Aczin selam vermediği diyar!:Türk mimarisine şeref veren koca Sinanın doğduğu köy

Taha Toros Arşivi, Dosya No: 171-Mimar Sinanİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN/0033

Beyond Muslim Xenophobia and Contemporary Parochialism: Aga Khan IV, the Ismā‘īlīs, and the making of a Cosmopolitan Ethic

Aga Khan IV is the forty-ninth hereditary Imām of the Shī‘a Nizārī Ismā‘īlī Muslims (or ‘Ismā‘īlīs’ for short). As a Muslim leader, Aga Khan IV addresses salient issues concerning humankind in the contemporary world and expresses the challenges of living under such conditions through his public speeches and the institutions of the Ismā‘īlī Imāmate. His discourse is informed by the inseparability of dīn (faith) and dunyā(world), which is viewed as being a central function to the office of Imāmate. Aga Khan IV adopts a context-rich approach that addresses modernity by integrating commitments to theology with religio-cultural ethics, a formulation that facilitates the engagement of the Ismā‘īlī community in the contemporary world. A key feature of Aga Khan IV’s worldview is a tolerant and cosmopolitan attitude with deep spiritual underpinnings, which appeals to a broad range of individuals, not just Ismā‘īlīs. This research situates and explains Aga Khan IV’s concept of a ‘cosmopolitan ethic’ within concerns of human diversity and understandings of the Self-Other paradigm in human narratives. I demonstrate how significant initiatives of Aga Khan IV promote a cosmopolitan ethic, helping to foster a moral sensibility among the Ismā‘īlīs and communities at large. A critical analysis of Aga Khan IV’s ‘cosmopolitan ethic’ is undertaken through the consideration of broader discourses and experiences of cosmopolitanism throughout history. Moreover, his articulation rests on foundational precepts grounded in the Abrahamic moral tradition and is informed by an esoteric spirit of Islam that has long been captured in Shī‘ī and Ṣūfī thought.This dissertation also discusses the ways in which the cosmopolitan ethic is manifested within the institutions of the Imāmate in Canada. Using the case study of three institutions: the Global Centre for Pluralism, the Ismā‘īlī Centre Toronto, and the Aga Khan Museum, I demonstrate how these sites implement and craft a spirit of cosmopolitanism within their infrastructure and programing while exhibiting elements that are rooted in history and tradition

Lab-on-a-chip device to quantify buffer capacity of blood

An accurate estimation of physiological buffer capacity and total titratable buffer concentration of blood can give a great deal of insight into the physiological stability of a patient and yet it remains an undervalued diagnostic marker. This thesis highlights the need for a lab-on-chip device to quantify buffer capacity of whole blood samples by estimating the total titratable buffer concentration. Buffer capacity is quantified by titrating the buffer to its end point using monoprotic acids. More sophisticated ways include electrolytic titration, i.e. producing a proton flux using electrodes in a controlled environment. This thesis looks at a novel approach to electrolytic (coulometric) titration by inhibiting the production of OH ions during electrolysis and titrating the sample due to the proton flux from the anode. By definition, is the amount of acid or base added to change the pH of 1 litre of buffer by 1 pH unit. The carbonic acid bicarbonate buffer system is the most important buffer that maintains the body’s pH within a stable range. To quantify this buffer’s total buffering concentration, it is important to know and indicate its titration end point which signifies the total exhaustion of all buffering constituents. Colorimetric indicators have been used to indicate this end point which can be quantified through cameras or spectrophotometric techniques. Using this novel coulometric titrator and the colorimetric end point detector, this thesis presents a portable lab-on-chip prototype to spectrophotometrically quantify total titratable buffer concentration. Clinically, this device could benefit patients with sickle cell disease, nephritic disease and those admitted in accident and emergency wards. This research work is aimed at presenting a proof-of-concept for a device that can titrate nano-litre samples and be able to detect the end point of a titration in a controlled way.Open Acces

The composition, geographical variation and antimicrobial activity of Mentha longifolia subspecies polyadena (Lamiaceae) leaf essential oils

Mentha longifolia subsp. polyadena was collected from seven localities in South Africa and from a single population in Botswana to study the essential oil composition and antimicrobial activity of this ethnomedicinal plant. The essential oils were obtained by hydrodistillation and analysed by gas chromatography coupled to mass spectroscopy (GC/MS) and a cluster analysis was performed on the essential oil dataset. From eight samples (representing eight natural populations), two major chemotypes were identified: (i) a menthofuran rich type (51.4% - 61.6%); and (ii) a cis-piperitone epoxide (14.7% – 35.7%) and piperitenone oxide (14.6% - 65.7%) rich type. The constituent analysis showed quantitative variation with higher amounts of oxygencontaining monoterpenes ranging from 56.5% to 89.6% whilst the sesquiterpene hydrocarbons ranged from 4.4% to 16.7%. The essential oil from the different localities mostly showed moderate to good antimicrobial activity against Staphylococcus aureus, Staphylococcus epidermidis, Bacillus cereus, Moraxella catarrhalis, Yersinia enterocolitica and Enterococcus faecalis. The oils were generally inactive against Escherichia coli and Salmonella typhimurium. Candida albicans and Cryptococcus neoformans indicated highest sensitivities for oil samples from Komukwane (3 mg/ml and 0.5 mg/ml respectively) and Prins Albert (0.5 mg/ml and 1.6 mg/ml respectively). The HPLC profiles of the methanol and chloroform (1:1) extracts were more conservative and less variable compared to the essential oils. Two major peaks corresponding to retention times of 22.39 min and 26.47 min were present in all eight samples. Most of the solvent extracts displayed moderate to good antimicrobial activity against Gram-positive pathogens, in particular against S. aureus, S. epidermidis and B. cereus with MIC values ranging from 0.5 mg/ml to 2 mg/ml in most cases. The extracts also demonstrated moderate to good activity against most of the Gram-negative pathogens, in particular against Y. eneterocolitica and M. catarrhalis, with MIC values ranging from 0.5 mg/ml to 2 mg/ml. These results may in part provide scientific evidence for the extensive use of Mentha longifolia in traditional healing

