Dropout and Engineering undergraduate programs at the Universidad Nacional de Colombia between 2012-2019

[EN] Dropout is a topic of significant concern to Higher Education Institutions, especially in Colombia it is considered one of the most important indicators to define higher education quality. Nevertheless, in Colombia, and particularly at the Universidad Nacional de Colombia, it has been generally assessed only academic dropout. This decision has prevented understanding other types of dropouts that also occur in the university. The research group performed Multiple Correspondence Analysis to assess the relationship between dropout types (academic, dropout on request, and expiry of time limits) and variables such as sex, socioeconomic stratum, type of admission, and semester of dropout. In the results, we found a disparity between types of dropout concerning the type of university admission, sex, socio-economic stratum, and the semester in which dropout occurs. Women are related to the dropout request while men are associated with the academic dropout. Additionally, the academic dropout occurs in the first 4 semesters, and the expiry of time limits occurs in the last ones.Sánchez-Nítola, M.; Grijalba, DM.; Embus, M.; Suarez, A.; Guevara Montoya, J. (2020). Dropout and Engineering undergraduate programs at the Universidad Nacional de Colombia between 2012-2019. En 6th International Conference on Higher Education Advances (HEAd'20). Editorial Universitat Politècnica de València. (30-05-2020):1331-1337. https://doi.org/10.4995/HEAd20.2020.11270OCS1331133730-05-202

Comparative Pathogenicity of Lomentospora prolificans (Scedosporium prolificans) Isolates from Mexican Patients

We identified 11 Lomentospora prolificans isolates recovered from Mexican patients using phenotypic and molecular characteristics. The identification of isolates was assessed by internal transcribed spacer (ITS rDNA) sequencing. In vitro susceptibility to amphotericin B, fluconazole, voriconazole, posaconazole, caspofungin, anidulafungin and micafungin was determined according to Clinical and Laboratory Standards Institute (CLSI) procedures. Three isolates (07-2239, 11-2242 and 04-2673) were used to induce systemic infection in immunocompetent ICR mice. Survival and tissue burden studies were used as markers of pathogenicity. All of the strains were resistant to every antifungal tested with MIC’s for AmB (8–[8 lg/ml), VRC (16–[16 lg/ml), PSC (16– [16 lg/ml), FLC (64–[64 lg/ml) and echinocandins with MICs C8 lg/ml. One hundred, ninety and sixty percent of the infected mice with the strains 07-2239, 11-2242 and 04-2673 died during the study, respectively. Regarding tissue burden, the highest fungal load of the infected mice was detected in brain followed by spleen and kidney, regardless of the strain

Influencia del riego deficitario controlado precosecha sobre la calidad de la cereza ´Prime Giant`

El uso de redes de sensores para el manejo del riego deficitario controlado (RDC) en cerezo puede incidir en la mejora de la productividad del agua, calidad de la fruta y en su comportamiento poscosecha, al permitir el conocimiento y control del estado hídrico del suelo y árbol en todo momento. En el primer año de ensayo, el riego deficitario aplicado en precosecha para satisfacer el 85% de las necesidades máximas del cultivo (ETcg) permitió un ahorro de agua del 17% (380 m3 ha-1) respecto al tratamiento control, que se regó al 110% de la ETcg. Este déficit hídrico ligero no afectó a la producción (16,13 t ha-1) e incluso mejoró la calidad del fruto. Así, en el momento de la cosecha (t0) los frutos bajo déficit ligero presentaron matices más rojos y mayor acidez que los de riego completo. Esta mayor acidez no afectó al índice de madurez debido a la compensación por sólidos solubles totales (SST). El carácter de mayor acidez perduró tras 30 días de conservación en frio (t1) y 5 días de simulación de las condiciones de comercialización (t2). Igualmente, los frutos bajo déficit hídrico presentaron una tendencia a menores pérdidas de peso por deshidratación a finales de los periodos de conservación en frio y de simulación de la comercialización.Ministerio de Economía y Competitividad AGL2013-49047-C2-1

DNA delivery via cationic solid lipid nanoparticles (SLNs)

In recent years the use of solid lipid nanoparticles (SLNs) as transport systems for the delivery of drugs and biomolecules has become particularly important. The use of cationic SLNs developed by the technique of microemulsion, which are complexed with DNA in order to study their application as non-viral vectors in gene therapy, is reported. The nanoparticles are characterized by scanning electron microscopy and transmission electron microscopy (SEM and TEM), atomic force microscopy (AFM) and differential scanning calorimetry (DSC). Furthermore, the process of lyophilization of the samples and their stability was studied. The nanoparticles obtained presented a particle size of 340 nm with a positive surface charge of 44 mV and the capability of forming lipoplexes with DNA plasmids was stated

