2,119 research outputs found
Changes in food intake, smoking habits and physical activity before and one year after the end of the COVID-19 lockdown in Spanish population of 20 to 30 years of age
Trabajo de Fin de Máster. Máster en Salud Pública. Curso 2020-2021[EN]
Introduction: The COVID-19 pandemic, that initiated in Wuhan, China presenting its first case on the 17th of november 2019 and in Spain on the 31st of January 2019, represented a massive impact on human health. Not only was the health of the world population affected, but also their lifestyles (food, alcohol and tobacco consumption as well as physical activity) through social distancing and isolation at home that led to social and economic consequences. There have been several studies that demonstrated a change in the customs of people, but none that stated whether this changes that occurred during and due to the pandemic where so strong as to cause a permanent change in the lifestyles.
Material and Methods: A web-based cross-sectional study was conducted, using a questionnaire, on a convenience sample of 659 Spanish adults aged 20–30 years. Study subjects were recruited from 18th of June to 15th of July 2020 and were asked to report the changes they observed in certain food consumption, tobacco consumption, alcohol consumption, and physical activity between before the lockdown and at the time of interview, one-year after the end of the lockdown.
Results: A total of 659 respondents participated in the study (54,4% females.) The population of non-smokers was of 50,8%. Of those smokers that tried to stop smoking (18,6%) 25,5% managed to do so. We have observed a significance difference in the consumption of fruit, meat and coffee between men and women a year after the end of the lockdown. The increase of fruit consumption was greater in men than in women (32,8% vs. 25,8%.) Only 23,7% of men decreased the consumption of meat compared to 34% in women. Women had a tendency to maintain the coffee intake (51,3% of women compared to 41,55 of men.), whereas men had a larger variation of this consumption. Of those who increased the intake of vegetable and fruit the “couples’ where the group most present, forming 30,3% and 28,9% respectively. Of all the participants that decrease the intake of fruit, this was more frequent between those that passed the lockdown alone (30,3%.) Having passed the lockdown in Spain decreased by 46% the probability of increasing the consumption of fish and fish products compared to not having increased it (OR: 0,541, [95%IC: 0,340; 0,863]) as well as decreasing both the probability of increasing the consumption of milk and pre-cooked foods by 58% (OR: 0,421, [95%IC :0,26:0,681]) and 46,5% (OR: 0,535, [95% IC: 0,342; 0,836]), respectively, Passing the lockdown in Spain decreased by 56% (OR: 0,437, [95% IC: 0,273; 0,698]) and 51% (OR: 0,489, [95% IC: 0,309; 0,775]) the probability of having increase in consumption of sweets and chocolate compared to not having increased it. As for the patterns obtained for the smoking habit there was no concrete alteration not even when stratifying. Having passed the lockdown in Spain reduced the probability by 52% of having increased physical activity at the gym compared to not having increased. (OR: 0,482, [95%IC: 0,313;0,743].)
Conclusions: COVID-19 lockdown had a large impact on both the food consumption as well as the physical activity of the Spanish population between the ages of 20-30 years. The fact that those that passed the lockdown outside of Spain increased the exercise at the gym significantly compared to those that passed it in Spain could be associated to the limitations of outdoor exercise during the lockdown inside of Spain. The participants that passed the lockdown with their couple improved their diets, increasing the intake of vegetables and fruits and decreased the alcohol consumption, probably due to positive feedback between the two. The fact that those that passed the lockdown outside out Spain decreased the intake of fresh foods (vegetables and fruits) but increases the consumption of pre-cooked foods, fish, sweets and chocolate could be related to the lack of availability to achieve a Mediterranean diet during this period.
[ES]
Introducción: La pandemia de COVID-19, que se inició en Wuhan, China siendo el primer caso el 17 de noviembre de 2019 y en España el 31 de enero de 2019, representó un impacto masivo en la salud humana. No solo se vio afectada la salud de la población mundial, sino también sus estilos de vida (consumo de alimentos, alcohol y tabaco, así como actividad física) a través del distanciamiento social y el aislamiento en el hogar que tuvo consecuencias sociales y económicas. Se han realizado varios estudios que demostraron un cambio en las costumbres de las personas, pero ninguno que estableciera si los cambios que ocurrieron durante y debido a la pandemia fueron tan fuertes como para provocar un cambio permanente en los estilos de vida.
