The Photoeccentric Effect and Proto-Hot Jupiters II. KOI-1474.01, a candidate eccentric planet perturbed by an unseen companion

The exoplanets known as hot Jupiters---Jupiter-sized planets with periods less than 10 days---likely are relics of dynamical processes that shape all planetary system architectures. Socrates et al. (2012) argued that high eccentricity migration (HEM) mechanisms proposed for situating these close-in planets should produce an observable population of highly eccentric proto-hot Jupiters that have not yet tidally circularized. HEM should also create failed-hot Jupiters, with periapses just beyond the influence of fast circularization. Using the technique we previously presented for measuring eccentricities from photometry (the "photoeccentric effect"), we are distilling a collection of eccentric proto- and failed-hot Jupiters from the Kepler Objects of Interest (KOI). Here we present the first, KOI-1474.01, which has a long orbital period (69.7340 days) and a large eccentricity e = 0.81+0.10/-0.07, skirting the proto-hot Jupiter boundary. Combining Kepler photometry, ground-based spectroscopy, and stellar evolution models, we characterize host KOI-1474 as a rapidly-rotating F-star. Statistical arguments reveal that the transiting candidate has a low false-positive probability of 3.1%. KOI-1474.01 also exhibits transit timing variations of order an hour. We explore characteristics of the third-body perturber, which is possibly the "smoking-gun" cause of KOI-1474.01's large eccentricity. Using the host-star's rotation period, radius, and projected rotational velocity, we find KOI-1474.01's orbit is marginally consistent with aligned with the stellar spin axis, although a reanalysis is warranted with future additional data. Finally, we discuss how the number and existence of proto-hot Jupiters will not only demonstrate that hot Jupiters migrate via HEM, but also shed light on the typical timescale for the mechanism.Comment: ApJ, in press. Received 2012 July 7; accepted 2012 October 1

A super-Earth transiting a nearby low-mass star

A decade ago, the detection of the first transiting extrasolar planet provided a direct constraint on its composition and opened the door to spectroscopic investigations of extrasolar planetary atmospheres. As such characterization studies are feasible only for transiting systems that are both nearby and for which the planet-to-star radius ratio is relatively large, nearby small stars have been surveyed intensively. Doppler studies and microlensing have uncovered a population of planets with minimum masses of 1.9-10 times the Earth's mass (M_Earth), called super-Earths. The first constraint on the bulk composition of this novel class of planets was afforded by CoRoT-7b, but the distance and size of its star preclude atmospheric studies in the foreseeable future. Here we report observations of the transiting planet GJ 1214b, which has a mass of 6.55 M_Earth and a radius 2.68 times Earth's radius (R_Earth), indicating that it is intermediate in stature between Earth and the ice giants of the Solar System. We find that the planetary mass and radius are consistent with a composition of primarily water enshrouded by a hydrogen-helium envelope that is only 0.05% of the mass of the planet. The atmosphere is probably escaping hydrodynamically, indicating that it has undergone significant evolution during its history. As the star is small and only 13 parsecs away, the planetary atmosphere is amenable to study with current observatories.Comment: 13 pages, 3 figures, published in Natur

EPG5-related Vici syndrome: a paradigm of neurodevelopmental disorders with defective autophagy

