Status of local soil contamination in Europe: Revision of the indicator “Progress in the management contaminated sites in Europe”

On this report the findings of the questionnaire commissioned by the European Commission Joint Research Centre for the revision of the Indicator "Progress in the management of contaminated site in Europe" in 2016 are presented. It has been produced with the contribution of data provided by the National Reference Centres (NRCs) in member states and cooperating countries within EIONET and funded by the country to work with the EEA and relevant European Topic Centres (ETCs) in specific thematic areas related to the EEA work programme. The NRCs Soil are nationally funded experts, or groups of experts, in organisations which are regular collectors or suppliers of soil data at the national level and/or possess relevant knowledge of specific environmental issues, monitoring or modelling. NRC Soil plays a role in the technical coordination of these topics and work with the EEA, the European Commission’s Joint Research Centre (JRC) and the ETC on Urban, land and soil systems (ETC/ULS). An analysis of the information extracted from the Soil Wiki platform, which contains an overview of European and national soil-related policy instruments is also presented. The Land and Soil Indicator LSI003 aims to answer the following policy-relevant questions: What is the estimated extent of soil contamination? How much progress has been achieved in the management and control of local soil contamination? Which sectors contribute most to soil contamination? What are the main contaminants affecting soil and groundwater in and around Contaminated Sites? How much is spent on cleaning up soil contamination? And how much of the public budget is used? An overall improvement in the management of contaminated sites in Europe has been observed. For the total of the 39 surveyed countries, 2.5 million sites have been estimated where polluting activities have taken place considering the artificial surface. Nowadays, there are more than 650 000 registered sites where polluting activities took/are taking place in national and regional inventories of replying countries; more than 65 500 sites have been remediated. Efforts are mainly focused on investigation and remediation of sites where polluting activities took/are taking place due to many countries already have an accurate inventory. Overall, the production sectors contribute more to local soil 'pollution' than the service sectors (60 % compared to 32 %). The most frequent contaminants are mineral oils and heavy metals. The most commonly used remediation procedure seems to be the ex-situ technique “dig-and-dump”, which implicates the excavation and off-site disposal of contaminated soil. With the available data provided by replying countries, the average overall expenditures to assess soil 'pollution' account for €4.3 billion where on average more than 32 % of total expenses comes from public budget.JRC.D.3-Land Resource

A small step or a giant leap : accounting for settlement delay and dispersal in restoration planning

Funding: The project was funded by the Nesbit Cleland Trust (St Abbs Marine Station), Royal Haskoning DHV, Nature Scotland and the MASTS pooling initiative (the Marine Alliance for Science and Technology for Scotland). MASTS is funded by the Scottish Funding Council (grant reference HR09011).Understanding larval duration and hence dispersal potential of the European oyster Ostrea edulis is crucial to inform restoration strategies. Laval duration has an obligatory period of maturity to pediveliger (when larvae are ready to settle), but also an unknown period until metamorphosis is triggered by a settlement cue. The extent to which larvae can prolong the pediveliger period and delay metamorphosis has not been studied. Here we show that O. edulis larvae can delay metamorphosis for a period of 11 days, while retaining the capability to settle in high proportions when presented with a suitable settlement cue. O. edulis larvae are likely to be able to delay metamorphosis even further, since 80% of larvae in the control treatment were still alive when the experiment was terminated at day 14. The results indicate the ability of O. edulis larvae to more than double pelagic duration and probably further delay metamorphosis. We discuss these findings in the context of larval mortality, and the importance of O. edulis' larval settlement requirements for dispersal potential, recruitment success and connectivity of restoration sites.Publisher PDFPeer reviewe

Las compañías de bajo coste y sus usuarios. El caso de España

El objeto de este estudio es analizar el perfil sociodemográfico de los turistas desplazados a España en Compañías Aéreas de Bajo Coste durante el año 2006, y a su vez compararlo con el de los turistas que viajaron en las Compañías Aéreas Tradicionales. Los resultados muestran una asociación entre el uso de los dos tipos de compañías aéreas y una serie de variables analizadas = The main of this study is to analyze the tourists sociodemographic profile which have been move in Low Cost Carriers to Spain in 2006, and at the same time, to make a comparative with Traditional Carriers tourists. The results show an association between the use of these two types of carriers and some analyzed variable

