Semi-relativistic charge-current density operator

The charge-current density and two-photon operators consistent with a single-particle semi-relativistic Hamiltonian are derived within a suitable functional derivative formalism which preserves gauge invariance. An application to electron scattering is presented and results are compared with a fully relativistic case and the non-relativistic cases corrected through fourth order in M^{-1}.Comment: 20 pages, 3 postscript figures, typos correcte

Spin-polarization-induced structural selectivity in Pd3X_3X and Pt3X_3X (X=3dX=3d) compounds

Spin-polarization is known to lead to important {\it magnetic} and {\it optical} effects in open-shell atoms and elemental solids, but has rarely been implicated in controlling {\it structural} selectivity in compounds and alloys. Here we show that spin-polarized electronic structure calculations are crucial for predicting the correct $T=0$ crystal structures for Pd$_3X$ and Pt$_3X$ compounds. Spin-polarization leads to (i) stabilization of the $L1_2$ structure over the $DO_{22}$ structure in Pt$_3$Cr, Pd$_3$Cr, and Pd$_3$Mn, (ii) to the stabilization of the $DO_{22}$ structure over the $L1_2$ structure in Pd$_3$Co and to (iii) ordering (rather than phase-separation) in Pt$_3$Co and Pd$_3$Cr. The results are analyzed in terms of first-principles local spin density calculations.Comment: 4 pages, REVTEX, 3 eps figures, to appear in PR

Economic impact and risk analysis of integrating sustainable aviation fuels into refineries

The growth of the aviation industry coupled with its dependence on energy dense, liquid fuels has brought sustainable aviation fuel (SAF) research to the forefront of the biofuels community. Petroleum refineries will need to decide how to satisfy the projected increase in jet fuel demand with either capital investments to debottleneck current operations or by integrating bio-blendstocks. This work seeks to compare jet production strategies on a risk-adjusted, economic performance basis using Monte-Carlo simulation and refinery optimization models. Additionally, incentive structures aiming to de-risk initial SAF production from the refiner’s perspective are explored. Results show that market sensitive incentives can reduce the financial risks associated with producing SAFs and deliver marginal abatement costs ranging between 136-182 $/Ton-CO2e

Specific heat of quasi-2D antiferromagnetic Heisenberg models with varying inter-planar couplings

We have used the stochastic series expansion (SSE) quantum Monte Carlo (QMC) method to study the three-dimensional (3D) antiferromagnetic Heisenberg model on cubic lattices with in-plane coupling J and varying inter-plane coupling J_perp < J. The specific heat curves exhibit a 3D ordering peak as well as a broad maximum arising from short-range 2D order. For J_perp << J, there is a clear separation of the two peaks. In the simulations, the contributions to the total specific heat from the ordering across and within the layers can be separated, and this enables us to study in detail the 3D peak around T_c (which otherwise typically is dominated by statistical noise). We find that the peak height decreases with decreasing J_perp, becoming nearly linear below J_perp = 0.2J. The relevance of these results to the lack of observed specific heat anomaly at the ordering transition of some quasi-2D antiferromagnets is discussed.Comment: 7 pages, 8 figure

The detection of the imprint of filaments on cosmic microwave background lensing

Galaxy redshift surveys, such as 2dF, SDSS, 6df, GAMA and VIPERS, have shown that the spatial distribution of matter forms a rich web, known as the cosmic web. The majority of galaxy survey analyses measure the amplitude of galaxy clustering as a function of scale, ignoring information beyond a small number of summary statistics. Since the matter density field becomes highly non-Gaussian as structure evolves under gravity, we expect other statistical descriptions of the field to provide us with additional information. One way to study the non-Gaussianity is to study filaments, which evolve non-linearly from the initial density fluctuations produced in the primordial Universe. In our study, we report the first detection of CMB (Cosmic Microwave Background) lensing by filaments and we apply a null test to confirm our detection. Furthermore, we propose a phenomenological model to interpret the detected signal and we measure how filaments trace the matter distribution on large scales through filament bias, which we measure to be around 1.5. Our study provides a new scope to understand the environmental dependence of galaxy formation. In the future, the joint analysis of lensing and Sunyaev-Zel'dovich observations might reveal the properties of `missing baryons', the vast majority of the gas which resides in the intergalactic medium and has so far evaded most observations

Nucleon to Delta Weak Excitation Amplitudes in the Non-relativistic Quark Model

We investigate the nucleon to Delta(1232) vector and axial vector amplitudes in the non-relativistic quark model of the Isgur-Karl variety. A particular interest is to investigate the SU(6) symmetry breaking, due to color hyperfine interaction. We compare the theoretical estimates to recent experimental investigation of the Adler amplitudes by neutrino scattering.Comment: \documentstyle[aps]{revtex}, 21pages; 11 postscript figures. Accepted for publication by Phys. Rev.

