Lipid Oxidation Inhibition in Frozen Farmed Salmon (Oncorhynchus kisutch ): Effect of Packaging

3 pages, 1 table.Coho salmon (Oncorhynchus kisutch) has recently attracted a great interest as a farmed product. This research focuses on its commercialisation as a frozen product. For it, an advanced storage technology combining vacuum and a polyphenolic rich-film was applied for a 9-months storage period (–18°C). The study was addressed to lipid hydrolysis and oxidation changes and to endogenous antioxidant content in salmon muscle. No effect of packaging conditions could be observed on free fatty acid formation. However, vacuum packaging conditions provided a partial inhibition of primary (peroxide) and secondary (anisidine value) lipid oxidation development; this inhibitory effect was accompanied by a lower tocopherol isomers loss. The employment of a film including polyphenolic compounds led to a partial inhibition of α-tocopherol breakdown and to a lower secondary (anisidine value) and tertiary (fluorescent compound formation) lipid oxidation development. A partial inhibitory effect on lipid oxidation development is concluded for the employment of a polyphenolic compound rich-film packaging when applied to farmed coho salmon.This research was carried out in the frame of the Project No. 2006 CL 0034 (2007–2008), granted by the U. Chile-CSIC Cooperation Program. Coho salmon fish was provided by Aquachile SA (Puerto Montt, Chile).Peer reviewe

Creació de continguts docents multimodals: La integració del text i la veu com a suport a la lectura

Memòria del projecte Creació de continguts docents multimodals, que ha experimentat amb la reedició d’uns materials docents en format accessible dins el context del Postgrau en Infància, protecció de la persona i adopció, integrat al Màster en Dret i Família i Infància de la Facultat de Dret de la Universitat de Barcelona, però amb la visió d’estendre l’experiència a molts d’altres ensenyaments. Com a resultat del projecte s’han publicat les 10 unitats del Mòdul d’Infància en format PDF accessible, DAISY i EPUB3, els dos darrers amb veu incorporada i s’han posat a disposició de l’alumnat del màster. També s’ha creat una memòria explicant el protocol de creació dels materials. Com a resultat s’ha demostrat que és viable, sostenible i altament recomanable la creació de versions accessibles de material docent dins el marc de la Universitat de Barcelona amb un cost realment baix.2014PID_UB/01

Performance evaluation of a real time OFDM radio over fiber system at 2.5 GHz using software defined radio SDR

This paper presents the implementation of an OFDM radio over fiber (RoF) system at 2.5 GHz using software defined radio (SDR). In this work, first we present an introduction of the main concepts about radio over fiber and an orthogonal frequency-division multiplexing (OFDM) system at 2.5 GHz, then we present a comparison of an OFDM RoF system in three scenarios, modifying the wireless distances and the optical fiber distance in order to evaluate the performance of the system taking into account the symbol error rate (SER) vs signal to noise ratio (SNR) curves

JADES: Detecting [OIII]λ4363λ4363 Emitters and Testing Strong Line Calibrations in the High-zz Universe with Ultra-deep JWST/NIRSpec Spectroscopy up to z∼9.5z \sim 9.5