Estudio De La Imagen De Marca De Las Entidades Financieras

Esta investigación realiza un estudio de la imagen de marca de distintas entidades financieras que operan en España. Para llevar a cabo esta investigación se utiliza una técnica de marketing denominada Evaluación Periódica de la Imagen (EPI), que proporciona una combinación de las ventajas de las técnicas cuantitativas y cualitativas. Los resultados obtenidos muestran que las dos entidades financieras percibidas más iguales entre sí son La Caixa y Caja Madrid; por el contrario, las dos entidades percibidas más diferentes son el Santander y Caja Madrid. Finalmente, el estudio muestra la imagen relativa, imagen individual y un mapa de posicionamiento de las entidades analizadas

The Thymus in Chagas Disease: Molecular Interactions Involved in Abnormal T-Cell Migration and Differentiation

Chagas disease, caused by the protozoan parasite T. cruzi, is a prevalent parasitic disease in Latin America. Presently, it is spreading around the world by human migration, thus representing a new global health issue. Chronically infected individuals reveal a dissimilar disease progression: while nearly 60% remain without apparent disease for life, 30% develop life-threatening pathologies, such as chronic chagasic cardiomyopathy (CCC) or megaviscerae. Inflammation driven by parasite persistence seems to be involved in the pathophysiology of the disease. However, there is also evidence of the occurrence of autoimmune events, mainly caused by molecular mimicry and bystander activation. In experimental models of disease, is well-established that T. cruzi infects the thymus and causes locally profound structural and functional alterations. The hallmark is a massive loss of CD4+CD8+ double positive (DP) thymocytes, mainly triggered by increased levels of glucocorticoids, although other mechanisms seem to act simultaneously. Thymic epithelial cells (TEC) exhibited an increase in extracellular matrix deposition, which are related to thymocyte migratory alterations. Moreover, medullary TEC showed a decreased expression of AIRE and altered expression of microRNAs, which might be linked to a disrupted negative selection of the T-cell repertoire. Also, almost all stages of thymocyte development are altered, including an abnormal output of CD4−CD8− double negative (DN) and DP immature and mature cells, many of them carrying prohibited TCR-Vβ segments. Evidence has shown that DN and DP cells with an activated phenotype can be tracked in the blood of humans with chronic Chagas disease and also in the secondary lymphoid organs and heart of infected mice, raising new questions about the relevance of these populations in the pathogenesis of Chagas disease and their possible link with thymic alterations and an immunoendocrine imbalance. Here, we discuss diverse molecular mechanisms underlying thymic abnormalities occurring during T. cruzi infection and their link with CCC, which may contribute to the design of innovative strategies to control Chagas disease pathology.Fil: Perez, Ana Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Inmunología Clinica y Experimental de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Instituto de Inmunología Clinica y Experimental de Rosario; ArgentinaFil: de Meis, Juliana. Fundación Oswaldo Cruz; BrasilFil: Rodriguez Galan, Maria Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Savino, Wilson. Fundación Oswaldo Cruz; Brasi

Comparison of pepper accessions acting as rootstocks: A case with low P inputs

Fertilization is essential for maintaining production in agriculture. Yet, in too high quantity it causes high impact in environment and in farmers economy. This is especially true in the case of phosphorus (P) fertilization. Finding genotypes adapted to low P conditions may help to reduce the problem. P efficiency depends to some extend on the ability of the roots to acquire this mineral, therefore using efficient rootstocks would provide a higher acquisition of P, maintaining the good characteristics of the scion varieties. In this study, twenty diverse pepper accessions (Capsicum annuum L.) have been evaluated as possible rootstocks to increase P acquisition and yield in pepper under no P fertilization. Plant production, biomass, P content and physiological phosphorous use efficiency were evaluated for ‘Lobo’ variety grafted onto different rootstocks. In addition, root traits, measured manually (shovelomics) and semi-automatically (Winrhizo) were studied. The results showed a great diversity in the root traits for the studied accessions. These root traits changed significantly when the accessions act as rootstock, indicating great rootstock/scion interactions. In general, all the rootstocks adapted their root size and shape to that displayed by ‘Lobo’ root system. Some accessions seemed to have some incompatibility whereas some others enhanced the scion performance. It was possible to identify some genotypes suitable to act as rootstocks for pepper with good performance under low P conditions. Root length, root weight, branching, and root angle were identified as key root traits for plant growth and P acquisition under low P conditions

