Faint emission lines in the Galactic H II regions M16, M20 and NGC 3603

We present deep echelle spectrophotometry of the Galactic {\hii} regions M16, M20 and NGC 3603. The data have been taken with the Very Large Telescope Ultraviolet-Visual Echelle Spectrograph in the 3100 to 10400 \AA range. We have detected more than 200 emission lines in each region. Physical conditions have been derived using different continuum and line intensity ratios. We have derived He$^{+}$, C$^{++}$ and O$^{++}$ abundances from pure recombination lines as well as abundances from collisionally excited lines for a large number of ions of different elements. We have obtained consistent estimations of the temperature fluctuation parameter, {\ts}, using different methods. We also report the detection of deuterium Balmer lines up to D$\delta$ (M16) and to D$\gamma$ (M20) in the blue wings of the hydrogen lines, which excitation mechanism seems to be continuum fluorescence. The temperature fluctuations paradigm agree with the results obtained from optical CELs and the more uncertain ones from far IR fine structure CELs in NGC 3603, although, more observations covering the same volume of the nebula are necessary to obtain solid conclusions.Comment: 22 pages, 13 Tables, 7 Figures. Accepted for publication by MNRA

Testing the Divergence Stack Memory on GPGPUs: A Modular in-Field Test Strategy

General Purpose Graphic Processing Units (GPGPUs) are becoming a promising solution in safety-critical applications, e.g., in the automotive domain. In these applications, reliability and functional safety are relevant factors in the selection of devices to build the systems. Nowadays, many challenges are impacting the implementation of high-performance devices, such as GPGPUs. Moreover, there is the need for effective fault detection solutions to guarantee the correct in-field operation of a GPGPU, such as in the branch management unit, which is one of the most critical modules in this parallel architecture. Faults affecting this structure can heavily corrupt or even collapse the execution of an application on the GPGPU. In this work, we propose a non-invasive Software-Based Self-Test (SBST) solution to detect faults affecting the memory in the branch management unit of a GPGPU. We propose a scalar and modular mechanism to develop the test program as a combination of software functions. The FlexGripPlus model was employed to evaluate the proposed strategies experimentally. Results show that the proposed strategies are effective to test the target structure and detect up to 98% of permanent faults. General Purpose Graphic Processing Units (GPGPUs) are becoming a promising solution in safety-critical applications, e.g., in the automotive domain. In these applications, reliability and functional safety are relevant factors in the selection of devices to build the systems. Nowadays, many challenges are impacting the implementation of high-performance devices, such as GPGPUs. Moreover, there is the need for effective fault detection solutions to guarantee the correct in-field operation of a GPGPU, such as in the branch management unit, which is one of the most critical modules in this parallel architecture. Faults affecting this structure can heavily corrupt or even collapse the execution of an application on the GPGPU. In this work, we propose a non-invasive Software-Based Self-Test (SBST) solution to detect faults affecting the memory in the branch management unit of a GPGPU. We propose a scalar and modular mechanism to develop the test program as a combination of software functions. The FlexGripPlus model was employed to evaluate the proposed strategies experimentally. Results show that the proposed strategies are effective to test the target structure and detect up to 98% of permanent faults

Biological, Molecular and Phiysiological Characterization of Four Soybean mosaic virus Isolates Present in Argentine Soybean Crops

Soybean mosaic virus (SMV) causes systemic infections in soybean plants, leading to chlorotic mosaic and producing significant yield losses. The virus is widely distributed in all soybean production areas in the world. In Argentina, three geographical isolates were identified: Marcos Juárez (MJ), Manfredi (M), and North Western Argentina (NOA), and another isolate named “Planta Vinosa” (PV), which causes severe necrosis symptoms in some cultivars. Here, the biological, molecular and physiological characterization of these isolates was performed for the first time. Three of the four isolates showed a low genetic divergence in the evaluated genes (P1, CI and CP). Although SMV-NOA and SMV-PV had high homology at the sequence level, they showed wide differences in pathogenicity, seed mottling and the ability of transmission by seeds or aphids, as well as in physiological effects. SMV-NOA caused early alterations (before symptom appearance, BS) in ΦPSII and MDA content in leaves with respect to the other isolates. After the appearance of macroscopic symptoms (late symptoms, LS), SMV-M caused a significant increase in the content of MDA, total soluble sugars, and starch with respect to the other isolates. Thus, early alterations of ΦPSII and soluble sugars might have an impact on late viral symptoms. Likewise, SMV-MJ developed more severe symptoms in the susceptible Davis cultivar than in DM 4800. Therefore, our results show differences in genome, biological properties and physiological effects among SMV isolates as well as different interactions of SMV-MJ with two soybean cultivars.Instituto de Patología VegetalFil: Maugeri Suarez, M. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales (FCEFyN); ArgentinaFil: Rodriguez, Marianela. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Fisiología y Recursos Genéticos Vegetales; ArgentinaFil: Rodriguez, Marianela. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Estudios Agropecuarios (UDEA) ; ArgentinaFil: Bejerman, Nicolas Esteban. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; ArgentinaFil: Bejerman, Nicolas Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); ArgentinaFil: Laguna, Irma Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); ArgentinaFil: Laguna, Irma Graciela. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; ArgentinaFil: Rodriguez Pardina, Patricia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; ArgentinaFil: Rodriguez Pardina, Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); Argentin

