood
- Ibáñez-Prada Elsa D.
- Ibrahim Fatima
- Ibran Bashir
- Ijaz Samreen
- Ikram M. Arfan
- Illana Carlos Cañada
- Imbert Patrick
- Inácio Hugo
- Ing Yun Sii
- Ippolito Mariachiara
- Irawany Vera
- Isabel de Pinho Oliveira Ana
- Isgett Sarah
- Isidoro Tiago
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- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Yuliarto Saptadi
- Zaaqoq Akram
- Zabbe Marion
- Zabert Gustavo E.
- Zacharowski Kai
- Zahid Masliza
- Zahran Maram
- Zambon Maria
- Zambrano Miguel
- Zanella Alberto
- Zaynah Nurul
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- Publication date
- 30/05/2024
- Field of study
Background: COVID-19 is primarily known as a respiratory illness; however, many patients present to hospital without respiratory symptoms. The association between non-respiratory presentations of COVID-19 and outcomes remains unclear. We investigated risk factors and clinical outcomes in patients with no respiratory symptoms (NRS) and respiratory symptoms (RS) at hospital admission. Methods: This study describes clinical features, physiological parameters, and outcomes of hospitalised COVID-19 patients, stratified by the presence or absence of respiratory symptoms at hospital admission. RS patients had one or more of: cough, shortness of breath, sore throat, runny nose or wheezing; while NRS patients did not. Results: Of 178,640 patients in the study, 86.4 % presented with RS, while 13.6 % had NRS. NRS patients were older (median age: NRS: 74 vs RS: 65) and less likely to be admitted to the ICU (NRS: 36.7 % vs RS: 37.5 %). NRS patients had a higher crude in-hospital case-fatality ratio (NRS 41.1 % vs. RS 32.0 %), but a lower risk of death after adjusting for confounders (HR 0.88 [0.83-0.93]). Conclusion: Approximately one in seven COVID-19 patients presented at hospital admission without respiratory symptoms. These patients were older, had lower ICU admission rates, and had a lower risk of in-hospital mortality after adjusting for confounders
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial
- Author
- Aamir Afridi (9020687)
- Aamir Ghafoor (7575572)
- Aamir Husain (9020810)
- Aasia Kayani (6164375)
- Aasim Yusuf (9020828)
- Abby Harper-Payne (9020537)
- Abby Oglesby (9020426)
- Abdelmounem Abdo (9021089)
- Abdelmounem Eltayeib Abdo (9020198)
- Abdul Wahid (4395094)
- Abdus Khan (5280116)
- Abid Ali (3123210)
- Abrar Shaikh (9020759)
- Achuth Shenoy (9020639)
- Adam Bailey (6013856)
- Adamu Ahmed (9020894)
- Adamu Samaila (9020909)
- Adedayo Oluyomi Tade (9020879)
- Adeel Afzal (9020822)
- Adeela Irfan (9020807)
- Adeeqa Aman (9020792)
- Adefemi Afolabi (7105229)
- Adegboyega Akere (3993119)
- Adeleke Adekoya (9020876)
- Ademola Tolulope Adebanjo (9020921)
- Adewale Aderounmu (9020861)
- Adil Chang (9020699)
- Adnan Amin (3340584)
- Adrian Barry (9020216)
- Adrian Boyle (3283776)
- Adrian Cotirlet (9021053)
- Adrian Stanley (7810184)
- Ahmad Taj (9020684)
- Ahmed Shaker (9020954)
- Aijaz Ahmed (4524742)
- Aiman Mushir (9020705)
- Ajay Adhikaree (9020195)
- Akande Ajayi (9020915)
- Alan Barkun (4392202)
- Alastair Stevenson (9020597)
- Alexander Atiri (9020870)
- Alexandra Newman (9020471)
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- Mandy Grocutt (9020579)
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- Mohammed Abdel Monem (9020966)
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- Mostafa Saiid (9020951)
- Mouzam Shaikh (9020795)
- Muhammad Afzal (83943)
- Muhammad Arif Nadeem (2863970)
- Muhammad Imran (282621)
- Muhammad Ishfaq (6700175)
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- Muhammad Muaaz (9020681)
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- Mujahid Aslam (9020693)
- Mumtaz Marwat (9020831)
- Muttiullah Mutti (7105235)
- Myriam Benyahia (9020084)
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- Wasim Uddin (9020780)
- Wojciech Sawicki (9020621)
- Xin Yi (180644)
- Yasir Iqbal (23922)
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- Zakawat Rasheed (9020804)
- Zeeshan Ali (5950430)
- Zuhrirahimi Ramli (9021002)
- Publication venue
- Publication date
- 20/06/2020
- Field of study
BackgroundTranexamic acid reduces surgical bleeding and reduces death due to bleeding in patients with trauma. Meta-analyses of small trials show that tranexamic acid might decrease deaths from gastrointestinal bleeding. We aimed to assess the effects of tranexamic acid in patients with gastrointestinal bleeding.MethodsWe did an international, multicentre, randomised, placebo-controlled trial in 164 hospitals in 15 countries. Patients were enrolled if the responsible clinician was uncertain whether to use tranexamic acid, were aged above the minimum age considered an adult in their country (either aged 16 years and older or aged 18 years and older), and had significant (defined as at risk of bleeding to death) upper or lower gastrointestinal bleeding. Patients were randomly assigned by selection of a numbered treatment pack from a box containing eight packs that were identical apart from the pack number. Patients received either a loading dose of 1 g tranexamic acid, which was added to 100 mL infusion bag of 0·9% sodium chloride and infused by slow intravenous injection over 10 min, followed by a maintenance dose of 3 g tranexamic acid added to 1 L of any isotonic intravenous solution and infused at 125 mg/h for 24 h, or placebo (sodium chloride 0·9%). Patients, caregivers, and those assessing outcomes were masked to allocation. The primary outcome was death due to bleeding within 5 days of randomisation; analysis excluded patients who received neither dose of the allocated treatment and those for whom outcome data on death were unavailable. This trial was registered with Current Controlled Trials, ISRCTN11225767, and ClinicalTrials.gov, NCT01658124.FindingsBetween July 4, 2013, and June 21, 2019, we randomly allocated 12 009 patients to receive tranexamic acid (5994, 49·9%) or matching placebo (6015, 50·1%), of whom 11 952 (99·5%) received the first dose of the allocated treatment. Death due to bleeding within 5 days of randomisation occurred in 222 (4%) of 5956 patients in the tranexamic acid group and in 226 (4%) of 5981 patients in the placebo group (risk ratio [RR] 0·99, 95% CI 0·82–1·18). Arterial thromboembolic events (myocardial infarction or stroke) were similar in the tranexamic acid group and placebo group (42 [0·7%] of 5952 vs 46 [0·8%] of 5977; 0·92; 0·60 to 1·39). Venous thromboembolic events (deep vein thrombosis or pulmonary embolism) were higher in tranexamic acid group than in the placebo group (48 [0·8%] of 5952 vs 26 [0·4%] of 5977; RR 1·85; 95% CI 1·15 to 2·98).InterpretationWe found that tranexamic acid did not reduce death from gastrointestinal bleeding. On the basis of our results, tranexamic acid should not be used for the treatment of gastrointestinal bleeding outside the context of a randomised trial.</div