Relations Among Neuroticism, Coping, and Distress

Adviser: Dr. Patricia FrazierThis research was supported by the Undergraduate Research Opportunities Program (UROP)

A Mathematical Tool for Optimising Carbon Capture, Utilisation and Sequestration Plants for e-MeOH Production

Carbon capture, utilisation, and sequestration is key for the decarbonisation of hard-to-abate industries, as it allows avoiding the direct release of CO2 to the atmosphere and generating carbon-based products. However, for these products to be truly carbon-neutral, intermittent renewable electricity must be deployed at scale, leading to the necessity of optimising flexible plants with potential for local buffer storages, geological sequestration, and conversion units. The scope of this work is to provide a mathematical framework for the economic optimisation of a carbon capture, utilisation, and sequestration system, to decarbonise a cement plant located in the Puglia region (Italy), via CO2 geological confinement and/or power and CO2-to-methanol conversion. The final aim is to determine the optimal sizing and cost of the process units of the plant, depending on economic conditions such as the methanol sale price and different perspective costs scenarios. The main outcome is an economic convenience of geological sequestration, as opposed to utilisation, while a long-term scenario would allow for a cost-effective production of methanol when the sale price is above 550 EUR/t

Optimisation of ship-based CO2 transport chains from Southern Europe to the North Sea

Among the technologies for climate change mitigation, carbon capture and storage is considered as a technically and economically viable option to reduce CO2 emissions from hard-to-abate industrial sectors. When it comes to CO2 logistics, ship-based chains are emerging as an attractive alternative to other CO2 transport modes (e.g., pipelines), as these could exhibit lower operational risk, higher infrastructural flexibility, and lower costs. This work provides insights into the cost of optimal ship-based CO2 transport chains at a European level, by proposing a detailed economic model of CO2 transport by ship, including all the echelons of the infrastructure (i.e., liquefaction, buffer storage, loading, ship, conditioning, and unloading). The final aim is to determine the minimum CO2 transport cost from Southern Europe to North Sea sequestration. Different unloading scenarios (port-to-port, port-to-floating storage and injection, and port-to-direct offshore unloading) and carbon reduction targets are investigated. The minimum unitary transport cost is 26 €/t of CO2 for transporting 103 Mt/y

Stress analysis of finite anisotropic plates with cutouts under displacement boundary conditions

XI CONGRESO NACIONAL DE MATERIALES COMPUESTOS. Celebrado en Móstoles los días 6, 7 y 8 de julio de 2015The aim of this article is to provide an analytical tool to estímate the stress concentration in anisotropic plates weakened by a circular or elliptical hole; it is achieved by developing Lekhnitskii formalism in order to allow fínite boundary effects to be added (original formulation considers infinite plates). Only membrane problem is herein considered, particularly when prescribed displacements are applied at externa! boundaries, which could simulate boundary conditions of a manhole structure between wing spars. A boundary collocation method in conjunction with a least squares approach is used to solve the problem.Ministerio de Economía y Competitividad de España DPT2012-3718

Looking for sediment distribution and heavy metals contamination: the case study of Neretva Channel (Croatia)

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Sediment Distribution and Trace Metals Contaminations in Neretva Channel (Croazia)

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The effect of FK506 on transforming growth factor beta signaling and apoptosis in chronic lymphocytic leukemia B cells.

Background Loss of response to transforming growth factor-beta (TGF-beta) is thought to contribute to the progression of chronic lymphocytic leukemia. Recent findings of over-activation of the TGF-beta signal in FKBP12-knockout mouse prompted us to investigate whether FK506, the canonical ligand of FKBP, can activate the TGF-beta signal in chronic lymphocytic leukemia. Design and Methods We studied 62 chronic lymphocytic leukemia samples from patients with Rai/Binet stage 0 to 4 disease. The TGF-beta signal was investigated by western blotting and flow cytometry. The levels of Bcl2-family members and death-associated-protein kinase were also investigated by western blotting, whereas apoptosis was studied in flow cytometry. Down-modulation of FKBP12 was obtained by gene silencing with short interfering RNA. Results Twenty-two out of 62 chronic lymphocytic leukemia samples were sensitive to TGF-beta-induced apoptosis. All but two of the responsive samples underwent apoptosis also when cultured with FK506, but not with cyclosporine. Thirteen samples that were not sensitive to TGF-beta were sensitive to FK506. Overall, response to FK506 occurred in 33 samples. FK506 induced Smad2 phosphorylation and nuclear translocation. Accordingly, death-associated-protein kinase, a transcriptional target of Smad, was induced. At the same time, Bcl-2 and Bcl-xL levels decreased whereas the levels of Bim and Bmf increased. A loss of mitochondrial membrane potential preceded caspase activation and cell death. FK506 removed FKBP12 from its binding to the TGF-beta-receptor. FKBP12 release activated the receptor-kinase activity as suggested by the enhanced levels of phospho-Smad found in cells depleted of FKBP12. Conclusions Our study shows that most chronic lymphocytic leukemia cells escape the homeostatic control of TGF-beta and that FK506 restores the TGF-beta signal in a proportion of non-responsive samples. We demonstrated that FK506 activates TGF-beta receptor I kinase activity in chronic lymphocytic leukemia, which transduces apoptosis by a mitochondrial-dependent pathway

