Literature Study of The Potential of Moringa Oleifera Leaves Powder Supplementation to Enhance The Coloration of Ornamental Fish

Efforts to maintain good ornamental fish are by providing the quality of feed. The quality of feed is assessed from the best nutritional content as well as economical and can increase the brightness of ornamental fish. Feeds with pigment carotenoids complexes are known to be the main sources of ornamental fish skin pigmentation. A literature study was conducted to explore the benefits of Moringa oleifera leaves powder to improve the color of ornamental fish through carotenoid content. Based on the results of literature studies, supplementation of these natural products has potentially elevated the color brightness of ornamental fish at carotenoid dose 520 mg/kg. Further research on the potential and formulation of M. oleifera leaves powder supplementation impact color brightness of ornamental fish in vivo is very important to explain the mechanism of carotenoids in influencing the physical color brightness of ornamental fis

Case Report: Coccidiosis in Layer Farm, Sumedang

Coccidiosis is a parasitic disease that causes economic losses on chicken farms. A case was found on a farm in Rancaekek, Bandung Regency, where there was a one-year-old laying hen that stopped producing eggs, experienced decreased pectoral muscle mass, and had mild ataxia. The diagnosis was made by necropsy procedure and fecal examination. There were lesions in the small intestine, these lesions manifested as ballooning filled with orange mucus and the presence of petechial hemorrhages on the luminal wall and decreased pectoral muscle mass was found. A Fecal examination was performed using the floating method and the McMaster calculation. The results of the fecal examination revealed Eimeria sp. oocysts and Trichostongylus tenuis eggs. The diagnosis of this case is coccidiosis infection caused by two species of Eimeria sp., namely Eimeria maxima and Eimeria tenella. This infection has resulted in a nutritional deficiency, manifested by a decrease in pectoral muscle mass

Garcinia Mangostana Extract Enhances Skin Epithelialization in Rat Induced Burn Injury

Mangosteen has several important elements for biological activities such as anti-oxidant, anti-inflammatory, anti-bacterial and anti-cancer. There are γ-mangostin, α-mangostin, flavonoids, saponins, and tannins which could stimulate the collagen deposition and accelerate wound healing process. Burn injury cause deep wound in the skin and often cause cicatrix and keloid scar on the skin. However, there is limited information about role of mangosteen in skin wound healing after burn injury. Fifty 10 week-old male rats, were subjected to burn injury using automatic temperature control. Burn injury was created by direct contact of hot plate (170°C) for 15 seconds on rats’ inter scapula region. We elaborated the role of extract mangosteen in skin wound healing by applying daily gel contain with active compound derived from mangosteen. There was no significant weight change during treatment period. We observed that there was significant increase of Epidermal Growth Factors (EGF) expression in 14 as shown in immunohistochemistry and confirmed by western blot protein results. Taken together, mangosteen peel extract-mediated changes in the expression of growth factors in burned rat skins. Mangosteen peel extract might have a role in the acceleration of skin wound healing

PERLINDUNGAN BAGI PASIEN DARI STANDAR PRAKTIK PERAWAT DALAM RANGKA MEWUJUDKAN KEPASTIAN HUKUM

Keperawatan adalah sebuah entitas yang telah diakui secara yuridis, dalam hal penyembuhan, pemulihan, dan pengendalian, berdasarkan ilmu keperawatan. Di Indonesia sekitar 60% tenaga kesehatan merupakan perawat. Banyaknya jumlah perawat di Indonesia ini turut mempengaruhi layanan kesehatan masyarakat, dan ini sangat diperhatikan dalam undang-undang. Pelayanan keperawatan merupakan bagian integral dari pelayanan kesehatan masyarakat. Dengan demikian, perawat sangat mempengaruhi kualitas pelayanan kesehatan selain itu perawat perlu mengamalkan keilmuannya secara otonom sehingga ada kejelasan atas kewenangan dan batas tangung jawab dalam pelayanan kesehatan, untuk totalitas melayani masyarakat. Undang-undang keperawatan dapat menjamin kepastian dan jaminan hukum bagi tenaga perawat dalam melaksanakan pelayanan keperawatan, selain juga dapat menjamin kepastian dan jaminan hukum bagi masyarakat (pasien) yang akan memanfaatkan pelayanan keperawatan. Dengan adanya undang-undang ini diharapkan dapat meningkatkan aksesibilitas, keterjangkauan, dan mutu pelayanan keperawatan, serta mempercepat keberhasilan upaya peningkatan derajat kesehatan masyarakat yang merujuk kepada Standar Praktik Keperawatan. Penelitian ini mempergunakan pendekatan yuridis normatif. Maksud dari istilah,”pendekatan/approach” adalah sesuatu hal atau (perbuatan atau usaha) mendekati, Spesifikasi penelitian yang digunakan adalah metode deskriptif analitis yaitu menggambarkan mengenai peran pelindungan pasien dari standar praktik keperawatan untuk mewujudka kepastian hukum,Sumber-sumber penelitian dalam penelitian ini bahan-bahan hukum primer dan bahan-bahan hukum sekunder,Analisis data pada penelitian hukum normatif pada hakekatnya adalah kegiatan untuk mengadakan ssitematika terhadap bahan-bahan hukum tertulis. Pelaksanaan Standar Praktik Keperawatan yang dilaksanakan dan dipatuhi seperti yang diatur dalam Undang-undang Keperawatan memberikan kepastian hukum bagi pasien dalam mendapatkan pelayanan keperawatan yang prima yang terjamin kualitas dan mutu asuhannya. Kata Kunci : Perlindungan bagi Pasien, Perawat, Standar Praktik Keperawata

