75 research outputs found

    Estrategias docentes para la formación de alumnos extranjeros en la Universidad de Burgos

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    There are many foreign students who choose our country to perfect their studies, doing exchanges with Spanish Universities. Annually, University of Burgos hosts students from different countries, specially from the United Mexican States. The agreements between University of Burgos and Mexican University of Baja California, San Luis Potosi, Chihuahua or Mexico City have enabled that many students of the Architecture School take subjects of Building Engineering Degree and Roads, Canals and Ports Engineer Degree. This paper develops a training strategy that professors of the subject of Prevention and Building Safety, which is part of the Building Engineering Degree, have been implemented with the aim to perfect the knowledge of this discipline in visitor’s students from School of Architecture of the United Mexican States.Son muchos los alumnos extranjeros que eligen nuestro país para perfeccionar su formación universitaria, realizando intercambios con Universidades Españolas. La Universidad de Burgos recibe anualmente alumnos de diferentes países, entre los que destacan los procedentes de los Estados Unidos Mexicanos. Los acuerdos entre la Universidad de Burgos y las Universidad Mexicanas de los Estados de Baja California, San Luis Potosí, Chihuahua o México D.F. han posibilitado que muchos alumnos de las Facultades de Arquitectura cursen asignaturas de las Titulaciones de Ingeniería de Edificación e Ingeniería de Caminos Canales y Puertos. En este artículo se desarrolla una estrategia formativa que los profesores de la asignatura de Prevención y Seguridad en la Construcción, de la Titulación de Ingeniería de Edificación, han puesto en práctica, con el objetivo me perfeccionar el conocimiento de esta disciplina en los alumnos visitantes de las Escuelas de Arquitectura de los Estados Unidos Mexicanos

    Integración de la prevención de riesgos laborales en las pymes del sector de la construcción

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    La integración de la prevención de riesgos laborales en el sistema general de gestión de la empresa es un factor estratégico para garantizar la seguridad y salud de los trabajadores, siendo muchas las dificultades que surgen en el proceso de integración de la prevención en la estructura de gestión de la empresa, por lo que es determinante conocer las causas que lo impiden, especialmente en aquellos sectores con mayor siniestralidad, y poder introducir así los ajustes necesarios para conseguir sistemas preventivos eficaces. El presente trabajo de investigación tiene como principal objetivo determinar las causas específicas que dificultan la integración de la prevención en el sector de la construcción, que por sus singulares características se posiciona como uno de los sectores con mayor siniestralidad laboral y con importantes carencias desde el punto de vista preventiv

    Patient-Tailored In Silico 3D Simulations and Models From Electroanatomical Maps of the Left Atrium

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    Proceeding of 2018 Computing in Cardiology Conference (CinC), September 23-26, 2018, Maastricht, The NetherlandsThe mechanisms underlying atrial fibrillation (AF) are still under debate, making treatments for this arrhythmia remain suboptimal, with most treatments applied in a standard fashion with no patient personalization. Recent technological advances in electroanatomical mapping (EAM) using multi-electrode catheter allow the physicians to better characterize the substrate, thanks to a better spatial resolution and higher density of acquisition points. Taking advantage of this technology, we describe a workflow to build personalized electrophysiological atrial models for AF patients. We seek to better predict the outcome of a treatment and study the AF problem in a more specific scenario. We generated physiological 3D models from the EAM data using hexahedral meshing of element size 300μm, and added fiber orientation based on a generic model. We used the local activation time (LAT) maps performed in sinus rhythm (SR) to estimate the conduction velocity (CV) of the regions in the atrium with a new method that combines the LATs of neighboring tissue as the average CV of triplets of points. We also characterized the cellular model by Maleckar et al. in terms of longitudinal conductivity and CV to personalize the atrial models. We were able to simulate SR and AF scenarios on the personalized models, and we generated a database of atrial models for future analysis.This work has been partly supported by MINECO/FEDER (ADVENTURE, id. TEC2015-69868-C2-1-R), Co munidad de Madrid (CASI-CAM-CM, id. S2013/ICE-2845), Centro de Investigación Biomédica en Red (CIBER), proyecto DPI2016-75458, and the Programa Prometeo, Generalitat Valenciana, Award Number: 2016/088.Publicad

