Thermal conductivity of heterogeneous mixtures and lunar soils

The theoretical evaluation of the effective thermal conductivity of granular materials is discussed with emphasis upon the heat transport properties of lunar soil. The following types of models are compared: probabilistic, parallel isotherm, stochastic, lunar, and a model based on nonlinear heat flow system synthesis

Differentiating Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features from Classic Papillary Thyroid Carcinoma: Analysis of Cytomorphologic Descriptions Using a Novel Machine-Learning Approach.

Background:Recent studies show various cytomorphologic features that can assist in the differentiation of classic papillary thyroid carcinoma (cPTC) from noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). Differentiating these two entities changes the clinical management significantly. We evaluated the performance of support vector machine (SVM), a machine learning algorithm, in differentiating cases of NIFTP and encapsulated follicular variant of papillary thyroid carcinoma with no capsular or lymphovascular invasion (EFVPTC) from cases of cPTC with the use of microscopic descriptions. SVM is a supervised learning algorithm used in classification problems. It assigns the input data to one of two categories by building a model based on a set of training examples (learning) and then using that learned model to classify new examples. Methods:Surgical pathology cases with the diagnosis of cPTC, NIFTP, and EFVPTC, were obtained from the laboratory information system. Only cases with existing fine-needle aspiration matching the tumor and available microscopic description were included. NIFTP cases with ipsilateral micro-PTC were excluded. The final cohort consisted of 59 cases (29 cPTCs and 30 NIFTP/EFVPTCs). Results:SVM successfully differentiated cPTC from NIFTP/EFVPTC 76.05 ± 0.96% of times (above chance, P \u3c 0.05) with the sensitivity of 72.6% and specificity of 81.6% in detecting cPTC. Conclusions:This machine learning algorithm was successful in distinguishing NIFTP/EFVPTC from cPTC. Our results are compatible with the prior studies, which show cytologic features are helpful in differentiating these two entities. Furthermore, this study shows the power and potential of this approach for clinical use and in developing data-driven scoring systems, which can guide cytopathology and surgical pathology diagnosis

Mean-Line Design of a Supercritical CO2 Micro Axial Turbine

Supercritical carbon dioxide (sCO 2 ) power cycles are promising candidates for concentrated-solar power and waste-heat recovery applications, having advantages of compact turbomachinery and high cycle efficiencies at heat-source temperature in the range of 400 to 800 ∘ C. However, for distributed-scale systems (0.1–1.0 MW) the choice of turbomachinery type is unclear. Radial turbines are known to be an effective machine for micro-scale applications. Alternatively, feasible single-stage axial turbine designs could be achieved allowing for better heat transfer control and improved bearing life. Thus, the aim of this study is to investigate the design of a single-stage 100 kW sCO 2 axial turbine through the identification of optimal turbine design parameters from both mechanical and aerodynamic performance perspectives. For this purpose, a preliminary design tool has been developed and refined by accounting for passage losses using loss models that are widely used for the design of turbomachinery operating with fluids such as air or steam. The designs were assessed for a turbine that runs at inlet conditions of 923 K, 170 bar, expansion ratio of 3 and shaft speeds of 150k, 200k and 250k RPM respectively. It was found that feasible single-stage designs could be achieved if the turbine is designed with a high loading coefficient and low flow coefficient. Moreover, a turbine with the lowest degree of reaction, over a specified range from 0 to 0.5, was found to achieve the highest efficiency and highest inlet rotor angles

Stress Degradation Studies on Varenicline Tartrate and Development of a Validated Stability-Indicating HPLC Method

A simple, rapid and stability-indicating reversed-phase liquid chromatographic method was developed for the assay of varenicline tartrate (VRT) in the presence of its degradation products generated from forced decomposition studies. The HPLC separation was achieved on a C18 Inertsil column (250 mm × 4.6 mm i.d. particle size is 5 μm) employing a mobile phase consisting of ammonium acetate buffer containing trifluoroacetic acid (0.02M; pH 4) and acetonitrile in gradient program mode with a flow rate of 1.0 mL min−1. The UV detector was operated at 237 nm while column temperature was maintained at 40 °C. The developed method was validated as per ICH guidelines with respect to specificity, linearity, precision, accuracy, robustness and limit of quantification. The method was found to be simple, specific, precise and accurate. Selectivity of the proposed method was validated by subjecting the stock solution of VRT to acidic, basic, photolysis, oxidative and thermal degradation. The calibration curve was found to be linear in the concentration range of 0.1–192 μg mL−1 (R2 = 0.9994). The peaks of degradation products did not interfere with that of pure VRT. The utility of the developed method was examined by analyzing the tablets containing VRT. The results of analysis were subjected to statistical analysis

Numerical Studies for Solving Fractional Riccati Differential Equation

In this paper, finite difference method (FDM) and Pade\u27-variational iteration method (Pade\u27- VIM) are successfully implemented for solving the nonlinear fractional Riccati differential equation. The fractional derivative is described in the Caputo sense. The existence and the uniqueness of the proposed problem are given. The resulting nonlinear system of algebraic equations from FDM is solved by using Newton iteration method; moreover the condition of convergence is verified. The convergence\u27s domain of the solution is improved and enlarged by Pade\u27-VIM technique. The results obtained by using FDM is compared with Pade\u27-VIM. It should be noted that the Pade\u27-VIM is preferable because it always converges to the solution even for large domain

Hypogonadism among Jordanian men with type 2 diabetes: Prevalence and associated factor