Quantitative indices of student social media engagement in tertiary education: a systematic review and a taxonomy

Recent studies have evaluated the use of social media as learning aids in tertiary education. Emerging research in this area has focused primarily on non-quantitative approaches to student social media engagement. However, quantitative engagement outcomes may be extracted from student posts, comments, likes, and views. The goal of the present review was to provide a research-informed taxonomy of quantitative and behavior-based metrics of student social media engagement. We selected 75 empirical studies comprising a pooled sample of 11,605 tertiary education students. Included studies used social media for educational purposes and reported student social media engagement outcomes (source databases: PsycInfo and ERIC). We used independent raters and stringent interrater agreement and data extraction processes to mitigate bias during the screening of references. Over half of the studies (52%, n =39) utilized ad hoc interviews and surveys to estimate student social media engagement, whereas thirty-three studies (44%) used some form of quantitative analysis of engagement. Based on this literature, we present a selection of countbased, time-based, and text-analysis metrics. The proposed taxonomy of engagement metrics resulting provides the methodological basis for the analysis of social media behavior in educational settings, particularly, for human operant and behavioral education studies. Implications for future research are discussedFunding Open Access funding enabled and organized by Council of Australian University Libraries and its member The University of Auckland. The frst author received a one-year research contract funded through a Ramon y Cajal Fellowship (Ministerio de Ciencia e Innovación, Spain) awarded to second author (reference no. RYC-2016-20706). This work was supported by a research contract between ABA España (Madrid, Spain) and The University of Auckland (Auckland, New Zealand) (project no. CON02739

Clinical and Laboratory Development of Echinocandin Resistance in Candida glabrata: Molecular Characterization

The pathogenic yeast Candida glabrata has become a public health issue due to the increasing number of echinocandin resistant clinical strains reported. In this study, acquisition and development of resistance to this antifungal class were studied in serial C. glabrata isolates from five patients admitted in two Spanish hospitals with a resistant profile against echinocandins associated with different mutations in hot-spot 1 of FKS2 gene. For two of these patients susceptible FKS wild-type isolates obtained prior to resistant ones were also investigated. Isolates were genotyped using multilocus sequence typing and microsatellite length polymorphism techniques, which yielded comparable results. Susceptible and resistant isolates from the same patient had the same genotype, being sequence type (ST) 3 the most prevalent among them. Isolates with different FKS mutations but the same ST were present in the same patient. MSH2 gene alterations were also studied to investigate their correlation with antifungal resistance acquisition but no association was found with antifungal resistance nor with specific genotypes. In vitro exposure to increasing concentrations of micafungin to susceptible isolates developed colonies carrying FKS mutations in agar plates containing a minimum concentration of 0.06 mg/L of micafungin after less than 48 h of exposure. We investigated the correlation between development of resistance and genotype in a set of susceptible strains after being in vitro exposed to micafungin and anidulafungin but no correlation was found. Mutant prevention concentration values and spontaneous growth frequencies after selection with both echinocandins were statistically similar, although FKS mutant colonies were more abundant after micafungin exposure (p < 0.001). Mutation S663P and F659 deletion were the most common ones found after selection with both echinocandins.This work was supported by the Fondo de Investigación Sanitaria (Grant FI14CIII/00025 to OR-M and research projects PI13/02145 and PI16CIII/00035 to AA-I), and also supported by the Plan Nacional de I+D+i 2013–2016 and Instituto de Salud Carlos III, Subdirección General de Redes y Centros de Investigación Cooperativa, Ministerio de Ciencia, Innovación y Universidades, Spanish Network for Research in Infectious Diseases (REIPI RD16CIII/0004/0003) – co-financed by the European Development Regional Fund “A way to achieve Europe,” Operative Program Intelligent Growth 2014–2020.S