The impact of loads on standard diameter, small diameter and mini implants: A comparative laboratory study

Objectives: While caution in the use of small-diameter (≤3.5 mm) implants has been advocated in view of an increased risk of fatigue fracture under clinical loading conditions, a variety of implant designs with diameters <3 mm are currently offered in the market for reconstructions including fixed restorations. There is an absence of reported laboratory studies and randomized-controlled clinical trials to demonstrate clinical efficacy for implant designs with small diameters. This laboratory study aimed to provide comparative data on the mechanical performance of a number of narrow commercially marketed implants. Materials and methods: Implants of varying designs were investigated under a standardized test set-up similar to that recommended for standardized ISO laboratory testing. Implant assemblies were mounted in acrylic blocks supporting laboratory cast crowns and subjected to 30° off-axis loading on an LRX Tensometer. Continuous output data were collected using Nexygen software. Results: Load/displacement curves demonstrated good grouping of samples for each design with elastic deformation up to a point of failure approximating the maximum load value for each sample. The maximum loads for Straumann (control) implants were 989 N (±107 N) for the 4.1 mm RN design, and 619 N (±50 N) for the 3.3 mm RN implant (an implant known to have a risk of fracture in clinical use). Values for mini implants were recorded as 261 N (±31 N) for the HiTec 2.4 mm implant, 237 N (±37 N) for the Osteocare 2.8 mm mini and 147 N (±25 N) for the Osteocare mini design. Other implant designs were also tested. Conclusions: The diameters of the commercially available implants tested demonstrated a major impact on their ability to withstand load, with those below 3 mm diameter yielding results significantly below a value representing a risk of fracture in clinical practice. The results therefore advocate caution when considering the applicability of implants ≤3 mm diameter. Standardized fatigue testing is recommended for all commercially available implants

Signature of Randall-Sundrum Quantum Gravity model in γγ\gamma\gamma scattering in the TeV range

We examine the implications of the Randall-Sundrum gravity models on $\gamma\gamma$ scattering in the TeV range.Comment: 7 pages, 4 figure

CP violation in the decay mode B→πγγB\to \pi \gamma \gamma

Within the framework of Standard Model, the exclusive decay mode $B\to \pi \gamma \gamma$ is studied. Although the usual short distance contribution is small compared to the similar $B\to K\gamma\gamma$ mode, the process offers the possibility of studying the CP violation, a feature absent in the $B \to K$ counterpart.Comment: 11 page latex file including 2 ps figures. Typos corrected, minor changes. To appear in PR

Gravitational Collapse of Cylindrical Shells Made of Counter-Rotating Dust Particles

The general formulas of a non-rotating dynamic thin shell that connects two arbitrary cylindrical regions are given using Israel's method. As an application of them, the dynamics of a thin shell made of counter-rotating dust particles, which emits both gravitational waves and massless particles when it is expanding or collapsing, is studied. It is found that when the models represent a collapsing shell, in some cases the angular momentum of the dust particles is strong enough to halt the collapse, so that a spacetime singularity is prevented from forming, while in other cases it is not, and a line-like spacetime singularity is finally formed on the symmetry axis.Comment: To appear in Phys. Rev.

The thyroid gland and its variations: a cadaveric study

The size and shape of the thyroid gland is subject to much variation, as stated by Wood Jones. Literature is replete with a large number of variations of the gland. By utilizing various techniques like gross dissection, histology, developmental anatomy, and recently thyroid scans and scintigraphy, some common and certain rare anomalies of the thyroid with their possible developmental bases are described in the literature. An attempt has been made to study the thyroid glands in 90 male cadavers available in our department, with ages ranging from 60 to 75 years with mean height of 5&#8217;4&#8221;. The parameters that were observed included the length and width of lobes, presence or absence of pyramidal lobe, levator glandulae thyroideae, and isthmus with its relation to the tracheal rings. The average length of the right lobe was 4.32 cm, and the left lobe was 4.22 cm. The thickness of the right lobe was 1.13 cm, and the left lobe was 1.18 cm. Pyramidal lobe was present in 34 (37.77%) cases, frequently arising from the left lobe, while the levator glandulae thyroideae was present in 27 (30%) instances, mostly attached superiorly to the body of the hyoid bone. The isthmus was absent in 15 (16.66%) cases; its relation with the tracheal rings greatly varied from the cricoid cartilage to the fourth tracheal ring. Knowledge of variations of the thyroid assumes significance as this has relevance in the resection of thyroid, tumours, and tracheostomy. Folia Morphol 2010; 69, 1: 47&#8211;5

Role of Continuous Glucose Monitoring in Clinical Trials: Recommendations on Reporting.

Thanks to significant improvements in the precision, accuracy, and usability of continuous glucose monitoring (CGM), its relevance in both ambulatory diabetes care and clinical research is increasing. In this study, we address the latter perspective and derive provisional reporting recommendations. CGM systems have been available since around the year 2000 and used primarily in people with type 1 diabetes. In contrast to self-measured glucose, CGM can provide continuous real-time measurement of glucose levels, alerts for hypoglycemia and hyperglycemia, and a detailed assessment of glycemic variability. Through a broad spectrum of derived glucose data, CGM should be a useful tool for clinical evaluation of new glucose-lowering medications and strategies. It is the only technology that can measure hyperglycemic and hypoglycemic exposure in ambulatory care, or provide data for comprehensive assessment of glucose variability. Other advantages of current CGM systems include the opportunity for improved self-management of glycemic control, with particular relevance to those at higher risk of or from hypoglycemia. We therefore summarize the current status and limitations of CGM from the perspective of clinical trials and derive suggested recommendations for how these should facilitate optimal CGM use and reporting of data in clinical research

Lepton polarization correlations in B→K∗τ−τ+B \to K^* \tau^- \tau^+

In this work we will study the polarizations of both leptons ($\tau$) in the decay channel $B\to K^* \tau^- \tau^+$. In the case of the dileptonic inclusive decay $B\to K^* \ell^- \ell^+$, where apart from the polarization asymmetries of single lepton $\ell$, one can also observe the polarization asymmetries of both leptons simultaneously. If this sort of measurement is possible then we can have, apart from decay rate, FB asymmetry and the six single lepton polarization asymmetries (three each for $\ell^-$ and $\ell^+$), nine more double polarization asymmetries. This will give us a very useful tool in more strict testing of SM and the physics beyond. We discuss the double polarization asymmetries of $\tau$ leptons in the decay mode $B\to K^* \tau^- \tau^+$ within the SM and the Minimal Supersymmetric extensions of it.Comment: 21 pages, 21 figures; version to match paper to appear in PR