The concept of death in children aged from 9 to 11 years: Evidences through inductive and deductive analysis of drawings

The objective of the research was to analyze children’s conceptualization of death through drawings, using a mixed approach, which combines deductive and inductive qualitative analysis. The sample consisted of 99 children aged 9–11 years, who were asked to elaborate a drawing about their idea of death and to explain it to the researchers. Drawings were coded basing on Tamm and Granqvist’s model (deductive analysis) and codes and categories were created and modified (inductive analysis). Three main categories were identified in the analysis and four sub-categories were modified and/or created: causes of death, good death, anxiety-fear and symbolization

Suicide attempts in mexican teenagers: a cultural consensus theory perspective

El suicidio es un problema de salud pública mundial y los adolescentes son los que presentan con mayor frecuencia esta problemática. El estudio realizado identifica la estructura semántica del dominio cultural, el promedio de conocimiento y el grado de consenso cultural que sobre el suicidio tienen adolescentes con tentativa suicida. El trabajo es un estudio cualitativo mediante la técnica de listas libres. Participaron 29 adolescentes (13 a 18 años). Las listas libres fueron sobre: las causas; los signos y los síntomas; lo que siente, piensa y hace un adolescente antes de cometer suicidio y las estrategias de prevención de éste. Los resultados muestran para cada pregunta un único modelo semántico en el dominio cultural. En lo estructural se identifican los problemas familiares como la causa del intento suicida; la depresión y la tristeza son síntomas previos al intento suicida. La tristeza y la soledad, salir del problema y suicidarse es lo que considera que siente, piensa y hace un adolescente previo al intento de suicidio. Como estrategias de prevención, se identifican le ponga más atención y hablar con él. Los resultados ponderan la importancia de la familia para los programas de prevención de las conductas suicidas en adolescentes. The suicide is a problem of public world health and the adolescents are those who present with more frequency this problem. Nevertheless, the studies of the suicide phenomenon from a cultural perspective are limited. Cultural research in suicidology is important to develop the understanding of the meanings of suicidal behavior in different contexts. The cultural consensus theory would contribute to the cultural perspective of the knowledge of suicidal behaviors in terms of its internal elements and their functioning (emic) and this theory allows knowing if there exists a knowledge shared by a social group regarding an issue and allows to recognize its organization. The aim of this study was to identify the semantic structure of the cultural domain, as well as the average of knowledge and the degree of cultural consensus regarding suicide among adolescent suicide attempters. It was a qualitative study, using the free-listing technique, with a non-random sample made up of 29 adolescents between the ages of 13 and 18 years. The free lists were on: the causes; the signs and the symptoms; what he/she feels, thinks and does before attempting suicide and the strategies of suicide prevention at adolescence. The results showed for every question a single semantic model in the cultural domain suicide attempt. In such structure, the family problems were identified as the cause of suicidal attempt; the depression and the sadness were symptoms before suicidal attempt. The sadness, the loneliness and the anger were what an adolescent feels before the suicide attempt. Furthermore, to get out of the problem and to end his/her life were what an adolescent thinks before attempting suicide and to commit suicide was what an adolescent does before to suicide attempt. To pay more attention, to talk with the adolescent, to improve the communication with the parents and to attend a psychotherapy were identified as strategies for suicide prevention. The results highlight the importance of the family of suicide prevention programs for adolescents based on cultural knowledge.ITESO, A.C.Universidad de GuadalajaraInstituto Mexicano del Seguro SocialPsicólogos Especializados Jalisc

Origin, accumulation and fate of dissolved organic matter in an extreme hypersaline shallow lake

Hypersaline endorheic aquatic systems (H-SEAS) are lakes/shallow playas in arid and semiarid regions that undergo extreme oscillations in salinity and severe drought episodes. Although their geochemical uniqueness and microbiome have been deeply studied, very little is known about the availability and quality of dissolved organic matter (DOM) in the water column. A H-SEAS from the Monegros Desert (Zaragoza, NE Spain) was studied during a hydrological wetting-drying-rewetting cycle. DOM analysis included: (i) a dissolved organic carbon (DOC) mass balance; (ii) spectroscopy (absorbance and fluorescence) and (iii) a molecular characterization with Fourier-transform ion cyclotron resonance mass spectrometry (FT-ICR-MS). The studied system stored a large amount of DOC and under the highest salinity conditions, salt-saturated waters (i.e., brines with salinity > 30%) accumulated a disproportionate quantity of DOC, indicating a significant in-situ net DOM production. Simultaneously, during the hydrological transition from wet to dry, the DOM pool showed strong alterations of it molecular composition. Spectroscopic methods indicated that aromatic and degraded DOM was rapidly replaced by fresher, relatively small, microbial-derived moieties with a large C/N ratio. FT-ICR-MS highlighted the accumulation of small, saturated and oxidized molecules (molecular O/C > 0.5), with a remarkable increase in the relative contribution of highly oxygenated (molecular O/C > 0.9) compounds and a decrease of aliphatic and carboxyl-rich alicyclic moleculesThese results indicated that H-SEAS are extremely active in accumulating and processing DOM, with the notable release of organic solutes probably originated from decaying microplankton under large osmotic stress at extremely high salinitie

Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes

Ezrin, radixin, and moesin (ERM) regulate cortical morphogenesis and cell adhesion by connecting membrane adhesion receptors to the actin-based cytoskeleton. We have studied the interaction of moesin and ezrin with the vascular cell adhesion molecule (VCAM)-1 during leukocyte adhesion and transendothelial migration (TEM). VCAM-1 interacted directly with moesin and ezrin in vitro, and all of these molecules colocalized at the apical surface of endothelium. Dynamic assessment of this interaction in living cells showed that both VCAM-1 and moesin were involved in lymphoblast adhesion and spreading on the endothelium, whereas only moesin participated in TEM, following the same distribution pattern as ICAM-1. During leukocyte adhesion in static or under flow conditions, VCAM-1, ICAM-1, and activated moesin and ezrin clustered in an endothelial actin-rich docking structure that anchored and partially embraced the leukocyte containing other cytoskeletal components such as α-actinin, vinculin, and VASP. Phosphoinositides and the Rho/p160 ROCK pathway, which participate in the activation of ERM proteins, were involved in the generation and maintenance of the anchoring structure. These results provide the first characterization of an endothelial docking structure that plays a key role in the firm adhesion of leukocytes to the endothelium during inflammation

Del contexto cultural al funcionamiento familiar. Conocimientos compartidos y relaciones familiares en adolescentes con intento de suicidio

El objetivo de este texto es identificar y comparar la estructura semántica del dominio cultural, el conocimiento promedio y el grado de consenso cultural sobre las causas del intento de suicidio, los síntomas previos y las estrategias de prevención del intento de suicidio, además evaluar el funcionamiento familiar entre adolescentes mexicanos con y sin intento de suicidio. Se presenta un estudio mixto metodológicamente que usa la técnica de listas libres y el inventario de recursos familiares en una muestra propositiva de 65 adolescentes (13 a 18 años) divididos en dos grupos: el grupo de adolescentes con tentativa suicida y un grupo control con adolescentes estudiantes sin antecedentes de conductas suicidas. Los problemas familiares fueron la principal causa del intento suicida, mientras que la depresión y la tristeza fueron síntomas previos a una tentativa suicida en ambos grupos. La ayuda psicológica y el desarrollo de habilidades de escucha en los padres fueron señaladas como las estrategias para la prevención del suicidio. Respecto del funcionamiento familiar, los adolescentes con tentativa suicida percibieron más conflictos familiares y menor comunicación y apoyo en sus familias en comparación con el grupo control. Los resultados sugieren un conocimiento compartido culturalmente sobre las causas, los síntomas y las estrategias de prevención del intento de suicidio en los adolescentes, el cual se confirma en la percepción del funcionamiento familiar. La familia, elemento central en la cultura mexicana, debe ser considerada en las estrategias de prevención del intento de suicidio en los adolescentes en México. AIM: The aim of the study was to identify and to compare the semantic structure of the cultural domain, the average knowledge and the degree of cultural consensus regarding knowledge of suicide attempts cause, symptoms and prevention strategies to suicide attempt and the family functioning among Mexican adolescents with and without previous suicide attempt. Method: It was a mixed study, using the free-listing technique and an inventory of family resources, with a non-random sample of 65 adolescents (13-18 years) divided in two groups. The suicide attempters group and the control group were high school students, without a history of suicide behaviors. Results: Family problems were identified as the most important cause of suicide attempts in both groups, while depression and sadness were identified as symptoms prior to the suicide attempt in both groups. Psychological aid and development of listening skills in the parents were the most frequent responses regarding prevention strategies to suicide attempt. Regarding family functioning teenage suicide attempters showed more family conflict, less family communication and support than teenage non suicide attempters. Conclusions: The results suggest a same cultural knowledge background regarding causes, symptoms prior and prevention strategies to suicide attempt in Mexican adolescents. Mexican culture centered in family relationships is important to be considered in design of prevention strategies to suicide attempt in adolescence in Mexico.ITESO, A.C