Universidades del desarrollo en territorios de reciente constitución: la experiencia de la Universidad Nacional de Tierra del Fuego

In this article, we analyze the project and the institutional trajectory of the National University of Tierra del Fuego (UNTDF), located in a newly constituted territory. First, we review the different institutional models that have emerged for universities and relate them to the experience of UNTDF. Based on the analysis of institutional documents, we point out that its institutional project and other regulations can be related to the model of developmental universities advanced by Arocena, Göransson and Sutz as a model for higher education institutions that focus their third mission on contributing to territorial socioeconomic development. We examine some tensions that have emerged in the last ten years. In this regard, we find that research and contribution to development have been developed to a lesser extent than teaching. This has brought the institution closer to the ‘professionalist’ model that is the norm in the Argentine higher education system.En este artículo, nos proponemos analizar el proyecto y la trayectoria institucional de la Universidad Nacional de Tierra del Fuego (UNTDF), asentada en un territorio de reciente constitución. En primer lugar, analizamos los diferentes modelos institucionales que han surgido para las universidades y los relacionamos con la experiencia de la UNTDF. A partir del análisis de documentos institucionales, señalamos que el proyecto institucional y otras normativas pueden inscribirse en el modelo de universidades del desarrollo propuesto por Arocena, Göransson y Sutz como un modelo para las instituciones de educación superior que focalizan su tercera misión en la contribución al desarrollo socioeconómico territorial. Recogemos algunas tensiones que han emergido en los diez años desde su creación hasta el presente. Al respecto, encontramos que las misiones de investigación y contribución al desarrollo han sido desarrolladas en menor medida que la docencia, y han acercado la institución al modelo profesionalista que es la norma en el sistema universitario argentino

Developmental universities in a new territory: The experience on the National University of Tierra del Fuego

En este artículo, nos proponemos analizar el proyecto y la trayectoria institucional de la Universidad Nacional de Tierra del Fuego (UNTDF), asentada en un territorio de reciente constitución. En primer lugar, analizamos los diferentes modelos institucionales que han surgido para las universidades y los relacionamos con la experiencia de la UNTDF. A partir del análisis de documentos institucionales, señalamos que el proyecto institucional y otras normativas pueden inscribirse en el modelo de universidades del desarrollo propuesto por Arocena, Göransson y Sutz como un modelo para las instituciones de educación superior que focalizan su tercera misión en la contribución al desarrollo socioeconómico territorial. Recogemos algunas tensiones que han emergido en los diez años desde su creación hasta el presente. Al respecto, encontramos que las misiones de investigación y contribución al desarrollo han sido desarrolladas en menor medida que la docencia, y han acercado la institución al modelo profesionalista que es la norma en el sistema universitario argentino.In this article, we analyze the project and the institutional trajectory of the National University of Tierra del Fuego (UNTDF), located in a newly constituted territory. First, we review the different institutional models that have emerged for universities and relate them to the experience of UNTDF. Based on the analysis of institutional documents, we point out that its institutional project and other regulations can be related to the model of developmental universities advanced by Arocena, Göransson and Sutz as a model for higher education institutions that focus their third mission on contributing to territorial socioeconomic development. We examine some tensions that have emerged in the last ten years. In this regard, we find that research and contribution to development have been developed to a lesser extent than teaching. This has brought the institution closer to the ‘professionalist’ model that is the norm in the Argentine higher education system.Fil: Romano, Silvina. Universidad Nacional de Tierra del Fuego. Instituto de Desarrollo Economico E Innovacion; ArgentinaFil: Vasen, Federico. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; Argentin

Streamlining the study of the Tierra del Fuego forest through the use of deep learning

Understanding plant-herbivorous relationships allows to optimize the way to manage and protect natural spaces. In this paper the study of this relationship in the ñire forests (Nothofagus antarctica) of the province of Tierra del Fuego (Argentina) is approached. Using trap cameras to monitor such interaction offers the opportunity to quickly collect large amounts of data. However, to take advantage of its potential, a large investment in trained personnel to analyze and filter the images of interest is required. The present work seeks to establish a path to significantly reduce this obstacle using the advances of machine and deep learning in the recognition of objects from images.XVII Workshop Computación Gráfica, Imágenes y Visualización.Red de Universidades con Carreras en Informátic