Scalable quantum memory in the ultrastrong coupling regime

Circuit quantum electrodynamics, consisting of superconducting artificial atoms coupled to on-chip resonators, represents a prime candidate to implement the scalable quantum computing architecture because of the presence of good tunability and controllability. Furthermore, recent advances have pushed the technology towards the ultrastrong coupling regime of light-matter interaction, where the qubit-resonator coupling strength reaches a considerable fraction of the resonator frequency. Here, we propose a qubit-resonator system operating in that regime, as a quantum memory device and study the storage and retrieval of quantum information in and from the Z2 parity-protected quantum memory, within experimentally feasible schemes. We are also convinced that our proposal might pave a way to realize a scalable quantum random-access memory due to its fast storage and readout performances.Comment: We have updated the title, abstract and included a new section on the open-system dynamic

An empiric on geopolitical risk and the tourism-economic growth nexus

Purpose – This study empirically examines the moderating role of geopolitical risk on the tourism-economic growth nexus by applying a recent geopolitical risk indicator developed by Caldara and Iacoviello (2022) in a cross-country panel data growth model context for a sample of 24 countries.Design/methodology/approach – A Dummy Variable Least Squares (DVLS) panel data model, nonparametric covariance matrix estimator and SYS-GMM estimation techniques are employed for the analysis. We capture the GPR moderating effect by disaggregating the cross-country sample according to low vs. high country GPR score and through a GPR interaction coefficient. Several controls are included in our models such as gross fixed capital formation and - consistent with Barro (1990) - government consumption. Trade openness is used to account for the export-led growth effect. In line with neoclassical growth theory (e.g., Barro, 1991) we also include the real interest rate, to account for policy makers’ commitment to macroeconomic stability, financial depth, as a proxy for financial development, population growth, and the level of secondary school education. We also control for unobserved country-specific and time-invariant effects.Findings – The research finds that the interaction term of geopolitical risk significantly contributes to the predictive ability of the regression and provides empirical evidence that confirms that only in low geopolitical risk countries international tourism positively and significantly contributes to economic growth. Important theoretical and policy implications flow from these findings.Originality/value – The study not only contributes to advancing academic knowledge on the tourism-growth nexus, it also has impact beyond academia. Many countries have in the past pursued, and many continue to pursue, tourism specialization and/or tourism-led growth strategies based on the theoretically well-established and empirically validated positive link between inbound tourism and economic growth. Our findings alert policy makers in such countries to the significant moderating role that geopolitical risk plays in affecting the above-mentioned relationship and to the importance of prioritizing geopolitical stability as a policy precursor for the successful implementation of such strategies

A non-contact capacitance type level transducer for liquid characterization

The liquid properties such as buoyancy, pressure at a depth, relative electrical permittivity, electrical conductivity, thermal conductivity, absorption of radiation, liquid surface reflection of sound or light waves, are used to design the different types of liquid level transducers for liquid level measurement in any process industry. The contact-type level-sensing transducers have the disadvantage that their characteristic properties may change due to physical or chemical reaction between the liquid and the probing material, and hence may affect accuracy besides their life time. The non-contact-type level-sensing probes may have longer life period, but they are comparatively costly and require various environmental and experimental precautionary measures when being used. In this paper, a low-cost non-contact capacitance type liquid level measuring technique has been designed and used for liquid identification objectives. The results obtained are very much consistent with the theoretical derivations

Quantum computer-aided design of quantum optics hardware

The parameters of a quantum system grow exponentially with the number of involved quantum particles. Hence, the associated memory requirement to store or manipulate the underlying wavefunction goes well beyond the limit of the best classical computers for quantum systems composed of a few dozen particles, leading to serious challenges in their numerical simulation. This implies that the verification and design of new quantum devices and experiments are fundamentally limited to small system size. It is not clear how the full potential of large quantum systems can be exploited. Here, we present the concept of quantum computer designed quantum hardware and apply it to the field of quantum optics. Specifically, we map complex experimental hardware for high-dimensional, many-body entangled photons into a gate-based quantum circuit. We show explicitly how digital quantum simulation of Boson sampling experiments can be realized. We then illustrate how to design quantum-optical setups for complex entangled photonic systems, such as high-dimensional Greenberger-Horne-Zeilinger states and their derivatives. Since photonic hardware is already on the edge of quantum supremacy and the development of gate-based quantum computers is rapidly advancing, our approach promises to be a useful tool for the future of quantum device design

Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison.

