248 research outputs found

    Copyright & Online Courses

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    Presentation given at a Lunch & Learn session hosted by the KU Center for Online and Distance Learning on November 13, 2012. The slides in this presentation were based upon an earlier presentation given by Ada Emmett, Scholarly Communication program head, KU Libraries, and Rachel Rolf, Associate Counsel, Office of the General Counsel. A video recording of this presentation is available by clicking on the Published Version link in this record

    Copyright 101 for Authors: Publication Agreements and Open Sharing

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    The video of this presentation is available through the "Other Version" link in this record. The handout and presentation are available below

    Publication Agreements: Going Beyond the Boilerplate for Copyright and Future Access

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    At this session, attendees learned more about publication agreements, copyright, and publicly accessible scholarship. Presenters: Townsend Peterson, Distinguished Professor of Ecology and Evolutionary Biology and Rachel Rolf, attorney with the KU General Counsel’s office

    Applying the Verona Coding Definitions of Emotional Sequences (VR-CoDES) in the dental context involving patients with complex communication needs : an exploratory study

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    This study was conducted as part of a larger collaborative study funded by the EPSRC, between the University of St Andrews and the University of Dundee.Objective The VR-CoDES has been previously applied in the dental context. However, we know little about how dental patients with intellectual disabilities (ID) and complex communication needs express their emotional distress during dental visits. This is the first study explored the applicability of the VR-CoDES to a dental context involving patients with ID. Methods Fourteen dental consultations were video recorded and coded using the VR-CoDES, assisted with the additional guidelines for the VR-CoDES in a dental context. Both inter- and intra-coder reliabilities were checked on the seven consultations where cues were observed. Results Sixteen cues (eight non-verbal) were identified within seven of the 14 consultations. Twenty responses were observed (12 reducing space) with four multiple responses. Cohen's Kappa were 0.76 (inter-coder) and 0.88 (intra-coder). Conclusion With the additional guidelines, cues and responses were reliably identified. Cue expression was exhibited by non-verbal expression of emotion with people with ID in the literature. Further guidance is needed to improve the coding accuracy on multiple providers’ responses and to investigate potential impacts of conflicting responses on patients. Practice implications The findings provided a useful initial step towards an ongoing exploration of how healthcare providers identify and manage emotional distress of patients with ID.PostprintPeer reviewe

    A study of some hepatic immunological markers, iron load and virus genotype in chronic hepatitis C.

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    BACKGROUND/AIMS: Host factors that may influence progression of hepatitis C infection to chronic hepatitis include T-cell responses and iron accumulation. We evaluated the hepatic expression of immunological markers relevant for a cytotoxic response in relation to viral and HFE genotype. METHODS: Frozen liver biopsies were obtained at diagnosis from 28 HFE genotyped patients. Sections stained for CD8, MHC-I, beta(2)m, HFE and CD68 were analyzed blind by morphometry. Response to therapy was available in 12 cases. RESULTS: A negative correlation was found between the number of CD8(+) cells and fibrosis. CD8(+) cells localized as clusters in portal tracts and sinusoids and were seen interacting with MHC-I positive lining cells. MHC-I and beta(2)m were expressed mainly in the endothelial and Kupffer cells. HFE was expressed in most, but not all, round and dendritic CD68(+) cells. Patients with virus genotype 3a had higher hepatic MHC-I and HFE expression, and a better-sustained response to IFN therapy than other patients. CONCLUSIONS: In chronic hepatitis C virus infection MHC-I expression in the liver seems to relate to viral-genotype. In addition, the expression of MHC-I molecules by Kupffer cells places them as probable important players in the host response to HCV.We thank Dr Graça Porto for critical review of the manuscript. This study was supported by the EU QLG1-CT-1999-00665 project, the Calouste Gulbenkian Foundation/FCT Project on Hemochromatosis (Portugal) and the INNOVA Foundation/APBRF (USA)

    An Interferometric View of H-MM1. I. Direct Observation of NH3 Depletion

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    Spectral lines of ammonia, NH3, are useful probes of the physical conditions in dense molecular cloud cores. In addition to advantages in spectroscopy, ammonia has also been suggested to be resistant to freezing onto grain surfaces, which should make it a superior tool for studying the interior parts of cold, dense cores. Here we present high-resolution NH3 observations with the Very Large Array and Green Bank Telescope toward a prestellar core. These observations show an outer region with a fractional NH3 abundance of X(NH3) = (1.975 +/- 0.005) x 10(-8) (+/- 10% systematic), but it also reveals that, after all, the X(NH3) starts to decrease above a H-2 column density of approximate to 2.6 x 10(22) cm(-2). We derive a density model for the core and find that the break point in the fractional abundance occurs at the density n(H-2) similar to 2 x 10(5) cm(-3), and beyond this point the fractional abundance decreases with increasing density, following the power law n (-1.1). This power-law behavior is well reproduced by chemical models where adsorption onto grains dominates the removal of ammonia and related species from the gas at high densities. We suggest that the break-point density changes from core to core depending on the temperature and the grain properties, but that the depletion power law is anyway likely to be close to n (-1) owing to the dominance of accretion in the central parts of starless cores.Peer reviewe
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