Characterization of Gαq-coupled receptor signalling via the novel effector PKCζ

Tesis doctoral inédita, leída en la Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Biología Molecular. Fecha de lectura: 15-03-201

La cosmovisión de la transición española en la película Juana la loca… de ve z en cuando un manual para la comprensión de la come día histórica de los ochenta

Although it was one of the great movie blockbusters of the time, Joan the Mad... once in a while (José Ramón Larraz, 1983), received harsh criticism from the specialized public, who saw in the film a painful way of making movies. Characters, ambience, script, interpretations, etc., nothing escaped the pen of the critics, who vented their criticism on it. Even so, the public connected perfectly with it, not in vain, the Court of the Catholic Kings came to make the distant Spanish transition their own. Through the following research, we want to value this important contribution of Spanish cinema, as a document that perfectly reflects the political, social, cultural and artistic life of the Spanish Transition, offering a compendium that allows us to understand the thoroughness and intellectuality of the script in all its complexity.Aunque fue uno de los grandes taquillazos cinematográficos de la época, Juana la Loca… de vez en cuando (José Ramón Larraz, 1983), recibió unas duras críticas por parte del público especializado, que veían en la cinta una penosa manera de hacer cine. Personajes, ambientación, guion, interpretaciones, etc., nada escapó a la pluma de los críticos, que se cebaron duramente con ella. Aun así, el público conectó a la perfección con ella, no en vano, la Corte de los Reyes Católicos vino a hacer suya la lejana Transición española. Mediante la siguiente investigación, queremos poner en valor esta importante aportación del cine español, como un documento que refleja a la perfección la vida política, social, cultural y artística de la Transición española, ofreciendo un compendio que permita comprender la minuciosidad e intelectualidad del guion en toda su complejidad

Nonequilibrium Processes in Supersonic Jets of N2, H2, and N2 + H2 Mixtures: (I) Zone of Silence

7 pages, 5 figures, 1 table.-- Printed version published Jul 30, 2009.Supporting information available at: http://pubs.acs.org/doi/suppl/10.1021/jp901700cNumber density and rotational temperature in the zone of silence of supersonic jets of N2, H2, and their mixtures N2 + 2H2 and 2N2 + H2, at p0 = 1 bar and T0 = 295 K, have been measured by Raman spectroscopy. Translational temperature in the jets has been derived from the experimental data assuming isentropic flow. The density along the jet axis decays at a rate depending on the composition of the expanded gas, which can be explained by the variation of its effective heat capacity ratio. Measurements across the jet axis do not support numerical off-axis density modeling from the literature. A strong nonequilibrium between the rotational degrees of freedom of both species is observed, even between the two spin species ortho-H2 and para-H2. From the corresponding rotational temperature data, a relationship between rotational cross sections for the inelastic collisions of the different species is established. In the expansions of the mixtures, an enrichment of N2 is measured on the axis, which is compared with the predictions from the theory of diffusive separation in jets.A. Ramos acknowledges CSIC for an I3P grant. This work has been supported by the Spanish Ministerio de Educación y Ciencia, research Project No. FIS2004-02576 and Project No. FIS2007-61430, and by the Comunidad de Madrid, Project No. S-0505/ESP /0237(ASTROCAM).Peer reviewe

Quantitative study of cluster growth in free-jet expansions of CO2 by Rayleigh and Raman scattering

The condensation produced in supersonic expansions of CO2 is studied quantitatively combining Rayleigh and Raman scattering. The cluster number density nc and the mean cluster size are obtained for five expansions with stagnation pressures P0=1-5 bars, and temperature T0=294 K, along axial and radial directions; nc and are determined from the condensation onset up to a terminal size, verifying the empirical law prop.P0^(2.23). A maximum growth rate d/dt approx.8x10(8) s^(-1) is estimated for the 5-bar expansion. The Raman spectra show a coexistence of solid and liquidlike phases in the jet, with a progressive transition from the liquid to the solid fraction as the clusters increase their size.Ministerio de Educación y Ciencia, Proyectos BFM2001-2276 y FIS2004-02576Peer reviewe

The iconography of Jesus gathering his clothes and his diffusion in Latin America: approximation and prospects for research on the subject

El presente trabajo tiene como objetivo dar a conocer aquellos testimonios gráficos relacionados con la iconografía de Jesús recogiendo sus vestiduras después de la flagelación conservados en diversos puntos de la geografía sudamericana. El modelo original, de procedencia europea, llegó a países como Colombia, México o Guatemala entre otros, a través de Andalucía y de los modelos que aquí se estaban realizando en las áreas de Sevilla, Antequera y Granada.This paper aims to present those graphic testimonials related to the iconography of Jesus gathering his clothes after the Flagellation conserved at different locations in Latin America. The original model, which came from Europe, reached countries such as Colombia, Mexico and Guatemala, through Andalusia and the models that were circulating in the areas of Seville, Antequera and Granada

From the chronicle to journalism, sources for the construction of the illustrated holy week

