218 research outputs found
Steady states of lattice population models with immigration
In a lattice population model where individuals evolve as subcritical branching random walks subject to external immigration, the cumulants are estimated and the existence of the steady state is proved. The resulting dynamics are Lyapunov stable in that their qualitative behavior does not change under suitable perturbations of the main parameters of the model. An explicit formula of the limit distribution is derived in the solvable case of no birth. Monte Carlo simulation shows the limit distribution in the solvable case
Características educacionais da prática de fala do moderno russo: Uma visão destacada de um observador educado
The article concentrates on the educational features of modern everyday communication. The materials used were texts of notices that prove the existence of a crisis in modern mass communication. The reasons of crisis phenomena in speech practice have been established and ways out of the situation have been suggested.El artículo se concentra en las características educativas de la comunicación cotidiana moderna. Los materiales utilizados fueron textos de aviso que prueban la existencia de una crisis en la comunicación de masas moderna. Se han establecido las razones de los fenómenos de crisis en la práctica del habla y se han sugerido las formas de salir de la situación.O artigo concentra-se nas características educacionais da comunicação cotidiana moderna. Os materiais utilizados foram textos de avisos que comprovam a existência de uma crise na comunicação de massa moderna. As razões dos fenômenos de crise na prática da fala foram estabelecidas e as saídas para a situação foram sugeridas
Representação linguística da noção "crianças migrantes" na consciência naiva de oradores russos nativos
The article deals with the linguistic representation of the notion of "migrant children" in the naive consciousness of native Russian speakers. The notion under study correlates with the worldview as an integral image of the world in a person's mind. As the worldview is a multilevel phenomenon, there are different levels of generalization and representation of knowledge. Usually, the linguistic worldview is investigated precisely in relation to the specific ethnocultural features of a particular people and correlates with large ethnocultural groups. Based on the associates obtained as a result of a free association experiment, a field model of the concept of "migrant children" is developed.El artículo trata de la representación lingüística de la noción de "niños migrantes" en la conciencia ingenua de los hablantes nativos de ruso. La noción en estudio se correlaciona con la cosmovisión como una imagen integral del mundo en la mente de una persona. Como la cosmovisión es un fenómeno multinivel, existen diferentes niveles de generalización y representación del conocimiento. Por lo general, la cosmovisión lingüística se investiga precisamente en relación con las características etnoculturales específicas de un pueblo en particular y se correlaciona con grandes grupos etnoculturales. A partir de los asociados obtenidos como resultado de un experimento de libre asociación, se desarrolla un modelo de campo del concepto de "niños migrantes".O artigo trata da representação linguística da noção de "crianças migrantes" na consciência ingênua de falantes nativos de russo. A noção em estudo se correlaciona com a visão de mundo como uma imagem integral do mundo na mente de uma pessoa. Como a cosmovisão é um fenômeno multinível, existem diferentes níveis de generalização e representação do conhecimento. Normalmente, a visão de mundo linguística é investigada precisamente em relação às características etnoculturais específicas de um determinado povo e se correlaciona com grandes grupos etnoculturais. Com base nos associados obtidos como resultado de uma experiência de associação livre, é desenvolvido um modelo de campo do conceito de "crianças migrantes"
ОРГАНІЗАЦІЯ НАВЧАЛЬНОГО ПРОЦЕСУ ВИКЛАДАННЯ ДИСЦИПЛІН “МЕДИЧНА ХІМІЯ” ТА “БІООРГАНІЧНА ХІМІЯ” ДЛЯ ІНОЗЕМНИХ СТУДЕНТІВ I КУРСУ МЕДИЧНИХ ТА СТОМАТОЛОГІЧНОГО ФАКУЛЬТЕТІВ ЗА УМОВ КРЕДИТНО-ТРАНСФЕРНОЇ СИСТЕМИ НАВЧАННЯ
The article presents the principle of construction of education process of Medical Chemistry and Bio-organic chemistry for students of the І-st course in Medical and Stomatology Faculties according to the principle of credit-transfer system.У статті розглянуто принцип побудови навчального процесу викладання дисциплін “Медична хімія” та “Біоорганічна хімія” для іноземних студентів І курсу медичних та стоматологічного факультетів за умов кредитно- трансферної системи
