The Importance of Creative Industry Agglomerations in Explaining the Wealth of European Regions

This paper examines the existence of regional agglomerations of manufacturing, service and creative industries, the relationship between these industries and the wealth of regions and their industrial structure. Through an analysis of 250 European regions, three important conclusions can be inferred from the results obtained in this paper. The first is that creative industries play an important role in the wealth of a region. The second is that the most creative regions are characterized by having more high-tech manufacturing industries than the rest of the regions although the number of low-tech manufacturing firms is similar. Lastly, the industrial structure of each region has a greater influence on regional wealth than the existence of industrial agglomerations. The importance of this paper resides in the fact that up until now no analysis has demonstrated that creative industries are the most important industries in regional wealth.

Transcriptome of the deep-sea black scabbardfish, Aphanopus carbo (Perciformes: Trichiuridae) : tissue-specific expression patterns and candidate genes associated to depth adaptation

Deep-sea fishes provide a unique opportunity to study the physiology and evolutionary adaptation to extreme environments. We carried out a high throughput sequencing analysis on a 454 GS-FLX titanium plate using unnormalized cDNA libraries from six tissues of A. carbo. Assemblage and annotations were performed by Newbler and InterPro/Pfam analyses, respectively. The assembly of 544,491 high quality reads provided 8,319 contigs, 55.6% of which retrieved blast hits against the NCBI nonredundant database or were annotated with ESTscan. Comparison of functional genes at both the protein sequences and protein stability levels, associated with adaptations to depth, revealed similarities between A. carbo and other bathypelagic fishes. A selection of putative genes was standardized to evaluate the correlation between number of contigs and their normalized expression, as determined by qPCR amplification. The screening of the libraries contributed to the identification of new EST simple-sequence repeats (SSRs) and to the design of primer pairs suitable for population genetic studies as well as for tagging and mapping of genes. The characterization of the deep-sea fish A. carbo first transcriptome is expected to provide abundant resources for genetic, evolutionary, and ecological studies of this species and the basis for further investigation of depth-related adaptation processes in fishes.Publisher PDFPeer reviewe

Design of a Virtual Assistant to Improve Interaction Between the Audience and the Presenter

This article presents a novel design of a Virtual Assistant as part of a human-machine interaction system to improve communication between the presenter and the audience that can be used in education or general presentations for improving interaction during the presentations (e.g., auditoriums with 200 people). The main goal of the proposed model is the design of a framework of interaction to increase the level of attention of the public in key aspects of the presentation. In this manner, the collaboration between the presenter and Virtual Assistant could improve the level of learning among the public. The design of the Virtual Assistant relies on non-anthropomorphic forms with ‘live’ characteristics generating an intuitive and self-explainable interface. A set of intuitive and useful virtual interactions to support the presenter was designed. This design was validated from various types of the public with a psychological study based on a discrete emotions’ questionnaire confirming the adequacy of the proposed solution. The human-machine interaction system supporting the Virtual Assistant should automatically recognize the attention level of the audience from audiovisual resources and synchronize the Virtual Assistant with the presentation. The system involves a complex artificial intelligence architecture embracing perception of high-level features from audio and video, knowledge representation, and reasoning for pervasive and affective computing and reinforcement learning to teach the intelligent agent to decide on the best strategy to increase the level of attention of the audience

Complete breakdown of the Debye model of rotational relaxation near the isotropic-nematic phase boundary: Effects of intermolecular correlations in orientational dynamics

The Debye-Stokes-Einstein (DSE) model of rotational diffusion predicts that the rotational correlation times $\tau_{l}$ vary as $[l(l+1)]^{-1}$, where $l$ is the rank of the orientational correlation function (given in terms of the Legendre polynomial of rank $l$). One often finds significant deviation from this prediction, in either direction. In supercooled molecular liquids where the ratio $\tau_{1}/\tau_{2}$ falls considerably below three (the Debye limit), one usually invokes a jump diffusion model to explain the approach of the ratio $\tau_{1}/\tau_{2}$ to unity. Here we show in a computer simulation study of a standard model system for thermotropic liquid crystals that this ratio becomes much less than unity as the isotropic-nematic phase boundary is approached from the isotropic side. Simultaneously, the ratio $\tau_2/\eta$ (where $\eta$ is the shear viscosity of the liquid) becomes {\it much larger} than hydrodynamic value near the I-N transition. We have also analyzed the break down of the Debye model of rotational diffusion in ratios of higher order rotational correlation times. We show that the break down of the DSE model is due to the growth of orientational pair correlation and provide a mode coupling theory analysis to explain the results.Comment: Submitted to Physical Review

