Estudio del desarrollo morfológico del neopalio durante la etapa prenatal en alpaca (Vicugna pacos)

El camélido sudamericano representa el componente principal de las actividades productivas del campesino andino, sin embargo, existe limitada información actual sobre las características anatómicas del sistema nervioso de esta especie. Por ello, el objetivo del presente estudio fue describir la anatomía macroscópica del neopalio en fetos de alpaca y así colaborar con el entendimiento de otras disciplinas. Para este estudio se utilizaron 15 fetos con edades gestacionales comprendidas entre los días 101 a 323. A los cerebros se les infiltró formaldehído al 10% mediante inyecciones en la unión frontoparietal y nasofrontal del cráneo. Se esperaron 30 días para posteriormente diseccionarlos y hacer la exposición del neopalio, del cual se tomaron fotografías in situ de la vista dorsal, lateral, rostral y caudal. Con estas fotografías se identificaron a los surcos y giros cerebrales. En orden cronológico los surcos que se describieron fueron: fisura lateral, surco suprasilviano, surco endosagital, surco coronal, surco esplenial, surco genual, surco calcarino, surco presilviano, surco central, surco sagital, surco ectosagital, surco diagonal, surco ectosilviano. Y los giros: giro cingulado, giro silviano rostral, giro silviano caudal, giro sagital, giro poscentral, giro precentral, giro ectosilviano medio, giro ectosilviano caudal, giro ectosagital medio. Además, se evidenció una asimetría entre hemisferios del mismo individuo tanto por el largo y forma de algunos surcos y giros, así como por la ubicación de estos.Perú. Consejo Nacional de Ciencia y Tecnología. Fondo Nacional de Desarrollo Científico y Tecnológico (Fondecyt). 025-2016-FONDECY

Evaluation of positive mental heath and sense of coeherence in mental health professionals

BACKGROUND: !e Sense of Coherence (SOC) of Antonowsky (1996) which is based on salutogenic theory and the multifactor Positive Mental Health (PMH) model of Lluch (1999) provide two constructs for comprehending, evaluating, and intervening in the promotion and maintenance of a good state of mental health. AIM: Were assessed self-rated mental health of health professionals working in mental health services and relations between both constructs and sociodemographic, work, and health variables. METHODS: !e sample was made up of n=102 attending professionals at the mental health units of the Parc Hospitalari Martí i Julià, in Salt, Girona. !e variables studied were sociodemographic work-related, health-related, and self-perception of mental health, evaluated by means of the Sense of Coherence questionnaire and the Positive Mental Health questionnaire. !e questionnaires were self-administered. RESULTS: Overall, the sample studied scored high in the Sense of Coherence and the Positive Mental Health questionnaires. In terms of the relation between the overall scores of the SOC questionnaire and the PMH, analysis revealed a positive relation between the two. CONCLUSIONS: !is positive relation between the two questionnaires may be of particular interest in future studies of the multifactor model of Positive Mental Health and the salutogenic model that underlies the Sense of Coherence, by generating a global conceptual framework for the study of mental health from a positive perspective.info:eu-repo/semantics/publishedVersio

La puerta de mi escuela. Reflexiones y experiencias en el aula de Educación Especial.

A lo largo de los siglos, se ha podido ver reflejada una clara evolución en lo que respecta a las personas con capacidades diferentes. A través de la realización de este proyecto se puede ver, por un lado, el avance respecto a la posición y los derechos de personas con discapacidad y, por otro, la necesidad, a día de hoy, de las aulas de Educación Especial en todos los centros. Todo ello, queda reflejado a través de la experiencia en CEIP Montecorona que cuenta con una clase con este tipo de características. Finalmente, con este trabajo, se busca una concienciación de la sociedad en lo que respecta a las personas con diversidad funcional y su educación

Toxocaríase humana: inquérito soroepidemiológico na cidade amazônica de Yurimaguas, Peru

