1,640 research outputs found
Symmetric informationally complete positive operator valued measure and probability representation of quantum mechanics
Symmetric informationally complete positive operator valued measures
(SIC-POVMs) are studied within the framework of the probability representation
of quantum mechanics. A SIC-POVM is shown to be a special case of the
probability representation. The problem of SIC-POVM existence is formulated in
terms of symbols of operators associated with a star-product quantization
scheme. We show that SIC-POVMs (if they do exist) must obey general rules of
the star product, and, starting from this fact, we derive new relations on
SIC-projectors. The case of qubits is considered in detail, in particular, the
relation between the SIC probability representation and other probability
representations is established, the connection with mutually unbiased bases is
discussed, and comments to the Lie algebraic structure of SIC-POVMs are
presented.Comment: 22 pages, 1 figure, LaTeX, partially presented at the Workshop
"Nonlinearity and Coherence in Classical and Quantum Systems" held at the
University "Federico II" in Naples, Italy on December 4, 2009 in honor of
Prof. Margarita A. Man'ko in connection with her 70th birthday, minor
misprints are corrected in the second versio
MuSR method and tomographic probability representation of spin states
Muon spin rotation/relaxation/resonance (MuSR) technique for studying matter
structures is considered by means of a recently introduced probability
representation of quantum spin states. A relation between experimental MuSR
histograms and muon spin tomograms is established. Time evolution of muonium,
anomalous muonium, and a muonium-like system is studied in the tomographic
representation. Entanglement phenomenon of a bipartite muon-electron system is
investigated via tomographic analogues of Bell number and positive partial
transpose (PPT) criterion. Reconstruction of the muon-electron spin state as
well as the total spin tomography of composed system is discussed.Comment: 20 pages, 4 figures, LaTeX, submitted to Journal of Russian Laser
Researc
Geographically widespread invasive meningococcal disease caused by a ciprofloxacin resistant non-groupable strain of the ST-175 clonal complex.
INTRODUCTION: Invasive meningococcal disease (IMD) caused by non-serogroupable (NG) strains mainly affects immunocompromised individuals. Reduced susceptibility to penicillin in meningococci is increasing in Europe but ciprofloxacin resistance remains rare. In 2019, three travel-related meningococcal disease cases caused by a ciprofloxacin-resistant NG strain were identified in England, leading Germany to report four additional IMD cases (2016 to 2019). We describe these and newly identified cases and characterise the strain responsible. METHODS: Cases were identified as part of national surveillance and by analysing available genomes using PubMLST tools. RESULTS: Of the cases identified in England in 2019, two geographically distinct cases developed conjunctivitis after returning from Mecca (Kingdom of Saudi Arabia) and a third linked case presented with IMD. Of the four cases from Germany, three occurred in asylum seekers - two familial and a further geographically distinct case. Further IMD cases were identified in Italy (n = 2; 2017-2018), Sweden (n = 1; 2016) and England (n = 1; 2015). A single ST-175 clonal complex (cc175) strain with genosubtype P1.22-11,15-25 was responsible. Decreased susceptibility to penicillin was widespread with three ciprofloxacin resistant subclusters. Constituent isolates were potentially covered by subcapsular vaccines. CONCLUSION: This disease associated NG cc175 strain exhibits resistance to antibiotics commonly used to prevent IMD but is potentially covered by subcapsular (meningococcal B) vaccines
The Late-time Afterglow Evolution of Long Gamma-Ray Bursts GRB 160625B and GRB 160509A
We present post-jet-break Hubble Space Telescope, Very Large Array, and Chandra observations of the afterglow of the long γ-ray bursts GRB 160625B (between 69 and 209 days) and GRB 160509A (between 35 and 80 days). We calculate the post-jet-break decline rates of the light curves and find the afterglow of GRB 160625B is inconsistent with a simple t −3/4 steepening over the break, expected from the geometric effect of the jet edge entering our line of sight. However, the favored optical post-break decline () is also inconsistent with the f ν ∝ t −p decline (where p ≈ 2.3 from the pre-break light curve), which is expected from exponential lateral expansion of the jet; perhaps suggesting lateral expansion that only affects a fraction of the jet. The post-break decline of GRB 160509A is consistent with both the t −3/4 steepening and with f ν ∝ t −p . We also use boxfit to fit afterglow models to both light curves and find both to be energetically consistent with a millisecond magnetar central engine, but the magnetar parameters need to be extreme (i.e., E ~ 3 × 1052 erg). Finally, the late-time radio light curves of both afterglows are not reproduced well by boxfit and are inconsistent with predictions from the standard jet model; instead, both are well represented by a single power-law decline (roughly f ν ∝ t −1) with no breaks. This requires a highly chromatic jet break () and possibly a two-component jet for both bursts