Description Of Heart Rate, Respiratory Rate, And Body Temperature Of Haliastur Indus In Kamojang Eagle Conservation Center

Brahminy kite or Halistur indus is one of the protected eagle species in Indonesia. The presence of the eagle in the environment is very important because the eagle is one of many environmental health indicators. Based on the last research of H. indus population in Indonesia, the population of H. indus has decreased due to several factors such as pesticide overuse, destruction of natural habitats, illegal hunting, and illegal trading. Therefore, the conservation programs of H. indus are very important to maintain its population in nature. The purpose of this study is to provide an overview of H. indus’s health including heart rate, respiratory rate, and body temperature who never described on group a group sample in any journal before. The method used in this study was a descriptive method of 15 H. indus in The Kamojang Eagle Conservation Center, Garut, West Java, Indonesia. The result of the heart rate measurement of 15 H. indus obtained the mean and standard deviation was 173.467 ± 11.275 /minute, respiratory rate was 76.400 ± 14.065 /minute, and body temperature was 42.570 ± 0.290 ˚C

Comparative of Neutrophils and Lymphocyte Ratio for Dairy Cattle in Prepartum and Postpartum Condition

There is a transition period that dairy cattle always pass through in their reproduction cycle, making them more stressed. Stress can simply be identified by the ratio of neutrophil (N) and lymphocyte (L) at the haematologic state of dairy cattle. The purpose of this study is to evaluate stress conditions in dairy cattle’s transition period based on neutrophil and lymphocyte ratio. Twenty samples of dairy cattle’s blood in prepartum and postpartum condition are being analyzed with a hematology analyzer. The result of this study shows that the average of neutrophil has increased insignificantly from prepartum to postpartum period as 4.14 103/µL ± 1.51 to 4.27 103/µL ± 2.08 or 1.03% with a normal interval of neutrophil is 1.7-6.0 103/µL. However, the average of lymphocytes decreased insignificantly from 3.23 103/µL ± 1.13 to 3.03 103/µL ± 1.23 or 0.93% with a normal interval of lymphocyte is 1.8-8.1 103/µL. Then, the average of neutrophil and lymphocyte ratio has increased insignificantly from 1.35 103/µL ± 0.46 to 1.47 103/µL ± 0.60 or 1.09%. Based on this result, the ratio of neutrophils per lymphocyte still in the normal range. In the transition period, only a few dairy cattle have a stressful condition. The stress condition in dairy cattle can be identified by increasing neutrophil (neutrophilia) and reducing lymphocyte (lymphocytopenia)

Inhibitory Activity of Boesenbergia rotunda (L.) Mansf. Rhizome towards the Expression of Akt and NF-KappaB p65 in Acetic Acid-Induced Wistar Rats

