Vida y sucesos prosperos y adversos de Don Fr. Bartolome de Carranza y Miranda, Arzobispo de Toledo ...

Sign.: A-O8ReclamosFriso xil

Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance

"Proteins with glycine-rich signatures have been reported in a wide variety of organisms including plants, mammalians, fungi, and bacteria. Plant glycine-rich protein genes exhibit developmental and tissue-specific expression patterns. Herein, we present the characterization of the AtGRDP2 gene using Arabidopsis null and knockdown mutants and, Arabidopsis and lettuce over-expression lines. AtGRDP2 encodes a short glycine-rich domain protein, containing a DUF1399 domain and a putative RNA recognition motif (RRM). AtGRDP2 transcript is mainly expressed in Arabidopsis floral organs, and its deregulation in Arabidopsis Atgrdp2 mutants and 35S::AtGRDP2 over-expression lines produces alterations in development. The 35S::AtGRDP2 over-expression lines grow faster than the WT, while the Atgrdp2 mutants have a delay in growth and development. The over-expression lines accumulate higher levels of indole-3-acetic acid and, have alterations in the expression pattern of ARF6, ARF8, and miR167 regulators of floral development and auxin signaling. Under salt stress conditions, 35S::AtGRDP2 over-expression lines displayed higher tolerance and increased expression of stress marker genes. Likewise, transgenic lettuce plants over-expressing the AtGRDP2 gene manifest increased growth rate and early flowering time. Our data reveal an important role for AtGRDP2 in Arabidopsis development and stress response, and suggest a connection between AtGRDP2 and auxin signaling.

Factores de riesgo asociados a enfermedad renal crónica en la población adulta en cuatro estratos socioeconómicos del municipio de Guatemala

Describir el comportamiento epidemiológico de los factores de riesgo asociados a enfermedad renal crónica, en la población adulta de cuatro estratos socioeconómicos del Municipio de Guatemala en abril 2015. Estudio de tipo descriptivo, transversal, con muestreo no probabilístico por conveniencia, en 4 sectores cartográficos, 223 viviendas. Los datos se recolectaron por medio de una encuesta con base al cuestionario del método progresivo (STEPS) modificado. La prevalencia de factores de riesgo modificables asociados a enfermedad renal crónica en población adulta, en 4 estratos socioeconómicos del municipio de Guatemala fue de:sedentarismo(76%),sobrepeso/obesidad (56%), consumo de sal (36%), presión arterial elevada (31%) consumo de bebidas artificiales (30%), consumo de alcohol (21%), consumo de tabaco (1%). La prevalencia de factores de riesgo no modificables asociados a enfermedad renal crónica en población adulta, en 4 estratos socioeconómicos del municipio de Guatemala fue de: antecedente médico de hipertensión (35%), antecedente médico de de hipercolesterolemia (17%) y antecedente de diabetes mellitus. (11%). los factores de riesgo de mayor prevalencia asociado a desarrollar enfermedad renal crónica fueron sedentarismo, sobrepeso/obesidad y consumo de sal. El comportamiento epidemiológico de los factores de riesgo asociados para el desarrollo ERC fue ser sexo femenino, estar entre el rango de edad de 40 a 60 años, con un estado civil de casado, haber terminado diversificado como nivel de escolaridad, pertenecer a la población trabajadora, tener ingresos económicos en el hogar menores a Q3,247.20 y pertenecer al grupo étnico ladino

The nation of the persecuted scholars, episcopaliam, heresy and historical memory in the Courts of Cadiz

RESUMEN: Estudio el debate sobre la Inquisición en las Cortes de Cádiz, teniendo en cuenta la influencia de los libros de Llorente o Puigblanch y la definición del concepto de herejía que se hizo por la Comisión de Constitución. Esto es lo que marcó la nueva visión del pasado español por parte de los diputados liberales. Fueron muy críticos con la Inquisición por sus procedimientos, pero mantuvieron el delito de herejía. De ese pasado quedaron excluidos los descendientes de «judíos» y «moros». Los nuevos «mártires» habían sido los teólogos, biblistas y escritores del XVI perseguidos por la Inquisición. Criticaron el proceso inquisitorial contra el arzobispo Carranza como ataque a la jurisdicción episcopal, poniéndole como ejemplo de prelado sabio y evangélico. Más que en principios liberales, el decreto de abolición de 22 de febrero de 1813 se inscribió en la lógica de propuestas radicales del reformismo del reformismo borbónico.ABSTRACT: I study the debate on the Inquisition in the Cortes of Cadiz, taking into account the influence of Llorente or Puigblanch books and the definition of the concept of heresy that was made by the Committee on Constitution. This is what marked the new vision of the Spanish past by Liberal members. They were very critical of the Inquisition because of their procedures, but they kept the crime of heresy. The descendants of «Jews» and «moros» were excluded from that past. The new «martyrs» were theologians, Biblical scholars and writers of the 16th persecuted by the Inquisition. They criticized the Inquisition against Archbishop Carranza as attack the episcopal jurisdiction, putting him as an example of wise and Evangelical prelate. More on liberal principles, Decree of abolition of February 22, 1813 he joined the logic of radical proposals for the reformism of the Bourbon reformism.Este trabajo se ha realizado en el marco del proyecto de investigación HAR 2015-6894-C3-1-P. “De reinos a naciones. Las transformaciones del sistema cortesano (Siglos XVIII-XIX)”

