On the phase structure and thermodynamics of QCD

We discuss the phase structure and thermodynamics of QCD by means of dynamical chiral effective models. Quark and meson fluctuations are included via the functional renormalization group. We study the influence of confinement in addition to the impact of fluctuations by comparing the results of the chiral models to their Polyakov-loop extended versions. Furthermore, we discuss the mass sensitivity of the phase structure and thermodynamics and find interesting modifications close to the chiral limit.Comment: 13 pages, 11 figures; Appendix added; published versio

A search for millimetric emission from Gamma Ray Bursts

We have used the 2- year Differential Microwave Radiometer data from the COsmic Background Explorer (COBE) satellite to systematically search for millimetric (31 - 90 GHz) emission from the Gamma Ray Bursts (GRBs) in the Burst And Transient Source Experiment (BATSE) GRB 3B catalog. The large beamsize of the COBE instrument (7 degs FWHM) allows for an efficient search of the large GRB positional error boxes, although it also means that fluxes from (point source) GRB objects will be somewhat diluted. A likelihood analysis has been used to look for a change in the level of millimetric emission from the locations of 81 GRB events during the first two years (1990 & 1991) of the COBE mission. The likelihood analysis determined that we did not find any significant millimetric signal before or after the occurance of the GRB. We find 95% confidence level upper limits of 175, 192 and 645 Jy or, in terms of fluxes, of 9.6, 16.3 and 54.8 10^{-13} erg/cm^2/s, respectively at 31, 53 and 90 GHz. We also look separately at different classes of GRBs, including a study of the top ten (in peak flux) GRBs, the "short burst" and "long burst" subsets, finding similar upper limits. While these limits may be somewhat higher than one would like, we estimate that using this technique with future planned missions could push these limits down to \sim 1 mJy.Comment: 21 pages, 5 figures, to be published in The Astrophysical Journa

Vacuum fluctuations and the thermodynamics of chiral models

We consider the thermodynamics of chiral models in the mean-field approximation and discuss the relevance of the (frequently omitted) fermion vacuum loop. Within the chiral quark-meson model and its Polyakov loop extended version, we show that the fermion vacuum fluctuations can change the order of the phase transition in the chiral limit and strongly influence physical observables. We compute the temperature-dependent effective potential and baryon number susceptibilities in these models, with and without the vacuum term, and explore the cutoff and the pion mass dependence of the susceptibilities. Finally, in the renormalized model the divergent vacuum contribution is removed using the dimensional regularization.Comment: 9 pages, 5 figure

Quantification of Plasma and Urine Thymidine and 2'-Deoxyuridine by LC-MS/MS for the Pharmacodynamic Evaluation of Erythrocyte Encapsulated Thymidine Phosphorylase in Patients with Mitochondrial Neurogastrointestinal Encephalomyopathy.

Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an ultra-rare disorder caused by mutations in TYMP, leading to a deficiency in thymidine phosphorylase and a subsequent systemic accumulation of thymidine and 2'-deoxyuridine. Erythrocyte-encapsulated thymidine phosphorylase (EE-TP) is under clinical development as an enzyme replacement therapy for MNGIE. Bioanalytical methods were developed according to regulatory guidelines for the quantification of thymidine and 2'-deoxyuridine in plasma and urine using liquid chromatography-tandem mass spectrometry (LC-MS/MS) for supporting the pharmacodynamic evaluation of EE-TP. Samples were deproteinized with 5% perchloric acid (v/v) and the supernatants analyzed using a Hypercarb column (30 × 2.1 mm, 3 µm), with mobile phases of 0.1% formic acid in methanol and 0.1% formic acid in deionized water. Detection was conducted using an ion-spray interface running in positive mode. Isotopically labelled thymidine and 2'-deoxyuridine were used as internal standards. Calibration curves for both metabolites showed linearity (r > 0.99) in the concentration ranges of 10-10,000 ng/mL for plasma, and 1-50 µg/mL for urine, with method analytical performances within the acceptable criteria for quality control samples. The plasma method was successfully applied to the diagnosis of two patients with MNGIE and the quantification of plasma metabolites in three patients treated with EE-TP

Individual Values and SME Environmental Engagement

We study the values on which managers of small and medium-sized enterprises draw when constructing their personal and organizational-level engagement with environmental issues, particularly climate change. Values play an important mediating role in business environmental engagement but relatively little research has been conducted on individual values in smaller organizations. Using the Schwartz Value System (SVS) as a framework for a qualitative analysis, we identify four ‘ideal-types’ of SME managers and provide rich descriptions of the ways in which values shape their constructions of environmental engagement. In contrast to previous research, which is framed around a binary divide between self-enhancing and self-transcending values, our typology distinguishes between individuals drawing primarily on Power or on Achievement values, and indicates how a combination of Achievement and Benevolence values is particularly significant in shaping environmental engagement. This demonstrates the theoretical usefulness of focusing on a complete range of values. Implications for policy and practice are discussed

From X-ray dips to eclipse: Witnessing disk reformation in the recurrent nova USco

The 10th recorded outburst of the recurrent eclipsing nova USco was observed simultaneously in X-ray, UV, and optical by XMM-Newton on days 22.9 and 34.9 after outburst. Two full passages of the companion in front of the nova ejecta were observed, witnessing the reformation of the accretion disk. On day 22.9, we observed smooth eclipses in UV and optical but deep dips in the X-ray light curve which disappeared by day 34.9, then yielding clean eclipses in all bands. X-ray dips can be caused by clumpy absorbing material that intersects the line of sight while moving along highly elliptical trajectories. Cold material from the companion could explain the absence of dips in UV and optical light. The disappearance of X-ray dips before day 34.9 implies significant progress in the formation of the disk. The X-ray spectra contain photospheric continuum emission plus strong emission lines, but no clear absorption lines. Both continuum and emission lines in the X-ray spectra indicate a temperature increase from day 22.9 to day 34.9. We find clear evidence in the spectra and light curves for Thompson scattering of the photospheric emission from the white dwarf. Photospheric absorption lines can be smeared out during scattering in a plasma of fast electrons. We also find spectral signatures of resonant line scattering that lead to the observation of the strong emission lines. Their dominance could be a general phenomenon in high-inclination systems such as Cal87.Comment: Submitted to ApJ. 16 pages, 16 figure

Mapping the phase diagram of strongly interacting matter

We employ a conformal mapping to explore the thermodynamics of strongly interacting matter at finite values of the baryon chemical potential $\mu$. This method allows us to identify the singularity corresponding to the critical point of a second-order phase transition at finite $\mu$, given information only at $\mu=0$. The scheme is potentially useful for computing thermodynamic properties of strongly interacting hot and dense matter in lattice gauge theory. The technique is illustrated by an application to a chiral effective model.Comment: 5 pages, 3 figures; published versio