Estudio de factibilidad para la ampliación de la capacidad productiva de planta de galvanizado en caliente

Analiza el potencial actual de operaciones de la empresa metalmecánica Galva SAC, que por confidencialidad se denominará así a la organización del estudio, es una unidad de negocio del galvanizado por inmersión en caliente. Evalúa el entorno económico del mercado con respecto a la oferta y demanda de dicho servicio, esto dará la factibilidad de instalar una nueva planta en Lurín con mayor capacidad de producción y equipos de última generación, así como repotenciar la estructura organizacional. El análisis se fundamenta en estudios de mercado enfocados en la industria metalmecánica, en las tendencias del consumidor y en el servicio. Este modelo puede servir de guía a los directivos y funcionarios de la compañía metalmecánica en la toma de decisiones de reestructuración de su volumen productivo, utilizando herramientas de análisis y propuestas enfocadas a la expansión de la unidad de negocio.Trabajo de suficiencia profesiona

Characterization of Mouse Ms4a4a and Ms4a6d Antibodies

https://openworks.mdanderson.org/sumexp23/1041/thumbnail.jp

Identifying Parkinson’s disease subtypes with motor and non-motor symptoms via model-based multi-partition clustering

Identification of Parkinson's disease subtypes may help understand underlying disease mechanisms and provide personalized management. Although clustering methods have been previously used for subtyping, they have reported generic subtypes of limited relevance in real life practice because patients do not always fit into a single category. The aim of this study was to identify new subtypes assuming that patients could be grouped differently according to certain sets of related symptoms. To this purpose, a novel model-based multi-partition clustering method was applied on data from an international, multi-center, cross-sectional study of 402 Parkinson's disease patients. Both motor and non-motor symptoms were considered. As a result, eight sets of related symptoms were identified. Each of them provided a different way to group patients: impulse control issues, overall non-motor symptoms, presence of dyskinesias and pyschosis, fatigue, axial symptoms and motor fluctuations, autonomic dysfunction, depression, and excessive sweating. Each of these groups could be seen as a subtype of the disease. Significant differences between subtypes (P< 0.01) were found in sex, age, age of onset, disease duration, Hoehn & Yahr stage, and treatment. Independent confirmation of these results could have implications for the clinical management of Parkinson's disease patients.F.R.-S., C.B., and P.L. are supported in part by the Spanish Ministry of Economy and Competitiveness through the PID2019-109247GB-I00 project, by the European Union’s Horizon 2020 Framework Programme for Research and Innovation under the Specific Grant Agreement No. 945539 (Human Brain Project SGA3), and by the BBVA Foundation (2019 Call) through the ”Score-based nonstationary temporal Bayesian networks. Applications in climate and neuroscience” project.S

Elaboración de productos de higiene y desinfección en los laboratorios de ciencias de la URACCAN en el contexto COVID-19

Within the context of the pandemic caused by the spread of COVID-19 where there is no specific treatment, nor a vaccine for prevention, so the best way is to avoid being exposed to the virus. It is then necessary to comply with the disinfection and control measures that have been shown to minimize the chances of contagion or infection. In this process, the present experimental work was developed, in the Science Laboratory of the University of the Autonomous Regions of the Nicaraguan Caribbean Coast (URACCAN), Nueva Guinea Campus, with the purpose of developing hygiene, cleaning and disinfection supplies, obtaining as results, solid soap, 4% sodium hypochlorite and 70% ethyl alcohol. Based on the foregoing, these products are considered as a sustainable alternative to fight against the disease, with the perspective of reducing acquisition costs and ensuring their availability for the university community.Dentro del marco de la pandemia originada por el contagio del COVID-19, hasta la fecha no existe un tratamiento específico, ni una vacuna para la prevención, por lo que la mejor manera es evitar exponerse al virus. Es necesario entonces, cumplir con las medidas de desinfección y control que han demostrado minimizar las probabilidades de contagio o infección. En este marco, se desarrolló el presente trabajo experimental, en el Laboratorio de Ciencia de la Universidad de las Regiones Autónomas de la Costa Caribe Nicaragüense (URACCAN), Recinto Nueva Guinea, con el propósito de elaborar insumos de higiene, limpieza y desinfección, obteniéndose como resultados, jabón sólido, hipoclorito de sodio al 4% y alcohol etílico al 70%. Con base a lo anterior, estos productos son considerados como una alternativa sostenible de lucha frente a la enfermedad, con la perspectiva de disminuir los costos de adquisición y asegurar la disponibilidad de los mismos para la comunidad universitaria

