The use of flour from germinated buckwheat in bread recipes

The results of the study of technological properties, chemical composition of buckwheat varieties of the Republic of Bashkortostan, as well as the effect of flour from sprouted buckwheat grain on the quality of wheat bread are presented. According to the nutritional value, in order to obtain buckwheat flour in order to include it in the bread recipe, the Inzer buckwheat variety was selected. The parameters of soaking and germination of buckwheat grain of this variety are optimized and it is shown that due to germination, the physico-chemical parameters of flour and its antioxidant activity are improved. Thus, the expediency of introducing flour from sprouted buckwheat grain into the recipe of wheat bread is proved. The optimal content of flour from sprouted buckwheat grain in the composition of a composite mixture with wheat flour of grade I, which amounted to 10%, providing an improvement in the organoleptic and physico-chemical parameters of bread, was established

ОБОСНОВАНИЕ ПРИМЕНЕНИЯ ЛЕЧЕБНЫХ ФАКТОРОВ ВНУТРЕННЕЙ СРЕДЫ СОВРЕМЕННЫХ УСТРОЙСТВ ИЗ ПРИРОДНОГО МИНЕРАЛА СИЛЬВИНИТА В СТОМАТОЛОГИИ

Background: One of the methods of comprehensive therapeutic effects on the human body is sylvinite therapy which has not been used in the treatment of inflammatory periodontal diseases at young age. Aims: Hygienic and clinical evaluation of the possible application of therapeutic factors of sylvinite devices in dentistry.Materials and methods: We conducted hygienic study of the basic physical factors of the internal environment of modern sylvinite structures (radiation background, aeroionization and aerosol environment, climate). The percentage of sylvine and halite in the sylvinite minerals was determined using color image analysis of the salt screen. The microbiological studies of the impact of the mineral sylvinite on the growth parameters of bacterial culture were performed. We examined 79 patients aged 20−25 years diagnosed with chronic generalized catarrhal gingivitis, 36 persons underwent treatment course in the salt structure. The evaluation of the dental status and the periodontal status was conducted using hygienic and periodontal indices. The duration of study was 4 years.Results: Аll participants who entered the study completed it. In the experimental sylvinite room formed food-grade, biodegradable internal environment (background radiation ― 0,18±0,0027 µsv/h; LOA ― 802,33±62,69 ion/cm3; RO ― 509,33±37,17 ion/cm3; stable microclimate). We detected evidence of an inhibitory effect of the combination on Staphylococcus aureus. The use of a comprehensive dental program has improved the condition of periodontal tissues and careeradvantage tooth enamel (PMA and SBI fell of 80.8% and 75.5%; the reduction of the CPU ― 67.7%; fuel and energy resources increased by 37%). Conclusions: The inclusion of sylvinite therapy in the complex treatment of patients with chronic generalized catarrhal gingivitis had a marked positive impact on the state of periodontal tissues and local immunity of the oral cavity.Обоснование. Одним из способов комплексного лечебного воздействия на организм человека является сильвинитотерапия, которая до настоящего времени не использовалась в терапии воспалительных заболеваний пародонта у лиц молодого возраста.Цель исследования: гигиеническая и клиническая оценка возможности применения лечебных факторов сильвинитовых устройств в стоматологии.Методы. Осуществляли гигиенические исследования основных физических факторов внутренней среды современных сооружений из калийных солей (радиационный фон, аэроионизационная и аэрозольная среды, микроклимат). Определяли содержание в сильвините минералов сильвина и галита с помощью разработанной нами компьютерной программы. Выполняли микробиологические исследования воздействия минерала сильвинита на ростовые показатели бактериальной культуры. Проводили рандомизированное проспективное исследование с участием 79 пациентов в возрасте 20−25 лет с диагнозом хронического генерализованного катарального гингивита, из них 36 человек проходили курс лечения в соляном сооружении. Оценивали стоматологический статус и состояние пародонта с использованием гигиенических и пародонтологических индексов. Продолжительность исследования составила 4 года.Результаты. Все участники, вступившие в исследование, завершили его. В экспериментальном сильвинитовом помещении формируется биопозитивная внутренняя среда (радиационный фон 0,18±0,0027 мкЗв/ч; содержание легких отрицательных аэроионов ― 802,33±62,69 ион/см3, легких положительных аэроионов ― 509,33±37,17 ион/см3; стабильный микроклимат). Доказано наличие ингибирующего влияния сильвинита на Staphylococcus aureus. Применение комплексной стоматологической программы способствовало улучшению состояния тканей пародонта и повышению кариесрезистентности эмали зубов: индексы гингивита и кровоточивости десневой борозды снизились на 80,8 и 75,5% соответственно; редукция уровня интенсивности кариеса (по индексу КПУ) составила 67,7%; структурно-функциональная резистентность эмали увеличилась на 37%.Заключение. Включение сильвинитотерапии в комплексное лечение больных хроническим генерализованным катаральным гингивитом оказывало выраженное положительное воздействие на состояние тканей пародонта и местный иммунитет полости рта

