Hurewicz fibrations, almost submetries and critical points of smooth maps

We prove that the existence of a Hurewicz fibration between certain spaces with the homotopy type of a CW-complex implies some topological restrictions on their universal coverings. This result is used to deduce differentiable and metric properties of maps between compact Riemannian manifolds under curvature restrictions

Some triviality results for quasi-Einstein manifolds and Einstein warped products

In this paper we prove a number of triviality results for Einstein warped products and quasi-Einstein manifolds using different techniques and under assumptions of various nature. In particular we obtain and exploit gradient estimates for solutions of weighted Poisson-type equations and adaptations to the weighted setting of some Liouville-type theorems.Comment: 15 pages, fixed minor mistakes in Section

Some non-linear function theoretic properties of Riemannian manifolds

We study the appropriate versions of parabolicity stochastic completeness and related Liouville properties for a general class of operators which include the $p$-Laplace operator, and the non linear singular operators in non-diagonal form considered by J. Serrin and collaborators

A finiteness theorem for the space of Lp harmonic sections

In this paper we give a unified and improved treatment to finite dimensionality results for subspaces of Lp harmonic sections of Riemannian or Hermitian vector bundles over complete manifolds. The geometric conditions on the manifold are subsumed by the assumption that the Morse index of a related Schro \u308dinger operator is finite. Applications of the finiteness theorem to concrete geometric situations are also presented

Reverse Khas'minskii condition

The aim of this paper is to present and discuss some equivalent characterizations of p-parabolicity in terms of existence of special exhaustion functions. In particular, Khas'minskii in [K] proved that if there exists a 2-superharmonic function k defined outside a compact set such that $\lim_{x\to \infty} k(x)=\infty$, then R is 2-parabolic, and Sario and Nakai in [SN] were able to improve this result by showing that R is 2-parabolic if and only if there exists an Evans potential, i.e. a 2-harmonic function $E:R\setminus K \to \R^+$ with \lim_{x\to \infty} \E(x)=\infty. In this paper, we will prove a reverse Khas'minskii condition valid for any p>1 and discuss the existence of Evans potentials in the nonlinear case.Comment: final version of the article available at http://www.springer.co

The mean curvature of cylindrically bounded submanifolds

We give an estimate of the mean curvature of a complete submanifold lying inside a closed cylinder $B(r)\times\R^{\ell}$ in a product Riemannian manifold $N^{n-\ell}\times\R^{\ell}$. It follows that a complete hypersurface of given constant mean curvature lying inside a closed circular cylinder in Euclidean space cannot be proper if the circular base is of sufficiently small radius. In particular, any possible counterexample to a conjecture of Calabion complete minimal hypersurfaces cannot be proper. As another application of our method, we derive a result about the stochastic incompleteness of submanifolds with sufficiently small mean curvature.Comment: First version (December 2008). Final version, including new title (February 2009). To appear in Mathematische Annale

The H\"older-Poincar\'e Duality for Lq,pL_{q,p}-cohomology

We prove the following version of Poincare duality for reduced $L_{q,p}$-cohomology: For any $1<q,p<\infty$, the $L_{q,p}$-cohomology of a Riemannian manifold is in duality with the interior $L_{p',q'}-cohomology for$1/p+1/p'=1$,$1/q+1/q'=1$.Comment: 21 page

Myers' type theorems and some related oscillation results

In this paper we study the behavior of solutions of a second order differential equation. The existence of a zero and its localization allow us to get some compactness results. In particular we obtain a Myers' type theorem even in the presence of an amount of negative curvature. The technique we use also applies to the study of spectral properties of Schroedinger operators on complete manifolds.Comment: 16 page

Height estimates for Killing graphs

The paper aims at proving global height estimates for Killing graphs defined over a complete manifold with nonempty boundary. To this end, we first point out how the geometric analysis on a Killing graph is naturally related to a weighted manifold structure, where the weight is defined in terms of the length of the Killing vector field. According to this viewpoint, we introduce some potential theory on weighted manifolds with boundary and we prove a weighted volume estimate for intrinsic balls on the Killing graph. Finally, using these tools, we provide the desired estimate for the weighted height in the assumption that the Killing graph has constant weighted mean curvature and the weighted geometry of the ambient space is suitably controlled.Comment: 26 pages. Final version. To appear on Journal of Geometric Analysi

Sequence similarity is more relevant than species specificity in probabilistic backtranslation

BACKGROUND: Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module. The degeneracy of the genetic code makes backtranslation potentially ambiguous since most amino acids are encoded by multiple codons. The common approach to overcome this difficulty is based on imitation of codon usage within the target species. RESULTS: This paper describes EasyBack, a new parameter-free, fully-automated software for backtranslation using Hidden Markov Models. EasyBack is not based on imitation of codon usage within the target species, but instead uses a sequence-similarity criterion. The model is trained with a set of proteins with known cDNA coding sequences, constructed from the input protein by querying the NCBI databases with BLAST. Unlike existing software, the proposed method allows the quality of prediction to be estimated. When tested on a group of proteins that show different degrees of sequence conservation, EasyBack outperforms other published methods in terms of precision. CONCLUSION: The prediction quality of a protein backtranslation methis markedly increased by replacing the criterion of most used codon in the same species with a Hidden Markov Model trained with a set of most similar sequences from all species. Moreover, the proposed method allows the quality of prediction to be estimated probabilistically