Material y métodos: Se realizó un estudio transversal en la web, mediante un cuestionario, sobre una muestra de conveniencia de 659 adultos españoles de 20 a 30 años. Los sujetos del estudio fueron reclutados del 18 de junio al 15 de julio de 2020 y se les pidió que informaran los cambios que observaron en el consumo de ciertos alimentos, el consumo de tabaco, el consumo de alcohol y la actividad física entre antes del encierro y en el momento de la entrevista, un año. después del final del encierro.
Resultados: Participaron en el estudio un total de 659 encuestados (54,4% mujeres). La población de no fumadores fue del 50,8%. De los fumadores que intentaron dejar de fumar (18,6%), el 25,5% lo consiguió. Hemos observado una diferencia significativa en el consumo de fruta, carne y café entre hombres y mujeres un año después del final del encierro. El aumento del consumo de frutas fue mayor en hombres que en mujeres (32,8% vs. 25,8%). Sólo el 23,7% de los hombres disminuyó el consumo de carne frente al 34% de las mujeres. Las mujeres tenían una tendencia a mantener la ingesta de café (51,3% de las mujeres frente al 41,55 de los hombres), mientras que los hombres tenían una mayor variación de este. De los que aumentaron la ingesta de verduras y frutas las “parejas” fueron el grupo más presente, formando un 30,3% y un 28,9% respectivamente. De todos los participantes que disminuyeron la ingesta de fruta, este fue más frecuente entre los que pasaron solos el encierro (30,3%). Haber pasado el confinamiento en España disminuyó de un 46% la probabilidad de incrementar el consumo de pescado y productos pesqueros frente a no haberlo incrementado (OR: 0,54,[ IC 95%: 0,340; 0,863]) así como disminuir tanto laprobabilidad de incrementar el consumo de leche y alimentos precocinados en un 58% (OR: 0,421, [IC95%: 0, 26: 0,681]) y 46,5% (OR: 0,535, [95% IC: 0,342; 0,836]), respectivamente. Haber pasado el confinamiento en España disminuyó en un 56% (OR: 0,437, [IC95%: 0,273; 0,698]) y 51% (OR: 0,489, [IC95%: 0,309; 0,775]) la probabilidad de tener aumento en el consumo de dulces y chocolate en comparación con no haberlo aumentado. En cuanto a los patrones obtenidos para el hábito tabáquico no hubo alteración concreta ni siquiera al estratificar. Haber superado el encierro en España redujo en un 52% la probabilidad de haber aumentado la actividad física en el gimnasio frente a no haber aumentado. (OR: 0,482, [95% IC: 0,313; 0,743].)
Conclusiones: El confinamiento del COVID-19 tuvo un gran impacto tanto en el consumo de alimentos como en la actividad física de la población española de entre 20 y 30 años. El hecho de que los que pasaron el confinamiento fuera de España aumentaron significativamente el ejercicio en el gimnasio en comparación con los que lo aprobaron en España podría estar asociado a las limitaciones del ejercicio al aire libre durante el encierro dentro de España. Los participantes que pasaron el confinamiento con su pareja mejoraron sus dietas, aumentaron la ingesta de verduras y frutas y disminuyeron el consumo de alcohol, probablemente debido a la retroalimentación positiva entre los dos. El hecho de que los que pasaron el confinamiento fuera de España disminuyan la ingesta de alimentos frescos (verduras y frutas) pero aumente el consumo de alimentos precocinados, pescado, dulces y chocolate podría estar relacionado con la falta de disponibilidad para lograr una dieta mediterránea.APPRECIATIONS ABSTRACT RESUMEN TABLES AND FIGURES LIST INTRODUCTION MATERIAL AND METHODS Study population Study Design Measures Sociodemographic Information Food Consumption Smoking habits Physical activity Ethics Data Analysis RESULTS Characteristics of Participants Patterns of changes in food consumption Patterns of changes in smoking habits Patterns of changes in physical activity DISCUSSION TABLES AND FIGURES ACTIVITIES DEVELOPED ANNEX 1: ANNEX 2:N
Le azioni a voto plurimo
Il d.l. 24 giugno 2014, n. 91, convertito in L. 11 agosto 2014 n. 116, abrogando il divieto di emissione di azioni a voto plurimo di cui al quarto comma dell'art. 2351 c.c., ha consentito l'emissione di azioni con voto plurimo anche per particolari argomenti o subordinato al verificarsi di particolari condizioni non meramente potestative, prevedendo che ciascuna azione a voto plurimo può avere fino ad un massimo di tre voti. Tale intervento normativo, anche in ottica comparatistica, viene esaminato alla luce dei principi regolatori del diritto societario, tra cui il principio "un'azione un voto" e quello della correlazione proporzionale tra rischio e potere, con lo scopo di indagare l'attuale portata di essi nell'ordinamento, successivamente a tale intervento normativo. Sono, altresì, affrontati gli spazi rimessi all'autonomia privata nella determinazione del contenuto di tali azioni, nonché i profili relativi all'opportunità di una tutela delle minoranze non di controllo in ipotesi di emissione delle predette azioni