Creative clusters in Europe: a microdata approach

Creative industries are highly concentrated forming clusters. One of the main problems for the identification of clusters of creative industries in Europe is the lack of data, constrained in practice to regions (NUTS 2) and influenced by the heterogeneity in the definition of NUTS across countries. This research uses firm-level data geo-referenced at address level and geostatistical modeling to identify clusters of creative industries in fifteen European countries. The procedure is independent of administrative divisions and national boundaries and allows to produce a precise geography of the clusters of creative industries in Europe.

Discretization-related issues in the KPZ equation: Consistency, Galilean-invariance violation, and fluctuation--dissipation relation

In order to perform numerical simulations of the KPZ equation, in any dimensionality, a spatial discretization scheme must be prescribed. The known fact that the KPZ equation can be obtained as a result of a Hopf--Cole transformation applied to a diffusion equation (with \emph{multiplicative} noise) is shown here to strongly restrict the arbitrariness in the choice of spatial discretization schemes. On one hand, the discretization prescriptions for the Laplacian and the nonlinear (KPZ) term cannot be independently chosen. On the other hand, since the discretization is an operation performed on \emph{space} and the Hopf--Cole transformation is \emph{local} both in space and time, the former should be the same regardless of the field to which it is applied. It is shown that whereas some discretization schemes pass both consistency tests, known examples in the literature do not. The requirement of consistency for the discretization of Lyapunov functionals is argued to be a natural and safe starting point in choosing spatial discretization schemes. We also analyze the relation between real-space and pseudo-spectral discrete representations. In addition we discuss the relevance of the Galilean invariance violation in these consistent discretization schemes, and the alleged conflict of standard discretization with the fluctuation--dissipation theorem, peculiar of 1D.Comment: RevTex, 23pgs, 2 figures, submitted to Phys. Rev.

Estudio de la microfiltración: modificación a un método

De los múltiples y sofisticados sistemas de estudio de la microfiltración que existen hoy día, el más utilizado por ser el más accesible es el de la penetración de colorantes. Básicamente consiste en la introducción en los dientes extraídos y restaurados en el colorante por un tiempo determinado, con o sin termociclado previo. El diente se secciona y se observa, valorando según distintas escalas el grado de filtración. Varios son los inconvenientes de este sistema: arbitrariedad en la elección de colorante, en su concentración y tiempo de inmersión, visión bidimensional en cortes no estandarizados, y condiciones no fisiológicas. El método que porponemos en este estudio aporta: - presión intrapulpar simulada constante durante todo el proceso de adhesión y filtración, - desgaste progresivo que permite visualizar toda la interfase, obteniendo así una visión tridimensional, -método sencillo y accesible.// Of the multiple and sophisticated systems for studying microfiltration available today, the most commonly used, due to its being the most accesible is that of dye penetration. This basically consist of the inmersion of the extracted and restored teeth in the dye solution for a fixed amount of time, with or without previous thermocycling. The tooth is sectioned and studied the level of filtration is assessed according to distinct scales. There are several disadvantages to this system namely the arbitrary selection of the dye, its concentration and the duraction of the inmersion, the two-dimensional view of random cuts and the absence of physiological conditions. The method we propose in this study have the following advantages: - constant, simulated intrapulpal pressure during the whole process of adhesion and filtration, - progressive and controlled wear wich would allow the whole interphase to be studied three-dimensionally, - simplicity and accesibility

Heat exchange between two interacting nanoparticles beyond the fluctuation-dissipation regime

We show that the observed non-monotonic behavior of the thermal conductance between two nanoparticles when they are brought into contact is originated by an intricate phase space dynamics. Here it is assumed that this dynamics results from the thermally activated jumping through a rough energy landscape. A hierarchy of relaxation times plays the key role in the description of this complex phase space behaviour. Our theory enables us to analyze the heat transfer just before and at the moment of contact.Comment: 4 pages, 1 figure, approved for publication in Physical Review Letter