450 research outputs found
Spontaneous splenic rupture and Anisakis appendicitis presenting as abdominal pain: a case report
First-line treatment in lymphomatoid papulosis: a retrospective multicentre study
Background: Data regarding response to treatment in lymphomatoid papulosis (LyP) are scarce. Aim: To assess the daily clinical practice approach to LyP and the response to first-line treatments. Methods: This was a retrospective study enrolling 252 patients with LyP. Results: Topical steroids, methotrexate and phototherapy were the most common first-line treatments, prescribed for 35%, 20% and 14% of the patients, respectively. Complete response (CR) was achieved in 48% of treated patients. Eczematous lesions significantly increased relative risk (RR) of not achieving CR (RR = 1.76; 95% CI 1.16-2.11). Overall median time to CR was 10 months (95% CI 6-13 months), and 78% of complete responders showed cutaneous relapse; both results were similar for all treatment groups (P > 0.05). Overall estimated median disease-free survival (DFS) was 11 months (95% CI 9-13 months) but DFS for patients treated with phototherapy was 23 months (95% CI 10-36 months; P < 0.03). Having the Type A LyP variant (RR = 2.04; 95% CI 0.96-4.30) and receiving a first-line treatment other than phototherapy (RR = 5.33; 95% CI 0.84-33.89) were significantly associated with cutaneous early relapse. Of the 252 patients, 31 (13%) had associated mycosis fungoides unrelated to therapeutic approach, type of LyP or T-cell receptor clonality. Conclusions: Current epidemiological, clinical and pathological data support previous results. Topical steroids, phototherapy and methotrexate are the most frequently prescribed first-line treatments. Although CR and cutaneous relapse rates do not differ between them, phototherapy achieves a longer DFS. Presence of Type A LyP and use of topical steroid or methotrexate were associated with an increased risk of early relapse
Measurements of differential cross sections of Z/gamma*+jets+X events in proton anti-proton collisions at sqrt{s}=1.96 TeV
We present cross section measurements for Z/gamma*+jets+X production,
differential in the transverse momenta of the three leading jets. The data
sample was collected with the D0 detector at the Fermilab Tevatron proton
anti-proton collider at a center-of-mass energy of 1.96 TeV and corresponds to
an integrated luminosity of 1 fb-1. Leading and next-to-leading order
perturbative QCD predictions are compared with the measurements, and agreement
is found within the theoretical and experimental uncertainties. We also make
comparisons with the predictions of four event generators. Two
parton-shower-based generators show significant shape and normalization
differences with respect to the data. In contrast, two generators combining
tree-level matrix elements with a parton shower give a reasonable description
of the the shapes observed in data, but the predicted normalizations show
significant differences with respect to the data, reflecting large scale
uncertainties. For specific choices of scales, the normalizations for either
generator can be made to agree with the measurements.Comment: Published in PLB. 11 pages, 3 figure
Search for resonant diphoton production with the D0 detector
We present a search for a narrow resonance in the inclusive diphoton final
state using 2.7 fb-1 of data collected with the D0 detector at the Fermilab
Tevatron ppbar Collider. We observe good agreement between the data and the
background prediction, and set the first 95% C.L. upper limits on the
production cross section times the branching ratio for decay into a pair of
photons for resonance masses between 100 and 150 GeV. This search is also
interpreted in the context of several models of electroweak symmetry breaking
with a Higgs boson decaying into two photons.Comment: 7 pages, 3 figures
Search for charged Higgs bosons decaying to top and bottom quarks in ppbar collisions
We describe a search for production of a charged Higgs boson, q \bar{q'} ->
H^+, reconstructed in the t\bar{b} final state in the mass range 180 <= M_{H^+}
<= 300 GeV. The search was undertaken at the Fermilab Tevatron collider with a
center-of-mass energy sqrt{s} = 1.96 TeV and uses 0.9 fb^{-1} of data collected
with the D0 detector. We find no evidence for charged Higgs boson production
and set upper limits on the production cross section in the Types I, II and III
two-Higgs-doublet models (2HDMs). An excluded region in the (M_{H^+},tan\beta)
plane for Type I 2HDM is presented.Comment: Submitted to Phys. Rev. Letter
Search for right-handed W bosons in top quark decay
We present a measurement of the fraction f+ of right-handed W bosons produced
in top quark decays, based on a candidate sample of events in the
lepton+jets decay mode. These data correspond to an integrated luminosity of
230pb^-1, collected by the DO detector at the Fermilab Tevatron
Collider at sqrt(s)=1.96 TeV. We use a constrained fit to reconstruct the
kinematics of the and decay products, which allows for the
measurement of the leptonic decay angle for each event. By comparing
the distribution from the data with those for the expected
background and signal for various values of f+, we find
f+=0.00+-0.13(stat)+-0.07(syst). This measurement is consistent with the
standard model prediction of f+=3.6x10^-4.Comment: Submitted to Physical Review D Rapid Communications 7 pages, 3
figure
Measurement of the t-channel single top quark production cross section
The D0 collaboration reports direct evidence for electroweak production of
single top quarks through the t-channel exchange of a virtual W boson. This is
the first analysis to isolate an individual single top quark production
channel. We select events containing an isolated electron or muon, missing
transverse energy, and two, three or four jets from 2.3 fb^-1 of ppbar
collisions at the Fermilab Tevatron Collider. One or two of the jets are
identified as containing a b hadron. We combine three multivariate techniques
optimized for the t-channel process to measure the t- and s-channel cross
sections simultaneously. We measure cross sections of 3.14 +0.94 -0.80 pb for
the t-channel and 1.05 +-0.81 pb for the s-channel. The measured t-channel
result is found to have a significance of 4.8 standard deviations and is
consistent with the standard model prediction.Comment: 7 pages, 6 figure
Search for scalar leptoquarks and T-odd quarks in the acoplanar jet topology using 2.5 fb-1 of ppbar collision data at sqrt(s)=1.96 TeV
A search for new physics in the acoplanar jet topology has been performed in
2.5 fb-1 of data from ppbar collisions at sqrt(s)=1.96 TeV, recorded by the D0
detector at the Fermilab Tevatron Collider. The numbers of events with exactly
two acoplanar jets and missing transverse energy are in good agreement with the
standard model expectations. The result of this search has been used to set a
lower mass limit of 205 GeV at the 95% C.L. on the mass of a scalar leptoquark
when this particle decays exclusively into a quark and a neutrino. In the
framework of the Little Higgs model with T-parity, limits have also been
obtained on the T-odd quark mass as a function of the T-odd photon mass
Observation of ZZ production in ppbar collisions at sqrt(s) = 1.96 TeV
We present an observation for ZZ -> l+l-l'+l'- (l, l' = e or mu) production
in ppbar collisions at a center-of-mass energy of sqrt(s) = 1.96 TeV. Using 1.7
fb-1 of data collected by the D0 experiment at the Fermilab Tevatron Collider,
we observe three candidate events with an expected background of 0.14 +0.03
-0.02 events. The significance of this observation is 5.3 standard deviations.
The combination of D0 results in this channel, as well as in ZZ -> l+l-nunubar,
yields a significance of 5.7 standard deviations and a combined cross section
of sigma(ZZ) = 1.60 +/- 0.63 (stat.) +0.16 -0.17 (syst.) pb.Comment: 7 pages, 1 figure, 2 tables Modified slightly following review
proces
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