Sviluppi presenti e futuri di Nilde
Il presente articolo illustra i più recenti sviluppi del sistema NILDE, le prospettive
di evoluzione futura e le ricadute positive di un modello di lavoro cooperativo
e di condivisione delle esperienze e delle professionalità per la comunità delle
biblioteche aderenti.
La collaborazione con DoGi e l’integrazione di NILDE con questa importante
banca dati, nasce in risposta alle esigenze evidenziate dai bibliotecari dei settori
disciplinari umanistico, sociale e giuridico di lingua italiana.
La collaborazione tra NILDE e Kronosdoc (biblioteche spagnole) e tra NILDE e
ITALE (biblioteche che usano Aleph e Alma) nasce per migliorare i flussi di lavoro di
chi utilizza sia NILDE che altri sistemi per la gestione del document delivery, e per
evitare la duplicazione manuale di inserimento degli stessi dati in software diversi.
Il progetto ALPE per la creazione di un archivio condiviso di licenze dei periodici
elettronici relativi alle clausole di document delivery intende supportare i bibliotecari
nella corretta applicazione degli usi consentiti e favorire la diffusione
delle conoscenze su questi aspetti.This paper presents recent developments of the NILDE system, future plans and
positive follow-up for the community of users. The collaboration with DoGi and the integration with NILDE was born to
answer librarians needs in the human, social and law sectors.
The collaboration between NILDE and Kronosdoc (Spanish libraries) and
between NILDE and ITALE was born for improving the workflow of whom uses
NILDE and these other systems for document delivery and to avoid duplication
of data entry in the two software.
ALPE (Archivio Licenze Periodici Elettronici – e-journal licenses database) is a
pilot project aiming at building a shared national database of ILL permitted uses
about e-resources and to support librarians in the implementation of the correct
policies and the understanding of the issues raised by e-licenses
Design of decorated self-assembling peptide hydrogels as architecture for mesenchymal stem cells
Hydrogels from self-assembling ionic complementary peptides have been receiving a lot of interest from the scientific community as mimetic of the extracellular matrix that can offer three-dimensional supports for cell growth or can become vehicles for the delivery of stem cells, drugs or bioactive proteins. In order to develop a 3D "architecture" for mesenchymal stem cells, we propose the introduction in the hydrogel of conjugates obtained by chemoselective ligation between a ionic-complementary self-assembling peptide (called EAK) and three different bioactive molecules: an adhesive sequence with 4 Glycine-Arginine-Glycine-Aspartic Acid-Serine-Proline (GRGDSP) motifs per chain, an adhesive peptide mapped on h-Vitronectin and the growth factor Insulin-like Growth Factor-1 (IGF-1). The mesenchymal stem cell adhesion assays showed a significant increase in adhesion and proliferation for the hydrogels decorated with each of the synthesized conjugates; moreover, such functionalized 3D hydrogels support cell spreading and elongation, validating the use of this class of self-assembly peptides-based material as very promising 3D model scaffolds for cell cultures, at variance of the less realistic 2D ones. Furthermore, small amplitude oscillatory shear tests showed that the presence of IGF-1-conjugate did not alter significantly the viscoelastic properties of the hydrogels even though differences were observed in the nanoscale structure of the scaffolds obtained by changing their composition, ranging from long, well-defined fibers for conjugates with adhesion sequences to the compact and dense film for the IGF-1-conjugate
Phasic and tonic muscle synergies are different in number, structure and sparseness