A viscoelastic deadly fluid in carnivorous pitcher plants
Background : The carnivorous plants of the genus Nepenthes, widely
distributed in the Asian tropics, rely mostly on nutrients derived from
arthropods trapped in their pitcher-shaped leaves and digested by their
enzymatic fluid. The genus exhibits a great diversity of prey and pitcher forms
and its mechanism of trapping has long intrigued scientists. The slippery inner
surfaces of the pitchers, which can be waxy or highly wettable, have so far
been considered as the key trapping devices. However, the occurrence of species
lacking such epidermal specializations but still effective at trapping insects
suggests the possible implication of other mechanisms. Methodology/Principal
Findings : Using a combination of insect bioassays, high-speed video and
rheological measurements, we show that the digestive fluid of Nepenthes
rafflesiana is highly viscoelastic and that this physical property is crucial
for the retention of insects in its traps. Trapping efficiency is shown to
remain strong even when the fluid is highly diluted by water, as long as the
elastic relaxation time of the fluid is higher than the typical time scale of
insect movements. Conclusions/Significance : This finding challenges the common
classification of Nepenthes pitchers as simple passive traps and is of great
adaptive significance for these tropical plants, which are often submitted to
high rainfalls and variations in fluid concentration. The viscoelastic trap
constitutes a cryptic but potentially widespread adaptation of Nepenthes
species and could be a homologous trait shared through common ancestry with the
sundew (Drosera) flypaper plants. Such large production of a highly
viscoelastic biopolymer fluid in permanent pools is nevertheless unique in the
plant kingdom and suggests novel applications for pest control
Qubit portrait of the photon-number tomogram and separability of two-mode light states
In view of the photon-number tomograms of two-mode light states, using the
qubit-portrait method for studying the probability distributions with infinite
outputs, the separability and entanglement detection of the states are studied.
Examples of entangled Gaussian state and Schr\"{o}dinger cat state are
discussed.Comment: 20 pages, 6 figures, TeX file, to appear in Journal of Russian Laser
Researc
Resilin and chitinous cuticle form a composite structure for energy storage in jumping by froghopper insects
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are.Abstract Background Many insects jump by storing and releasing energy in elastic structures within their bodies. This allows them to release large amounts of energy in a very short time to jump at very high speeds. The fastest of the insect jumpers, the froghopper, uses a catapult-like elastic mechanism to achieve their jumping prowess in which energy, generated by the slow contraction of muscles, is released suddenly to power rapid and synchronous movements of the hind legs. How is this energy stored? Results The hind coxae of the froghopper are linked to the hinges of the ipsilateral hind wings by pleural arches, complex bow-shaped internal skeletal structures. They are built of chitinous cuticle and the rubber-like protein, resilin, which fluoresces bright blue when illuminated with ultra-violet light. The ventral and posterior end of this fluorescent region forms the thoracic part of the pivot with a hind coxa. No other structures in the thorax or hind legs show this blue fluorescence and it is not found in larvae which do not jump. Stimulating one trochanteral depressor muscle in a pattern that simulates its normal action, results in a distortion and forward movement of the posterior part of a pleural arch by 40 μm, but in natural jumping, the movement is at least 100 μm. Conclusion Calculations showed that the resilin itself could only store 1% to 2% of the energy required for jumping. The stiffer cuticular parts of the pleural arches could, however, easily meet all the energy storage needs. The composite structure therefore, combines the stiffness of the chitinous cuticle with the elasticity of resilin. Muscle contractions bend the chitinous cuticle with little deformation and therefore, store the energy needed for jumping, while the resilin rapidly returns its stored energy and thus restores the body to its original shape after a jump and allows repeated jumping
Evaluation of the current knowledge limitations in breast cancer research: a gap analysis
BACKGROUND
A gap analysis was conducted to determine which areas of breast cancer research, if targeted by researchers and funding bodies, could produce the greatest impact on patients.
