Direct torque control of multiphase doubly converter-fed asynchronous machines incorporating the harmonic torques

Doubly fed asynchronous machines have an outstanding property: they can be operated up to twice rated speed delivering full rated torque. This paper presents, for the first time in the literature, a control system for multiphase asynchronous machines fed by Voltage Source Inverters (VSIs) both in stator and rotor that incorporates the harmonic torques. The system has three main and distinctive features: the independent control of the fundamental and harmonic torques, a very fast dynamic response for each one of these torques and a powerful method for selecting the best suited inverter state to achieve the evolution of the fundamental and harmonics flux linkage space phasors prescribed by the external control loops. The first feature is achieved through the decoupling of the multiphase machine provided by the Space Phasor Theory (SPhTh). The second one comes from the application of the General Approach for a very Fast TOrque Control (GAFTOC) principle. The third feature relies on using for multi-phase VSIs a simple but powerful switching-table based mode of operation that overcomes the limitations of the switching-table based modes of operation developed up to now, that only enable for the inverter to feed machines with no harmonic torques contribution

Facilidad para hacer negocios en la Ciudad de Apurímac - Abancay

El presente trabajo de investigación realizado en la ciudad de Abancay – Región Apurímac, demostrará cuan factible resulta emprender un nuevo negocio, considerando las normativas y leyes vigentes en el Perú, analizando cinco pilares fundamentales de acuerdo al Doing Business: Apertura de empresa, permisos de construcción, obtención de electricidad, registro de propiedad, y cumplimiento de contratos. El trabajo se apoya en las mejoras tanto de infraestructura como de tecnología que ahora ofrece la región y que hacen más viable nuevas y mejores alternativas de negocio, para lo cual se desarrollará trabajos de campo que recogerá las experiencias de profesionales y empresarios líderes de la región, El análisis de investigación en la presente tesis que tiene como objetivo general de identificar las condiciones y facilidades para negociar en la ciudad de Abancay, busca fundamentalmente realizar una comparación existente entre el marco normativo vigente y su aplicación en la práctica. El presente estudio es de tipo descriptivo y cualitativo, ya que se pretende identificar y describir las diversas potencialidades con que cuenta la región Apurímac y particularmente la ciudad de Abancay, así mismo presenta un diseño no experimental, debido a que se realiza la investigación sin manipular deliberadamente la variable en estudio. El trabajo de investigación es no experimental, se basa en la observación de fenómenos ocurridos en su contexto real, lo que son insumos para su posterior análisis y se puedan generar correctivos adecuados. Posterior al análisis realizado se concluye que la ciudad de Abancay tiene buenas facilidades para negociar, incluso mayores facilidades que la ciudad capital de Lima; se cuenta con tiempos y costos menores, en algunos casos, que lo que indica el marco normativo y también mejores costos y tiempos que otras ciudades de países como España y ColombiaThe present research work carried out in the city of Abancay - Apurímac Region, will demonstrate how feasible it is to start a new business, considering the regulations and laws in force in Peru, analyzing five fundamental pillars according to the Doing Business: Building permits, obtaining electricity, registering property, enforcing contracts. The work is based on improvements in infrastructure and technology that now offers the region and make more viable new and better business alternatives, for which will develop fieldwork that will collect the experiences of professionals and business leaders in the region. The research analysis in the present thesis that has as general objective to identify the conditions and facilities to negotiate in the city of Abancay fundamentally seeks to make an existing comparison between the normative framework in force and its application in practice. The present study is descriptive and qualitative, since it is intended to identify and describe the diverse potentialities of the Apurimac Region and particularly the city of Abancay, and presents a non - experimental design, due to the fact that the research is done without manipulation Deliberately the variable under study. The research work is nonexperimental, is based on the observation of phenomena occurring in their real context, which are inputs for their subsequent analysis and can generate adequate corrective. After the analysis made, it is concluded that the city of Abancay has good facilities for negotiating, even greater facilities than the capital city of Lima; There are times and lower costs, in some cases, than what the regulatory framework indicates and also better costs and times than other cities in countries such as Spain and ColombiaTesi