In the last two decades, muscle synergies analysis has been commonly used to assess the neurophysiological mechanisms underlying human motor control. Several synergy models and algorithms have been employed for processing the electromyographic (EMG) signal, and it has been shown that the coordination of motor control is characterized by the presence of phasic (movement-related) and tonic (anti-gravity and related to co-contraction) EMG components. Neural substrates indicate that phasic and tonic components have non-homogeneous origin; however, it is still unclear if these components are generated by the same set of synergies or by distinct synergies. This study aims at testing whether phasic and tonic components are generated by distinct phasic and tonic synergies or by the same set of synergies with phasic and tonic activation coefficients. The study also aims at characterizing the differences between the phasic and the tonic synergies. Using a comprehensive mapping of upper-limb point-to-point movements, synergies were extracted from phasic and tonic EMG signal separately, estimating the tonic components with a linear ramp model. The goodness of reconstruction (R2) as a function of the number of synergies was compared, and sets of synergies extracted from each dataset at three R2 threshold levels (0.80, 0.85, 0.90) were retained for further analysis. Then, shared, phasic-specific, and tonic-specific synergies were extracted from the two datasets concatenated. The dimensionality of the synergies shared between the phasic and the tonic datasets was estimated with a bootstrap procedure based on the evaluation of the distribution of principal angles between the subspaces spanned by phasic and tonic synergies due to noise. We found only few shared synergies, indicating that phasic and tonic synergies have in general different structures. To compare consistent differences in synergy composition, shared, phasic-specific, and tonic-specific synergies were clustered separately. Phasic-specific clusters were more numerous than tonic-specific ones, suggesting that they were more differentiated among subjects. The structure of phasic clusters and the higher sparseness indicated that phasic synergies capture specific muscle activation patterns related to the movement while tonic synergies show co-contraction of multiple muscles for joint stabilization and holding postures. These results suggest that in many scenarios phasic and tonic synergies should be extracted separately, especially when performing muscle synergy analysis in patients with abnormal tonic activity and for tuning devices with gravity support
Purchasing power of civil servant health workers in Mozambique
Background: Health workers ’ purchasing power is an important consideration in the development of strategies for health workforce development. This work explores the purchasing power variation of Mozambican public sector health workers, between 1999 and 2007. In general, the calculated purchasing power increased for most careers under study, and the highest percentage increase was observed for the lowest remuneration careers, contributing in this way for a relative reduction in the difference between the higher and the lower salaries. Methods: This was done through a simple and easy-to-apply methodology to estimate salaries ’ capitalization rate, by means of the accumulated inflation rate, after taking wage revisions into account. All the career categories in the Ministry of Health and affiliated public sector institutions were considered. Results: Health workers ’ purchasing power is an important consideration in the development of strategies for health workforce development. This work explores the purchasing power variation of Mozambican public sector health workers, between 1999 and 2007. In general, the calculated purchasing power increased for most careers under study, and the highest percentage increase was observed for the lowest remuneration careers, contributing in this way for a relative reduction in the difference between the higher and the lower salaries. Conclusion: These results seem to contradict a commonly held assumption that health sector pay has deteriorated over the years, and with substantial damage for the poorest. Further studies appear to be needed to design a more accurate methodology to better understand the evolution and impact of public sector healt
Factores extracelulares de Rhizobium leguminosarum y su rol en la formación de biofilms