The aim of this study was to determine the seroprevalence of the infection by Toxocara in the general population of the Amazonian city of Yurimaguas, Peru. From March to August 2008, a total of 300 subjects were sampled and tested by means of a Toxocara ELISA-IgG test. A clinical and epidemiological questionnaire was used to assess the symptomatology and risk factors associated with human toxocariasis. The overall rate of seropositivity was 35.66%, with a significant high proportion in children (p < 0.001). The clinical evaluation revealed that 95.33% of the seropositive group had some type of symptomatology: headache (66.36%), respiratory compromise (63.55%), abdominal pain (54.21%), cutaneous signs (40.19%) and ocular manifestations (36.45%), and almost all of them were statistically significant (p < 0.001). Furthermore, 56.07% of the seropositive subjects presented at least one intestinal pathogen parasite with predominance of helminthes, but without significant association (p = 0.334). The analysis of risk factors showed only that the use of public places and geophagia exhibited a significant association with the seropositivity (p < 0.001). Clinical, serological and epidemiological findings associated to infection with Toxocara were observed in the present study and future studies should be done to assess this serious health problem.O objetivo do presente estudo foi estimar a soroprevalência da infecção por Toxocara em população geral da cidade de Yurimaguas, Peru. Entre os meses de Março e Agosto de 2008, foi estudado um total de 300 pessoas por exame imunológico mediante Toxocara ELISA-IgG teste. Uma ficha clínico-epidemiológica foi utilizada para avaliar a sintomatologia e os fatores de risco associados à toxocaríase. A freqüência geral de anticorpos na população foi de 35,66% com proporção significativamente maior de positividade em meninos de um a 10 anos (p < 0.001). A avaliação clínica revelou que 95.33% do grupo de soropositivos apresentava algum tipo de sintomatologia associada à toxocaríase: 66,36% cefaléia, 63,55% sintomas respiratórios, 54,21% dor abdominal, 40,19% sinais cutâneos e 36,45% manifestações oculares e quase todos estes sinais foram estatisticamente associados ao resultado da sorologia (p < 0.001). Além disso, 56,07% das pessoas com sorologia positiva tinham pelo menos algum parasito intestinal patogênico e com predominância de helmintos, mas sem nenhuma associação significativa (p = 0.334). A análise dos fatores de risco mostrou que o uso de lugares públicos e história de geofagia tiveram significativa associação com a sorologia positiva (p < 0,001). Conclui-se que existem evidências clínicas, sorológicas e epidemiológicas de infecção por Toxocara na população estudada e futuros estudos são necessários para avaliar este sério problema de saúde pública

Evaluación de los antígenos totales de Fasciola hepatica como agente de absorción de anticuerpos inespecíficos en el inmunodiagnóstico de la toxocarosis humana

Objetivos: Evaluar la capacidad de absorción de anticuerpos inespecíficos de antígenos totales de adultos de Fasciola hepatica frente a los de Ascaris suum, para mejorar el serodiagnóstico de toxocarosis humana. diseño: Observacional, descriptivo Institución: Instituto de Medicina Tropical Daniel A. Carrión, Facultad de Medicina, UNMSM. Participantes: Se recolectó sueros de pacientes con toxocarosis, otras helmintiasis y de personas aparentemente sanas. Se preparó antígenos TES de Toxocara canis, de Fasciola hepatica y de Ascaris suum. Intervenciones: SDS-PAGE y western blot. Principales medidas de resultados: Los antígenos fueron analizados por SDS-PAGE y western blot y la capacidad de absorción de anticuerpos inespecíficos mediante ELISA y western blot. Resultados: Por SDS-PAGE y western blot se determinó que el extracto antigénico de F. hepatica posee bandas antigénicas 8, 12, 17, 23, 27, 30, 36, 43, 66 y 136 KDa y que logra reducir las reacciones cruzadas en forma similar a los antígenos de A. suum. Mediante western blot se observó que el antígeno de 67 KDa de los antígenos TES posee cierta reactividad cruzada con alguno de los componentes del extracto antigénico de F. hepatica. Conclusiones: El extracto antigénico de F. hepatica puede ser utilizado para la absorción de anticuerpos inespecíficos en el inmunodiagnóstico de toxocarosis humana

Copper nitride: a versatile semiconductor with great potential for next-generation photovoltaics

Copper nitride (Cu3N) has gained significant attention recently due to its potential in several scientific and technological applications. This study focuses on using Cu3N as a solar absorber in photovoltaic technology. Cu3N thin films were deposited on glass substrates and silicon wafers by radio-frequency magnetron sputtering at different nitrogen flow ratios with total pressures ranging from 1.0 to 5.0 Pa. The thin films' structural, morphology and chemical properties were determined by XRD, Raman, AFM and SEM/EDS techniques. The results revealed that the Cu3N films exhibited a polycrystalline structure, with the preferred orientation varying from (100) to (111) depending on the working pressure employed. Raman spectroscopy confirmed the presence of Cu-N bonds through characteristic peaks observed in the 618-627 cm-1 range. While SEM and AFM images confirmed the presence of uniform and smooth surface morphologies. The optical properties of the films were investigated using UV-VIS-NIR spectroscopy and photothermal de-flection spectroscopy (PDS). The obtained band gap, refractive index, and Urbach energy values demonstrated promising optical properties for Cu3N, indicating their potential as solar absorbers in photovoltaic technology. This study highlights the favorable properties of Cu3N films deposited by the RF sputtering method, paving the way for their implementation in thin-film photovoltaic technologies. These findings contribute to the progress and optimisation of Cu3N-based materials for efficient solar energy conversion

