3,034 research outputs found

    A Bootstrap Stationarity Test for Predictive Regression Invalidity

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    In order for predictive regression tests to deliver asymptotically valid inference, account has to be taken of the degree of persistence of the predictors under test. There is also a maintained assumption that any predictability in the variable of interest is purely attributable to the predictors under test. Violation of this assumption by the omission of relevant persistent predictors renders the predictive regression invalid, and potentially also spurious, as both the finite sample and asymptotic size of the predictability tests can be significantly in ated. In response we propose a predictive regression invalidity test based on a stationarity testing approach. To allow for an unknown degree of persistence in the putative predictors, and for heteroskedasticity in the data, we implement our proposed test using a fixed regressor wild bootstrap procedure. We demonstrate the asymptotic validity of the proposed bootstrap test by proving that the limit distribution of the bootstrap statistic, conditional on the data, is the same as the limit null distribution of the statistic computed on the original data, conditional on the predictor. This corrects a long-standing error in the bootstrap literature whereby it is incorrectly argued that for strongly persistent regressors and test statistics akin to ours the validity of the fixed regressor bootstrap obtains through equivalence to an unconditional limit distribution. Our bootstrap results are therefore of interest in their own right and are likely to have applications beyond the present context. An illustration is given by re-examining the results relating to U.S. stock returns data in Campbell and Yogo (2006)

    Methanethiol, dimethyl sulfide and acetone over biologically productive waters in the southwest Pacific Ocean

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    Atmospheric methanethiol (MeSHa), dimethyl sulïŹde (DMSa) and acetone (acetonea) were measured over biologically productive frontal waters in the remote southwest PaciïŹc Ocean in summertime 2012 during the Surface Ocean Aerosol Production (SOAP) voyage. MeSHa mixing ratios varied from below the detection limit (<10ppt) up to 65ppt and were 3%–36% of parallel DMSa mixing ratios. MeSHa and DMSa were correlated over the voyage(R2=0.3,slope=0.07)with a stronger correlation over a coccolithophore-dominated phytoplankton bloom (R2= 0.5, slope 0.13). The diurnal cycle for MeSHa shows similar behaviour to DMSa with mixing ratios varying by a factor of ∌2 according to time of day with the minimum levels of both MeSHa and DMSa occurring at around 16:00LT (local time, all times in this paper are in local time). A positive ïŹ‚ux of MeSH out of the ocean was calculated for three different nights and ranged from 3.5 to 5.8”molm−2 d−1, corresponding to 14%–24% of the DMS ïŹ‚ux (MeSH/(MeSH+DMS)). Spearman rank correlations with ocean biogeochemical parameters showed a moderate to-strong positive, highly signiïŹcant relationship between both MeSHa and DMSa with seawater DMS (DMSsw) and a moderate correlation with total dimethylsulfoniopropionate (total DMSP). A positive correlation of acetonea with water temperature and negative correlation with nutrient concentrations are consistent with reports of acetone production in warmer subtropical waters. Positive correlations of acetonea with cryptophyte and eukaryotic phytoplankton numbers, and high-molecular-weight sugars and chromophoric dissolved organic matter (CDOM), suggest an organic source. This work points to a signiïŹcant ocean source of MeSH, highlighting the need for further studies into the distribution and fate of MeSH, and it suggests links between atmospheric acetone levels and biogeochemistry over the midlatitude ocean. In addition, an intercalibration of DMSa at ambient levels using three independently calibrated instruments showed ∌15%–25% higher mixing ratios from an atmospheric pressure ionisation chemical ionisation mass spectrometer (mesoCIMS) compared to a gas chromatograph with a sulfurchemiluminescencedetector(GC-SCD)and proton transfer reaction mass spectrometer (PTR-MS). Some differences were attributed to the DMSa gradient above the sea surface and differing approaches of integrated versus discrete measurements. Remaining discrepancies were likely due to different calibrationscales,suggesting that further investigation of the stability and/or absolute calibration of DMSstandards used at sea is warranted

    Constructing a logistics space: perspectives form the Gulf Cooperation Council

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    Development plans across the Gulf Cooperation Council emphasise logistical infrastructure as a driver of economic diversification. Investments in maritime ports, roads, rail, airports and logistics cities are transforming the economic geography of the region. This study aims to make visible this neglected aspect of the physical transformation of the Gulf Cooperation Council with a focus on the understudied maritime container ports in Oman and Qatar. Shifting the analysis to emergent maritime logistical infrastructure at a regional level gives insight into the uneven developments within the Gulf Cooperation Council’s integration project. Three key features emerge: (a) a large degree of duplication in maritime port infrastructure across Gulf Cooperation Council states; (b) a regional hierarchy among Gulf Cooperation Council states that are resource rich and those dependent on public–private partnerships and (c) increasing competition among internationally dominant port operators looking to gain access to the Gulf Cooperation Council maritime port market. These features both reflect and reinforce competitive tensions within the regional integration project