AbstractAimsPrevalence of hypogonadism is largely unknown in the general population and population of diabetics in Arab countries including Jordan. This study was conducted to determine the prevalence of hypogonadism among men with type 2 diabetes in Jordan and determine its associated factors.MethodsThis cross-sectional study included a total of 1049 consecutive men with type 2 diabetes who attended the National Center for Diabetes, Endocrinology and Genetics (NCDEG) in Amman, Jordan, in the period from August 2008 to February 2009. Data were collected from medical records and using a pre-structured questionnaire. Clinical characteristic, anthropometric measurements and laboratory measurements were obtained. Hypogonadism was defined as total testosterone <3ng/ml.ResultsOverall, 36.4% of patients with diabetes had total testosterone level <3ng/ml and 29% had symptoms of androgen deficiency. Of those with serum testosterone level <3ng/ml, 80.2% had symptoms of androgen deficiency. About 16.9% of those with serum testosterone level <3ng/ml had primary hypogonadism and 83.1% had secondary hypogonadism. Age, monthly income of less than 500JD, obesity, and neuropathy were significantly associated with low serum total testosterone level.ConclusionsThe prevalence of hypogonadism among men with type 2 diabetes in Jordan is high. This urgently calls for implementing early and universal screening programs irrespective of symptoms of androgen deficiency to detect those who have low serum total testosterone level at any early stage and to supplement testosterone accordingly

PROCEEDINGS AND PHOTO ALBUM FROM THE OFFICIAL PRESENTATION OF THE RELIGIOUS STUDIES LABORATORY (RELIGLAB) OF THE NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS

A special issue by Theophany Journal (Proceedings 1)A special issue by Theophany Journal (Proceedings 1

Hypertension Prevalence, Awareness, Treatment and Control, and Associated Factors: Results from a National Survey, Jordan

The study examined prevalence, awareness, treatment and control of hypertension (HTN), and associated factors and to evaluate the trend in hypertension between 2009 (period 2) and 1994–1998 (period 1). A national sample of 4117 adults aged 25 years and older was selected. Prevalence rate of HTN (SBP ≥ 140 or DBP ≥ 90 or on antihypertensive therapy) was 32.3% and was higher than the 29.4% prevalence rate reported in period 1. Prevalence rate was significantly higher among males, older age groups, least educated, obese, and diabetics than their counterparts. The rate of awareness among hypertensives was 56.1% and was higher than the 38.8% rate reported form period 1 data. Awareness was positively associated with age, smoking, and diabetes for both men and women, and with level of education and body mass index for men. Rate of treatment for HTN among aware patients was 63.3% and was significantly higher than the 52.8% rate reported in period1. Control rate of HTN among treated hypertensives was 39.6%; significantly higher than the 27.9% control rate in period 1. Control of HTN was positively associated with age but only for women. In conclusion, HTN is still on the rise in Jordan, and levels of awareness and control are below the optimal levels

Effect of Newtonian and non-Newtonian flow in subject specific carotid artery

Advances in the numerical simulation techniques has immensely helped in the demonstrating the importance of blood flow through elastic arteries and evaluating the disease progression and flow dynamics of cardiovascular diseases such as atherosclerosis. The present work deals with a case study of a patient diagnosed with partial narrowing of entire cervical segment of Internal Carotid Artery (ICA), while Common Carotid Artery (CCA) and External Carotid Artery (ECA) appears to be normal. Subject specific 3D carotid bifurcation CAD model is generated based on CT-angio scan data using MIMICS-14.0 and numerical analysis is performed using Computational Fluid Dynamics (CFD) in ANSYS-CFX-14.0. Pulsatile blood flow through the subject-specific artery is investigated to study the influence of rheology on the haemodynamics in the blood flow. The simulation results obtained through Carreau-Yasuda and Newtonian models are investigated. Flow behaviour observed during peak systole exhibits significant difference in the spatial parameters between both the Newtonian and nonNewtonians models. The comparison of local shear stress magnitude in CCA, ICA and ECA demonstrates that WSS is highly influenced by the shear thinning property of blood. This variation is also observed artery branches with reduced lumen diameter, lumen narrowing due to stenosis and in the bifurcation zone

High prevalence of current tobacco smoking among patients with tuberculosis and people living with HIV in Jordan: A cross-sectional survey

INTRODUCTION Continued smoking by patients with tuberculosis (TB) and people living with HIV (PLHIV) leads to adverse treatment outcomes. Estimates of tobacco use among the population are scarce in the Eastern Mediterranean region, where the burden of TB and HIV is also low but highly variable. This study determined the prevalence of current smoking and assessed factors associated with current smoking among patients with TB and PLHIV in Jordan. METHODS We analyzed data from the Jordan Knowledge, Attitude, and Practices survey in 2021. Information on current tobacco use, including products and frequency of smoking, was collected from 452 patients with TB and 152 PLHIV. We performed multivariable logistic regression to assess the sociodemographic characteristics independently associated with current smoking.RESULTS Prevalence of current smoking was 43.8% among TB patients and 67.8 % among PLHIV, and conventional cigarettes were the most used tobacco products. The prevalence of current smoking among patients with TB was higher among males (AOR=8.20; 95% CI: 5.05-13.32), Jordanians (AOR=5.37; 95% CI: 2.66- 10.86) and Syrians (AOR=4.13; 95% CI: 1.60-10.67), and those experiencing financial difficulties (AOR=2.83; 95% CI: 1.69-4.74). The prevalence of current smoking among PLHIV was higher in those with financial difficulties (AOR=3.13; 95% CI: 1.19-8.27). CONCLUSIONS Nearly half of the patients with TB and PLHIV were current tobacco smokers, higher than the general population. There is an urgent need to investigate the reasons for such a high smoking prevalence and introduce and strengthen smoking cessation services under the TB and HIV control programs