Freqüência de toxocaríase humana numa população rural de Cajamarca, Peru, mediante o uso do teste DOT-ELISA

The aim of this study was to estimate the frequency of human toxocariasis in Cauday district, Cajamarca, Peru, using a dot-ELISA test. From June to October 2005, a total of 256 adult subjects were studied. Blood samples were collected for serology by a dot-ELISA test and for hematological examination. Parasitological examination was also carried out in stool samples to check cross-reactions in the dot-ELISA. The frequency observed was 44.92%, with a significant higher proportion of positivity in male subjects. From subjects with positive serology, 45.6% had respiratory symptoms, 40.44% abdominal pain, 32.35% hepatic symptoms, 14.7% cutaneous signs, 13.23% ocular manifestations, 43.38% eosinophilia, and all of these were statistically associated to serology. Among the population evaluated, 90.23% (231/256) were parasitized. From subjects with positive serology, 92.17% had at least one intestinal parasite and the most frequent were: Blastocystis hominis (68.38%), Giardia lamblia (28.68%), Hymenolepis nana (20.0%), Ascaris lumbricoides (15.65%), Entamoeba histolytica/E. dispar (13.24%), Cyclospora cayetanensis (4.41%), Cryptosporidium sp. (1.47%), Enterobius vermicularis (0.87%), Strongyloides stercoralis (0.87%), Taenia sp. (0.87%), and Trichuris trichiura (0.87%). The rate of false positives in the dot-ELISA test was improved by serum absorption each with A. suum antigens, with a decrease of cross-reactions. In conclusion, human toxocariasis is highly frequent in this population and some risk factors like dog/cat ownership, presence of pets within house, and previous history of geophagia were observed in the present study.O propósito do presente estudo foi estimar a freqüência da toxocaríase no distrito de Cauday, Cajamarca, Peru, usando o dot-ELISA teste. Entre junho e outubro de 2005, um total de 256 pessoas foram avaliadas. Coletaram-se amostras de sangue para o teste de dot-ELISA e para o exame hematológico e amostras de fezes para exame parasitológico. A freqüência geral de anticorpos anti-Toxocara observada foi de 44,92%, com maior proporção significativa de positividade em pessoas do sexo masculino. Das pessoas com sorologia positiva, 45,6% apresentavam sintomas respiratórios, 40,44% dores abdominais, 32,35% moléstias hepáticas, 14,7% sinais cutâneos, 13,23% manifestações oculares, 43,38% eosinofilia e todos estes fatores foram estatisticamente associados à sorologia. Entre as pessoas avaliadas 90,23% estavam parasitadas e 92,17% das pessoas com sorologia positiva tinham algum parasito intestinal, sendo os mais freqüentes: Blastocystis hominis (68,38%), Giardia lamblia (28,68%), Hymenolepis nana (20,0%), Ascaris lumbricoides (15,65%), Entamoeba histolytica/E. dispar (13,24%), Cyclospora cayetanensis (4,41%), Cryptosporidium sp. (1,47%), Enterobius vermicularis (0,87%), Strongyloides stercoralis (0,87%), Taenia sp. (0,87%) e Trichuris trichiura (0,87%). A taxa de falsos positivos no teste dot-ELISA foi melhorada pela absorção dos soros com antígenos de A. suum, com diminuição das reações cruzadas. Em conclusão, a toxocaríase humana é altamente freqüente nesta população e fatores de risco como ter um cão/gato, presença dos animais dentro de casa e estória prévia de geofagia foram observados durante o presente estudo

Deleted in malignant brain tumor 1 (DMBT1) expression pattern in normal cervix and at different stages of squamous intraepithelial lesions