En el presente trabajo se pretende dar una visión de las celebraciones de la Semana Santa de Valladolid, y de sus celebrados conjuntos procesionales. No se pretende dar una simple visión histórica de esta celebración en el siglo XVIII, si no trazar que pensaban los contemporáneos de ese siglo de este potencial, cultural, artístico y antropológico que suponía la celebración a través de sus escritos. Es de destacar que tan singular fenómeno no se ciñó a las fronteras de la ciudad sino que fue un tema en consideración para la historiografía de ámbito nacional, por lo que recogemos tanto fuentes locales como nacionales, en un siglo el XVIII, que pasaremos de una mentalidad tardo barroca a una plenamente ilustrada, cambio que en ocasiones se desarrolló de manera traumática, pensamientos encontrados que quedaron marcados en maneras distintas de narrar, desde la historia pre científica hasta la crónica periodística. De manera específica se han analizado y comparado tres fuentes de información coetáneas a la época, una de ellas el primer diario publicado en Valladolid. Las fuentes utilizada son las siguientes: El Diario de Valladolid fue redactado por Ventura Pérez entre 1720 y 1784; la Historia Secular y Eclesiástica de la muy Antigua, Augusta, Coronada, muy Ilustre, muy Noble, Rica y muy Leal Ciudad de Valladolid, escrita por Manuel Canesi Acevedo (1681-1750) y el Diario Pinciano, primer periódico de Valladolid, obra de José Mariano Beristáin, cuyo primer número se editó el 7 de febrero de 1787, siendo el primer periódico de Valladolid. Se ha realizado un vaciado de estas fuentes, cuya base es la justificación documental del presente trabajo.In the present study we intend to offer a general understanding about the Holy Week (Easter) in Valladolid and its famous processional ensembles with different sources. We are not offering a simple historic view on this celebration in the 18th century, but showing what the people in those days thought about the celebration (and its cultural, artistic and anthropological importance) as is reflected in their writing. The Holy Week in Valladolid was an important theme in historiography on a national level, hence we gather here both local and national sources from a time in which people went from a late Baroque mentality to a fully Enlightened (Age of Enlightenment) one. This change was sometimes traumatic, and these conflicting thoughts can be appreciated in the different ways of narrating, from pre-scientific history to journalistic chronicle. Specifically, three sources of information have been analyzed and compared to the time, one of them the first newspaper published in Valladolid. The sources used are the following: El Diario de Valladolid was written by Ventura Pérez between 1720 and 1784; the Secular and Ecclesiastical History of the very Ancient, Augusta, Coronada, very Illustrious, very Noble, Rich and Very Loyal City of Valladolid, written by Manuel Canesi Acevedo (1681-1750) and the Diario Pinciano, first newspaper of Valladolid, work of José Mariano Beristáin, whose first issue was published on February 7, 1787, being the first newspaper of Valladolid. There has been a voiding of these sources, whose basis is the documentary justification of this work

Procesional “trespassers”: non-mormative iconographies in spanish Holy Week in the early modernRUBÉN

In this article we will study the presence of those hagiographic images whose iconography places them outside of the Cycle of the Passion of Christ, in Spanish penitential processions throughout history. We will take a closer look at the ones that preside on a processional float alone by its own merits.En este trabajo estudiaremos la presencia de imágenes hagiográficas que se pueden considerar ajenas al ciclo de la Pasión de Cristo en las procesiones penitenciales españolas a lo largo de la historia, deteniéndonos fundamentalmente en aquellas que por méritos propios han sido merecedores de presidir un paso procesional en solitario.Proyecto En los orígenes de la integración y el conflicto en sociedades multiculturales de Europa y el Mediterráneo, dentro de la convocatoria de ayudas en concurrencia competitiva a proyectos de I+D+i en el marco del Programa Operativo FEDER Andalucía 2014-2020. Referencia: UMA20-FEDERJA-02

Al principio fue… Jesús recogiendo sus vestiduras y sus fuentes literarias de inspiración

The iconography of “Christ gathering his clothes” after the Flagellation is considered often a strange subject in the visual context of the Passion. This article studies literary and iconographical sources of this episode, before and after The Catholic ReformHasta ahora el tema que nos ocupa, el de Jesús recogiendo sus vestiduras después de la flagelación, había partido de la consideración de su rareza dentro de la iconografía religiosa y de su carácter especialmente atípico en lo que se refiere a la imaginería pasionista. Se pretende aquí establecer las relaciones iconográficas entre el modelo de estudio y aquellas fuentes literarias que lo inspiraron a lo largo de de los siglos, con el objetivo de ampliar su margen de producción mas allá de los límites de la Contrarreforma, y romper con la tradicional idea de Cristo recogiendo sus vestiduras versus barroc

Experimental and theoretical determination of rotational-translational state-to-state rate constants for N2:He collisions at low temperature (3<T<20 K)

10 pages, 7 figures.-- PACS nr.: 34.50.Fa.We present an experimental determination of state-to-state rotational–translational (RT) rate constants of N2:He collisions in the vibrational ground state as a function of temperature in the range 3<T<20 K. Raman spectroscopy in supersonic expansions of N2/He mixtures is used to determine the primary data that, together with the N2:N2 state-to-state RT rates previously determined [Ramos et al., Phys. Rev. A 66, 022702 (2002)], are needed to solve the master equation according to a procedure that does not impose any particular scaling law. We also report first principle calculations of the N2:He state-to-state RT rate constants performed using the full three-dimensional potential energy surface of Reid et al. [J. Chem. Phys. 107, 2329 (1997)], in the 3<T<300 K temperature range. The coupled-channel method, and the coupled-states approximation, were applied in the low (0–610 cm–1) and in the high (610–1500 cm–1) energy limits, respectively. A good agreement between theoretical and experimental results is found in the temperature range where comparison is possible.Thanks are due to the Spanish MCYT for financial support of the experimental part of this work (Research Project No. BFM2001-2276).Peer reviewe