155 research outputs found
Exopolysaccharides enriched in rare suggars: bacterial sources, production and applications
Mini ReviewMicrobial extracellular polysaccharides (EPS), produced by a wide range of bacteria, are
high molecular weight biopolymers, presenting an extreme diversity in terms of chemical
structure and composition. They may be used in many applications, depending on their
chemical and physical properties. A rather unexplored aspect is the presence of rare
sugars in the composition of some EPS. Rare sugars, such as rhamnose or fucose,
may provide EPS with additional biological properties compared to those composed of
more common sugar monomers. This review gives a brief overview of these specific EPS
and their producing bacteria. Cultivation conditions are summarized, demonstrating their
impact on the EPS composition, together with downstream processing. Finally, their use
in different areas, including cosmetics, food products, pharmaceuticals, and biomedical
applications, are discussedinfo:eu-repo/semantics/publishedVersio
Possibilitats de fer selecciĂł indirecta per producciĂł de farratge a la varietat lancaster de blat de moro
Effectiveness of a healthy lifestyle promotion program as adjunctive teletherapy for treatment-resistant major depression during COVID 19 pandemic: A randomized clinical trial protocol
INTRODUCTION: Treatment-resistant depression (TRD) has a high prevalence and can be exacerbated by poor physical health and economic hardships, which have become common stressors during the current COVID-19 pandemic. The therapeutic approaches used to treat these patients are not always available, may be not be accepted by some patients, and often require face-to-face interactions.
OBJECTIVE: The main aim of this study will be to evaluate the effectiveness of an Internet-based adjuvant lifestyle-based intervention for patients with TRD.
METHODS: This will be a parallel, randomized, and controlled clinical trial. A total of 180 patients with TRD will be randomly allocated (1:1:1) to 1 of 3 groups: treatment prescribed by the mental health team and written suggestions for lifestyle changes (placebo control group); treatment prescribed by the mental health team, written suggestions for lifestyle changes, and an 8-week mindfulness-based cognitive therapy program (active control group); or treatment prescribed by the mental health team, written suggestions for lifestyle changes, and an 8-week lifestyle change promotion program (intervention group). We will perform this study during the COVID-19 pandemic, and will administer interventions by teletherapy, and contact participants by telephone calls, text messages, and/or teleconferences. We will collect patient data using questionnaires administered at baseline, immediately after the intervention, and after 6 and 12 months. The primary outcome will be score on the Beck Depression Inventory-II. The secondary outcomes will be score on the Clinical Global Impressions Scale (used to quantify and track patient progress and treatment response over time) and health-related quality of life measured using the European Quality of Life-5 Dimensions Questionnaire.
DISCUSSION: Patients with TRD are especially vulnerable when face-to-face psychotherapy is unavailable. The main strength of the proposed study is the novelty of the intervention to be used as an adjuvant therapy. Our results may provide guidance for treatment of patients with TRD in future situations that require lockdown measures.
CLINICALTRIALS REGISTRATION NUMBER: NCT04428099
Manihot-EcoMap - Distribución ecogeográfica del género Manihot en Colombia - Implicaciones para la conservación y flujo de genes entre cultivo silvestres
Declining Lung Function and Cardiovascular Risk: The ARIC Study
Background: Pulmonary dysfunction predicts incident cardiovascular disease (CVD). Objectives: The purpose of this study was to evaluate whether longitudinal decline in lung function is associated with incident heart failure (HF), coronary heart disease (CHD), and stroke. Methods: Among 10,351 participants in the ARIC (Atherosclerosis Risk In Communities) study free of CVD, rapid lung function decline was defined as the greatest quartile (n = 2,585) of decline in either forced expiratory volume in 1 s (FEV1) (>1.9% decline/year) or forced vital capacity (FVC) (>2.1% decline/year) over 2.9 ± 0.2 years. The relationship between rapid decline in FEV1 or FVC and subsequent incident HF, CHD, stroke, or a composite of these was assessed using multivariable Cox regression adjusting for the baseline spirometry value, demographics, height, body