4,871 research outputs found
Community college students\u27 plant biodiversity learning experience in an introductory biology course: exploring the value added by using a CD-ROM to develop inquiry lessons
This study examined the value added to standard textbook-based instruction of plant biodiversity by the use of the exemplary interactive CD-ROM, Conserving Earthâs Biodiversity. This CD-ROM features renowned conservation figure E.O. Wilson. The setting of the research was an introductory biology course in a rural public community college in the Deep South. Six participants were purposively selected to represent three levels of achievement and two groups, the CD-ROM group (exposed to CD-ROM in addition to the textbook) and the textbook group (only course textbook). Students experienced lecture-based, textual, virtual, and real experiences, and examined their ability to understand biodiversity-related concepts and to pursue guided-inquiry questions about local plant biodiversity. Their performance was assessed through activities, quizzes, concept maps, interviews, surveys, and studentsâ presentations. This study led to three main findings. First, use of the CD-ROM, in addition to the textbook, allowed students to form a well-rounded grasp of plant biodiversity. Second, use of the CD-ROM enhanced the development of inquiries on local plant biodiversity and the metacognitive phase of assigning roles for local plant diversity. Third, the Plant Biodiversity Literacy Rubric [PBLR] was developed, based upon the history of the concept of biodiversity and was used to evaluate studentsâ progress by assigning them to various levels of understanding during the study. The students in the CD-ROM group gained a broader perspective of plant biodiversity-related concepts, such as levels of biodiversity, hot spots, genetic diversity, food plant diversity, and threats to biodiversity. The CD-ROM was never detrimental to the learning process. They were more self-directed in their development of inquiries, felt more confident about their presentations, and were more metacognitive during their inquiries. Performance on specific activities such as the essay and The Golden List of Species suggested an enhanced cognitive-behavioral/affective experience for students in the CD-ROM group. The PBLR is an exportable instrument, which may allow ecology educators at all levels to assess studentâs levels of understanding in a sensitive way. At this time, it is critical to gauge effective understanding of plant biodiversity and ecology education, as it is vital to the survival and well-being of life on Earth
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Triage and Ongoing Care for Critically Ill Patients in the Emergency Department: Results from a National Survey of Emergency Physicians
Introduction: We conducted a cross-sectional study at the Icahn School of Medicine at Mount Sinai to elicit emergency physician (EP) perceptions regarding intensive care unit (ICU) triage decisions and ongoing management for boarding of ICU patients in the emergency department (ED). We assessed factors influencing the disposition decision for critically ill patients in the ED to characterize EPsâ perceptions about ongoing critical care delivery in the ED while awaiting ICU admission.Methods: Through content expert review and pilot testing, we iteratively developed a 25-item written survey targeted to EPs, eliciting current ICU triage structure, opinions on factors influencing ICU admission decisions, and views on caring for critically ill patients âboardingâ in the ED for >4-6 hours.Results: We approached 732 EPs at a large, national emergency medicine conference, achieving 93.6% response and completion rate, with 54% academic and 46% community participants. One-fifth reported having formal ICU admission criteria, although only 36.6% reported adherence. Common factors influencing EPsâ ICU triage decisions were illness severity (91.1%), ICU interventions needed (87.6%), and diagnosis (68.2%), while ICU bed availability (13.5%) and presence of other critically ill patients in ED (10.2%) were less or not important. While 72.1% reported frequently caring for ICU boarders, respondents identified high patient volume (61.3%) and inadequate support staffing (48.6%) as the most common challenges in caring for boarding ICU patients.Conclusion: Patient factors (eg, diagnosis, illness severity) were seen as more important than system factors (eg, bed availability) in triaging ED patients to the ICU. Boarding ICU patients is a common challenge for more than two-thirds of EPs, exacerbated by ED volume and staffing constraints
Extended mean-variance model for reliable evolutionary portfolio optimization
Real world optimization of financial portfolios pose a challenging multiobjective problem that can be tackled using Evolutionary Algorithms. The fact that the optimization process is subject to the presence of uncertainty concerning asset returns is likely to lead to unreliable solutions. This work suggests extending the classic mean-variance optimization problem with a third explicit robustness objective. This results on sets of portfolios that can be subsequently grouped together according to their reliability. This additional information allows for a better informed decision making regarding asset allocation. © 2014 - IOS Press and the authors. All rights reserved.Financial support granted by the Spanish Ministry of Science under contract TIN2011-28336 (MOVES)
Moisture AïŹnity of HDPE/Phase-Change Material Composites for Thermal Energy Storage Applications
Moisture adsorption can degrade the structural integrity of thermal energy storage devices and can negatively impact the capacity and charging/discharging behavior. Steady-state and transient experiments are conducted at various operating temperatures to evaluate the moisture aïŹnity of organic phase-change material (PCM) shape stabilized with high-density polyethylene (HDPE)
Novel method of severe plastic deformation - Continuous closed die forging: CP aluminum case study
There is a
large number of methods for severe plastic deformation (SPD).