BACKGROUND: Artemisinin-based combinations are judged the best treatments for multidrug-resistant Plasmodium falciparum malaria. Artesunate-mefloquine is widely recommended in southeast Asia, but its high cost and tolerability profile remain obstacles to widespread deployment. To assess whether dihydroartemisinin-piperaquine is a suitable alternative to artesunate-mefloquine, we compared the safety, tolerability, efficacy, and effectiveness of the two regimens for the treatment of uncomplicated falciparum in western Myanmar (Burma). METHODS: We did an open randomised comparison of 3-day regimens of artesunate-mefloquine (12/25 mg/kg) versus dihydroartemisinin-piperaquine (6.3/50 mg/kg) for the treatment of children aged 1 year or older and in adults with uncomplicated falciparum malaria in Rakhine State, western Myanmar. Within each group, patients were randomly assigned supervised or non-supervised treatment. The primary endpoint was the PCR-confirmed parasitological failure rate by day 42. Failure rates at day 42 were estimated by Kaplan-Meier survival analysis. This study is registered as an International Standard Randomised Controlled Trial, number ISRCTN27914471. FINDINGS: Of 652 patients enrolled, 327 were assigned dihydroartemisinin-piperaquine (156 supervised and 171 not supervised), and 325 artesunate-mefloquine (162 and 163, respectively). 16 patients were lost to follow-up, and one patient died 22 days after receiving dihydroartemisinin-piperaquine. Recrudescent parasitaemias were confirmed in only two patients; the day 42 failure rate was 0.6% (95% CI 0.2-2.5) for dihydroartemisinin-piperaquine and 0 (0-1.2) for artesunate-mefloquine. Whole-blood piperaquine concentrations at day 7 were similar for patients with observed and non-observed dihydroartemisinin-piperaquine treatment. Gametocytaemia developed more frequently in patients who had received dihydroartemisinin-piperaquine than in those on artesunate-mefloquine: day 7, 18 (10%) of 188 versus five (2%) of 218; relative risk 4.2 (1.6-11.0) p=0.011. INTERPRETATION: Dihydroartemisinin-piperaquine is a highly efficacious and inexpensive treatment of multidrug-resistant falciparum malaria and is well tolerated by all age groups. The effectiveness of the unsupervised treatment, as in the usual context of use, equalled its supervised efficacy, indicating good adherence without supervision. Dihydroartemisinin-piperaquine is a good alternative to artesunate-mefloquine

Scanning Electron Microscopy of Cyclosporine-Induced Gingival Overgrowth

Overgrown human gingival specimens were examined histologically and by scanning electron microscopy (SEM) to study structural changes caused by cyclosporine. The biopsy specimens were from organ transplant recipients receiving cyclosporine to suppress the rejection of the transplanted organ. The epithelium of the overgrown gingiva was thickened, acanthotic and parakeratotic. Retepegs were anastomosing and extending into connective tissue. The SEM examination of the outer surface of the attached gingival showed loss of cellular attachments and cells were exfoliating. The normal honeycomb structure formed by interconnecting microvilli surrounding the pits was distorted. Outer gingival cell surface showed numerous round, ovoid and dome-like structures instead of parallel, reticular or fingerprint-like microridges. It was concluded that cyclosporine not only caused hyperplasia but also changed the structure of the outer epithelial cell surface

Modelling the coefficient of thermal expansion in Ni-based superalloys and bond coatings

The coefficient of thermal expansion (CTE) of nickel-based superalloys and bond coat layers was modelled by considering contributions from their constituent phases. The equilibrium phase composition of the examined materials was determined using thermodynamic equilibrium software with an appropriate database for Ni-based alloys, whereas the CTE and elastic properties of the principal phases were modelled using published data. The CTEs of individual phases were combined using a number of approaches to determine the CTE of the phase aggregate. As part of this work, the expansion coefficients of the superalloy IN-738LC and bond coat Amdry-995 were measured as a function of temperature and compared with the model predictions. The predicted values were also validated with the published data for the single-crystal superalloy CMSX-4 and a number of other Ni-based alloy compositions at 1000 K. A very good agreement between experiment and model output was found, especially up to 800  $$^\circ$$ � C. The modelling approaches discussed in this paper have the potential to be an extremely useful tool for the industry and for the designers of new coating systems

Quantum computer-aided design of quantum optics hardware

The parameters of a quantum system grow exponentially with the number of involved quantum particles. Hence, the associated memory requirement to store or manipulate the underlying wavefunction goes well beyond the limit of the best classical computers for quantum systems composed of a few dozen particles, leading to serious challenges in their numerical simulation. This implies that the verification and design of new quantum devices and experiments are fundamentally limited to small system size. It is not clear how the full potential of large quantum systems can be exploited. Here, we present the concept of quantum computer designed quantum hardware and apply it to the field of quantum optics. Specifically, we map complex experimental hardware for high-dimensional, many-body entangled photons into a gate-based quantum circuit. We show explicitly how digital quantum simulation of Boson sampling experiments can be realized. We then illustrate how to design quantum-optical setups for complex entangled photonic systems, such as high-dimensional Greenberger–Horne–Zeilinger states and their derivatives. Since photonic hardware is already on the edge of quantum supremacy and the development of gate-based quantum computers is rapidly advancing, our approach promises to be a useful tool for the future of quantum device design