METHODS
Fifty-six Breast Cancer Campaign grant holders and prominent UK breast cancer researchers participated in a gap analysis of current breast cancer research. Before, during and following the meeting, groups in seven key research areas participated in cycles of presentation, literature review and discussion. Summary papers were prepared by each group and collated into this position paper highlighting the research gaps, with recommendations for action.
RESULTS
Gaps were identified in all seven themes. General barriers to progress were lack of financial and practical resources, and poor collaboration between disciplines. Critical gaps in each theme included: (1) genetics (knowledge of genetic changes, their effects and interactions); (2) initiation of breast cancer (how developmental signalling pathways cause ductal elongation and branching at the cellular level and influence stem cell dynamics, and how their disruption initiates tumour formation); (3) progression of breast cancer (deciphering the intracellular and extracellular regulators of early progression, tumour growth, angiogenesis and metastasis); (4) therapies and targets (understanding who develops advanced disease); (5) disease markers (incorporating intelligent trial design into all studies to ensure new treatments are tested in patient groups stratified using biomarkers); (6) prevention (strategies to prevent oestrogen-receptor negative tumours and the long-term effects of chemoprevention for oestrogen-receptor positive tumours); (7) psychosocial aspects of cancer (the use of appropriate psychosocial interventions, and the personal impact of all stages of the disease among patients from a range of ethnic and demographic backgrounds).
CONCLUSION
Through recommendations to address these gaps with future research, the long-term benefits to patients will include: better estimation of risk in families with breast cancer and strategies to reduce risk; better prediction of drug response and patient prognosis; improved tailoring of treatments to patient subgroups and development of new therapeutic approaches; earlier initiation of treatment; more effective use of resources for screening populations; and an enhanced experience for people with or at risk of breast cancer and their families. The challenge to funding bodies and researchers in all disciplines is to focus on these gaps and to drive advances in knowledge into improvements in patient care
A snapshot of the Mamu-B genes and their allelic repertoire in rhesus macaques of Chinese origin
The major histocompatibility complex class I gene repertoire was investigated in a large panel of rhesus macaques of Chinese origin. As observed in Indian animals, subjects of Chinese derivation display Mamu-B gene copy number variation, and the sum of expressed genes varies among haplotypes. In addition, these genes display differential transcription levels. The majority of the Mamu-B alleles discovered during this investigation appear to be unique for the population studied. Only one particular Mamu-B haplotype is shared between Indian and Chinese animals, and it must have been present in the progenitor stock. Hence, the data highlight the fact that most allelic polymorphism, and most of the Mamu-B haplotypes themselves, are of relatively recent origin and were most likely generated after the separation of the Indian and Chinese rhesus macaque populations
Search for Charged Higgs Bosons in e+e- Collisions at \sqrt{s} = 189 GeV
A search for pair-produced charged Higgs bosons is performed with the L3
detector at LEP using data collected at a centre-of-mass energy of 188.6 GeV,
corresponding to an integrated luminosity of 176.4 pb^-1. Higgs decays into a
charm and a strange quark or into a tau lepton and its associated neutrino are
considered. The observed events are consistent with the expectations from
Standard Model background processes. A lower limit of 65.5 GeV on the charged
Higgs mass is derived at 95 % confidence level, independent of the decay
branching ratio Br(H^{+/-} -> tau nu)
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