    Glutatión peroxidasas y tiorredoxinas en la leguminosa modelo Lotus japonicus

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    Las leguminosas constituyen una familia de plantas de gran importancia agronómica y ecológica. En simbiosis con bacterias del suelo, denominadas rizobios, llevan a cabo la fijación biológica de nitrógeno, que genera gran cantidad de especies reactivas de oxígeno y nitrógeno. Para mantenerlas en concentraciones óptimas, las células vegetales contienen metabolitos y enzimas antioxidantes. Entre ellas, las glutation peroxidasas y las tiorredoxinas desempeñan un importante papel en la percepción, integración y transmisión de señales redox y en la protección frente al daño oxidativo en condiciones de estrés. Esta tesis aporta nueva información sobre la función de las glutation peroxidasas y las tiorredoxinas en la simbiosis rizobio-leguminosa

    Optimisation of ultrasound liver perfusion through a digital reference object and analysis tool

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    [EN] Background Conventional ultrasound (US) provides important qualitative information, although there is a need to evaluate the influence of the input parameters on the output signal and standardise the acquisition for an adequate quantitative perfusion assessment. The present study analyses how the variation in the input parameters influences the measurement of the perfusion parameters. Methods A software tool with simulator of the conventional US signal was created, and the influence of the different input variables on the derived biomarkers was analysed by varying the image acquisition configuration. The input parameters considered were the dynamic range, gain, and frequency of the transducer. Their influence on mean transit time (MTT), the area under the curve (AUC), maximum intensity (MI), and time to peak (TTP) parameters as outputs of the quantitative perfusion analysis was evaluated. A group of 13 patients with hepatocarcinoma was analysed with both a commercial tool and an in-house developed software. Results The optimal calculated inputs which minimise errors while preserving images¿ readability consisted of gain of 15¿dB, dynamic range of 60¿dB, and frequency of 1.5¿MHz. The comparison between the in-house developed software and the commercial software provided different values for MTT and AUC, while MI and TTP were highly similar. Conclusion Input parameter selection introduces variability and errors in US perfusion parameter estimation. Our results may add relevant insight into the current knowledge of conventional US perfusion and its use in lesions characterisation, playing in favour of optimised standardised parameter configuration to minimise variability.Alberich-Bayarri, Á.; Tomás-Cucarella, J.; Torregrosa-Lloret, A.; Saiz Rodríguez, FJ.; Martí-Bonmatí, L. (2019). Optimisation of ultrasound liver perfusion through a digital reference object and analysis tool. European Radiology Experimental. 3:1-10. https://doi.org/10.1186/s41747-019-0086-5S1103Parker JM, Weller MW, Feinstein LM et al (2013) Safety of ultrasound contrast agents in patients with known or suspected cardiac shunts. Am J Cardiol 112:1039–1045.Dhamija E, Paul SB (2014) Role of contrast enhanced ultrasound in hepatic imaging. Trop Gastroenterol 35:141–151.Wang XY, Kang LK, Lan CY (2014) Contrast-enhanced ultrasonography in diagnosis of benign and malignant breast lesions. Eur J Gynaecol Oncol 35:415–420.Wang S, Yang W, Zhang H, Xu Q, Yan K (2015) The role of contrast-enhanced ultrasound in selection indication and improveing diagnosis for transthoracic biopsy in peripheral pulmonary and mediastinal lesions. Biomed Res Int 2015:231782.Green MA, Mathias CJ, Willis LR, et al (2007) Assessment of Cu-ETS as a PET radiopharmaceutical for evaluation of regional renal perfusion. Nucl Med Biol 34:247–255.Daghini E, Primak AN, Chade AR, et al (2007) Assessment of renal hemodynamics and function in pigs with 64-section multidetector CT: comparison with electron-beam CT. Radiology 243:405–412.Martin DR, Sharma P, Salman K, et al (2008) Individual kidney blood flow measured with contrast-enhanced first-pass perfusion MR imaging. Radiology 246:241–248.Tang MX, Mulvana H, Gauthier T, et al (2011) Quantitative contrast-enhanced ultrasound imaging: a review of sources of variability. Interface Focus 1:520–539.Gauthier TP, Averkiou MA, Leen EL (2011) Perfusion quantification using dynamic contrast-enhanced ultrasound: the impact of dynamic range and gain on time-intensity curves. Ultrasonics 51:102–106.Möller I, Janta I, Backhaus M, et al (2017) The 2017 EULAR standardised procedures for ultrasound imaging in rheumatology. Ann Rheum Dis. 76:1974–1979.Pitre-Champagnat S, Coiffier B, Jourdain L, Benatsou B, Leguerney I, Lassau N (2017) Toward a standardization of ultrasound scanners for dynamic contrast-enhanced ultrasonography: methodology and phantoms. Ultrasound Med Biol. https://doi.org/10.1016/j.ultrasmedbio.2017.06.032Shunichi S, Hiroko I, Fuminori M, Waki H (2009) Definition of contrast enhancement phases of the liver using a perfluoro-based microbubble agent, perflubutane microbubbles. Ultrasound Med Biol 35:1819–1827. doiFairbank WM Jr, Scully MO (1977) A new noninvasive technique for cardiac pressure measurement: resonant scattering of ultrasound from bubbles. IEEE Trans Biomed Eng 24:107–110.Malm S, Frigstad S, Helland F, Oye K, Slordahl S, Skjarpe T (2005) Quantification of resting myocardial blood flow velocity in normal humans using real-time contrast echocardiography. A feasibility study. Cardiovasc Ultrasound 3:16.Arditi M, Frinking PJ, Zhou X, Rognin NG (2006) A new formalism for the quantification of tissue perfusion by the destruction-replenishment method in contrast ultrasound imaging. IEEE Trans Ultrason Ferroelectr Freq Control 53:1118–1129.Savic RM, Jonker DM, Kerbusch T, Karlsson MO (2007) Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies. J Pharmacokinet Pharmacodyn 34:711–726.Averkiou M, Lampaskis M, Kyriakopoulou K, et al (2010) Quantification of tumor microvascularity with respiratory gated contrast enhanced ultrasound for monitoring therapy. Ultrasound Med Biol 36:68–77.Kuenen MP, Mischi M, Wijkstra H (2011) Contrast-ultrasound diffusion imaging for localization of prostate cancer. IEEE Trans Med Imaging 30:1493–1502.Garcia D, Le Tarnec L, Muth S, Montagnon E, Porée J, Cloutier G(2013) Stolt’s f-k migration for plane wave ultrasound imaging. IEEE Trans Ultrason Ferroelectr Freq Control 60:1853–1867.Brands J, Vink H, Van Teeffelen JW (2011) Comparison of four mathematical models to analyze indicator-dilution curves in the coronary circulation. Med Biol Eng Comput 49:1471–1479.Zhou JH, Cao LH, Zheng W, Liu M, Han F, Li AH (2011) Contrast-enhanced gray-scale ultrasound for quantitative evaluation of tumor response to chemotherapy: preliminary results with a mouse hepatoma model. AJR Am J Roentgenol 196:W13-17.Wei K, Jayaweera AR, Firoozan S, Linka A, Skyba DM, Kaul S (1998) Quantification of myocardial blood flow with ultrasoundinduced destruction of microbubbles administered as a constant venous infusion. Circulation 97:473–483Riascos P, Velasco-Medina J (2005) Efectos Biológicos y Consideraciones de Seguridad en Ultrasonido. 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    Production, cellular structure and thermal conductivity of microcellular (methyl methacrylate)–(butyl acrylate)–(methyl methacrylate) triblock copolymers.

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    Microcellular foaming of a (methyl methacrylate)–(butyl acrylate)–(methyl methacrylate) triblock copolymer was carried out by means of supercritical CO2 in a single-step process. The experiments were performed at 40 °C using a pressure of 300 bar (30 MPa) during 24 h. The depressurization times were modified from 2 to 30 min, leading to cell sizes from 10 to 100 µm, and relative densities from 0.11 to 0.17. It was found that the key parameter to control cell size and density was depressurization time: longer depressurization times generated larger cell sizes and lower densities. The thermal conductivity of these materials was measured using the transient plane source technique, and it was found that this decreased as the density was reduced. Various models for the prediction of thermal conductivity by conduction were tested. It was found that all the models underestimated the experimental results due to a significant contribution of radiation heat flow for these material