Background: Cervical cancer is one of the most frequently occurring malignancies in women worldwide, with high mortality rates. Cervical Squamous Cell Carcinoma (SCC) presents previous states of non-invasive precursor lesions, and early stage Low-Grade Squamous Intraepithelial Lesions (LSIL) regress to normal or Atypical Squamous Cells of Undetermined Significance (ASCUS) in approximately 50% of cases. Deleted in Malignant Brain Tumors 1 (DMBT1) is a tumour suppression glycoprotein, which absence is considered a malignancy marker in many epithelial cancers. Objective: To analyse DMBT1’s presence and localization in SCC and precursor lesions. Method: Immunohistochemistry for DMBT1 was performed in cervix biopsies classified as normal, LSIL, HSIL and SCC. Results: DMBT1 was detected at the supranuclear and sometimes infranuclear regions of the endocervix monolayer epithelial cells in normal and HSIL biopsies. In LSIL samples the detection of DMBT1 in endocervix was variable between patients. Also variable was DMBT1 staining in cells of glandular epithelium. The glycoprotein was not detected in the stratified epithelium of the exocervix, regardless of the lesion grade; nor in dysplastic cells. Conclusion: The absence of DMBT1 from endocervix only in some samples of LSIL is promising as a candidate for possible lesion regression potential marker.Fil: Valero, Andrés. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; ArgentinaFil: Roldán, María Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; ArgentinaFil: Ruiz, Maria Fernanda. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; ArgentinaFil: Teijeiro, Juan Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnol.conicet - Rosario. Unidad de Direccion; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; ArgentinaFil: Marquez, Susana Beatriz. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; ArgentinaFil: Marini, Patricia Estela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; Argentin

Resilience and job satisfaction among out‐of‐hospital emergency medical service professionals: a cross‐sectional multi‐centric study

Aim: We aim to describe the relationship between job satisfaction and compare levels of resilience among out-of-hospital emergency medical service professionals. Background: The study of the impact of the working environment on health professionals has raised great interest. Job-related variables and resilience can be a protective factor against stressful and demanding events at work. Methods: A cross-sectional survey comprising sociodemographic and job-related variables was conducted among 406 workers (doctors, nurses, psychologists, and ambulance technicians) from the out-of-hospital emergency medical system in Spain. Resilience was self-reported using the Connor-Davidson Resilience Scale. Results: Nursing professionals were less resilient compared with ambulance technicians (score difference 1.709, p = .008). As age increased, resilience was lower (r = -.118). Professionals with higher resilience scores were more satisfied in their work (OR = 1.06, 95% CI: 1.02-1.11), and professionals with higher psychological strength, gained from working with other colleagues, also showed greater job satisfaction (OR = 5.47, 95% CI: 2.55-11.73). Conclusion: There was a positive association between resilience, job satisfaction and collaborative work. Professionals with greater psychological strength, gained from working with other colleagues, also showed higher levels of job satisfaction. Implications for nursing management: Managers can use these results to influence the work environment to enhance job satisfaction and hence improve the resilience of the out-of-hospital emergency health care professionals

Mirar la escritura en la educación superior como un prisma

Escribir es una tarea cotidiana de cualquier ciudadano y profesional, sin embargo, cuando hablamos de escribir en ámbitos disciplinares específicos parece que esta actividad se convierte en un gran desafío, más aun si la pensamos en relación a los cambios que se vienen generando en la sociedad del conocimiento, en las formas de gestionar socialmente el saber (Monereo y Pozo, 2003). Preocupados por este problema, nos propusimos investigar las consignas de escritura en el nivel superior, considerándolas formaciones discursivas que median y regulan las actividades cognitivas de los alumnos, e indagando, particularmente, las características que asumen las mismas en las carreras de Licenciatura y Profesorado en Ciencias Biológicas. En este escrito compartiremos la estrategia metodológica que hemos diseñado para abordar este estudio que se lleva a cabo en el contexto de una Universidad Pública de la Provincia de Córdoba, Argentina, haciendo hincapié en la potencialidad del uso de la triangulación analítica (Rodríguez Sabiote, Pozo Lorrente, Gutiérrez Pérez, 2006) como recurso metodológico que nos permite aproximarnos y abordar nuestro objeto de investigación desde diferentes perspectivas. Especialmente, nos proponemos dialogar y argumentar posicionamientos teóricos que nos permitan justificar la elección del criterio de triangulación analítica como herramienta de investigación y abordaje estratégico de nuestro objeto de estudio en su complejidad.Fil: Roldán, Carolina Isabel. Universidad Nacional de Rio Cuarto. Facultad de Cs.exactas Fisicoquímicas y Naturales. Departamento de Cs.naturales. Cátedra de Epistemología y Didactica de Las Ciencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Vazquez, Alicia Margarita. Universidad Nacional de Río Cuarto; ArgentinaFil: Rivarosa, Alcira Susana. Universidad Nacional de Río Cuarto; Argentin