A High Resolution Radio Survey of Class I Protostars

We report the results of a survey of low mass Class I protostars in the cm continuum. In the initial survey, seven sources in the Taurus star formation were observed with the VLA at 0``.25 resolution. All seven sources drive CO outflows and display Herbig-Haro flows in the optical or near infrared wavebands. 4/7 sources were detected, two of which are new discoveries in systems of very low luminosity, one being the lowest luminosity system detected to date in the cm continuum. Notably, three sources were not detected to a 3-sigma limit of 0.10 mJy/beam, which indicates that significant cm continuum emission is not a universal feature of Class I systems with outflow activity. Subsequent observations of HH30, a more evolved Class II system, found no emission to a 3-sigma limit of 0.03 mJy/beam. After comparison with near infrared data, we suggest that the discriminating feature of the detected systems is a relatively high ionisation fraction in the stellar wind. Temporal variability of the outflow may also play a role. The one relatively bright source, IRAS 04016+2610 (L1489 IRS), is clearly resolved on a 0``.4 scale at 2 cm and 3.5 cm. Follow-up imaging with MERLIN did not detect this source with a 0``.04 beam, indicating that the radio emission is generated in a region with a radius of about 25 au, which is broadly similar to the radius of the bipolar cavities inferred from models of near infrared data. Interpretation of this system is complicated by the existence of a quadrupolar outflow, which we originally detected through polarimetric imaging. We present a near infrared H2 image in which a bow shock in the secondary outflow is clearly seen. This complicated structure may have been caused by a gravitational interaction between two protostars.Comment: Accepted by MNRAS. 16 pages, 5 figures, 9 postscript files, 1 Latex fil

(E)-2-[(2-Hydr­oxy-5-nitro­phen­yl)iminiometh­yl]phenolate

In the title mol­ecule, C13H10N2O4, the dihedral angle between the mean planes of the benzene and phenolate rings is 21.6 (4)°. The nitro O atoms are twisted slightly out of the plane of the ring to which the nitro group is attached [dihedral angle 8.4 (3)°]. The amine group forms an intra­molecular hydrogen bond with both nearby O atoms. An extended π delocalization throughout the entire mol­ecule exists producing a zwitterionic effect in this region of the mol­ecule. The shortened C—O bond [1.2997 (15) Å] in concert with the slightly longer C—OH bond [1.3310 (16) Å] provide evidence for this effect. The crystal packing is influenced by strong inter­molecular O—H⋯O hydrogen bonding. As a result, mol­ecules are linked into an infinite zigzag chain running along the b axis. A MOPAC PM3 calculation provides support to these observations

Non-Thermal Plasma Activation of Gold-Based Catalysts for Low-Temperature Water-Gas Shift Catalysis

Acknowledgements The UK Catalysis Hub is kindly thanked for resources and support provided via our membership of the UK Catalysis Hub Consortium and funded by EPSRC (Portfolio Grants EP/K014706/2, EP/K014668/1, EP/K014854/1, EP/K014714/1, and EP/I019693/1). Open access data can be found via the University of Manchester research portal. We are grateful to Helen Daly (Queen's University Belfast) for discussion, to Fabio de Rosa (Queen's University Belfast) for the thermodynamic equilibrium calculations (obtained using the Convergence tool of Aspen Plus 8.0) and to Emma Gibson (Harwell Research Complex) for the BET measurements. JJ Delgado is grateful to Ramon y Cajal program and the Ce-NanoSurPhases project grant from MINECO.Peer reviewedPostprintPostprintPublisher PD