Multidirectional forging (MDF) is probably one of the most easily scalable for industrial
application. In general, two main conditions
need to be fulfilled
for
successful
SPD processing:
constan
t sample geometry and application of a quasi
-
hydrostatic pressure. The first condition is
necessary for strain accumulation by repetitive deformation and the second one helps preventing
cracking in the specimens with high accumulated strain. However, MDF i
s not providing quasi
-
hydrostatic condition in the processed sample. This paper reports a novel method for severe plastic
deformation, namely continuous close
d
die forging (CCDF), which fulfils both requirements for the
successful deformation of samples to
a very high accumulated strain. Commercially pure aluminum
(1050) was processed to a total strain of 24 by CCDF. After processing, the microstructure was
refined down to a mean grain size of
0.
78
”m
.
Tensile testing showed good mechanical properties:
yiel
d strength and ultimate tensile strength of the ultrafine
-
grained
(UFG)
aluminum were 180 and
226 MPa, respectively. Elongation to rupture was about 18%. The microstructure, microhardness
and grain boundary statistics are discussed
with regard
to the high
mechanical properties of the
UFG aluminum processed by th
is
novel method.Peer ReviewedPostprint (author's final draft
Collaboration of Researchers and Stakeholders: Transforming Educator Preparation
This study contributes to the literature on first year teachers by identifying complexities and struggles of becoming a teacher and the implications of district-university partnerships to strengthen our educator preparation program. The importance of partnerships with stakeholders, memorandum of agreements to share data, observations of first year teachers by university faculty, employer surveys, and the first year teacherâs perspectives about how well our university prepared them, as well as how they compare with other first year teachers nationally is addressed. Multiple sources of data were used to provide information about completers, individuals that graduated from the educator preparation program. These include state reports, national trends, and review of survey results next to universities across the United States involved in teacher preparation. Graduates of our teacher preparation program have a 93% retention rate after five years of teaching. The national average is 50% after five years
Reducing Poverty in CaliforniaâŠPermanently
If California were to seriously commit to equalizing opportunity and reducing poverty, how might that commitment best be realized?
This is of course a hypothetical question, as there is no evidence that California is poised to make such a serious commitment, nor have many other states gone much beyond the usual lip-service proclamations. There are many reasons for Californiaâs complacency, but an important one is that most people think that poverty is intractable and that viable solutions to it simply donât exist.