Single-cell phenotypic characterization of human pituitary GHomas and non-functioning adenomas based on hormone content and calcium responses to hypothalamic releasing hormones

Producción CientíficaHuman pituitary tumors are generally benign adenomas causing considerable morbidity due to excess hormone secretion, hypopituitarism, and other tumor mass effects. Pituitary tumors are highly heterogeneous and difficult to type, often containing mixed cell phenotypes. We have used calcium imaging followed by multiple immunocytochemistry to type growth hormone secreting (GHomas) and non-functioning pituitary adenomas (NFPAs). Individual cells were typed for stored hormones and calcium responses to classic hypothalamic releasing hormones (HRHs). We found that GHomas contained growth hormone cells either lacking responses to HRHs or responding to all four HRHs. However, most GHoma cells were polyhormonal cells responsive to both thyrotropin-releasing hormone (TRH) and GH-releasing hormone. NFPAs were also highly heterogeneous. Some of them contained ACTH cells lacking responses to HRHs or polyhormonal gonadotropes responsive to LHRH and TRH. However, most NFPAs were made of cells storing no hormone and responded only to TRH. These results may provide new insights on the ontogeny of GHomas and NFPAs.Ministerio de Economía, Industria y Competitividad (Project BFU2012-37146)Instituto de Salud CarlosIII (FIS03/1231

ANEMIA EN LA POBLACIÓN PEDIÁTRICA DEL PERÚ

En el mundo la deficiencia de hierro afecta a 2000 millones de personas y de ellos 1,600 millones tienen anemia por deficiencia de hierro1,2. De ellos un 47,4 % son pre-escolares, 25,4% son escolares, 41,8% son gestantes y 30,2% son mujeres en edad fértil . La severidad del problema es establecida por la OMS según el grado de prevalencia, y se considera severo si afecta a más del 40% de la población, moderado si afecta entre el 20 y 40% de la población, y leve si afecta a menos del 20% . En América Latina se reporta que afecta a 50% de niños menores de 5 años, 75% de niños menores de 2 años; 10 a 30 % de mujeres en edad reproductiva y al 40 a 70% de las mujeres embarazadas . En el Perú existe sub registro de la anemia. MINSA reporta el diagnóstico de anemia ferropénica en sólo 2.1% de las consultas ambulatorias4 , mientras la encuesta ENDES 2015 reporta que el problema es serio para población de niños más pequeños. Según esta última publicación de INEI, el 31% de los niños menores de 5 años encuestados tiene anemia, y está presente en casi 60% de menores de 2 años, en 20,7% de las mujeres entre 15 y 49 años, y en 28% de las gestantes. DOI:https://doi.org/10.25176/RFMH.v16.n2.67

Nuevos recursos didácticos para el aula digital: tradiciones antroponímicas del Madrid multicultural

Este proyecto plantea un trabajo centrado en la elaboración, aplicación docente y evaluación de instrumentos didácticos on-line sobre antroponimia y sus tradiciones en el Madrid multicultural. Persigue aglutinar materiales educativos a disposición de los alumnos a través del Campus Virtual de la Universidad Complutense de Madrid y de las páginas web de los dos Grupos de Investigación implicados en el equipo: “Onomástica y deonomástica” (www.ucm.es/onomastica-deonomastica) y “Organización territorial y administrativa del concejo de Madrid (ss. XIII-XVIII)” (www.ucm.es/documad/). La temática permite ofrecer a todos nuestros alumnos nuevas perspectivas y materiales sobre los estudios antroponímicos que, aunque enmarcados por lo general en el ámbito filológico, han sido también con frecuencia abordados por los historiadores

Brain-Derived Neurotrophic Factor Levels in Cord Blood from Growth Restricted Fetuses with Doppler Alteration Compared to Adequate for Gestational Age Fetuses