A joint Fermi-GBM and Swift-BAT analysis of gravitational-wave candidates from the third gravitational-wave observing run

We present Fermi Gamma-ray Burst Monitor (Fermi-GBM) and Swift Burst Alert Telescope (Swift-BAT) searches for gamma-ray/X-ray counterparts to gravitational-wave (GW) candidate events identified during the third observing run of the Advanced LIGO and Advanced Virgo detectors. Using Fermi-GBM onboard triggers and subthreshold gamma-ray burst (GRB) candidates found in the Fermi-GBM ground analyses, the Targeted Search and the Untargeted Search, we investigate whether there are any coincident GRBs associated with the GWs. We also search the Swift-BAT rate data around the GW times to determine whether a GRB counterpart is present. No counterparts are found. Using both the Fermi-GBM Targeted Search and the Swift-BAT search, we calculate flux upper limits and present joint upper limits on the gamma-ray luminosity of each GW. Given these limits, we constrain theoretical models for the emission of gamma rays from binary black hole mergers

Constraints on the cosmic expansion history from GWTC–3

We use 47 gravitational wave sources from the Third LIGO–Virgo–Kamioka Gravitational Wave Detector Gravitational Wave Transient Catalog (GWTC–3) to estimate the Hubble parameter H(z), including its current value, the Hubble constant H0. Each gravitational wave (GW) signal provides the luminosity distance to the source, and we estimate the corresponding redshift using two methods: the redshifted masses and a galaxy catalog. Using the binary black hole (BBH) redshifted masses, we simultaneously infer the source mass distribution and H(z). The source mass distribution displays a peak around 34 M⊙, followed by a drop-off. Assuming this mass scale does not evolve with the redshift results in a H(z) measurement, yielding ${H}_{0}={68}_{-8}^{+12}\,\mathrm{km}\ \,\ {{\rm{s}}}^{-1}\,{\mathrm{Mpc}}^{-1}$ (68% credible interval) when combined with the H0 measurement from GW170817 and its electromagnetic counterpart. This represents an improvement of 17% with respect to the H0 estimate from GWTC–1. The second method associates each GW event with its probable host galaxy in the catalog GLADE+, statistically marginalizing over the redshifts of each event's potential hosts. Assuming a fixed BBH population, we estimate a value of ${H}_{0}={68}_{-6}^{+8}\,\mathrm{km}\ \,\ {{\rm{s}}}^{-1}\,{\mathrm{Mpc}}^{-1}$ with the galaxy catalog method, an improvement of 42% with respect to our GWTC–1 result and 20% with respect to recent H0 studies using GWTC–2 events. However, we show that this result is strongly impacted by assumptions about the BBH source mass distribution; the only event which is not strongly impacted by such assumptions (and is thus informative about H0) is the well-localized event GW190814