Ethnopharmacological Relevance. Boesenbergia rotunda has been traditionally used to reduce stomach discomfort in Indonesia. The objective of the present study was to investigate the anti-inflammatory mechanism and acute toxicity of the ethanol extract of B. rotunda rhizome (BREE) in Wistar rats. Materials and Methods. Forty-eight male Wistar rats were divided into anti-inflammatory mechanism study (n = 18) and acute toxicity study (n = 30). The anti-inflammatory mechanism study employed six groups (n = 3), e.g., the normal control, negative control, positive control (quercetin 20 mg/kg BW), and three doses of BREE (250 mg/kg BW; 500 mg/kg BW; 1000 mg/kg BW). All groups (except the normal control) were inflammatory-induced i.p. using 0.1 mL of 1% of acetic acid. The expression of Akt and NF-kappaB p65 in the stomach and intestine of the rats was examined using Western blot analysis. The acute toxicity study (21 days) was conducted by following the Regulation of Indonesia National Agency of Drug and Food Control No. 7/2014 about In Vivo Nonclinical Toxicity Study using 5 doses of BREE (250 mg/kg BW; 500 mg/kg BW; 1000 mg/kg BW; 2000 mg/kg BW; 4000 mg/kg BW). Results. BREE reduces the infiltration of inflammatory cells in both the stomach and the intestine of acetic acid-induced rats. BREE also alters the expression of Akt and NF-kappaB p65 in the rat’s stomach and intestine (p=0.005). The acute toxicity study reveals no lethal effects and behavioral signs of toxicity at all tested doses, which indicates that the LD50 is greater than 4000 mg/kg BW. Conclusion. Taken together, BREE could inhibit the expression of Akt and NF-kappaB p65 in the stomach and intestine of acetic acid-induced Wistar rats. This plant could be further explored for its potential as plant-based antistomach ulceration

Program Peningkatan Pengetahuan untuk Lansia dengan Sindroma Metabolik di Cimahi

ABSTRAK Sindroma metabolik (SM) merupakan masalah kesehatan yang meningkat di seluruh dunia. Di Indonesia, angka penderita sindroma metabolik mencapai 21,8%. Penderita SM meningkat pada lansia karena telah terjadi berbagai kelainan metabolisme. Sehingga diperlukan peningkatan kesadaran masyarakat mengenai komplikasi SM. Masyarakat juga diharapkan untuk mengendalikan faktor resiko SM seperti pengaturan pola aktivitas fisik. Aktifitas fisik seperti olahraga telah terbukti dapat menurunkan resistensi insulin dan memperbaiki profil lipid. Penyuluhan mengenai komplikasi SM dan pengendaliannya dengan cara meningkatkan aktivitas fisik diharapkan dapat memberikan edukasi pada masyarakat. Kegiatan yang dilakukan berupa wawancara mengenai pengetahuan masyarakat mengenai SM dan olahraga yang tepat dalam penanganan sindroma metabolik. Survey pada masyarakat menunjukkan sebagian besar masyarakat (72%) telah mengetahui sindroma metabolik, namun tidak mengetahui penyakit yang dapat disebabkan oleh SM (63%). Disamping itu, hanya 55% responden yang megetahui pengaruh olahraga dalam perbaikan SM. Kegiatan dilanjutkan dengan penyuluhan dan tanya jawab mengenai SM.  Melalui kegiatan pengabdian pada masyarakat ini, diharapkan terjadi perubahan gaya hidup di masyarakat sehingga SM dapat diatasi. Kata Kunci: Lansia, Olahraga, Penyuluhan, Sindroma Metabolik  ABSTRACT Metabolic syndrome (MS) prevalence is increasing worldwide. In Indonesia, MS prevalence was 21.8% in 2018. MS is a risk factor for cardiovascular disease and diabetes. MS risk factor is increased in the elderly. An increase in physical activity has been proven to reduce the MS risk factor. Thus, behavioral changes are the key factor to manage MS. In this community service, we gave education to the elderly population in the Cimahi area, Bandung, West Java about MS was done prior to the education. We found that most of the community members already know about MS. However, only 55% of respondents understand a complication of MS. To educate the local people about the MS prevention program, we gave seminars and counseling. Changes in behavior including diet programs and exercise are the key factor to prevent MS.  Keywords: Elderly, Education, Metabolic Syndrome, Physical Exercis

The pharmacology activities of Angelica keiskei Koidzumi and its efficacy and safety in humans