Doctor of Philosophy

dissertationChemical-looping combustion (CLC) is one of the candidate technologies that is currently being explored to reduce the energy penalty associated with capturing CO2 from coal-fired power plants. In CLC, the fuel is burnt in the presence of oxygen supplied by an oxygen carrier circulating between two reactors, instead of atmospheric air. This dissertation investigates the requisite process modeling aspects for CLC for solid carbonaceous fuels, in particular focusing on chemical-looping with oxygen uncoupling (CLOU). In CLOU, gaseous phase oxygen is released by the decomposition of a metal oxide (e.g. CuO) in which the solid fuel burns to form CO2 . This contrasts with CLC, where the solid fuel has to be gasified initially to form syngas which subsequently reacts with the circulating oxygen carrier to form CO2. As a first step, the significance of the Law of Additive Reaction Times in identifying the controlling regime (internal/external mass transfer or chemical reaction) for CLC systems was explored. Two reported experimental studies for copper oxidation reaction in air reactor were reanalyzed. The methodology developed was applied to analyze the CuO decomposition and Cu2O oxidation reaction for CLOU. A rate analysis of the reported bench-scale batch fluidized-bed CLOU experimental data was performed to determine the kinetics of the CuO decomposition, Cu2O oxidation, and petcoke oxidation reactions. The obtained kinetics were subsequently utilized in the development of a fluidized-bed model to evaluate the oxygen and carbon dioxide concentration trends, and the results were validated against independently obtained experimental data reported in literature. The kinetics obtained from the rate analysis of the CLOU reactions were employed in the development of a process model using ASPEN PLUS. Material and energy balance scenarios were developed for solid fuel combustion using a copper-based oxygen carrier for CLOU, and compared with CLC employing an iron-based oxygen carrier. The conceptual design principles will be employed in future investigations on a process development unit based on the CLOU process currently under construction at the University of Utah

Reconciliation of discrete and continuous versions of some dynamic inequalities synthesized on time scale calculus

summary:The aim of this paper is to synthesize discrete and continuous versions of some dynamic inequalities such as Radon's Inequality, Bergström's Inequality, Schlömilch's Inequality and Rogers-Hölder's Inequality on time scales in comprehensive form

Situasi Pneumonia di Wilayah Kerja Dinas Kesehatan Kabupaten Gowa Sulawesi Selatan Tahun 2017

Infeksi Pneumonia muncul karena adanya invasi mikroorganisme atau virus, bakteri atau jamur pada paru-paru.Umumnya pneumonia ditandai dengan batuk-batuk berdahak dengan sputum kehijauan atau kuning, demam tinggi dan menggigil serta nafas yang pendek. Tujuan penelitian ini adalah diperolehnya gambaran kasus pneumonia di wilayah kerja Dinas Kesehatan Kabupaten Gowa. Hasil penelitian ditemukan bahwa penemuan kasus pneumonia tertinggi pada Balita di wilayah Kabupaten Gowa adalah sebesar 57,7% terjadi pada Balita laki-laki. Sedangkan sebesar 42,3% ditemukan pada Balita perempuan. Berdasarkan hasil penelitian dapat diketahui bahwa penemuan kasus pneumonia tertinggi pada Balita di wilayah Kabupaten Gowa adalah sebesar 27,5% yang terdapat di Kecamatan Sombaopu. Untuk penemuan kasus terendah pada Balita di wilayah Kabupaten Gowa adalah sebesar 0,1% yang terdapat di Kecamatan Bontonompo Selatan. Ditemukan bahwa penemuan kasus pneumonia tertinggi pada Balita di wilayah Kabupaten Gowa adalah sebesar 28,3% yang terdapat di Puskesmas Sombaopu. Sedangkan penemuan kasus terendah pada Balita di wilayah Kabupaten Gowa adalah sebesar 0,1% yang terdapat di Puskesmas Bontonompo I Kesimpulan masih ditemukan kasus pneumonia dengan jumlah kasus dibawah angka nasional yaitu 2%

Concordance of dynamic fractional inequalities interconnected on time scales

In this work, we present an extension of dynamic reverse Minkowski’s inequality by using the time scale Riemann–Liouville type fractional integrals. By using the definitions of delta and nabla time scales Riemann–Liouville type fractional integral operators, we find other general dynamic fractional inequalities. Our findings unify and extend some continuous, discrete and quantum analogues.Publisher's Versio

Multi-Modality at Tourism Destination: An Overview of the Transportation Network at The UNESCO Heritage Site Melaka, Malaysia

Antecedents of a tourism destination’s sustainability and competitiveness rely on its transportation networks to facilitate the movement of traffic for locals and tourist alike. Multi-modality is vital to support the local economies, which garner its revenue from tourism activities. Modality plays a vital role to facilitate the mobility of tourists, inter destinations and within the destinations and relates to the accessibility aspects at a tourism destination. An observational study, paired with a comprehensive analysis of literature, is conducted to explore the gamut of the transportation networks in Melaka and its relation and contribution to the tourism industry. The investigation shows that the Melaka’s tourism industry is dependent on the transportation networks. Public transportations are found to be inadequate. Issues such as seasonal congestion and public transportation inadequacy need to be addressed immediately to ensure that smooth flow and dispersal of traffic, entering and exiting Melaka