© 2024 The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY), https://creativecommons.org/licenses/by/4.0/We present ten novel [OIII]λ4363 auroral line detections up to z ∼ 9.5 measured from ultra-deep JWST/NIRSpec MSA spectroscopy from the JWST Advanced Deep Extragalactic Survey (JADES). We leverage the deepest spectroscopic observations taken thus far with NIRSpec to determine electron temperatures and oxygen abundances using the direct Te method. We directly compare these results against a suite of locally calibrated strong-line diagnostics and recent high-z calibrations. We find the calibrations fail to simultaneously match our JADES sample, thus warranting a self-consistent revision of these calibrations for the high-z Universe. We find a weak dependence between R2 and O3O2 with metallicity, thus suggesting these line ratios are inefficient in the high-z Universe as metallicity diagnostics and degeneracy breakers. We find R3 and R23 are still correlated with metallicity, but we find a tentative flattening of these diagnostics, thus suggesting future difficulties when applying these strong line ratios as metallicity indicators in the high-z Universe. We also propose and test an alternative diagnostic based on a different combination of R3 and R2 with a higher dynamic range. We find a reasonably good agreement (median offset of 0.002 dex, median absolute offset of 0.13 dex) with the JWST sample at low metallicity, but future investigations are required on larger samples to probe past the turnover point. At a given metallicity, our sample demonstrates higher ionization and excitation ratios than local galaxies with rest-frame EWs(Hβ) ≈200 − 300 Å. However, we find the median rest-frame EWs(Hβ) of our sample to be ∼2× less than the galaxies used for the local calibrations. This EW discrepancy combined with the high ionization of our galaxies does not offer a clear description of [OIII]λ4363 production in the high-z Universe, thus warranting a much deeper examination into the factors influencing these processes.Peer reviewe

Giant tortoise genomes provide insights into longevity and age-related disease

© 2018, The Author(s), under exclusive licence to Springer Nature Limited. Giant tortoises are among the longest-lived vertebrate animals and, as such, provide an excellent model to study traits like longevity and age-related diseases. However, genomic and molecular evolutionary information on giant tortoises is scarce. Here, we describe a global analysis of the genomes of Lonesome George—the iconic last member of Chelonoidis abingdonii—and the Aldabra giant tortoise (Aldabrachelys gigantea). Comparison of these genomes with those of related species, using both unsupervised and supervised analyses, led us to detect lineage-specific variants affecting DNA repair genes, inflammatory mediators and genes related to cancer development. Our study also hints at specific evolutionary strategies linked to increased lifespan, and expands our understanding of the genomic determinants of ageing. These new genome sequences also provide important resources to help the efforts for restoration of giant tortoise populations

JADES: Insights into the low-mass end of the mass–metallicity–SFR relation at 3 < z < 10 from deep JWST/NIRSpec spectroscopy⋆

© 2024 The Author(s). Published by EDP Sciences. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY), https://creativecommons.org/licenses/by/4.0/We analysed the gas-phase metallicity properties of a sample of low-stellar-mass (log M⋆/M⊙ ≲ 9) galaxies at 3  6, with galaxies significantly less enriched than predicted given their M⋆ and SFR (with a median offset in log(O/H) of ∼0.5 dex, significant at ∼5σ). These observations are consistent with an enhanced stochasticity in the gas accretion and star-formation history of high-redshift systems, prompting us to reconsider the nature of the relationship between M⋆, O/H, and SFR in the early Universe.Peer reviewe

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

5to. Congreso Internacional de Ciencia, Tecnología e Innovación para la Sociedad. Memoria académica