    Amplificador RF pulsado sobre tecnología LDMOS de alta tensión

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    In this paper, a high-voltage LDMOS-based RF pulsed power amplifier is presented. In a secondary radar transponder, the transmitter stage has to modulate the RF reply signal with the coded pulsed data while also amplifying it. Here, this desired behaviour is achieved thanks to the use of high level drain modulation over a novel 50 V LDMOS technology. A 63.24 % DC power efficiency at a 10 W output power level has been measured, with a more than 40 dB ON-OFF ratio under 128 μs and 2% pulse conditions

    Applied research to new construction materials subject

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    [EN] The degree in Building Engineering at the University of Burgos has been included the Bologna System 10 years ago, implemented simultaneously in the 2010-2011 academic year the entire degree - four courses. According with the initial strategies, the acquisition of competences through project research work in the construction materials subjects has been one of the elements developed and consolidated, especially in the elective subjects of higher courses where training of the student already allows this type of resources. However, the work begins the first year with specific classes to introduce the investigation within the subjects of construction materials, with agenda reflected in the educational guide. One of them, for example, is an intensive course of advanced searches in international scientific databases, which must be used in a practical way to test what has been learned, and which can be extrapolated to the rest of the subjects of the degree.[ES] El grado en Arquitectura Técnica de la Universidad de Burgos lleva un recorrido de 10 años en el Plan Bolonia, que implantó de manera simultánea en el curso 2010-2011 para los cuatro cursos del grado. Dentro de las estrategias iniciales del Grado, la adquisición de competencias a través del trabajo por proyectos en las asignaturas de materiales de construcción ha sido uno de los factores que se ha desarrollado y afianzado, especialmente en la asignaturas optativas de cursos más altos donde la formación del estudiante ya permite este tipo de recursos. No obstante, se comienza desde primer curso con clases específicas de introducción a la investigación dentro de las asignaturas de materiales de construcción, con temario contemplado en la guía docente. Una de ellas, por ejemplo, es un curso intensivo de búsquedas avanzadas en bases de datos científicas internacionales, que debe ser utilizado de manera práctica para poner a prueba lo aprendido, y que puede ser extrapolado al resto de asignaturas de la titulación.Gadea Sáinz, J.; Calderón Carpintero, V.; Junco Petrement, C.; Gutiérrez-González, S.; Rodríguez Saiz, Á.; Garabito López, J. (2021). Investigación aplicada a la formación en nuevos materiales de construcción. Editorial Universitat Politècnica de València. 37-43. https://doi.org/10.4995/EDIFICATE2021.2021.13531OCS374

    119Sn Mössbauer Spectroscopy for assessing the local stress and defect state towards the tuning of Ni-Mn-Sn alloys

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    [EN] The influence of defects and local stresses on the magnetic properties and martensitic transformation in Ni50Mn35Sn15 is studied at macroscopic and atomic scale levels. We show that both the structural and magnetic properties of the alloy are very sensitive to slight microstructural distortions. Even though no atomic disorder is induced by milling, the antiphase boundaries linked to dislocations promote the antiferromagnetic coupling of Mn, resulting in a significant decrease in the saturation magnetization. On the other hand, the temperature range of the transformation is considerably affected by the mechanically induced local stresses, which in turn does not affect the equilibrium temperature between the austenitic and martensitic phases. Finally, we demonstrate that the recovery of the martensitic transformation is directly related to the intensity of the non-magnetic component revealed by 119Sn Mössbauer spectroscopy. This result opens the possibility of quantifying the whole contribution of defects and the local stresses on the martensitic transformation in Ni-Mn-Sn alloys.This work was supported for the Basque Government Grant No. IT-1005-16 by the Spanish Ministry of Economy and Competitiveness under the project MAT2015-65165-C2- R (MINECO/FEDER) and GIC1585. I. Unzueta also wants to acknowledge the Basque Government Grant No. PRE2014-1-214. ILL and SpINS are acknowledged for beam time allocation. J. Lopez-Garcıa acknowledges ILL for his Ph.D. contract
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