    The role of rewilding in mitigating hydrological extremes: State of the evidence

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    Landscape rewilding has the potential to help mitigate hydrological extremes by allowing natural processes to function. Our systematic review assessed the evidence base for rewilding-driven mitigation of high and low flows. The review uncovers a lack of research directly addressing rewilding, but highlights research in analogue contexts which can, with caution, indicate the nature of change. There is a lack of before-after studies that enable deeper examination of temporal trajectories and legacy effects, and a lack of research on the scrub and shrubland habitats common in rewilding projects. Over twice as much evidence is available for high flows compared to low flows, and fewer than one third of studies address high and low flows simultaneously, limiting our understanding of co-benefits and contrasting effects. Flow magnitude variables are better represented within the literature than flow timing variables, and there is greater emphasis on modeling for high flows, and on direct measurement for low flows. Most high flow studies report a mitigating effect, but with variability in the magnitude of effect, and some exceptions. The nature of change for low flows is more complex and suggests a higher potential for increased low flow risks associated with certain trajectories but is based on a very narrow evidence base. We recommend that future research aims to: capture effects on both high and low flow extremes for a given type of change; analyze both magnitude and timing characteristics of flow extremes; and examine temporal trajectories (before and after data) ideally using a full before-after-control-impact design. This article is categorized under: Human Water > Value of Water Science of Water > Hydrological Processes Science of Water > Water Extremes Water and Life > Conservation, Management, and Awareness

    First Fruits of the Spitzer Space Telescope: Galactic and Solar System Studies

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    This article provides a brief overview of the Spitzer Space Telescope and discusses its initial scientific results on galactic and solar system science.Comment: Review article to appear in slightly different format in Vol.44 of Annual Reviews of Astronomy and Astrophysics, 200

    National Mesothelioma Virtual Bank: A standard based biospecimen and clinical data resource to enhance translational research

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    Background: Advances in translational research have led to the need for well characterized biospecimens for research. The National Mesothelioma Virtual Bank is an initiative which collects annotated datasets relevant to human mesothelioma to develop an enterprising biospecimen resource to fulfill researchers' need. Methods: The National Mesothelioma Virtual Bank architecture is based on three major components: (a) common data elements (based on College of American Pathologists protocol and National North American Association of Central Cancer Registries standards), (b) clinical and epidemiologic data annotation, and (c) data query tools. These tools work interoperably to standardize the entire process of annotation. The National Mesothelioma Virtual Bank tool is based upon the caTISSUE Clinical Annotation Engine, developed by the University of Pittsburgh in cooperation with the Cancer Biomedical Informatics Gridℱ (caBIGℱ, see http://cabig.nci.nih.gov). This application provides a web-based system for annotating, importing and searching mesothelioma cases. The underlying information model is constructed utilizing Unified Modeling Language class diagrams, hierarchical relationships and Enterprise Architect software. Result: The database provides researchers real-time access to richly annotated specimens and integral information related to mesothelioma. The data disclosed is tightly regulated depending upon users' authorization and depending on the participating institute that is amenable to the local Institutional Review Board and regulation committee reviews. Conclusion: The National Mesothelioma Virtual Bank currently has over 600 annotated cases available for researchers that include paraffin embedded tissues, tissue microarrays, serum and genomic DNA. The National Mesothelioma Virtual Bank is a virtual biospecimen registry with robust translational biomedical informatics support to facilitate basic science, clinical, and translational research. Furthermore, it protects patient privacy by disclosing only de-identified datasets to assure that biospecimens can be made accessible to researchers. © 2008 Amin et al; licensee BioMed Central Ltd

    Boron-Doped Diamond Dual-Plate Deep-Microtrench Device for Generator-Collector Sulfide Sensing

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    This is the author accepted manuscript. The final version is available from Wiley via the DOI in this record.A BDD-BDD dual-plate microtrench electrode with 6ÎŒm inter-electrode spacing is investigated using generator-collector electrochemistry and shown to give microtrench depth-dependent sulfide detection down to the ÎŒM levels. The effect of the microtrench depth is compared for a "shallow" 44 ÎŒm and a "deep" 180ÎŒm microtrench and linked to the reduction of oxygen to hydrogen peroxide which interferes with sulfide redox cycling. With a deeper microtrench and a fixed collector potential at -1.4V vs. SCE, two distinct redox cycling potential domains are observed at 0.0V vs. SCE (2-electron) and at 1.1V vs. SCE (6-electron).F. M. and A. J. G. thank EPSRC for financial support (EP/I028706/1)

    A life cycle stakeholder management framework for enhanced collaboration between stakeholders with competing interests

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    This is a postprint version of the Book Chapter. Information regarding the official publication is available from the link below - Copyright @ 2011 SpringerImplementation of a Life Cycle Sustainability Management (LCSM) strategy can involve significant challenges because of competing or conflicting objectives between stakeholders. These differences may, if not identified and managed, hinder successful adoption of sustainability initiatives. This article proposes a conceptual framework for stakeholder management in a LCSM context. The framework identifies the key sustainability stakeholder groups and suggests strategic ambiguity as a management tool to harness dysfunctional conflict into constructive collaboration. The framework is of practical value as it can be used as a guideline by managers who wish to improve collaboration with stakeholders along the supply chain. The article also fills a gap in the academic literature where there is only limited research on sustainability stakeholder management through strategic ambiguity

    The contribution of diet and genotype to iron status in women:a classical twin study

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    This is the first published report examining the combined effect of diet and genotype on body iron content using a classical twin study design. The aim of this study was to determine the relative contribution of genetic and environmental factors in determining iron status. The population was comprised of 200 BMI- and age-matched pairs of MZ and DZ healthy twins, characterised for habitual diet and 15 iron-related candidate genetic markers. Variance components analysis demonstrated that the heritability of serum ferritin (SF) and soluble transferrin receptor was 44% and 54% respectively. Measured single nucleotide polymorphisms explained 5% and selected dietary factors 6% of the variance in iron status; there was a negative association between calcium intake and body iron (p = 0.02) and SF (p = 0.04)
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