El V Congreso Internacional de Ciencia, Tecnología e Innovación para la Sociedad, CITIS 2019, realizado del 6 al 8 de febrero de 2019 y organizado por la Universidad Politécnica Salesiana, ofreció a la comunidad académica nacional e internacional una plataforma de comunicación unificada, dirigida a cubrir los problemas teóricos y prácticos de mayor impacto en la sociedad moderna desde la ingeniería. En esta edición, dedicada a los 25 años de vida de la UPS, los ejes temáticos estuvieron relacionados con la aplicación de la ciencia, el desarrollo tecnológico y la innovación en cinco pilares fundamentales de nuestra sociedad: la industria, la movilidad, la sostenibilidad ambiental, la información y las telecomunicaciones. El comité científico estuvo conformado formado por 48 investigadores procedentes de diez países: España, Reino Unido, Italia, Bélgica, México, Venezuela, Colombia, Brasil, Estados Unidos y Ecuador. Fueron recibidas un centenar de contribuciones, de las cuales 39 fueron aprobadas en forma de ponencias y 15 en formato poster. Estas contribuciones fueron presentadas de forma oral ante toda la comunidad académica que se dio cita en el Congreso, quienes desde el aula magna, el auditorio y la sala de usos múltiples de la Universidad Politécnica Salesiana, cumplieron respetuosamente la responsabilidad de representar a toda la sociedad en la revisión, aceptación y validación del conocimiento nuevo que fue presentado en cada exposición por los investigadores. Paralelo a las sesiones técnicas, el Congreso contó con espacios de presentación de posters científicos y cinco workshops en temáticas de vanguardia que cautivaron la atención de nuestros docentes y estudiantes. También en el marco del evento se impartieron un total de ocho conferencias magistrales en temas tan actuales como la gestión del conocimiento en la universidad-ecosistema, los retos y oportunidades de la industria 4.0, los avances de la investigación básica y aplicada en mecatrónica para el estudio de robots de nueva generación, la optimización en ingeniería con técnicas multi-objetivo, el desarrollo de las redes avanzadas en Latinoamérica y los mundos, la contaminación del aire debido al tránsito vehicular, el radón y los riesgos que representa este gas radiactivo para la salud humana, entre otros

Autoevalaución y coevaluación del proceso del trabajo en equipo en el marco del EEES

Memoria ID-0134. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2015-2016

The global, regional, and national burden of adult lip, oral, and pharyngeal cancer in 204 countries and territories:A systematic analysis for the Global Burden of Disease Study 2019

Importance Lip, oral, and pharyngeal cancers are important contributors to cancer burden worldwide, and a comprehensive evaluation of their burden globally, regionally, and nationally is crucial for effective policy planning.Objective To analyze the total and risk-attributable burden of lip and oral cavity cancer (LOC) and other pharyngeal cancer (OPC) for 204 countries and territories and by Socio-demographic Index (SDI) using 2019 Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study estimates.Evidence Review The incidence, mortality, and disability-adjusted life years (DALYs) due to LOC and OPC from 1990 to 2019 were estimated using GBD 2019 methods. The GBD 2019 comparative risk assessment framework was used to estimate the proportion of deaths and DALYs for LOC and OPC attributable to smoking, tobacco, and alcohol consumption in 2019.Findings In 2019, 370 000 (95% uncertainty interval [UI], 338 000-401 000) cases and 199 000 (95% UI, 181 000-217 000) deaths for LOC and 167 000 (95% UI, 153 000-180 000) cases and 114 000 (95% UI, 103 000-126 000) deaths for OPC were estimated to occur globally, contributing 5.5 million (95% UI, 5.0-6.0 million) and 3.2 million (95% UI, 2.9-3.6 million) DALYs, respectively. From 1990 to 2019, low-middle and low SDI regions consistently showed the highest age-standardized mortality rates due to LOC and OPC, while the high SDI strata exhibited age-standardized incidence rates decreasing for LOC and increasing for OPC. Globally in 2019, smoking had the greatest contribution to risk-attributable OPC deaths for both sexes (55.8% [95% UI, 49.2%-62.0%] of all OPC deaths in male individuals and 17.4% [95% UI, 13.8%-21.2%] of all OPC deaths in female individuals). Smoking and alcohol both contributed to substantial LOC deaths globally among male individuals (42.3% [95% UI, 35.2%-48.6%] and 40.2% [95% UI, 33.3%-46.8%] of all risk-attributable cancer deaths, respectively), while chewing tobacco contributed to the greatest attributable LOC deaths among female individuals (27.6% [95% UI, 21.5%-33.8%]), driven by high risk-attributable burden in South and Southeast Asia.Conclusions and Relevance In this systematic analysis, disparities in LOC and OPC burden existed across the SDI spectrum, and a considerable percentage of burden was attributable to tobacco and alcohol use. These estimates can contribute to an understanding of the distribution and disparities in LOC and OPC burden globally and support cancer control planning efforts