Endobronchial Ultrasound in Mediastinal Lymphadenopathy
Currently, endobronchial ultrasound dramatically changed diagnostic approaches for mediastinal lesions, both benign and malignant. Still there is a lack of data regarding the optimal anaesthesia, route of intubation, needle type, and specific clinical situations concerning EBUS in real clinical practice. A short, but clinically oriented, description of EBUS-TBNA and EUS-b-FNA techniques for mediastinal lesions is provided
Investigation of 5’-norcarbocyclic nucleoside analogues as antiprotozoal and antibacterial agents
Carbocyclic nucleosides have long played a role in antiviral, antiparasitic, and antibacterial therapies. Recent results from our laboratories from two structurally related scaffolds have shown promising activity against both Mycobacterium tuberculosis and several parasitic strains. As a result, a small structure activity relationship study was designed to further probe their activity and potential. Their synthesis and the results of the subsequent biological activity are reported herein
Therapeutic Effects of Mycobacterial Secretory Proteins Against Established Asthma in BALB/c Mice
Microbiological diagnosis of coincident mycobacterial infection in cystic Fibrosis
Diseases caused by mycobacteria, leprosy and tuberculosis, are widely known for many centuries. However, interest in mycobacteriosis, as an infectious disease of human organs caused by other mycobacteria, was only apparent from the late 50s of the 20th century. Over the years of observation, the number of cases of mycobacteriosis in various regions of the world has increased significantly, including in patients with cystic fibrosis. A key sign of comorbidity in cystic fibrosis is a chronic microbial infection that determines the severity of the course and the prognosis of the disease. In order to identify and identify mycobacteria isolated from patients with cystic fibrosis from 2011 to 2018, sputum was examined from 160 patients with cystic fibrosis and suspected mycobacterial infection. Mycobacteria were secreted in 17 (10.6%) patients with cystic fibrosis, of which non-tuberculous mycobacteria predominated. Thirteen patients were infected with M. abscessus (76.4%), two with M.avium (11.7%), one with M.xenopi (5.8%), one with M. tuberculosis (5.8%). Determination of drug sensitivity of mycobacteria showed that the culture of M.tuberculosis was sensitive to all antituberculosis drugs, and strains of nontuberculous mycobacteria had a different spectrum of drug susceptibility to drugs used for the therapy of mycobacteriosis. Identification of infectious agents will help ensure the timely initiation of adequate treatment, proper monitoring and prevention of the spread of non-tuberculosis mycobacteria among patients with cystic fibrosis.Заболевания, вызываемые микобактериями, лепра и туберкулез, широко известны на протяжении многих столетий. Однако интерес к микобактериозу, как инфекционному поражению органов человека, вызываемому другими микобактериями, проявился только с конца 50-х годов ХХ века. За годы наблюдений число случаев заболевания микобактериозом в различных регионах мира значительно увеличилось, в том числе и у больных муковисцидозом. ключевой признак коморбидности при муковисцидозе - хроническая микробная инфекция, которая определяет тяжесть течения и прогноз заболевания. С целью выявления и идентификация микобактерий, выделенных от больных муковисцидозом за период с 2011 по 2018 год, была исследована мокрота от 160 пациентов с муковисцидозом и подозрением на микобактериальную инфекцию. У 17 (10,6%) пациентов с муковисцидозом были выделены микобактерии, из них преобладали нетуберкулезные микобактерии. Тринадцать пациентов были инфицированы M.abscessus(76,4%), два - M.avium (11,7%), один - M.xenopi (5,8%), один - M.tuberculosis (5,8%). определение лекарственной чувствительности микобактерий показало, что, культура M.tuberculosis была чувствительна ко всем противотуберкулезным препаратам, а штаммы нетуберкулезных микобактерий имели различный спектр лекарственной чувствительности к препаратам, применяемым для терапии микобактериозов. Идентификация возбудителей инфекции будет способствовать обеспечению своевременного начала адекватного лечения, надлежащего мониторинга и профилактики распространения нетуберкулезных микобактерий среди больных кистозным фиброзом (муковисцидозом)
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