Chronic exposure to elevated levels of pro-oxidant factors may cause structural failings at the mitochondrial DNA level and alteration of antioxidant enzymes (glutathione peroxidase, catalase, and superoxide dismutase). Oxidative stress is an imbalance between the capacity of endogenous non-enzymatic antioxidants (glutathione, alpha-lipoic acid, uric acid, ferritin, metallothionein, melatonin, and bilirubin) and the occurrence of pro-oxidant factors which may lead to the pathogenesis of various diseases that affects the kidneys, pancreas, central nervous system, and cardiovascular system. Therefore, the utilization of medicinal plants with antioxidant activity, e.g., Angelica keiskei Koidzumi which contains chalcones, is interesting to be explored. Chalcones exhibit direct and indirect antioxidant activity and prevent oxidative stress by decreasing ROS, RNS, and superoxide production. In this review, we discuss the pharmacology activities of A. keiskei Koidzumi and its efficacy in humans. The articles were explored on PubMed and Google Scholar databases and based on the titles and abstracts related to the topic of interest, and 55 articles were selected. Two main chalcones of this plant, 4-hydroxyderricin and xanthoangelol, have been reported for their various pharmacology activities. The efficacy of A. keiskei was confirmed in anti-obesity, hepatoprotective, anti-diabetes mellitus, and increasing plasma antioxidants in patients with metabolic syndrome. A keiskei is safe as proven by only mild or no adverse events reported, thus it is prospective to be further developed as an antioxidant nutraceutical

Correlation Physical Activity, Energy Balance, and Metabolic Syndrome of Physical Fitness in Elderly Age Group

Fitness becomes an important benchmark for public health in every age group. Activities with poor adverse fitness are at risk of injury. Good fitness is gained from a balance in everyday physical activity with conditions that are free of metabolic syndrome. This study investigated the relationship of physical activity, energy balance, and metabolic syndrome to the fitness of 166 professors of Universitas Padjadjaran who underwent a 1-month fitness checkup at BAPELKES Bandung in the period of 2017. Based on the regression analysis, the results showed a significant relationship between physical activity, energy balance, and metabolic syndrome on the physical fitness of the elderly group (F = 25.9290> F table = 2.427) with normal data distribution (Kolmogorov-Smirnov test). The results also showed a moderate relationship (R = 0.569 and R2 = 0.324). It also partially showed significant influence between physical activity and fitness (t = 8.541> t table = 1.975), significant influence between energy balance and physical fitness (t = 2.248> t table = 1.975), and no significant partial influence between metabolic syndrome and physical fitness of the elderly group (t = -0.029 <t table = 1.975). Hence, there is a relationship between physical activity, energy balance, metabolic syndrome and physical fitness  of Professors in Universitas Padjadjaran. Key words: Energy balance, metabolic syndrome, physical fitness    Hubungan Aktivitas Fisik, Keseimbangan Energi, dan Sindrom Metabolik terhadap Kebugaran Fisik pada Kelompok Usia Lanjut Kebugaran menjadi tolak ukur penting bagi kesehatan masyarakat pada setiap kelompok usia. Aktivitas dengan kebugaran usia lanjut yang kurang baik berisiko terjadi cedera. Kebugaran yang baik diperoleh dari keseimbangan dalam aktivitas fisik sehari-hari dengan kondisi bebas dari sindrom metabolik. Penelitian ini mempelajari hubungan aktivitas fisik, keseimbangan energi, dan sindrom metabolik dengan kebugaran 166 orang Guru Besar di Universitas Padjadjaran yang dilakukan pemeriksaan kebugaran selama 1 bulan di BAPELKES Bandung periode tahun 2017. Berdasar atas analisis regresi hasil penelitian menunjukkan hubungan yang signifikan antara aktivitas fisik, keseimbangan energi, dan sindrom metabolik dengan kebugaran fisik kelompok usia lanjut (F=25,9290 > Ftable=2,427) dengan distribusi data normal (tes Kolmogorov-Smirnov). Hasil juga menunjukkan hubungan yang moderat (R= 0,569 dan R2= 0,324). Secara parsial juga menunjukkan pengaruh yang signfikan aktivitas fisik dengan kebugaran (t= 8.541> t tabel= 1.975), pengaruh signifikan keseimbangan energi dengan kebugaran fisik (t= 2,248> t tabel= 1,975), dan tidak ada pengaruh signifikan secara parsial terhadap sindrom metabolik dengan kebugaran fisik kelompok usia lanjut (t= -0,029 < t tabel= 1,975). Berdasar atas hasil penelitian dapat disimpulkan hubungan = aktivitas fisik, keseimbangan energi, dan sindrom metabolik dengan kebugaran fisik guru besar Universitas Padjadjaran. Kata kunci: Kebugaran, keseimbangan energi, sindrom metaboli