mass index, heart rate, diabetes, hypertension, low-density lipoprotein, use of lipid-lowering medication, N-terminal fragment of prohormone for B-type natriuretic peptide, and smoking. Results: The mean age was 54 ± 6 years, 56% were women, and 81% were white. At 17 ± 6 years of follow-up, HF occurred in 14%, CHD 11%, stroke 6%, and the composite in 24%. Rapid decline in FEV1 and in FVC were both associated with a heightened risk of incident HF (hazard ratio [HR]: 1.17; 95% confidence interval [CI]: 1.04 to 1.33; p = 0.010; and HR: 1.27; 95% CI: 1.12 to 1.44; p < 0.001; respectively), with rapid decline in FEV1 most prognostic in the first year of follow-up (HR: 4.22; 95% CI: 1.34 to 13.26; p = 0.01). Rapid decline in FEV1 was also associated with incident stroke (HR: 1.25; 95% CI: 1.04 to 1.50; p = 0.015). Conclusions: A rapid decline in lung function, assessed by serial spirometry, is associated with a higher incidence of subsequent CVD, particularly incident HF
Developmental activities and the acquisition of superior anticipation and decision making in soccer players
Variaciones laterales de la estructura del anticlinal de Barbastro-Balaguer
El afloramiento de yesos y sales eocenas que constituyen el anticlinal de Barbastro-Balaguer presenta continuidad a lo largo de 150 km si bien la variaciĂłn lateral en tĂ©rminos estructurales es patente ya en la geologĂa de superficie. En este trabajo se presenta una sĂntesis cartográfica de la estructura y tres cortes que ilustran zonas concretas de los sectores occidental, central y oriental. Desde su terminaciĂłn periclinal al oeste, esta estructura se dibuja como un retrocabalgamiento y más adelante como un anticlinal que en ciertas zonas se desdobla en más de una estructura para culminar, al oeste, en un anticlinal suave cuya geometrĂa corresponde a grandes rasgos a un pliegue de adaptaciĂłn de falla. Mientras que el flanco sur presenta una traza continua y regular, el flanco norte del anticlinal de Barbastro- Balaguer mimetiza la traza del frente de las Sierras Marginales, lo que se traduce en una traza irregular con entrantes y salientes. Esta irregularidad podrĂa explicarse por el grado de interacciĂłn entre el frente de deformaciĂłn y la posiciĂłn y geometrĂa de los niveles de despegue eocenos que dependen, a su vez, de la extensiĂłn de los sistemas lacustres donde se sedimentaron
Photoproduction of mesons off nuclei
Recent results for the photoproduction of mesons off nuclei are reviewed.
These experiments have been performed for two major lines of research related
to the properties of the strong interaction. The investigation of nucleon
resonances requires light nuclei as targets for the extraction of the isospin
composition of the electromagnetic excitations. This is done with quasi-free
meson photoproduction off the bound neutron and supplemented with the
measurement of coherent photoproduction reactions, serving as spin and/or
isospin filters. Furthermore, photoproduction from light and heavy nuclei is a
very efficient tool for the study of the interactions of mesons with nuclear
matter and the in-medium properties of hadrons. Experiments are currently
rapidly developing due to the combination of high quality tagged (and
polarized) photon beams with state-of-the-art 4pi detectors and polarized
targets
Linea de base para la toma de desiciones en bioseguridad: desarrollo de un modelo para la evaluaciĂłn de flujo de genes caracterizaciĂłn molecular de la diversidad de yuca usando marcadores SSRs, ESTs, y SNPs
An actively vetoed Clover gamma-detector for nuclear astrophysics at LUNA
An escape-suppressed, composite high-purity germanium detector of the Clover
type has been installed at the Laboratory for Underground Nuclear Astrophysics
(LUNA) facility, deep underground in the Gran Sasso Laboratory, Italy. The
laboratory gamma-ray background of the Clover detector has been studied
underground at LUNA and, for comparison, also in an overground laboratory.
Spectra have been recorded both for the single segments and for the virtual
detector formed by online addition of all four segments. The effect of the
escape-suppression shield has been studied as well. Despite their generally
higher intrinsic background, escape-suppressed detectors are found to be well
suited for underground nuclear astrophysics studies. As an example for the
advantage of using a composite detector deep underground, the weak ground state
branching of the Ep = 223 keV resonance in the 24Mg(p,gamma)25Al reaction is
determined with improved precision.Comment: 8 pages, 6 figures, 3 tables; as accepted by Eur. Phys. J.
- …