Open data from the third observing run of LIGO, Virgo, KAGRA, and GEO

The global network of gravitational-wave observatories now includes five detectors, namely LIGO Hanford, LIGO Livingston, Virgo, KAGRA, and GEO 600. These detectors collected data during their third observing run, O3, composed of three phases: O3a starting in 2019 April and lasting six months, O3b starting in 2019 November and lasting five months, and O3GK starting in 2020 April and lasting two weeks. In this paper we describe these data and various other science products that can be freely accessed through the Gravitational Wave Open Science Center at https://gwosc.org. The main data set, consisting of the gravitational-wave strain time series that contains the astrophysical signals, is released together with supporting data useful for their analysis and documentation, tutorials, as well as analysis software packages

Search for gravitational-wave transients associated with magnetar bursts in advanced LIGO and advanced Virgo data from the third observing run

Gravitational waves are expected to be produced from neutron star oscillations associated with magnetar giant f lares and short bursts. We present the results of a search for short-duration (milliseconds to seconds) and longduration (∼100 s) transient gravitational waves from 13 magnetar short bursts observed during Advanced LIGO, Advanced Virgo, and KAGRA’s third observation run. These 13 bursts come from two magnetars, SGR1935 +2154 and SwiftJ1818.0−1607. We also include three other electromagnetic burst events detected by FermiGBM which were identified as likely coming from one or more magnetars, but they have no association with a known magnetar. No magnetar giant flares were detected during the analysis period. We find no evidence of gravitational waves associated with any of these 16 bursts. We place upper limits on the rms of the integrated incident gravitational-wave strain that reach 3.6 × 10−²³ Hz at 100 Hz for the short-duration search and 1.1 ×10−²² Hz at 450 Hz for the long-duration search. For a ringdown signal at 1590 Hz targeted by the short-duration search the limit is set to 2.3 × 10−²² Hz. Using the estimated distance to each magnetar, we derive upper limits upper limits on the emitted gravitational-wave energy of 1.5 × 1044 erg (1.0 × 1044 erg) for SGR 1935+2154 and 9.4 × 10^43 erg (1.3 × 1044 erg) for Swift J1818.0−1607, for the short-duration (long-duration) search. Assuming isotropic emission of electromagnetic radiation of the burst fluences, we constrain the ratio of gravitational-wave energy to electromagnetic energy for bursts from SGR 1935+2154 with the available fluence information. The lowest of these ratios is 4.5 × 103

The use of flour from germinated buckwheat in bread recipes

The results of the study of technological properties, chemical composition of buckwheat varieties of the Republic of Bashkortostan, as well as the effect of flour from sprouted buckwheat grain on the quality of wheat bread are presented. According to the nutritional value, in order to obtain buckwheat flour in order to include it in the bread recipe, the Inzer buckwheat variety was selected. The parameters of soaking and germination of buckwheat grain of this variety are optimized and it is shown that due to germination, the physico-chemical parameters of flour and its antioxidant activity are improved. Thus, the expediency of introducing flour from sprouted buckwheat grain into the recipe of wheat bread is proved. The optimal content of flour from sprouted buckwheat grain in the composition of a composite mixture with wheat flour of grade I, which amounted to 10%, providing an improvement in the organoleptic and physico-chemical parameters of bread, was established

Cyanoethylation of azafluorenes and syntheses of alcohols containing an azafluorene fragment

Isomeric (with respect to the position of the nitrogen atom) azafluorenes were cyanoethylated. The resulting 9,9-bis(β-cyanoethyl) derivatives were converted to the corresponding dibasic acids and their diesters. The latter were subjected to the Dieckmann reaction to obtain spiro compounds with azafluorene and cyclohexene fragments. The analogous spirans with 1,3-dioxalane and 1,3-dioxane rings were obtained from 3-methyl-2-azafluorenone. © 1983 Plenum Publishing Corporation