Background and Objectives: Fetal growth restriction (FGR) is a severe obstetric disease characterized by a low fetal size entailing a set of undesired consequences. For instance, previous studies have noticed a worrisome association between FGR with an abnormal neurodevelopment. However, the precise link between FGR and neurodevelopmental alterations are not yet fully understood yet. Brain-derived neurotrophic factor (BDNF) is a critical neurotrophin strongly implicated in neurodevelopmental and other neurological processes. In addition, serum levels of BDNF appears to be an interesting indicator of pathological pregnancies, being correlated with the neonatal brain levels. Therefore, the aim of this study is to analyze the blood levels of BDNF in the cord blood from fetuses with FGR in comparison to those with weight appropriate for gestational age (AGA). Materials and Methods: In this study, 130 subjects were recruited: 91 in group A (AGA fetuses); 39 in group B (16 FGR fetuses with exclusively middle cerebral artery (MCA) pulsatility index (PI) 95th percentile). Serum levels of BDNF were determined through ELISA reactions in these groups. Results: Our results show a significant decrease in cord blood levels of BDNF in FGR and more prominently in those with UA PI >95th percentile in comparison to AGA. FGR fetuses with exclusively decreased MCA PI below the 5th percentile also show reduced levels of BDNF than AGA, although this difference was not statistically significant. Conclusions: Overall, our study reports a potential pathophysiological link between reduced levels of BDNF and neurodevelopmental alterations in fetuses with FGR. However, further studies should be conducted in those FGR subjects with MCA PI < 5th percentile in order to understand the possible implications of BDNF in this group.Depto. de Salud Pública y Materno - InfantilFac. de MedicinaTRUEUnión EuropeaComunidad de MadridInstituto de Salud Carlos IIIHalekulani S.LFundación Santiago Dexeus Fontpu

Procesamiento de señales no intrusivas para el monitoreo de condición de emisiones y análisis energético en un motor de combustión interna diésel

El presente trabajo presenta los resultados obtenidos del proyecto «Desarrollo de un sistema de monitoreo para el análisis energético y de condición de emisiones en motores de combustión interna diésel con base en técnicas no intrusivas» financiado en la convocatoria de Colciencias 776 de 2017. La propuesta de investigación establece una metodología que permite realizar análisis energético y de condición de emisiones en motores, trabajando con combustible diésel y biodiésel. El proyecto contribuye a la generación de nuevo conocimiento basado en Ciencia, Tecnología e Información (CTeI) para favorecer la administración y el mantenimiento predictivo de los vehículos. En particular, los diagnósticos son llevados a cabo mediante la captura y estudio de señales experimentales provenientes de motores de combustión interna analizados bajo diferentes parámetros de operación. Este trabajo cuenta con las descripciones técnicas de cada una de las etapas desarrolladas durante el transcurso del proyecto. Así mismo, se condensan los resultados empleados para la consecución de los objetivos planteados en la propuesta

A Clinical Decision Support System (KNOWBED) to Integrate Scientific Knowledge at the Bedside: Development and Evaluation Study

[Background] The evidence-based medicine (EBM) paradigm requires the development of health care professionals’ skills in the efficient search of evidence in the literature, and in the application of formal rules to evaluate this evidence. Incorporating this methodology into the decision-making routine of clinical practice will improve the patients’ health care, increase patient safety, and optimize resources use.[Objective] The aim of this study is to develop and evaluate a new tool (KNOWBED system) as a clinical decision support system to support scientific knowledge, enabling health care professionals to quickly carry out decision-making processes based on EBM during their routine clinical practice.[Methods] Two components integrate the KNOWBED system: a web-based knowledge station and a mobile app. A use case (bronchiolitis pathology) was selected to validate the KNOWBED system in the context of the Paediatrics Unit of the Virgen Macarena University Hospital (Seville, Spain). The validation was covered in a 3-month pilot using 2 indicators: usability and efficacy.[Results] The KNOWBED system has been designed, developed, and validated to support clinical decision making in mobility based on standards that have been incorporated into the routine clinical practice of health care professionals. Using this tool, health care professionals can consult existing scientific knowledge at the bedside, and access recommendations of clinical protocols established based on EBM. During the pilot project, 15 health care professionals participated and accessed the system for a total of 59 times.[Conclusions] The KNOWBED system is a useful and innovative tool for health care professionals. The usability surveys filled in by the system users highlight that it is easy to access the knowledge base. This paper also sets out some improvements to be made in the future.This project has received funding from the Andalusian Ministry of Health from Spain (reference PIN-0213-2016), and FEDER funds.Peer reviewe