The Sensitivity of HAWC to High-Mass Dark Matter Annihilations

The High Altitude Water Cherenkov (HAWC) observatory is a wide field-of-view detector sensitive to gamma rays of 100 GeV to a few hundred TeV. Located in central Mexico at 19 degrees North latitude and 4100 m above sea level, HAWC will observe gamma rays and cosmic rays with an array of water Cherenkov detectors. The full HAWC array is scheduled to be operational in Spring 2015. In this paper, we study the HAWC sensitivity to the gamma-ray signatures of high-mass (multi- TeV) dark matter annihilation. The HAWC observatory will be sensitive to diverse searches for dark matter annihilation, including annihilation from extended dark matter sources, the diffuse gamma-ray emission from dark matter annihilation, and gamma-ray emission from non-luminous dark matter subhalos. Here we consider the HAWC sensitivity to a subset of these sources, including dwarf galaxies, the M31 galaxy, the Virgo cluster, and the Galactic center. We simulate the HAWC response to gamma rays from these sources in several well-motivated dark matter annihilation channels. If no gamma-ray excess is observed, we show the limits HAWC can place on the dark matter cross-section from these sources. In particular, in the case of dark matter annihilation into gauge bosons, HAWC will be able to detect a narrow range of dark matter masses to cross-sections below thermal. HAWC should also be sensitive to non-thermal cross-sections for masses up to nearly 1000 TeV. The constraints placed by HAWC on the dark matter cross-section from known sources should be competitive with current limits in the mass range where HAWC has similar sensitivity. HAWC can additionally explore higher dark matter masses than are currently constrained.Comment: 15 pages, 4 figures, version to be published in PR

Effective Synthesis Procedure Based on Microwave Heating of the PdCo Aerogel Electrocatalyst for Its Use in Microfluidic Devices

Unsupported PdCo aerogels were successfully synthesized by means of microwave heating. The use of this heating methodology provides some advantages compared to conventional heating in terms of saving synthesis time and improved physicochemical properties (i.e., greater surface area and mesoporosity). The combination of palladium with cobalt reduces the dependence of the noble metal and increases the electrocatalytic performance in the ethanol oxidation reaction due to a higher percentage of Pd0 in the PdCo aerogel, confirmed using the X-ray photoelectron spectroscopy (XPS) technique. For the application in energy conversion electrochemical systems, the catalytic activity of aerogels was evaluated in a microfluidic fuel cell that uses ethanol as fuel, where the PdCo aerogel synthesized by microwave heating exhibited great performance with 330 mA cm-2 current density, tripling the value of the palladium-based aerogel.The authors thank Consejo Nacional de Humanidades, Ciencias y Tecnologías (CONAHCYT) for funding through the Ciencia de Frontera 2020-845132.Peer reviewe

VAMOS: a Pathfinder for the HAWC Gamma-Ray Observatory

VAMOS was a prototype detector built in 2011 at an altitude of 4100m a.s.l. in the state of Puebla, Mexico. The aim of VAMOS was to finalize the design, construction techniques and data acquisition system of the HAWC observatory. HAWC is an air-shower array currently under construction at the same site of VAMOS with the purpose to study the TeV sky. The VAMOS setup included six water Cherenkov detectors and two different data acquisition systems. It was in operation between October 2011 and May 2012 with an average live time of 30%. Besides the scientific verification purposes, the eight months of data were used to obtain the results presented in this paper: the detector response to the Forbush decrease of March 2012, and the analysis of possible emission, at energies above 30 GeV, for long gamma-ray bursts GRB111016B and GRB120328B.Comment: Accepted for pubblication in Astroparticle Physics Journal (20 pages, 10 figures). Corresponding authors: A.Marinelli and D.Zaboro

Polymorphisms in the hypoxia-inducible factor 1 alpha gene in Mexican patients with preeclampsia: A case-control study

<p>Abstract</p> <p>Background</p> <p>Although the etiology of preeclampsia is still unclear, recent work suggests that changes in circulating angiogenic factors play a key role in its pathogenesis. In the trophoblast of women with preeclampsia, hypoxia-inducible factor 1 alpha (HIF-1α) is over-expressed, and induces the expression of non-angiogenic factors and inhibitors of trophoblast differentiation. This observation prompted the study of HIF-1α and its relation to preeclampsia. It has been described that the C1772T (P582S) and G1790A (A588T) polymorphisms of the <it>HIF1A </it>gene have significantly greater transcriptional activity, correlated with an increased expression of their proteins, than the wild-type sequence. In this work, we studied whether either or both <it>HIF1A </it>variants contribute to preeclampsia susceptibility.</p> <p>Results</p> <p>Genomic DNA was isolated from 150 preeclamptic and 105 healthy pregnant women. Exon 12 of the <it>HIF1A </it>gene was amplified by PCR, and the genotypes of <it>HIF1A </it>were determined by DNA sequencing.</p> <p>In preeclamptic women and controls, the frequencies of the T allele for C1772T were 4.3 vs. 4.8%, and the frequencies of the A allele for G1790A were 0.0 vs. 0.5%, respectively. No significant differences were found between groups.</p> <p>Conclusion</p> <p>The frequency of the C1772T and G1790A polymorphisms of the <it>HIF1A </it>gene is very low, and neither polymorphism is associated with the development of preeclampsia in the Mexican population.</p