Vici syndrome is a progressive neurodevelopmental multisystem disorder due to recessive mutations in the key autophagy gene EPG5. We report genetic, clinical, neuroradiological, and neuropathological features of 50 children from 30 families, as well as the neuronal phenotype of EPG5 knock-down in Drosophila melanogaster. We identified 39 different EPG5 mutations, most of them truncating and predicted to result in reduced EPG5 protein. Most mutations were private, but three recurrent mutations (p.Met2242Cysfs*5, p.Arg417*, and p.Gln336Arg) indicated possible founder effects. Presentation was mainly neonatal, with marked hypotonia and feeding difficulties. In addition to the five principal features (callosal agenesis, cataracts, hypopigmentation, cardiomyopathy, and immune dysfunction), we identified three equally consistent features (profound developmental delay, progressive microcephaly, and failure to thrive). The manifestation of all eight of these features has a specificity of 97%, and a sensitivity of 89% for the presence of an EPG5 mutation and will allow informed decisions about genetic testing. Clinical progression was relentless and many children died in infancy. Survival analysis demonstrated a median survival time of 24 months (95% confidence interval 0–49 months), with only a 10th of patients surviving to 5 years of age. Survival outcomes were significantly better in patients with compound heterozygous mutations (P = 0.046), as well as in patients with the recurrent p.Gln336Arg mutation. Acquired microcephaly and regression of skills in long-term survivors suggests a neurodegenerative component superimposed on the principal neurodevelopmental defect. Two-thirds of patients had a severe seizure disorder, placing EPG5 within the rapidly expanding group of genes associated with early-onset epileptic encephalopathies. Consistent neuroradiological features comprised structural abnormalities, in particular callosal agenesis and pontine hypoplasia, delayed myelination and, less frequently, thalamic signal intensity changes evolving over time. Typical muscle biopsy features included fibre size variability, central/internal nuclei, abnormal glycogen storage, presence of autophagic vacuoles and secondary mitochondrial abnormalities. Nerve biopsy performed in one case revealed subtotal absence of myelinated axons. Post-mortem examinations in three patients confirmed neurodevelopmental and neurodegenerative features and multisystem involvement. Finally, downregulation of epg5 (CG14299) in Drosophila resulted in autophagic abnormalities and progressive neurodegeneration. We conclude that EPG5-related Vici syndrome defines a novel group of neurodevelopmental disorders that should be considered in patients with suggestive features in whom mitochondrial, glycogen, or lysosomal storage disorders have been excluded. Neurological progression over time indicates an intriguing link between neurodevelopment and neurodegeneration, also supported by neurodegenerative features in epg5-deficient Drosophila, and recent implication of other autophagy regulators in late-onset neurodegenerative disease

Islamophobia, religious conversion, and belonging in Europe

Being German, Becoming Muslim: Race, Religion, and conversion in the New Europe, by Esra Ozyurek, Princeton, Princeton University Press 2015, 192 pp., ISBN: 9780691162799

The Role of Gender in Descriptive Representation

This article broadens consideration of the gender gap from voting differ ences to the larger question of affective preferences for descriptive represen tation (Pitkin 1967). The results, based on a 1993 survey of 416 individuals, suggest that women are far more likely than men to be "gender conscious" in their evaluation of a candidate or a preferred representative. Differences among the 224 women in the sample can be traced to at least four sources. Group interests and feminist attitudes are positive sources of women's preferences for descriptive representation. Conversely, conservative political views deter some women from supporting women in politics. The results also provide partial support for Carroll's (1987) psychological and economic autonomy thesis. Finally, the results suggest that in part the "gender gap" may be a generational gap most prevalent among "baby boomers."Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline

Characterizing K2 Planet Discoveries: A Super-Earth Transiting the Bright K Dwarf HIP 116454

We report the first planet discovery from the two-wheeled Kepler (K2) mission: HIP 116454 b. The host star HIP 116454 is a bright (V = 10.1, K = 8.0) K1-dwarf with high proper motion, and a parallax-based distance of 55.2 +/- 5.4 pc. Based on high-resolution optical spectroscopy, we find that the host star is metal-poor with [Fe/H] = -.16 +/- .18, and has a radius R = 0.716 +/- .0024 R_sun and mass M = .775 +/- .027 Msun. The star was observed by the Kepler spacecraft during its Two-Wheeled Concept Engineering Test in February 2014. During the 9 days of observations, K2 observed a single transit event. Using a new K2 photometric analysis technique we are able to correct small telescope drifts and recover the observed transit at high confidence, corresponding to a planetary radius of Rp = 2.53 +/- 0.18 Rearth. Radial velocity observations with the HARPS-N spectrograph reveal a 11.82 +/- 1.33 Mearth planet in a 9.1 day orbit, consistent with the transit depth, duration, and ephemeris. Follow-up photometric measurements from the MOST satellite confirm the transit observed in the K2 photometry and provide a refined ephemeris, making HIP 116454 b amenable for future follow-up observations of this latest addition to the growing population of transiting super-Earths around nearby, bright stars.Comment: 16 pages, 8 figures. Accepted by Ap