When Californians know what needs to be done, they tend to go forward and get it done. When, for example, the stateâs roads are in disrepair, there are rarely paralyzing debates about exactly how to go about fixing them; instead we proceed with the needed repairs as soon as the funds to do so are appropriated. The same type of sure and certain prescription might appear to be unavailable when it comes to reducing poverty. It is hard not to be overwhelmed by the cacophony of voices yielding a thick stream of narrow-gauge interventions, new evaluations, and piecemeal proposals.1
Although the research literature on poverty is indeed large and may seem confusing, recent advances have in fact been so fundamental that it is now possible to develop a science-based response to poverty. In the past, the causes of poverty were not well understood, and major interventions, such as the War on Poverty, had to be built more on hunch than science. It is an altogether different matter now. The causes of poverty are well established, and the effects of many possible policy responses to poverty are likewise well established. The simple purpose of this essay is to assemble these advances into a coherent plan that would, if implemented, reduce poverty in California substantially
Effect of nacl replacement by other salts on the quality of bĂsaro pork sausages (Pgi chouriça de vinhais)
Concerned about the trend to reduce salt consumption, the meat industry has been increasing the strategies to produce and commercialize products where the reduction or even the replacement of NaCl is an important goal. The aim of this study was to test the effect of partial NaCl replacement by KCl and Sub4SaltÂź on the quality of pork sausages. Three different formulations (NaCl + KCl, NaCl + Sub4SaltÂź, and KCl + Sub4SaltÂź) were considered and compared to the control (2% NaCl). Physicochemical properties, chemical composition, and microbiological and sensory characteristics were evaluated. The replacement of NaCl did not affect pH, water activity (aw) or its chemical composition after eight or 16 days ripening time, while a significant sodium reduction was achieved. The oxidation index expressed in TBARS was also not affected by the NaCl substitution and varied between 0.01 to 0.04 of malonaldehyde (MDA) per kg of sample. Similarly, the NaCl replacement did not change the microbiological quality of the sausages, and the production of healthier meat sausages had also no significant effect on their sensory characteristics. Therefore, according to the results obtained, it is viable and a good strategy for the meat industry to produce âreduced sodium contentâ sausages without affecting their traditional quality.The authors are grateful to the Foundation for Science and Technology (FCT,
Portugal) for financial support by national funds FCT/MCTES to CIMO (UIDB/00690/2020); to
BĂsaro-Salsicharia Tradicional industry and to Laboratory of Carcass and Meat Quality of Agriculture
School of Polytechnic Institute of Bragança âCantinho do Alfredoâ. Thanks are extended to GAIN
(Axencia Galega de InnovaciĂłn) for supporting this work (grant number IN607A2019/01). The
authors are members of the Healthy Meat network, funded by CYTED (ref. 119RT0568).info:eu-repo/semantics/publishedVersio
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Striatal transcriptome of a mouse model of ADHD reveals a pattern of synaptic remodeling
Despite the prevalence and high heritability of Attention-Deficit/Hyperactivity Disorder (ADHD), genetic etiology remains elusive. Clinical evidence points in part to reduced function of the striatum, but which specific genes are differentially expressed and how they sculpt striatal physiology to predispose ADHD are not well understood. As an exploratory tool, a polygenic mouse model of ADHD was recently developed through selective breeding for high home cage activity. Relative to the Control line, the High-Active line displays hyperactivity and motor impulsivity which are ameliorated with amphetamine. This study compared gene expression in the striatum between Control and High-Active mice to develop a coherent hypothesis for how genes might affect striatal physiology and predispose ADHD-like symptoms. To this end, striatal transcriptomes of High-Active and Control mice were analyzed after mice were treated with saline or amphetamines. The pseudogene Gm6180 for n-cofilin (Cfl1) displayed 20-fold higher expression in High-Active mice corresponding with reduced Cfl1 expression suggesting synaptic actin dysregulation. Latrophilin 3 (Lphn3), which is associated with ADHD in human populations and is involved in synapse structure, and its ligand fibronectin leucine rich transmembrane protein 3 (Flrt3), were downregulated in High-Active mice. Multiple genes were altered in High-Active mice in a manner predicted to downregulate the canonical Wnt pathway. A smaller and different set of genes including glyoxalase (Glo1) were differentially regulated in High-Active as compared to Control in response to amphetamine. Together, results suggest genes involved in excitatory synapse regulation and maintenance are downregulated in ADHD-like mice. Consistent with the molecular prediction, stereological analysis of the striatum from a separate set of mice processed for imunohistochemical detection of synaptophysin revealed approximately a 46% reduction in synaptophysin immunoreactivity in High-Active relative to Control. Results provide a new set of molecular targets related to synapse maintenance for the next generation of ADHD medicines
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