Scattering of long wavelengths into thin silicon photovoltaic films by plasmonic silver nanoparticles

Nanoparticles and nanostructures with plasmonic resonances are currently being employed to enhance the efficiency of solar cells. Ag stripe arrays have been shown theoretically to enhance the short-circuit current of thin silicon layers. Monolayers of Ag nanoparticles with diameter d < 300 nm have shown strong plasmonic resonances when coated in thin polymer layers with thicknesses < d. We study experimentally the diffuse vs. specular scattering from monolayer arrays of Ag nanoparticles (spheres and prisms with diameters in the range 50 – 300 nm) coated onto the front side of thin (100 nm < t < 500 nm) silicon films deposited on glass and flexible polymer substrates, the latter originating in a roll-to-roll manufacturing process. Ag nanoparticles are held in place and aggregation is prevented with a polymer overcoat. We observe interesting wavelength shifts between maxima in specular and diffuse scattering that depend on particle size and shape, indicating that the nanoparticles substantially modify the scattering into the thin silicon film.United States. Air Force (United States. Army. Natick Soldier Research Development and Engineering Center Contract FA8721-05-C-0002)Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies (Contract W911NF-07-D0004

Exact spectra, spin susceptibilities and order parameter of the quantum Heisenberg antiferromagnet on the triangular lattice

Exact spectra of periodic samples are computed up to $N=36$. Evidence of an extensive set of low lying levels, lower than the softest magnons, is exhibited. These low lying quantum states are degenerated in the thermodynamic limit; their symmetries and dynamics as well as their finite-size scaling are strong arguments in favor of N\'eel order. It is shown that the N\'eel order parameter agrees with first-order spin-wave calculations. A simple explanation of the low energy dynamics is given as well as the numerical determinations of the energies, order parameter and spin susceptibilities of the studied samples. It is shown how suitable boundary conditions, which do not frustrate N\'eel order, allow the study of samples with $N=3p+1$ spins. A thorough study of these situations is done in parallel with the more conventional case $N=3p$.Comment: 36 pages, REVTeX 3.0, 13 figures available upon request, LPTL preprin

Adaptive RSK-EphA2-GPRC5A signaling switch triggers chemotherapy resistance in ovarian cancer

Metastatic cancers commonly activate adaptive chemotherapy resistance, attributed to both microenvironment-dependent phenotypic plasticity and genetic characteristics of cancer cells. However, the contribution of chemotherapy itself to the non-genetic resistance mechanisms was long neglected. Using high-grade serous ovarian cancer (HGSC) patient material and cell lines, we describe here an unexpectedly robust cisplatin and carboplatin chemotherapy-induced ERK1/2-RSK1/2-EphA2-GPRC5A signaling switch associated with cancer cell intrinsic and acquired chemoresistance. Mechanistically, pharmacological inhibition or knockdown of RSK1/2 prevented oncogenic EphA2-S897 phosphorylation and EphA2-GPRC5A co-regulation, thereby facilitating a signaling shift to the canonical tumor-suppressive tyrosine phosphorylation and consequent downregulation of EphA2. In combination with platinum, RSK inhibitors effectively sensitized even the most platinum-resistant EphA2(high), GPRC5A(high) cells to the therapy-induced apoptosis. In HGSC patient tumors, this orphan receptor GPRC5A was expressed exclusively in cancer cells and associated with chemotherapy resistance and poor survival. Our results reveal a kinase signaling pathway uniquely activated by platinum to elicit adaptive resistance. They further identify GPRC5A as a marker for abysmal HGSC outcome and putative vulnerability of the chemo-resistant cells to RSK1/2-EphA2-pS897 pathway inhibition.Peer reviewe

Responses to the 2017 ‘1 Million Gray Question’: ASTRO membership’s opinions on the most important research question facing radiation oncology

At the American Society for Radiation Oncology's (ASTRO's) 2017 annual meeting in San Diego, CA, attendees were asked, “What is the most important research question that needs to be answered in the next 3 to 5 years?” This request was meant to start a dialogue, promote thoughtful discussion within our professional community, and help inform topics for ASTRO workshops and focus meetings. Nearly 100 people responded while in attendance at the meeting, with questions that ranged from “How can we remove barriers so low- and middle-income countries can have radiation oncology facilities?” to “What is the exact role of radiation in stage IV disease in combination with immunotherapy or targeted agents to combat resistance development?” to “How can personalized care be better integrated into the oncology and radiation oncology clinical space?