Esta tesis aporta conocimientos sobre el rol de factores extracelulares producidos por la bacteria fijadora de nitrógeno Rhizobium leguminosarum bv. viciae en la formación de biofilms. Los rizobios se unieron a un soporte abiótico a través de un polo, formando microcolonias y agregados tipo racimo, que culminaron en una estructura tridimensional característica (biofilm) con grupos de bacterias igualmente orientadas. El EPS acídico y el antígeno O del LPS fueron esenciales desde las etapas tempranas (adhesión al soporte y formación de microcolonias). Las EPS-glicanasas PlyA y PlyB, secretadas por el sistema tipo I PrsD-PrsE, influyeron en la maduración del biofilm clivando el EPS. El sistema PrsD-PrsE resultó ser responsable de la secreción de adhesinas tipo Rap, que participarían en las interacciones entre bacterias durante la formación del biofilm. La producción de fibrillas de celulosa estaría reprimida en las cepas estudiadas, aunque la inducción de su síntesis ante determinados estímulos podría influir fuertemente en la agregación celular. Dentro de otro objetivo de esta Tesis, se identificaron los genes de los componentes ABC y MFP de un nuevo sistema de secreción de proteínas tipo I, codificado en el plásmido simbiótico pRL1JI. Este sería responsable de exportar la proteína extracelular EP49, cuya secuencia codificante es contigua. EP49, presentó varias repeticiones de un nonapéptido característico de proteínas de la familia de toxinas RTX, como la rizobiocina A y la proteína formadora de poro NodO de Rhizobium lo que sugiere que interaccionaría con Ca^2+.This Thesis contributes to the knowledge of the role of extracellular factors produced by nitrogen-fixing Rhizobium leguminosarum bv. viciae in biofilm development. Rhizobial attachment to an abiotic surface starts with polar interactions with the surface generating microcolonies and cellular aggregation. Aggregate formation progresses to a typical three-dimensional structure of bacterial clusters. The acidic EPS and the O-antigen of the LPS participate from early stages of biofilm formation (surface adhesion and microcolony establishment). The EPS-glycanases PlyA and PlyB, secreted by PrsD–PrsE type I secretion system influence biofilm maturation by EPS processing. The PrsD-PrsE system was also involved in the secretion of Rap adhesins, which may also participate in bacterial interactions. Cellulose fibrils production seems to be repressed in the Rhizobium leguminosarum strains used in this work; however, induction of its synthesis under certain conditions could strongly influence cellular aggregation. Pursuing other objective of this Thesis, ABC and MFP components of a new type I protein secretion system was identified. These components are encoded by a locus within the pRL1JI symbiotic plasmid and are responsible for the secretion of the extracellular protein EP49, that is encoded downstream of the secretion locus. Several nonapeptide repeats that belong to the RTX toxins family were found in the coding sequence of EP49. These repeats are also present in the rhizobiocin A and the NodO pore forming protein of Rhizobium suggesting that EP49 is a Ca^2+ binding protein.Fil: Russo, Daniela Marta. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina
energy label directive current limitations and guidelines for the improvement
Abstract Energy label is an important strategy to save energy in the household appliances sector. There are many publications related to standards and labels but little information about their potentialities and limits. Although successful standards and labels have been launched in many Countries, their implementation does not have a unique structure, the same energy policy framework and citizens awareness. This study aims to perform an analysis of principal aspects related to Energy Label framework to understand its main potentialities and limitations. Possible strategies to overcome these limits and suggestions to increase its effectiveness are also proposed
Theoretical Exploration of Type I/Type II Dual Photoreactivity of Promising Ru(II) Dyads for PDT Approach
Ru(II)-dyads are a class of bioactive molecules of interest as anticancer agents obtained incorporating an organic chromophore in the light-absorbing metallic scaffold. A careful DFT and TDDFT investigation of the photophysical properties of a series of Ru(II)-polypiridyl dyads containing polythiophene chains of different lengths bound to a coordinating imidazo[4,5-f][1,10]phenantroline ligand, is herein reported. The modulation of the crucial chemical and physical properties of the photosensitizer with the increasing number of thiophene units, has been accurately described investigating the UV-Vis spectra, Type I and Type II photoreactions, also including spin orbit coupling values (SOC). Results show that the low-lying 3IL states afforded as the number of the thiophene ligands increases (n=3,4) are energetically high enough to ensure the singlet oxygen production and can be also involved in electron transfer reaction, showing a dual type I/typeII photeoreactivity
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