A striking property of recombinant poxviruses: Efficient inducers of in vivo expansion of primed CD8(+) T cells

CSIC, Ctr Nacl Biotecnol, Madrid 28049, SpainNYU, Sch Med, Dept Med & Mol Parasitol, New York, NY 10010 USAEscola Paulista Med, BR-04023 São Paulo, BrazilEscola Paulista Med, BR-04023 São Paulo, BrazilWeb of Scienc

An extended model to support detailed GPGPU reliability analysis

General Purpose Graphics Processing Units (GPGPUs) have been used in the last decades as accelerators in high demanding data processing applications, such as multimedia processing and high-performance computing. Nowadays, these devices are becoming popular even in safety-critical applications, such as autonomous and semi-autonomous vehicles. However, these devices can suffer from the effects of transient faults, such as those produced by radiation effects. These effects can be represented in the system as Single Event Upsets (SEUs) and are able to generate intolerable application misbehaviors in safety critical environments. In this work, we extended the capabilities of an open-source VHDL GPGPU model (FlexGrip) in order to study and analyze in a much more detailed manner the effects of SEUs in some critical modules within a GPGPU. Simulation results showed that scheduler controller has different levels of SEU sensibility depending on the affected location. Moreover, a reduced number of execution units, in the GPGPU can decrease the system reliability

Radio Continuum and Water Maser Observations of the High-Mass Protostar IRAS 19035+0641 A

We present Very Large Array (VLA) 1.3 cm continuum and 22.2 GHz H$_2$O maser observations of the high-mass protostellar object IRAS 19035+0641 A. Our observations unveil an elongated bipolar 1.3 cm continuum structure at scales $\lesssim500\,$au which, together with a rising in-band spectral index, strongly suggests that the radio emission toward IRAS 19035+0641 A arises from an ionized jet. In addition, eight individual water maser spots well aligned with the jet axis were identified. The Stokes V spectrum of the brightest H$_2$O maser line ($\sim100\,$Jy) shows a possible Zeeman splitting and is well represented by the derivatives of two Gaussian components fitted to the Stokes I profile. The measured $B_{\mathrm{los}}$ are $123\,(\pm27)$ and $156\,(\pm8)\,$mG, translating to a pre-shock magnetic field of $\approx7\,$mG. Subsequent observations to confirm the Zeeman splitting showed intense variability in all the water maser spots, with the brightest maser completely disappearing. The observed variability in a one-year time scale could be the result of an accretion event. These findings strengthen our interpretation of IRAS 19035+0641 A as a high-mass protostar in an early accretion/outflow evolutionary phase.Comment: 12 pages, 6 figures, ApJ accepte

Functional correlates of response inhibition in impulse control disorders in Parkinson’s disease

Impulse control disorder is a prevalent side-effect of Parkinson’s disease (PD) medication, with a strong negative impact on the quality of life of those affected. Although impulsivity has classically been associated with response inhibition deficits, previous evidence from PD patients with impulse control disorder (ICD) has not revealed behavioral dysfunction in response inhibition. In this study, 18 PD patients with ICD, 17 PD patients without this complication, and 15 healthy controls performed a version of the conditional Stop Signal Task during functional magnetic resonance imaging. Whole-brain contrasts, regions of interest, and functional connectivity analyses were conducted. Our aim was to investigate the neural underpinnings of two aspects of response inhibition: proactive inhibition, inhibition that has been prepared beforehand, and restrained inhibition, inhibition of an invalid inhibitory tendency. We observed that, in respect to the other two groups, PD patients with ICD exhibited hyperactivation of the stopping network bilaterally while performing proactive inhibition. When engaged in restrained inhibition, they showed hyperactivation of the left inferior frontal gyrus, an area linked to action monitoring. Restrained inhibition also resulted in changes to the functional co-activation between inhibitory regions and left inferior parietal cortex and right supramarginal gyrus. Our findings indicate that PD patients with ICD completed the inhibition task correctly, showing altered engagement of inhibitory and attentional areas. During proactive inhibition they showed bilateral hyperactivation of two inhibitory regions, while during restrained inhibition they showed additional involvement of attentional areas responsible for alerting and orientin

Chemical abundances of the Galactic H II region NGC 3576 derived from VLT echelle spectrophotometry

We present echelle spectrophotometry of the Galactic H II region NGC 3576. The data have been taken with the VLT UVES echelle spectrograph in the 3100 to 10400 angstroms range. We have measured the intensities of 458 emission lines, 344 are permitted lines of H0, He0, C+, N0, N+, N++, O0, O+, Ne+, S++, Si0, Si+, Ar0 and Ar+; some of them are produced by recombination and others mainly by fluorescence. Electron temperatures and densities have been determined using different continuum and line intensity ratios. We have derived He+, C++, O+, O++ and Ne++ ionic abundances from pure recombination lines. We have also derived abundances from collisionally excited lines for a large number of ions of different elements. Remarkably consistent estimations of t2 have been obtained by comparing Balmer and Paschen to [O III] temperatures, and O++ and Ne++ ionic abundances obtained from collisionally excited and recombination lines. The chemical composition of NGC 3576 is compared with those of other Galactic H II regions and with the one from the Sun. A first approach to the gas-phase Galactic radial abundance gradient of C as well as of the C/O ratio has been made.Comment: 25 pages, 14 tables, 4 figures. Accepted for publication in ApJ